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1. 发明申请

US20090253794A1 Fibroblast Activator, Collagen Production Promoter, Collagen Contraction Promoter, Hyaluronic Acid Production Promoter, ATP Production Promoter, Melanin Formation Inhibitor, and Agent for External Application to the Skin 审中-公开
标题翻译：成纤维细胞激活剂，胶原生成促进剂，胶原收缩启动子，透明质酸生产促进剂，ATP生产促进剂，黑色素形成抑制剂和外用于皮肤的药剂
公开(公告)号：US20090253794A1
公开(公告)日：2009-10-08
申请号：US11989194
申请日：2006-07-21
申请人： Jun Tomono , Takahisa Nakai , Toshihide Fujii
发明人： Jun Tomono , Takahisa Nakai , Toshihide Fujii
IPC分类号： A61K31/195
CPC分类号： A61Q19/08 , A61K8/44 , A61K31/195 , A61Q19/02
摘要： The present invention is a fibroblast activator, collagen production promoter, collagen contraction promoter, hyaluronic acid production promoter, ATP production promoter or melanin formation suppressor, which contains, as an active ingredient, at least one kind of compound selected from the group consisting of conagenin, a conagenin derivative, and a pharmaceutically acceptable salt thereof, as well as a composition (skin external preparation, cosmetic, pharmaceutical product or food, which is a composition for the improvement of wrinkles or a whitening composition) containing such activator, promoter or melanin formation suppressor.According to the present invention, a safe skin external preparation, cosmetic (cosmetic composition), pharmaceutical product or food, which shows a high wrinkle improving effect, can be provided, and a safe skin external preparation, cosmetic (cosmetic composition), pharmaceutical product or food, which shows a high whitening effect can be provided.
摘要翻译：本发明是一种成纤维细胞激活剂，胶原产生促进剂，胶原蛋白收缩促进剂，透明质酸产生促进剂，ATP生产促进剂或黑色素形成抑制剂，其含有至少一种选自下列基团的化合物作为活性成分：，配子衍生物及其药学上可接受的盐，以及含有这种活化剂，促进剂或黑色素的组合物（皮肤外用制剂，化妆品，药物产品或食品，其是用于改善皱纹或美白组合物的组合物）形成抑制器。根据本发明，可以提供显示出高皱纹改善效果的安全皮肤外用剂，化妆品（化妆品组合物），药品或食品，以及安全的皮肤外用剂，化妆品（化妆品组合物），药品或食物，其可以提供高的美白效果。

2. 发明申请

US20120264687A1 MODIFIED ERYTHROPOIETIN TO WHICH WATER-SOLUBLE LONG-CHAIN MOLECULE IS ADDED 审中-公开
标题翻译：添加了可溶性长链分子的改良的红细胞膜蛋白
公开(公告)号：US20120264687A1
公开(公告)日：2012-10-18
申请号：US13395534
申请日：2010-09-15
申请人： Nobutaka Tani , Toshihide Fujii , Hiroyuki Watanabe , Hirofumi Maeda
发明人： Nobutaka Tani , Toshihide Fujii , Hiroyuki Watanabe , Hirofumi Maeda
IPC分类号： A61K38/18 , A61P7/06
CPC分类号： A61K9/0019 , A61K38/1816 , A61K47/60
摘要： An object of the invention is to provide a pharmaceutical composition that contains erythropoietin as the active ingredient and has, when administered in humans and/or animals, a hematopoietic effect that lasts for not less than seven days. The invention provides a pharmaceutical composition containing, in an amount equal to not less than 50% of the total erythropoietin, erythropoietin to which two or more water-soluble long-chain molecules are added. The invention also provides a pharmaceutical composition containing erythropoietin to which a water-soluble long-chain molecule is added, wherein the water-soluble long-chain molecule has a molecular weight of not less than 30 kDa. The invention further provides a pharmaceutical composition containing erythropoietin to which a water-soluble long-chain molecule is added, wherein the water-soluble long-chain molecule has a branched chain.
摘要翻译：本发明的目的是提供一种含有促红细胞生成素作为活性成分并且在人和/或动物中施用时持续不少于7天的造血作用的药物组合物。本发明提供一种药物组合物，其含量等于不少于总促红细胞生成素的50％，红细胞生成素，其中加入了两种或更多种水溶性长链分子。本发明还提供含有促红细胞生成素的药物组合物，其中加入水溶性长链分子，其中水溶性长链分子的分子量不小于30kDa。本发明还提供含有促红细胞生成素的药物组合物，其中加入水溶性长链分子，其中所述水溶性长链分子具有支链。

3. 发明申请

US20100151424A1 ARTIFICIAL MOLAR TEETH 审中-公开
标题翻译：人造迷迭香
公开(公告)号：US20100151424A1
公开(公告)日：2010-06-17
申请号：US12638405
申请日：2009-12-15
申请人： Yusei KADOBAYASHI , Toshihide Fujii
发明人： Yusei KADOBAYASHI , Toshihide Fujii
IPC分类号： A61C13/10
CPC分类号： A61C13/08 , A61C13/097 , A61C13/10
摘要： The invention provides artificial teeth arranged in plates attached in an oral cavity as a dental prosthetic appliance, in which one or more linear arrangement direction indication parts showing the arrangement direction in the plates are provided on an occlusal plane of each of the molar teeth. At least one set of arrangement direction indication parts of the adjacent molar teeth is configured so as to extend generally in parallel direction. At least one set of arrangement direction indication parts of the antagonist upper molar teeth and lower molar teeth is configured so as to extend generally in parallel direction. The artificial molar teeth are arranged at an appropriate position according to the oral cavity environment of each patient, without requiring advanced skills and experiences, being applicable to various arrangement of artificial teeth.
摘要翻译：本发明提供了一种布置在作为牙科修复器具的口腔中的人造牙齿，其中在每个臼齿的咬合平面上提供了一个或多个在板上显示排列方向的线性排列方向指示部分。相邻摩擦齿的至少一组布置方向指示部分被构造成大致沿平行方向延伸。拮抗剂上臼齿和下臼齿的至少一组排列方向指示部分构造成大致沿平行方向延伸。人造臼齿根据每个病人的口腔环境排列在适当的位置，无需先进的技能和经验，适用于人造牙齿的各种布置。

4. 发明申请

US20110207085A1 SET OF ARTIFICIAL TEETH OF ANTERIOR TEETH LINEARLY CONTACTING WITH EACH OTHER 有权
标题翻译：一组与其他人线性接触的前庭牙科的人造牙科
公开(公告)号：US20110207085A1
公开(公告)日：2011-08-25
申请号：US13102392
申请日：2011-05-06
申请人： Yusei KADOBAYASHI , Toshihide Fujii
发明人： Yusei KADOBAYASHI , Toshihide Fujii
IPC分类号： A61C13/10
CPC分类号： A61C13/00 , A61C13/08
摘要： In a set of artificial teeth, at least one of mutually adjacent artificial anterior teeth includes abutting faces which contacts linearly with the other one so as to form abutting lines and capable of continuously moving the positions of the linear contact, the abutting faces being formed of any one of circular columnar surface, elliptical columnar surface, and conical surface.
摘要翻译：在一组人造牙齿中，相互相邻的人造前牙中的至少一个包括与另一个直线接触的邻接面，以形成邻接线并能够连续地移动线性接触的位置，邻接面由任何一个圆柱形表面，椭圆柱形表面和圆锥形表面。

5. 发明授权

US07918665B2 Artificial anterior tooth having frictional surface at lingual side, and a set of artificial teeth, and denture 有权
标题翻译：人造前牙在舌侧有摩擦表面，一组人造牙齿和义齿
公开(公告)号：US07918665B2
公开(公告)日：2011-04-05
申请号：US12634993
申请日：2009-12-10
申请人： Yusei Kadobayashi , Toshihide Fujii
发明人： Yusei Kadobayashi , Toshihide Fujii
IPC分类号： A61C13/08
CPC分类号： A61C13/097 , A61C13/10
摘要： An artificial anterior tooth capable of grinding food is provided. The lingual side of an artificial anterior tooth is provided with a protuberance for forming a frictional surface dented in an arch shape as seen from the mesiodistal direction, and the labial side of an opposite artificial lower tooth is provided with a protuberance for forming a sliding surface abutting the frictional surface and sliding on the frictional surface by a sliding motion of the upper and lower jaws.
摘要翻译：提供能够研磨食物的人造前牙。人造前牙的舌侧设置有用于形成从中间方向观察时以拱形凹陷的摩擦面的突起，并且相对的人造下齿的阴唇侧设置有用于形成滑动面的突起通过上下爪的滑动运动抵靠摩擦表面并在摩擦表面上滑动。

6. 发明申请

US20090301346A1 DENTAL RESIN-BASED CEMENT COMPOSITION 审中-公开
标题翻译：基于树脂的水泥组合物
公开(公告)号：US20090301346A1
公开(公告)日：2009-12-10
申请号：US12448049
申请日：2006-12-06
申请人： Hisaki Tanaka , Toshihide Fujii , Yoshiaki Kohro , Keisuke Torii , Mikito Deguchi
发明人： Hisaki Tanaka , Toshihide Fujii , Yoshiaki Kohro , Keisuke Torii , Mikito Deguchi
IPC分类号： A61K6/02
CPC分类号： A61K6/0023 , A61K6/0017 , A61K6/083 , A61K6/09 , C08L33/04 , C08L75/16
摘要： The present invention provides a dental resin cement composition comprising at least two kinds of pastes, one kind of a paste comprising (a) 20 to 50 parts by weight of a polymerizable monomer composition and (b) 50 to 80 parts by weight of a filler consisting of an inorganic compound, or an organic composite comprising an inorganic compound, amounts of (a) and (b) being based on conversion of 100 parts by weight of the dental resin-based cement composition paste, and the filler (b) comprising (c) 2.0 to 10.0 parts by weight of fine silica particles based on the above conversion, and having (d) a yield viscosity of from 100 to 3,000 [Pa·s], and (e) a thixotropy index of 3.0 or more; and another kind of a paste having the same constituent features (a) to (c) and (e) except that the paste has (d) a yield viscosity of from 70 to 4,000 [Pa·s], wherein upon use, the at least two kinds of pastes are used by mixing them.
摘要翻译：本发明提供一种牙科用树脂水泥组合物，其包含至少两种糊剂，一种糊剂，其包含（a）20至50重量份的可聚合单体组合物和（b）50至80重量份的填料由无机化合物或包含无机化合物的有机复合物组成，（a）和（b）的量是基于100重量份的基于牙科树脂的水泥组合物糊料的转化率和填料（b），其包含（c）基于上述转化率为2.0至10.0重量份的二氧化硅微粒，并且（d）100至3,000 [Pa.s]的屈服粘度，和（e）触变指数为3.0以上; 和具有相同组成特征（a）至（c）和（e）的另一种糊状物，不同之处在于糊料具有（d）70至4,000 [Pa.s]的屈服粘度，其中在使用时，混合使用最少两种糊剂。

7. 发明授权

US07611059B2 Code reading device and program 有权
标题翻译：代码阅读器和程序
公开(公告)号：US07611059B2
公开(公告)日：2009-11-03
申请号：US11153634
申请日：2005-06-15
申请人： Yoshinobu Kobayashi , Kumiko Oono , Toshihide Fujii
发明人： Yoshinobu Kobayashi , Kumiko Oono , Toshihide Fujii
IPC分类号： G06K7/10
CPC分类号： G06K7/10881 , G06K7/1095
摘要： On a display window that displays code patterns that are read at a time, a code reading device allows the code pattern that is successfully decoded to be visually confirmed with ease. In a handy terminal, when an image scanner reads code patterns at a time in response to a trigger operation, a CPU performs decoding processes for each code pattern and determines whether the decoding processes have been successfully completed or not based on the decoding results so as to display an identifying mark indicating the determination result in association with the image of each code pattern.
摘要翻译：在显示窗口中，显示一次读取的代码模式，代码读取装置允许成功解码的代码模式被轻松的视觉确认。在方便的终端中，当图像扫描仪响应于触发操作一次读取代码模式时，CPU对每个代码模式执行解码处理，并且基于解码结果确定解码处理是否已经成功完成，从而与每个代码模式的图像相关联地显示表示确定结果的识别标记。

8. 发明申请

US20100151422A1 ARTIFICIAL ANTERIOR TOOTH HAVING FRICTIONAL SURFACE AT LINGUAL SIDE, AND A SET OF ARTIFICIAL TEETH, AND DENTURE 有权
标题翻译：人造牙齿在一侧有摩擦表面，一组人造牙齿和牙齿
公开(公告)号：US20100151422A1
公开(公告)日：2010-06-17
申请号：US12634993
申请日：2009-12-10
申请人： Yusei KADOBAYASHI , Toshihide Fujii
发明人： Yusei KADOBAYASHI , Toshihide Fujii
IPC分类号： A61C13/10
CPC分类号： A61C13/097 , A61C13/10
摘要： Provided is an artificial anterior tooth capable of grinding the food. The lingual side of an artificial anterior is provided with a protuberance for forming a frictional surface dented in an arch shape as seen from the mesiodistal direction, and the labial side of an opposite artificial lower tooth is provided with a protuberance for forming a sliding surface abutting on the frictional surface and sliding on the frictional surface by sliding motion of upper and lower jaws.
摘要翻译：提供能够研磨食物的人造前牙。人造前缘的舌侧具有突起，用于形成从中间方向观察时以拱形凹陷的摩擦面，并且相对的人造下齿的阴唇侧设置有突起，用于形成滑动面邻接在摩擦表面上，并通过上下爪的滑动运动在摩擦表面上滑动。

9. 发明申请

US20100101453A1 One-pack type dental adhesive composition 有权
标题翻译：一包式牙科粘合剂组合物
公开(公告)号：US20100101453A1
公开(公告)日：2010-04-29
申请号：US12585974
申请日：2009-09-30
申请人： Hisaki Tanaka , Toshihide Fujii , Yutaka Yamaguchi , Mikito Deguchi
发明人： Hisaki Tanaka , Toshihide Fujii , Yutaka Yamaguchi , Mikito Deguchi
IPC分类号： A61K6/00
CPC分类号： C09J163/00 , A61C2202/00 , A61C2202/01 , A61K6/0029 , C08G77/20 , C08L83/04
摘要： Disclosed is a one-pack type dental adhesive composition comprising: (a) 1.0 to 40.0 parts by weight of a silane coupling agent, (b) 0.01 to 0.4 part by weight of a weak acidic compound which is at least one of organic acid, boric acid and silicic acid, and has an acid dissociation exponent pKa of 3 or more in the form of an aqueous solution, (c) 0.01 to 0.4 part by weight of a strong acidic compound which is at least one of HF, HCl, HBr, HI, HNO3, HClO3, HClO4, HBrO4, HMnO4, H2SO4 and H3PO4 and has an acid dissociation exponent pKa of less than 3, (d) 0.1 to 5.0 part by weight of water, and (e) 20.0 to 99.0 parts by weight of a volatile organic solvent.
摘要翻译：公开了一种单组分型牙科粘合剂组合物，其包含：（a）1.0至40.0重量份的硅烷偶联剂，（b）0.01至0.4重量份的弱酸性化合物，其为有机酸，硼酸和硅酸，并且酸溶解指数pKa为水溶液形式的3或更多，（c）0.01至0.4重量份的强酸性化合物，其为HF，HCl，HBr中的至少一种，HI，HNO 3，HClO 3，HClO 4，HBrO 4，HMnO 4，H 2 SO 4和H 3 PO 4，并且具有小于3的酸解离指数pKa，（d）0.1至5.0重量份的水，和（e）20.0至99.0重量份的挥发性有机溶剂。

10. 发明申请

US20090076182A1 One-pack type dental adhesive composition 有权
标题翻译：一包式牙科粘合剂组合物
公开(公告)号：US20090076182A1
公开(公告)日：2009-03-19
申请号：US12230225
申请日：2008-08-26
申请人： Hisaki Tanaka , Toshihide Fujii , Yutaka Yamaguchi , Mikito Deguchi
发明人： Hisaki Tanaka , Toshihide Fujii , Yutaka Yamaguchi , Mikito Deguchi
IPC分类号： A61K6/00 , C08F4/00
CPC分类号： A61K6/0023 , A61K6/083 , A61K6/093 , C08L33/10 , C08L83/10
摘要： An object of the present invention is to provide a one-pack type dental adhesive composition which can exhibit excellent adhesion to any material, for example, dental ceramics, organic composites containing inorganic compounds, dental noble metals and dental non-noble metals, and also has excellent storage stability.Disclosed is a one-pack type dental adhesive composition comprising a silane coupling agent as a component (a), an acidic group-containing polymerizable monomer as a component (b), a sulfur atom-containing polymerizable monomer as a component (d), and other components.
摘要翻译：本发明的目的是提供一种能够对任何材料，例如牙科陶瓷，含有无机化合物的有机复合物，牙科贵金属和牙科非贵金属的材料表现出优异粘合性的单组分型牙科粘合剂组合物，以及具有优良的储存稳定性。公开了一种单组分型牙科粘合剂组合物，其包含作为组分（a）的硅烷偶联剂，作为组分（b）的含酸性基团的可聚合单体，作为组分（d）的含硫原子的可聚合单体）和其他组件。

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