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1. 发明授权

US06903869B2 Illumination system for microscopy and observation or measuring method using the same 有权
标题翻译：用于显微镜和观察的照明系统或使用其的测量方法
公开(公告)号：US06903869B2
公开(公告)日：2005-06-07
申请号：US10301631
申请日：2002-11-22
申请人： Takashi Fukano , Atsushi Miyawaki , Keiji Shimizu , Yoshihiro Kawano
发明人： Takashi Fukano , Atsushi Miyawaki , Keiji Shimizu , Yoshihiro Kawano
IPC分类号： G01N21/64 , G02B21/06 , G02B21/16 , G02B21/00
CPC分类号： G02B21/16
摘要： An illumination system for microscopy includes a light source, a first spectral element dispersing light from the light source, a reflecting member selectively reflecting light dispersed by the first spectral element, a second spectral element combining light reflected by the reflecting member, a dichroic mirror, an objective lens, and an image sensor. The first spectral element is placed at the front focal point of a first lens, the reflecting member is placed at a position where the back focal point of the first lens coincides with the front focal point of a second lens, and the second spectral element is placed at the back focal point of the second lens.
摘要翻译：用于显微镜的照明系统包括光源，分散来自光源的光的第一光谱元件，选择性地反射由第一光谱元件分散的光的反射部件，组合由反射部件反射的光的第二光谱元件，二向色镜，物镜和图像传感器。第一光谱元件被放置在第一透镜的前焦点处，反射部件被放置在第一透镜的后焦点与第二透镜的前焦点重合的位置，第二光谱元件放置在第二透镜的后焦点处。

2. 发明授权

US07315413B2 Illumination apparatus for microscope 有权
标题翻译：显微镜照明装置
公开(公告)号：US07315413B2
公开(公告)日：2008-01-01
申请号：US11269408
申请日：2005-11-08
申请人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
发明人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
IPC分类号： G02B21/06 , G02B21/00
CPC分类号： G02B27/144 , G02B21/16 , G02B27/1006 , G02B27/145
摘要： An illumination apparatus for a microscope includes a light source portion that projects a light beam, two splitting elements that split the light beam into three, wavelength selection elements that independently select transmission wavelengths of the three light beams, shutters that independently shield or guide the three light beams, a first combining element that combines optical paths of two light beams, a second combining element that combines an optical path of the remaining light beam with a combined optical path, a pinhole that is located on an optical path between the first and second combining elements and has an aperture that selectively transmits only part of a light beam, and a projection optical system that applies a light beam from the second combining element to a sample and, when applying a light beam from the pinhole to the sample, projects the aperture of the pinhole onto the sample.
摘要翻译：用于显微镜的照明装置包括投影光束的光源部分，将光束分成三个的分离元件，独立地选择三个光束的透射波长的波长选择元件，独立地屏蔽或引导三个光束的百叶窗光束，组合两个光束的光路的第一组合元件，将剩余光束的光路与组合光路组合的第二组合元件，位于第一和第二光束之间的光路上的针孔组合元件并且具有仅选择性地仅透射光束的一部分的孔径;以及投影光学系统，其将来自第二组合元件的光束施加到样本，并且当将来自针孔的光束施加到样品时，针孔的孔径到样品上。

3. 发明申请

US20070008615A1 Illumination apparatus for microscope and image processing apparatus using the same 有权
公开(公告)号：US20070008615A1
公开(公告)日：2007-01-11
申请号：US11520150
申请日：2006-09-13
申请人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
发明人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
IPC分类号： G02B21/06
CPC分类号： G02B21/06 , G02B21/16 , G02B21/365
摘要： An illumination apparatus for a microscope and an image processing apparatus using the illumination apparatus include a light source, a semi-transmissive mirror splitting a light beam from the light source into two beams of the first and second irradiation light, two excitation filters selecting the wavelengths of the first and second irradiation light, a semi-transmissive mirror synthesizing individual beams of the first and second irradiation light whose wavelengths are selected, into a single beam, a dichroic mirror directing a light beam synthesized by the semi-transmissive mirror toward a specimen and transmitting light from the specimen, an objective lens, cameras imaging fluorescent light from the specimen after being separated into fluorescent light excited by the first and second wavelengths, and an image processing section processing fluorescent images formed by imaging elements.

4. 发明申请

US20060098418A1 Illumination apparatus for microscope 有权
标题翻译：显微镜照明装置
公开(公告)号：US20060098418A1
公开(公告)日：2006-05-11
申请号：US11269408
申请日：2005-11-08
申请人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
发明人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
IPC分类号： G01D11/28
CPC分类号： G02B27/144 , G02B21/16 , G02B27/1006 , G02B27/145
摘要： An illumination apparatus for a microscope includes a light source portion that projects a light beam, two splitting elements that split the light beam into three, wavelength selection elements that independently select transmission wavelengths of the three light beams, shutters that independently shield or guide the three light beams, a first combining element that combines optical paths of two light beams, a second combining element that combines an optical path of the remaining light beam with a combined optical path, a pinhole that is located on an optical path between the first and second combining elements and has an aperture that selectively transmits only part of a light beam, and a projection optical system that applies a light beam from the second combining element to a sample and, when applying a light beam from the pinhole to the sample, projects the aperture of the pinhole onto the sample.
摘要翻译：用于显微镜的照明装置包括投影光束的光源部分，将光束分成三个的分离元件，独立地选择三个光束的透射波长的波长选择元件，独立地屏蔽或引导三个光束的百叶窗光束，组合两个光束的光路的第一组合元件，将剩余光束的光路与组合光路组合的第二组合元件，位于第一和第二光束之间的光路上的针孔组合元件并且具有仅选择性地仅透射光束的一部分的孔径;以及投影光学系统，其将来自第二组合元件的光束施加到样本，并且当将来自针孔的光束施加到样品时，针孔的孔径到样品上。

5. 发明授权

US07277566B2 Microscope system 失效
标题翻译：显微镜系统
公开(公告)号：US07277566B2
公开(公告)日：2007-10-02
申请号：US10662355
申请日：2003-09-16
申请人： Atsushi Miyawaki , Takashi Fukano
发明人： Atsushi Miyawaki , Takashi Fukano
IPC分类号： G06K9/00
CPC分类号： G02B21/082 , G01B11/24 , G01B11/25
摘要： A microscope system comprises: a control means (18) capable of generating electric control signals (18a); a spatial modulator means (7) having an illuminated surface (7a) to be illuminated by light emitted by a light source (1), and capable of receiving the electric control signal and of spatially modulating reflection characteristic or transmission characteristic of the illuminated surface by a spatial frequency specified by the electric control signal; an illuminating optical means (8, 11) for illuminating a specimen (12) with light spatially modulated by the spatial modulator means; an image detecting means (15) for detecting a signal image formed by signal light emitted by the specimen illuminated by the illuminating optical means; and an arithmetic means (16) for processing signal images formed by using the spatial frequency of at least three different phases set by the control means and detected by the image detecting means to obtain an optical sectioned image.
摘要翻译：显微镜系统包括：能够产生电控信号的控制装置（18）; 空间调制器装置（7）具有被光源（1）发射的光照射的照明表面（7a），并且能够接收电控制信号和空间调制被照射表面的反射特性或透射特性通过由电控信号指定的空间频率; 用于通过由空间调制器装置空间调制的光照射样本（12）的照明光学装置（8,11）; 图像检测装置，用于检测由照明光学装置照射的样本发出的信号光形成的信号图像; 以及用于处理通过使用由控制装置设置并由图像检测装置检测的至少三个不同相位的空间频率形成的信号图像以获得光学分割图像的算术装置（16）。

6. 发明授权

US07236298B2 Illumination apparatus for microscope and image processing apparatus using the same 有权
标题翻译：用于显微镜的照明装置和使用其的图像处理装置
公开(公告)号：US07236298B2
公开(公告)日：2007-06-26
申请号：US11520150
申请日：2006-09-13
申请人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
发明人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
IPC分类号： G02B21/06
CPC分类号： G02B21/06 , G02B21/16 , G02B21/365
摘要： An illumination apparatus for a microscope and an image processing apparatus using the illumination apparatus include a light source, a semi-transmissive mirror splitting a light beam from the light source into two beams of the first and second irradiation light, two excitation filters selecting the wavelengths of the first and second irradiation light, a semi-transmissive mirror synthesizing individual beams of the first and second irradiation light whose wavelengths are selected, into a single beam, a dichroic mirror directing a light beam synthesized by the semi-transmissive mirror toward a specimen and transmitting light from the specimen, an objective lens, cameras imaging fluorescent light from the specimen after being separated into fluorescent light excited by the first and second wavelengths, and an image processing section processing fluorescent images formed by imaging elements.
摘要翻译：用于显微镜的照明装置和使用该照明装置的图像处理装置包括光源，将来自光源的光束分成两束第一和第二照射光的半透射镜，两个激发滤光器选择波长第一和第二照射光的第一和第二照射光的半透射镜将将波长选择的第一和第二照射光的各个光束合成为单个光束，将由半透射镜合成的光束引向样品的二向色镜以及透射来自所述样本的物体，物镜，将被分离成由所述第一和第二波长激发的荧光的荧光从所述样本成像的摄像机，以及处理由成像元件形成的荧光图像的图像处理部。

7. 发明授权

US07126752B2 Illumination apparatus for microscope and image processing apparatus using the same 有权
标题翻译：用于显微镜的照明装置和使用其的图像处理装置
公开(公告)号：US07126752B2
公开(公告)日：2006-10-24
申请号：US10718884
申请日：2003-11-20
申请人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
发明人： Atsushi Miyawaki , Takashi Fukano , Yasushi Aono
IPC分类号： G02B21/00 , G02B21/06
CPC分类号： G02B21/06 , G02B21/16 , G02B21/365
摘要： An illumination apparatus for a microscope and an image processing apparatus using the illumination apparatus include a light source, a semi-transmissive mirror splitting a light beam from the light source into two beams of the first and second irradiation light, two excitation filters selecting the wavelengths of the first and second irradiation light, a semi-transmissive mirror synthesizing individual beams of the first and second irradiation light whose wavelengths are selected, into a single beam, a dichroic mirror directing a light beam synthesized by the semi-transmissive mirror toward a specimen and transmitting light from the specimen, an objective lens, cameras imaging fluorescent light from the specimen after being separated into fluorescent light excited by the first and second wavelengths, and an image processing section processing fluorescent images formed by imaging elements.
摘要翻译：用于显微镜的照明装置和使用该照明装置的图像处理装置包括光源，将来自光源的光束分成两束第一和第二照射光的半透射镜，两个激发滤光器选择波长第一和第二照射光的第一和第二照射光的半透射镜将将波长选择的第一和第二照射光的各个光束合成为单个光束，将由半透射镜合成的光束引向样品的二向色镜以及透射来自所述样本的物体，物镜，将被分离成由所述第一和第二波长激发的荧光的荧光从所述样本成像的摄像机，以及处理由成像元件形成的荧光图像的图像处理部。

8. 发明授权

US4269323A Heat insulated tank 失效
标题翻译：隔热箱
公开(公告)号：US4269323A
公开(公告)日：1981-05-26
申请号：US947696
申请日：1978-10-02
申请人： Nobuyoshi Ito , Hiroshi Morishita , Minoru Morita , Takashi Fukano
发明人： Nobuyoshi Ito , Hiroshi Morishita , Minoru Morita , Takashi Fukano
IPC分类号： C04B41/50 , F17C3/08 , B65D90/04
CPC分类号： F17C3/08 , C04B41/5089 , F17C2201/0104 , F17C2201/0128 , F17C2203/032 , F17C2203/0391 , F17C2203/0607 , F17C2203/0629 , F17C2221/011 , F17C2221/014 , F17C2221/033 , F17C2223/0161 , F17C2223/033 , F17C2260/024 , Y10S220/901 , Y10T428/231 , Y10T428/24537 , Y10T428/24612 , Y10T428/24999
摘要： A heat insulated tank is disclosed having inner and outer walls between which a supporting material is interposed. The material comprises a molding of alkaline earth metal silicates or a molding of composite material based thereon having a continuous open cell structure and subjected to heat treatment under vacuum. Inside and outside faces of said supporting material are provided with a suitable number of grooves. The entire surface of said supporting material is impregnated with a solution of sodium silicate, potassium silicate or ethyl silicate and subjected to baking.The supporting material has a high insulating capability and a high resistance to compression, thus it is applicable to square shaped tanks in addition to conventional spherical or cylindrical ones. The tank is easy to manufacture with increased storage capacity.
摘要翻译：公开了一种绝热罐，其具有插入有支撑材料的内壁和外壁。该材料包括碱土金属硅酸盐的模制品或其上具有连续开孔结构的复合材料的模制件，并在真空下进行热处理。所述支撑材料的内表面和外表面设置有适当数量的凹槽。所述支撑材料的整个表面用硅酸钠，硅酸钾或硅酸乙酯溶液浸渍并进行烘烤。支撑材料具有高绝缘能力和高抗压缩性，因此除了常规的球形或圆柱形罐之外，其可应用于方形罐。储罐易于制造，储存能力增加。

9. 发明授权

US5943134A Method of measuring thickness and refractive indices of component layers of laminated structure and measuring apparatus for carrying out the same 失效
$Method of measuring thickness and refractive indices of component layers of laminated structure and measuring apparatus for carrying out the same$
标题翻译：测量叠层结构件组件层厚度和折射率的方法及其实施方法
公开(公告)号：US5943134A
公开(公告)日：1999-08-24
申请号：US877502
申请日：1997-06-17
申请人： Ichirou Yamaguchi , Takashi Fukano
发明人： Ichirou Yamaguchi , Takashi Fukano
IPC分类号： G01B11/06 , G01N21/41 , G01B9/02
CPC分类号： G01B11/0675 , G01N21/45
摘要： A light beam emitted by a light source is projected through a collimator lens, a beam splitter and an objective on a sample having a laminated structure. The light beam reflected from the sample travels through the beam splitter to a detector and the detector provides a confocal signal. The detector provides an interference signal upon the reception of the reflected light beam and a reference light beam reflected by a reference mirror. The sample and the reference mirror are moved on the basis of the confocal signal and the interference signal, and the thickness and the refractive index of layer of the sample are determined on the basis of the respective displacements of the sample and the reference mirror.
摘要翻译：由光源发射的光束通过准直透镜，分束器和具有层叠结构的样品上的物镜投影。从样品反射的光束穿过分束器到达检测器，检测器提供共焦信号。检测器在接收到反射光束和由参考反射镜反射的参考光束时提供干涉信号。基于共聚焦信号和干涉信号移动样品和参考反射镜，并且基于样品和参考反射镜的相应位移来确定样品层的厚度和折射率。

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