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1. 发明公开

EP2921489A1 2-PYRIDONE COMPOUND 有权
标题翻译： 2-吡啶酮VERBINDUNG
公开(公告)号：EP2921489A1
公开(公告)日：2015-09-23
申请号：EP13855534.7
申请日：2013-11-12
申请人： Taisho Pharmaceutical Co., Ltd. , Nissan Chemical Industries, Ltd.
发明人： KURODA, Shoichi , IMAI, Yudai , KAWAGUCHI, Takanori , FUSEGI, Keiko , BOHNO, Masahiro , ASANUMA, Hajime , CHONAN, Tomomichi , SATO, Nagaaki , MONMA, Souichi , SASAKO, Shigetada , MIZUTANI, Marie , ITOH, Shin , OKADA, Takumi , OTA, Hirofumi , ISHIYAMA, Seishi
IPC分类号： C07D401/06 , A61K31/4439 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P13/12 , A61P27/02 , A61P43/00
CPC分类号： C07D401/06 , A61K31/4439
摘要： This 2-pyridone compound represented by formula [1] or a tautomer of said compound, or a pharmaceutically acceptable salt of said compound or said tautomer, or a solvate of said compound or the like has a superior GK-activating effect and is useful as a pharmaceutical.
摘要翻译：由式[1]表示的2-吡啶酮化合物或所述化合物的互变异构体或所述化合物或所述互变异构体的药学上可接受的盐，或所述化合物等的溶剂合物具有优异的GK-活化作用，可用作制药。

2. 发明申请

WO2007010954A1 THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS 审中-公开
标题翻译：噻吩类化合物和血栓素受体激活剂
公开(公告)号：WO2007010954A1
公开(公告)日：2007-01-25
申请号：PCT/JP2006/314317
申请日：2006-07-13
申请人： NISSAN CHEMICAL INDUSTRIES, LTD. , MIYAJI, Katsuaki , YANAGIHARA, Kazufumi , SHIGETA, Yukihiro , IWAMOTO, Shunsuke , HORIKAWA, Masato , HIROKAWA, Yutaka , OWADA, Shingo , NAKANO, Satoshi , OTA, Hirofumi , ISHIWATA, Norihisa
发明人： MIYAJI, Katsuaki , YANAGIHARA, Kazufumi , SHIGETA, Yukihiro , IWAMOTO, Shunsuke , HORIKAWA, Masato , HIROKAWA, Yutaka , OWADA, Shingo , NAKANO, Satoshi , OTA, Hirofumi , ISHIWATA, Norihisa
IPC分类号： C07D333/32 , C07D409/12
CPC分类号： C07D409/14 , C07D333/32 , C07D333/38 , C07D413/14
摘要： ABSTRACT A compound represented by the formula (I) (wherein R 1 , R 2 , R 3 and R 4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.
摘要翻译：摘要一种由式（I）表示的化合物（其中R 1，R 2，R 3和R 4 如说明书中所定义），化合物或其溶剂合物的互变异构体，前药或药学上可接受的盐。

3. 发明申请

WO2006062240A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS 审中-公开
标题翻译：作为血栓素受体激活剂的3-乙酰基乙酰胺取代的杂环化合物
公开(公告)号：WO2006062240A1
公开(公告)日：2006-06-15
申请号：PCT/JP2005/022907
申请日：2005-12-07
申请人： NISSAN CHEMICAL INDUSTRIES, LTD. , MIYAJI, Katsuaki , SHIGETA, Yukihiro , NAKANO, Satoshi , IWAMOTO, Shunsuke , HIROKAWA, Yutaka , OTA, Hirofumi , YANAGIHARA, Kazufumi , OWADA, Shingo , ISHIWATA, Norihisa
发明人： MIYAJI, Katsuaki , SHIGETA, Yukihiro , NAKANO, Satoshi , IWAMOTO, Shunsuke , HIROKAWA, Yutaka , OTA, Hirofumi , YANAGIHARA, Kazufumi , OWADA, Shingo , ISHIWATA, Norihisa
IPC分类号： C07D333/32 , C07D231/18 , A61K31/415 , A61P7/00
CPC分类号： C07D409/12 , C07D333/32 , C07D401/12
摘要： A compound represented by the formula (1): wherein A, B, R 1 , L 1 , R 2 , L 2 , L 3 , Y, L 4 , R 3 and X are the same as defined in the description, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.
摘要翻译：由式（1）表示的化合物：其中A，B，R 1，L 1，R 2，L 2， L，3，Y，L 4，R 3和X与说明书中定义的相同，互变异构体，化合物或其溶剂合物的前药或药学上可接受的盐。

4. 发明授权

EP3124468B1 FLUORENE DERIVATIVE AND USE THEREOF 有权
公开(公告)号：EP3124468B1
公开(公告)日：2018-12-12
申请号：EP15770297.8
申请日：2015-03-23
申请人： Nissan Chemical Industries, Ltd.
发明人： OTA, Hirofumi , ENDO, Toshiyuki
IPC分类号： C07C217/76 , C09D5/22 , H01L51/00 , H01L51/50
CPC分类号： H01L51/006 , C07C209/68 , C07C211/54 , C07C213/08 , C07C217/76 , C07C2603/18 , C09D5/22 , C09D5/24 , H01L51/0052 , H01L51/5056 , H01L51/506 , H01L51/5076 , H01L51/5088
摘要： Provided is the fluorene derivative represented in formula (1). (In the formula, R 1 and/or R 2 represents an alkoxy group, an alkenyloxy group, an alkynyloxy group, an aryloxy group, a heteroaryloxy group or an alkyl group that includes at least one ether structure, R 3 and R 4 represent a prescribed substituent, n 1 and n 2 are integers 0-3, and Ar 1 and Ar 2 represent a prescribed nitrogen-containing group.)

5. 发明公开

EP1947101A1 HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR 审中-公开
标题翻译： HYDRAZIDE化合物和血小板生成素受体激活剂
公开(公告)号：EP1947101A1
公开(公告)日：2008-07-23
申请号：EP06823097.8
申请日：2006-11-07
申请人： Nissan Chemical Industries, Ltd.
发明人： MIYAJI, Katsuaki , SHIGETA, Yukihiro , NAKANO, Satoshi , OTA, Hirofumi , ISHIWATA, Norihisa
IPC分类号： C07D409/12 , A61K31/4155 , A61K31/4439 , A61K31/454 , A61K31/5377 , A61P7/00 , A61P9/00 , A61P9/10 , A61P43/00 , C07D409/14
CPC分类号： C07D409/12 , C07D409/14
摘要： Compounds effective for preventing, treatment or improving diseases against which activation of the thrombopoietin receptor is effective are provided.
A compound represented by the formula (I) (wherein R 1 , R 2 , R 3 , L 1 , L 2 , X and Y are defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.
摘要翻译：提供了有效预防，治疗或改善血小板生成素受体活化有效的疾病的化合物。由式（I）表示的化合物（其中R 1，R 2，R 3，L 1，L 2，X和Y在说明书中定义），该化合物的互变异构体，前药或药学上可接受的盐或其溶剂化物。

6. 发明公开

EP1819692A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS 审中-公开
标题翻译： 3- ETHYLIDENHYDRAZINO-取代的杂环化合物作为资产THROMBOPOIETINREZEPTORS的栅极
公开(公告)号：EP1819692A1
公开(公告)日：2007-08-22
申请号：EP05816744.6
申请日：2005-12-07
申请人： Nissan Chemical Industries, Ltd.
发明人： MIYAJI, Katsuaki , SHIGETA, Yukihiro , NAKANO, Satoshi , IWAMOTO, Shunsuke , HIROKAWA, Yutaka , OTA, Hirofumi , YANAGIHARA, Kazufumi , OWADA, Shingo , ISHIWATA, Norihisa Nissan Chemical Ind., Ltd.
IPC分类号： C07D333/32 , C07D231/18 , A61K31/415 , A61P7/00
CPC分类号： C07D409/12 , C07D333/32 , C07D401/12
摘要： A compound represented by the formula (1): wherein A, B, R1, L1, R2, L2, L3, Y, L4, R3 and X are the same as defined in the description, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.

7. 发明授权

EP2921489B1 2-PYRIDONE COMPOUND 有权
标题翻译： 2-吡啶酮化合物
公开(公告)号：EP2921489B1
公开(公告)日：2017-09-06
申请号：EP13855534.7
申请日：2013-11-12
申请人： Nissan Chemical Industries, Ltd.
发明人： KURODA, Shoichi , IMAI, Yudai , KAWAGUCHI, Takanori , FUSEGI, Keiko , BOHNO, Masahiro , ASANUMA, Hajime , CHONAN, Tomomichi , SATO, Nagaaki , MONMA, Souichi , SASAKO, Shigetada , MIZUTANI, Marie , ITOH, Shin , OKADA, Takumi , OTA, Hirofumi , ISHIYAMA, Seishi
IPC分类号： C07D401/06 , A61K31/4439 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P13/12 , A61P27/02 , A61P43/00
CPC分类号： C07D401/06 , A61K31/4439

8. 发明公开

EP3124468A1 FLUORENE DERIVATIVE AND USE THEREOF 审中-公开
标题翻译： FLUORENDERIVAT UND VERWENDUNG DAVON
公开(公告)号：EP3124468A1
公开(公告)日：2017-02-01
申请号：EP15770297.8
申请日：2015-03-23
申请人： Nissan Chemical Industries, Ltd.
发明人： OTA, Hirofumi , ENDO, Toshiyuki
IPC分类号： C07C217/76 , C07C213/08 , C09K11/06 , H01L51/50 , C07B61/00
CPC分类号： H01L51/006 , C07C209/68 , C07C211/54 , C07C213/08 , C07C217/76 , C07C2103/18 , C07C2603/18 , C09D5/22 , C09D5/24 , H01L51/0052 , H01L51/5056 , H01L51/506 , H01L51/5076 , H01L51/5088
摘要： Provided is the fluorene derivative represented in formula (1).

(In the formula, R 1 and/or R 2 represents an alkoxy group, an alkenyloxy group, an alkynyloxy group, an aryloxy group, a heteroaryloxy group or an alkyl group that includes at least one ether structure, R 3 and R 4 represent a prescribed substituent, n 1 and n 2 are integers 0-3, and Ar 1 and Ar 2 represent a prescribed nitrogen-containing group.)
摘要翻译：提供式（1）表示的芴衍生物。（式中，R 1和/或R 2表示烷氧基，烯氧基，炔氧基，芳氧基，杂芳氧基或含有至少一个醚结构的烷基，R 3和R 4表示规定的取代基，n 1和n 2为0〜3的整数，Ar 1和Ar 2表示规定的含氮基团。

9. 发明公开

EP3168250A1 FLUORINE-ATOM-CONTAINING POLYMER AND USE THEREOF 审中-公开
标题翻译：氟维生素D聚合物维生素DAVON
公开(公告)号：EP3168250A1
公开(公告)日：2017-05-17
申请号：EP15818213.9
申请日：2015-07-10
申请人： Nissan Chemical Industries, Ltd.
发明人： OTANI, Naoki , OTA, Hirofumi
IPC分类号： C08G61/12 , C07C211/56 , H01L51/46 , H01L51/50 , H05B33/10
摘要： Provided are a fluorine-atom-containing polymer that is a condensation polymer of a fluorine-atom-containing triphenylamine derivative giving a repeating unit represented by formula (1) and a fluorene derivative giving a repeating unit represented by formula (2) and the use of this fluorine-atom-containing polymer.

(In the formulas, A represents a fluoroalkanediyl group, at least one of R 1 and R 2 represents any of an alkoxyl group, an alkenyloxy group, an alkynyloxy group, an aryloxy group, a heteroaryloxy group, and an alkyl group including at least one ether structure, R 3 -R 6 represent prescribed substituents, m 1 and m 2 each independently represent an integer of 0-4, n 1 and n 2 represent an integer of 0-3.)
摘要翻译：本发明提供含有氟原子的聚合物，其为含有式（1）表示的重复单元的含氟原子的三苯胺衍生物和赋予式（2）表示的重复单元的芴衍生物和使用的含氟原子的聚合物。（式中，A表示氟烷撑基，R 1和R 2中的至少一个表示烷氧基，烯氧基，炔氧基，芳氧基，杂芳氧基，烷基，一个醚结构，R 3 -R 6表示规定的取代基，m 1和m 2各自独立地表示0-4的整数，n 1和n 2表示0-3的整数。）

10. 发明公开

EP1904472A1 THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS 审中-公开
标题翻译：噻吩连接和血小板生成素受体激活剂
公开(公告)号：EP1904472A1
公开(公告)日：2008-04-02
申请号：EP06781284.2
申请日：2006-07-13
申请人： Nissan Chemical Industries, Ltd.
发明人： MIYAJI, Katsuaki , YANAGIHARA, Kazufumi , SHIGETA, Yukihiro , IWAMOTO, Shunsuke , HORIKAWA, Masato , HIROKAWA, Yutaka , OWADA, Shingo , NAKANO, Satoshi , OTA, Hirofumi , ISHIWATA, Norihisa
IPC分类号： C07D333/32 , C07D409/12
CPC分类号： C07D409/14 , C07D333/32 , C07D333/38 , C07D413/14
摘要： ABSTRACT A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.

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