专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20140286978A1 CYTOTOXIC T LYMPHOCYTE INDUCER 审中-公开
标题翻译： CYTOTOXIC T淋巴细胞诱导因子
公开(公告)号：US20140286978A1
公开(公告)日：2014-09-25
申请号：US14117575
申请日：2012-04-24
申请人： TOKYO INSTITUTE OF TECHNOLOGY , LSIP, LLC , SAITAMA MEDICAL UNIVERSITY
发明人： Hiroshi Handa , Masaaki Kawano , Masanori Matsui
IPC分类号： A61K39/145 , A61K39/00
CPC分类号： A61K39/145 , A61K35/76 , A61K38/162 , A61K39/0011 , A61K39/12 , A61K2039/5258 , A61K2039/55561 , C12N2710/22023 , C12N2710/22034 , C12N2760/16134
摘要： The invention provides a cytotoxic T lymphocyte inducer comprising a virus-like particle composed of VP1 of simian virus 40. The T cell epitope peptide is inserted into a DE loop and/or an HI loop of the VP1.
摘要翻译：本发明提供了包含由猿猴病毒40的VP1组成的病毒样颗粒的细胞毒性T淋巴细胞诱导剂.T细胞表位肽插入到VP1的DE环和/或HI环中。

2. 发明授权

US10369218B2 Immunostimulator and method for producing the same 有权
公开(公告)号：US10369218B2
公开(公告)日：2019-08-06
申请号：US15387951
申请日：2016-12-22
申请人： Saitama Medical University , SYSMEX CORPORATION
发明人： Hiroshi Handa , Masaaki Kawano , Masahiko Kato
IPC分类号： A61K39/00 , A61K39/39
摘要： Disclosed is an immunostimulator containing virus-like particles, in which the virus-like particles contain an outer coat protein containing an amino acid sequence selected from the group consisting of SEQ ID No. 1, SEQ ID No. 26, SEQ ID No. 33, SEQ ID No. 35, SEQ ID No. 37, SEQ ID No. 39, SEQ ID No. 41, SEQ ID No. 43 and SEQ ID No. 45; the outer coat protein constitutes an outer coat of the virus-like particles; and the virus-like particles do not substantially contain a genome DNA of SV40.

3. 发明授权

US10994007B2 Immunity inducer 有权
公开(公告)号：US10994007B2
公开(公告)日：2021-05-04
申请号：US15363748
申请日：2016-11-29
申请人： Hiroshi Handa , Saitama Medical University , SYSMEX CORPORATION
发明人： Hiroshi Handa , Masaaki Kawano , Masahiko Kato
IPC分类号： A61K39/12 , A61K39/39 , C12N7/00 , C07K14/005 , A61K39/00
摘要： Disclosed is an immunity inducer. The immunity inducer comprises virus like particles; the virus like particles comprise a virus-derived outer coat protein and an antigen-bound protein comprising an exogenous antigen; the outer coat protein constitutes an outer coat of the virus like particles, and the antigen-bound protein is comprised in the outer coat; and the virus like particles induce an immune effect of a living body on the antigen.

4. 发明申请

US20150125941A1 DETECTION SYSTEM OF TEST SUBSTANCE 有权
标题翻译：检测物质检测系统
公开(公告)号：US20150125941A1
公开(公告)日：2015-05-07
申请号：US14589492
申请日：2015-01-05
申请人： TOPPAN PRINTING CO., LTD. , TOKYO INSTITUTE OF TECHNOLOGY
发明人： Takumi HIRASE , Masato Nakayama , Hiroshi Handa , Satoshi Sakamoto , Yasuyuki Naito
IPC分类号： G01N33/543 , G01N21/64
CPC分类号： G01N33/54326 , G01N21/6428 , G01N21/645
摘要： A detection system of a test substance, includes: a magnetic body that is modified by a first substance capable of being bound to the test substance at a first binding site of the test substance; a marker that is modified by a second substance capable of being bound to the test substance at a second binding site of the test substance, the second coupling site being a different site from the first binding site; a development medium that has a flow passage into which liquid, in which the magnetic body and the marker is dispersed, flows due to a capillary phenomenon, the development medium having a detection position for detecting the marker in a portion of the flow passage, the development medium having light transparency at least in the detection position; and a magnetic force generating portion that is equipped in the development medium.
摘要翻译：测试物质的检测系统包括：被测物质的第一结合位点被能够与被检物质结合的第一物质改性的磁性体; 能够在被检物质的第二结合位点与被检物质结合的第二物质修饰的标记，第二偶联位点是与第一结合位点不同的位点; 具有流路的开发介质，由于毛细管现象，磁性体和标记物分散在其中的液体流动，显影介质具有用于检测流路的一部分中的标记的检测位置，至少在检测位置具有透光性的显影介质; 以及设置在显影介质中的磁力产生部。

5. 发明授权

US09632077B2 Detection system of test substance 有权
公开(公告)号：US09632077B2
公开(公告)日：2017-04-25
申请号：US14589492
申请日：2015-01-05
申请人： TOPPAN PRINTING CO., LTD. , TOKYO INSTITUTE OF TECHNOLOGY
发明人： Takumi Hirase , Masato Nakayama , Hiroshi Handa , Satoshi Sakamoto , Yasuyuki Naito
IPC分类号： G01N33/543 , G01N21/64
CPC分类号： G01N33/54326 , G01N21/6428 , G01N21/645
摘要： A detection system of a test substance, includes: a magnetic body that is modified by a first substance capable of being bound to the test substance at a first binding site of the test substance; a marker that is modified by a second substance capable of being bound to the test substance at a second binding site of the test substance, the second coupling site being a different site from the first binding site; a development medium that has a flow passage into which liquid, in which the magnetic body and the marker is dispersed, flows due to a capillary phenomenon, the development medium having a detection position for detecting the marker in a portion of the flow passage, the development medium having light transparency at least in the detection position; and a magnetic force generating portion that is equipped in the development medium.

6. 发明申请

US20150147812A1 CARRIER FOR GENE INTRODUCTION USE, GENE INTRODUCTION AGENT, METHODS FOR PRODUCING SAID CARRIER AND SAID GENE INTRODUCTION AGENT, AND METHOD FOR INTRODUCING GENE INTO CELL 审中-公开
标题翻译：基因引入用载体，基因引物代理，生产载体和鉴定基因引物的方法以及将基因引入细胞的方法
公开(公告)号：US20150147812A1
公开(公告)日：2015-05-28
申请号：US14403957
申请日：2013-05-30
申请人： LSIP, LLC
发明人： Hiroshi Onodera , Hiroshi Handa , Satoshi Sakamoto , Mamoru Hatakeyama
IPC分类号： C12N15/90
CPC分类号： C12N15/907 , A61K9/0019 , A61K9/0085 , A61K9/009 , A61K47/6901 , A61K47/6929 , C12N15/87
摘要： The present invention provides; a novel gene introduction method which enables a gene to be introduced more safely and more freely, particularly a method for introducing a gene into a specified site in the brain safely and freely; a carrier for gene introduction use, which comprises a nano-particle and a substance capable of binding to a vector for gene introduction and has functional groups involved in the induction of phagocytosis by cells, wherein the substance capable of binding to a vector for gene introduction can bind to the surface of the nano-particle through some of the functional groups and another some of the functional groups remain unbound to the substance capable of binding to a vector for gene introduction; and a gene introduction agent, in which a vector for gene introduction is bound to the substance capable of binding to a vector for gene introduction in the carrier for gene introduction.
摘要翻译：本发明提供：特别是将基因安全自由地引入脑内指定部位的方法，能够使基因更安全，更自由地引入的新型基因导入方法。用于基因导入的载体，其包含纳米颗粒和能够结合用于基因导入的载体的物质，并且具有参与通过细胞诱导吞噬作用的官能团，其中所述能够结合用于基因导入的载体的物质可以通过一些官能团与纳米颗粒的表面结合，另一些官能团保持未结合到能够与基因导入载体结合的物质; 以及基因导入剂，其中用于基因导入的载体与能够结合到用于基因导入的载体中的基因导入载体结合的物质结合。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式