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1. 发明申请

US20060228799A1 Use of consensus sequences for targeted homologous gene isolation and recombination in gene families 审中-公开
公开(公告)号：US20060228799A1
公开(公告)日：2006-10-12
申请号：US11244325
申请日：2005-10-05
申请人： Sushma Pati , David Zarling , Christopher Lehman , Hong Zeng
发明人： Sushma Pati , David Zarling , Christopher Lehman , Hong Zeng
IPC分类号： C12N15/86 , C12N15/74
CPC分类号： C12N15/1093 , C12N15/902
摘要： The invention relates to compositions and methods for targeting sequence modifications in one or more genes of a related family of genes using enhanced homologous recombination techniques. These techniques may be used to create animal or plant models of disease as well as to identify new targets for drug or pathogen screening.

2. 发明授权

US06524856B1 Use of consensus sequences for targeted homologous gene isolation and recombination in gene families 失效
标题翻译：在基因家族中使用共有序列进行靶向同源基因分离和重组
公开(公告)号：US06524856B1
公开(公告)日：2003-02-25
申请号：US09209676
申请日：1998-12-11
申请人： Sushma Pati , David A. Zarling , Hong Zeng
发明人： Sushma Pati , David A. Zarling , Hong Zeng
IPC分类号： C12N1563
CPC分类号： C12N15/1082 , A01K2217/05 , A61K48/00 , C12N15/1034 , C12N15/902 , C12Q1/6811
摘要： The invention relates to compositions and methods for targeting sequence modifications in one or more genes of a related family of genes using enhanced homologous recombination techniques. These techniques may be used to create animal or plant models of disease as well as to identify new targets for drug or pathogen screening.
摘要翻译：本发明涉及使用增强的同源重组技术靶向相关基因家族的一个或多个基因中的序列修饰的组合物和方法。这些技术可用于创建疾病的动物或植物模型，以及确定用于药物或病原体筛选的新靶标。

3. 发明申请

US20110235993A1 AUDIO-BASED CHAPTER DETECTION IN MULTIMEDIA STREAM 有权
标题翻译：基于音频的多媒体流检测
公开(公告)号：US20110235993A1
公开(公告)日：2011-09-29
申请号：US12729378
申请日：2010-03-23
申请人： Hong Zeng
发明人： Hong Zeng
IPC分类号： H04N5/91 , H04N9/80
CPC分类号： G11B27/28
摘要： A multimedia processing system identifies chapter breaks in a program represented by multimedia data through an analysis of audio content of a portion of the multimedia data so as to identify an interval that potentially represents a chapter break. This audio analysis can include an analysis to identify changes in high frequency edges in the audio content, an analysis to identify changes in the total energy in a central frequency band of the audio content, an analysis to identify patterns of sequentially repeating values in the audio content, an analysis to identify changes in bitrate, or some combination thereof. One or more variances in the audio information at (e.g., before) the start of the interval and the audio information at (e.g., after) the end of the interval then may be used to identify or otherwise characterize the interval as representing an actual chapter break. Further, a chapter represented by two consecutive chapter breaks can be identified as an advertisement based on the duration between the two consecutive chapter breaks and thus the multimedia processing device can implement a “commercial skip function” by omitting playback of the portion of the multimedia data representing the chapter responsive to the chapter being identified as an advertisement.
摘要翻译：多媒体处理系统通过对多媒体数据的一部分的音频内容的分析来识别由多媒体数据表示的节目中的章节断开，以便识别潜在地代表分章的间隔。该音频分析可以包括用于识别音频内容中的高频边缘的变化的分析，用于识别音频内容的中心频带中的总能量的变化的分析，识别音频中顺序重复值的模式的分析内容，识别比特率变化的分析，或其某些组合。间隔开始时（例如，之前）和间隔结束处（例如，之后）的音频信息中的音频信息中的一个或多个方差可以用于识别或以其他方式表征间隔，以表示实际章节打破。此外，由两个连续的分节符表示的章节可以基于两个连续的章节间隔之间的持续时间被识别为广告，因此多媒体处理设备可以通过省略多媒体数据的一部分的重放来实现“商业跳过功能” 代表响应该章被确定为广告的章节。

4. 发明授权

US09124233B2 Audio equalizer and methods for use therewith 有权
标题翻译：音频均衡器及其使用方法
公开(公告)号：US09124233B2
公开(公告)日：2015-09-01
申请号：US12868617
申请日：2010-08-25
申请人： Hong Zeng
发明人： Hong Zeng
IPC分类号： H03G5/00 , H03G9/02 , H03G9/00
CPC分类号： H03G9/025 , H03G9/005
摘要： An audio equalizer includes an equalization processor that operates in conjunction with a transformed-based audio decoder that generates a decoded audio signal from an encoded audio signal. The equalization processor receives an equalization input signal, generates a plurality of response coefficients in response to the equalization input and applies the response coefficients to partially decoded data of the transformed-based audio decoder.
摘要翻译：音频均衡器包括均衡处理器，其与基于变换的音频解码器相结合，该解码器从已编码的音频信号产生解码的音频信号。均衡处理器接收均衡输入信号，响应于均衡输入产生多个响应系数，并将响应系数应用于基于变换的音频解码器的部分解码数据。

5. 发明授权

US08812390B1 System and method for an implied alpha model and investor preferences 有权
标题翻译：隐含的α模型和投资者偏好的系统和方法
公开(公告)号：US08812390B1
公开(公告)日：2014-08-19
申请号：US13537371
申请日：2012-06-29
申请人： Hong Zeng
发明人： Hong Zeng
IPC分类号： G06Q40/00
CPC分类号： G06Q40/06
摘要： The instant invention relates generally to a group of computer-based methods preferably utilized in an implied alpha model and investor preferences to detect and address a preference drag problem. The computer-based method starts with an implied alpha model, which is derived from an existing portfolio. An implied alpha model can be treated as a preference aggregation when its factors represent investors' preferences on the portfolio. In this case, the model is also called an implied preference model. After an implied preference model is developed from a portfolio, a drag problem can be detected by checking whether the model has persistent and negative returns. If a drag problem exists in a portfolio, it can be solved by modifying the portfolio under assistance from the model.
摘要翻译：本发明一般涉及一组基于计算机的方法，优选地以隐含的α模型和投资者偏好来使用，以检测和解决偏好拖曳问题。基于计算机的方法从隐含的α模型开始，该模型来自现有的投资组合。当其因素代表投资者对投资组合的偏好时，隐含的α模型可以被视为偏好汇总。在这种情况下，模型也称为默认偏好模型。在从投资组合开发隐含偏好模型之后，可以通过检查模型是否具有持续回报和负回报来检测拖拽问题。如果投资组合存在拖累问题，可以通过在模型的帮助下修改投资组合来解决。

6. 发明授权

US08806450B1 Static analysis in selective software regression testing 有权
标题翻译：选择性软件回归测试中的静态分析
公开(公告)号：US08806450B1
公开(公告)日：2014-08-12
申请号：US12146690
申请日：2008-06-26
申请人： Srinibas Maharana , Manu J. Prakash , Hong Zeng , Sachin Vasudeva , Tao Deng
发明人： Srinibas Maharana , Manu J. Prakash , Hong Zeng , Sachin Vasudeva , Tao Deng
IPC分类号： G06F9/44
CPC分类号： G06F11/3688 , G06F8/71 , G06F8/75 , G06F11/3608
摘要： Static analysis of software code may be performed in a selective regression testing framework. The static impact analysis, when carried out in a comprehensive and efficient way, can help make the test selection safer and more complete. One method for performing static analysis in selective regression testing of a software project includes, for example, storing changes to source code that defines functions and global data elements of the software project; performing a static analysis of the source code to determine which global data elements in the source code correspond to changed functions in the source code and executing a regression test of the software project using a set of test units determined based, at least in part, on the static analysis.
摘要翻译：可以在选择性回归测试框架中执行软件代码的静态分析。静态影响分析以全面有效的方式进行，可以帮助测试选择更安全，更完整。在软件项目的选择性回归测试中执行静态分析的一种方法包括例如存储对定义软件项目的功能和全局数据元素的源代码的改变; 执行源代码的静态分析以确定源代码中的哪些全局数据元素对应于源代码中的改变的函数，并且使用一组测试单元执行软件项目的回归测试，所述测试单元至少部分地基于静态分析。

7. 发明授权

US07739105B2 System and method for processing audio frames 有权
标题翻译：用于处理音频帧的系统和方法
公开(公告)号：US07739105B2
公开(公告)日：2010-06-15
申请号：US10461095
申请日：2003-06-13
申请人： Hong Zeng
发明人： Hong Zeng
IPC分类号： G10L11/00 , G10L21/02 , G10L19/00
CPC分类号： G10L19/02
摘要： In accordance with a specific implementation of the disclosure, a stream of audio frames is received and compressed using psycho-acoustical processing. The signal-to-mask ratio table generated by the psycho-acoustical algorithm is updated using only a portion of the received audio frames.
摘要翻译：根据本公开的具体实现，使用心理声学处理来接收和压缩音频帧流。由心理声学算法产生的信号与掩模比表仅使用所接收的音频帧的一部分进行更新。

8. 发明授权

US08422859B2 Audio-based chapter detection in multimedia stream 有权
标题翻译：多媒体流中基于音频的章检测
公开(公告)号：US08422859B2
公开(公告)日：2013-04-16
申请号：US12729378
申请日：2010-03-23
申请人： Hong Zeng
发明人： Hong Zeng
IPC分类号： H04N9/80
CPC分类号： G11B27/28
摘要： A multimedia processing system identifies chapter breaks in a program represented by multimedia data through an analysis of audio content of a portion of the multimedia data so as to identify an interval that potentially represents a chapter break. This audio analysis can include an analysis to identify changes in high frequency edges in the audio content, an analysis to identify changes in the total energy in a central frequency band of the audio content, an analysis to identify patterns of sequentially repeating values in the audio content, an analysis to identify changes in bitrate, or some combination thereof. One or more variances in the audio information at (e.g., before) the start of the interval and the audio information at (e.g., after) the end of the interval then may be used to identify or otherwise characterize the interval as representing an actual chapter break. Further, a chapter represented by two consecutive chapter breaks can be identified as an advertisement based on the duration between the two consecutive chapter breaks and thus the multimedia processing device can implement a “commercial skip function” by omitting playback of the portion of the multimedia data representing the chapter responsive to the chapter being identified as an advertisement.
摘要翻译：多媒体处理系统通过对多媒体数据的一部分的音频内容的分析来识别由多媒体数据表示的节目中的章节断开，以便识别潜在地代表分章的间隔。该音频分析可以包括用于识别音频内容中的高频边缘的变化的分析，用于识别音频内容的中心频带中的总能量的变化的分析，识别音频中顺序重复值的模式的分析内容，识别比特率变化的分析，或其某些组合。间隔开始时（例如，之前）和间隔结束处（例如，之后）的音频信息中的音频信息中的一个或多个方差可用于识别或以其他方式表征间隔，以表示实际章节打破。此外，由两个连续的章节断开表示的章节可以基于两个连续的章节间隔之间的持续时间被识别为广告，并且因此多媒体处理设备可以通过省略表示多媒体数据的多媒体数据的一部分的重放来实现商业跳过功能一章响应本章被确定为广告。

9. 发明授权

US06576759B2 Antisense inhibition of RAD51 失效
标题翻译： RAD51的反义抑制
公开(公告)号：US06576759B2
公开(公告)日：2003-06-10
申请号：US09454495
申请日：1999-12-06
申请人： Hong Zeng , Gurucharan Reddy , Anne Vallerga , David A. Zarling
发明人： Hong Zeng , Gurucharan Reddy , Anne Vallerga , David A. Zarling
IPC分类号： C07H2104
CPC分类号： C12N15/113 , A61K31/40 , A61K31/4184 , A61K31/7084 , A61K31/7088 , A61K38/00 , C07K14/47 , C07K16/18 , C12N2310/315
摘要： Provided herein are methods for inhibiting cell proliferation in an individual comprising administering to the individual a composition comprising a Rad51 inhibitor. Also provided herein is a method for inhibiting the growth of a cell comprising administering to said cell a composition comprising a Rad51 inhibitor. Such methods can further include the step of providing radiation or DNA damaging agents after administration of said Rad51 inhibitor. Also described herein are methods which are performed in vivo and/or on cancerous cells.
摘要翻译：本文提供了抑制个体中细胞增殖的方法，包括向个体施用包含Rad51抑制剂的组合物。本文还提供了抑制细胞生长的方法，包括向所述细胞施用包含Rad51抑制剂的组合物。这种方法还可以包括在施用所述Rad51抑制剂之后提供辐射或DNA损伤剂的步骤。本文还描述了在体内和/或癌细胞上进行的方法。

10. 发明授权

US06432901B1 Bleach catalysts 有权
公开(公告)号：US06432901B1
公开(公告)日：2002-08-13
申请号：US09740122
申请日：2000-12-19
申请人： Dai Cong-Yun , Dao-Li Deng , Ronald Hage , Chang-Qing Ye , Hong Zeng
发明人： Dai Cong-Yun , Dao-Li Deng , Ronald Hage , Chang-Qing Ye , Hong Zeng
IPC分类号： C11D320
摘要： A bleach catalyst system comprising in combination, a macrocyclic organic ligand of formula (I): wherein R1 and R2 can each independently be absent, H, alkyl or aryl, optionally substituted; t and t′ are each independent integers from 2-3; each D can independently be N, NR3, PR3, O or S, wherein each R3 is independently H, alkyl or aryl, optionally substituted by one or more suitable substituents such as C1-4 alkyl groups, or is a bridging group such as C1-6 alkylene, either to another R3 group in the same macrocycle or to another independently defined macrocycle or to another independently defined macrocyclic ligand of formula (I), wherein any bridging group optionally contains an optionally substituted heteroatom such as nitrogen; and s is an integer from 2-5; and a water-insoluble manganese compound.

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