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1. 发明授权

US07125407B2 Sphincter treatment apparatus 失效
标题翻译：括约肌治疗仪
公开(公告)号：US07125407B2
公开(公告)日：2006-10-24
申请号：US10728684
申请日：2003-12-05
申请人： Stuart D Edwards , John W. Gaiser , David S. Utley , Jay J. Qin
发明人： Stuart D Edwards , John W. Gaiser , David S. Utley , Jay J. Qin
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B17/32 , A61B18/1206 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/22061 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0438 , A61M16/0481 , A61M25/1002 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40
摘要： A sphincter treatment apparatus includes an elongated member having at least one lumen including an inflation lumen and a basket assembly with first and second arms. The basket assembly is coupled to the elongated member and has deployed and non-deployed configurations. An inflatable member is coupled to the elongated member and positioned in an interior of the basket assembly. The inflatable member has deployed and non-deployed states and is coupled to the inflation lumen. In the deployed state, the inflatable member expands the basket assembly to its deployed configuration. A first energy delivery device is positionable in the first arm and advanceable from the first arm to a selected treatment site. A second energy delivery device is positionable in the second arm and advanceable from the second arm to a selected treatment site.
摘要翻译：括约肌治疗装置包括细长构件，其具有包括充气腔的至少一个内腔和具有第一和第二臂的篮组件。筐组件联接到细长构件并且具有展开和非展开构造。可膨胀构件联接到细长构件并且定位在篮组件的内部。充气构件具有展开状态和非展开状态，并且连接到膨胀腔。在展开状态下，可膨胀构件将篮组件膨胀到其展开构型。第一能量输送装置可定位在第一臂中并且可从第一臂推进到选定的处理部位。第二能量输送装置可定位在第二臂中并且可从第二臂推进到选定的治疗部位。

2. 发明授权

US07632268B2 System for tissue ablation 失效
标题翻译：组织消融系统
公开(公告)号：US07632268B2
公开(公告)日：2009-12-15
申请号：US11420712
申请日：2006-05-26
申请人： Stuart D Edwards , John Gaiser , David S Utley , Scott H West , Jay Qin
发明人： Stuart D Edwards , John Gaiser , David S Utley , Scott H West , Jay Qin
IPC分类号： A61B18/18 , A61F2/00
CPC分类号： A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Systems for treating a mucosal surface of an alimentary canal tissue region are provided. The systems can include an elongate support structure, an expandable member positionable at a distal portion of the support structure and one or more radio frequency (RF) ablation electrodes carried by the expandable member. The elongate support structure and the expandable member can be adapted to place the one or more electrodes in contact with a mucosal surface of an alimentary canal tissue region. The system can further include an RF energy source connected to the one or more electrodes.
摘要翻译：提供了用于治疗消化道组织区域的粘膜表面的系统。该系统可以包括细长的支撑结构，可定位在支撑结构的远端部分处的可扩张构件以及由可扩张构件承载的一个或多个射频（RF）消融电极。细长支撑结构和可扩张构件可适于将一个或多个电极与消化道组织区域的粘膜表面接触。该系统还可以包括连接到一个或多个电极的RF能量源。

3. 发明授权

US06866663B2 Method for treating a sphincter 失效
公开(公告)号：US06866663B2
公开(公告)日：2005-03-15
申请号：US10254471
申请日：2002-09-25
申请人： Stuart D Edwards , David S Utley , Ronald G Lax , John Gaiser
发明人： Stuart D Edwards , David S Utley , Ronald G Lax , John Gaiser
IPC分类号： A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B18/18 , A61B2018/00011 , A61B2018/00029 , A61B2018/00047 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00553 , A61B2018/00666 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2218/002
摘要： A method for treating a sphincter provides a polymer material having a liquid state. The method also provides a catheter having a distal end, a tissue piercing device carried by the distal end, and an energy delivery device coupled to the tissue piercing device. The tissue piercing device has a lumen. The method introduces the catheter into an esophagus and pierces an exterior sphincter tissue surface within with the tissue piercing device. The method advances the tissue piercing device into an interior sphincter tissue site and conveys the polymer material while in a liquid state through the lumen into the interior sphincter tissue site. The method delivers energy to the tissue piercing device to transform the polymer material into a less liquid state within the interior sphincter tissue site, to thereby remodel the sphincter.

4. 发明授权

US06749607B2 Apparatus to treat esophageal sphincters 有权
标题翻译：食管括约肌治疗仪
公开(公告)号：US06749607B2
公开(公告)日：2004-06-15
申请号：US09971085
申请日：2001-10-04
申请人： Stuart D Edwards , David S Utley
发明人： Stuart D Edwards , David S Utley
IPC分类号： A61B1818
CPC分类号： A61B18/1477 , A61B5/4233 , A61B18/0218 , A61B18/1492 , A61B2017/3445 , A61B2017/345 , A61B2018/00267 , A61B2018/00488 , A61B2018/00553 , A61B2018/00589 , A61B2018/00648 , A61B2018/00702 , A61B2018/00821 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00994 , A61B2018/0262 , A61B2018/0293 , A61B2018/046 , A61B2018/1861 , A61B2018/1869
摘要： A sphincter treatment apparatus has an introducer means including a distal portion means. An expandable device means includes a plurality of arm means. Each arm means of the plurality has a distal section means and a proximal section means. Each of distal sections means of the arm means are coupled and each of the proximal sections means of the arm means are coupled to the introducer means distal portion means. The expandable device means is configured to at least partially dilate a sphincter in a deployed state. An energy delivery device means is introduceable from the introducer means into a selected site of the sphincter. The energy delivery device means is configured to deliver sufficient energy to reduce a frequency of relaxation of the sphincter.
摘要翻译：括约肌治疗装置具有包括远端部分装置的导引装置。可扩张装置包括多个臂装置。多个臂的每个臂装置具有远端部分装置和近端部分装置。臂装置的每个远端部分装置联接，并且臂装置的每个近端部分装置联接到导引装置远端部分装置。可扩张装置装置构造成在展开状态下至少部分地扩张括约肌。能量输送装置装置可从导引器装置引入括约肌的选定部位。能量递送装置装置被配置为递送足够的能量以减少括约肌的松弛频率。

5. 发明授权

US06589238B2 Sphincter treatment device 失效
标题翻译：括约肌治疗装置
公开(公告)号：US06589238B2
公开(公告)日：2003-07-08
申请号：US10084590
申请日：2002-02-27
申请人： Stuart D Edwards , David S Utley
发明人： Stuart D Edwards , David S Utley
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/00553
摘要： An apparatus includes a first expandable member that is expandable by an expansion medium. The first expandable member includes an exterior and a plurality of apertures. The expansion medium is released from the first expandable member when a sufficient pressure is applied to the expansion medium housed in an interior of the first expandable member. A second expandable member is positioned at least partially adjacent to the first expandable member. The second expandable member is configured to receive at least a portion of the expansion medium from the interior of the first expandable member. An electromagnetic energy delivery device is coupled to one of the first or second expandable members and is configured to be coupled to a power source. The first and second expandable members are sized to be expanded sufficiently to open a sphincter.
摘要翻译：一种装置包括可由膨胀介质膨胀的第一可膨胀构件。第一可扩展构件包括外部和多个孔。当向容纳在第一可扩展构件的内部的膨胀介质施加足够的压力时，膨胀介质从第一可膨胀构件释放。第二可膨胀构件被定位成至少部分地邻近第一可膨胀构件。第二可膨胀构件构造成从第一可膨胀构件的内部接收膨胀介质的至少一部分。电磁能量传递装置耦合到第一或第二可扩展构件中的一个，并且被配置为联接到电源。第一和第二可扩张构件的尺寸设计成足够扩张以打开括约肌。

6. 发明授权

US06254598B1 Sphincter treatment apparatus 有权
标题翻译：括约肌治疗仪
公开(公告)号：US06254598B1
公开(公告)日：2001-07-03
申请号：US09235060
申请日：1999-01-20
申请人： Stuart D Edwards , John W. Gaiser , David S. Utley , Jay J. Qin
发明人： Stuart D Edwards , John W. Gaiser , David S. Utley , Jay J. Qin
IPC分类号： A61B1818
CPC分类号： A61B18/1477 , A61B17/32 , A61B18/1206 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00084 , A61B2017/00106 , A61B2017/003 , A61B2017/22061 , A61B2017/4216 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00065 , A61B2018/00077 , A61B2018/00083 , A61B2018/00113 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00886 , A61B2018/00892 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/00982 , A61B2018/0262 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61M3/0279 , A61M16/0438 , A61M16/0481 , A61M25/1002 , A61M2025/1052 , A61M2025/1086 , A61N1/056 , A61N1/06 , A61N1/08 , A61N1/40
摘要： A sphincter treatment apparatus includes an elongated member having at least one lumen including an inflation lumen and a basket assembly with first and second arms. The basket assembly is coupled to the elongated member and has deployed and non-deployed configurations. An inflatable member is coupled to the elongated member and positioned in an interior of the basket assembly. The inflatable member has deployed and non-deployed states and is coupled to the inflation lumen. In the deployed state, the inflatable member expands the basket assembly to its deployed configuration. A first energy delivery device is positionable in the first arm and advanceable from the first arm to a selected treatment site. A second energy delivery device is positionable in the second arm and advanceable from the second arm to a selected treatment site.
摘要翻译：括约肌治疗装置包括细长构件，其具有包括充气腔的至少一个内腔和具有第一和第二臂的篮组件。筐组件联接到细长构件并且具有展开和非展开构造。可膨胀构件联接到细长构件并且定位在篮组件的内部。充气构件具有展开状态和非展开状态，并且连接到膨胀腔。在展开状态下，可膨胀构件将篮组件膨胀到其展开构型。第一能量输送装置可定位在第一臂中并且可从第一臂推进到选定的处理部位。第二能量输送装置可定位在第二臂中并且可从第二臂推进到选定的治疗部位。

7. 发明授权

US08790339B2 Apparatus to detect and treat aberrant myoelectric activity 有权
标题翻译：检测和治疗异常肌电活动的装置
公开(公告)号：US08790339B2
公开(公告)日：2014-07-29
申请号：US13443503
申请日：2012-04-10
申请人： Stuart D Edwards , David S Utley , Ronald G Lax
发明人： Stuart D Edwards , David S Utley , Ronald G Lax
IPC分类号： A61B18/14
CPC分类号： A61B5/04884 , A61B18/1477 , A61B18/1485 , A61B90/39 , A61B2018/00553 , A61B2018/00738 , A61B2018/046 , A61B2090/3925 , A61B2560/0242
摘要： An apparatus to treat a sphincter has a support member. A sphincter electropotential mapping device includes a mapping electrode. The sphincter electropotential mapping device is coupled to the support member and configured to detect aberrant myoelectric activity of the sphincter.
摘要翻译：治疗括约肌的装置具有支撑构件。括约肌电位映射装置包括映射电极。括约肌电位映射设备耦合到支撑构件并且被配置为检测括约肌的异常肌电活动。

8. 发明授权

US07585296B2 Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 有权
标题翻译：通过检测和消融胃食管神经和受体来治疗胃反流的方法
公开(公告)号：US07585296B2
公开(公告)日：2009-09-08
申请号：US11230801
申请日：2005-09-20
申请人： Stuart D Edwards , John Gaiser , David S Utley
发明人： Stuart D Edwards , John Gaiser , David S Utley
IPC分类号： A61B18/18
CPC分类号： A61B18/1233 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B2017/00039 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00142 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/00898 , A61B2018/0091 , A61B2018/00982 , A61B2018/0237 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2090/064 , A61B2090/3782 , A61B2218/002 , A61N1/06
摘要： A method detects at a tissue site an electrical activity causing a transient relaxation of at least a portion of one of a sphincter, a lower esophageal sphincter, a stomach, a cardia or a fundus. The method treats the electrical activity at the tissue site by delivering electromagnetic energy to ablate at least a portion of one of the nerve, the gastric nerve, a nerve plexus, a myenteric nerve plexus, a ganglia, a nerve pathway or an electrically conductive pathway. The method conducts a cooling solution to the tissue site at a flow rate and adjusts the flow rate in response to sensed temperature conditions.
摘要翻译：一种方法在组织位置处检测导致括约肌，下食道括约肌，胃，贲门或眼底之一的至少一部分的暂时松弛的电活动。该方法通过传递电磁能来消除组织部位的电活动，以消融神经，胃神经，神经丛，肌间神经丛，神经节，神经通路或导电通路中的至少一部分。该方法以流量对组织部位进行冷却溶液，并根据感测的温度条件调节流速。

9. 发明授权

US07122031B2 Graphical user interface for association with an electrode structure deployed in contact with a tissue region 有权
公开(公告)号：US07122031B2
公开(公告)日：2006-10-17
申请号：US10024747
申请日：2001-12-19
申请人： Stuart D Edwards , John W. Gaiser , David S Utley , Scott H. West , Jay Qin
发明人： Stuart D Edwards , John W. Gaiser , David S Utley , Scott H. West , Jay Qin
IPC分类号： A61B18/18
CPC分类号： A61B18/1233 , A61B18/12 , A61B18/1206 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00035 , A61B2018/00077 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00488 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007 , Y10S128/922
摘要： Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

10. 发明授权

US06846312B2 GERD treatment apparatus and method 失效
标题翻译： GERD治疗仪和方法
公开(公告)号：US06846312B2
公开(公告)日：2005-01-25
申请号：US10230655
申请日：2002-08-29
申请人： Stuart D Edwards , David S Utley
发明人： Stuart D Edwards , David S Utley
IPC分类号： A61B17/22 , A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B2017/003 , A61B2017/22061 , A61B2018/00011 , A61B2018/00077 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00553 , A61B2018/00654 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00797 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2018/1472 , A61B2090/3782
摘要： An apparatus to treat a sphincter includes an energy delivery device support member. An energy delivery device is coupled to the energy delivery support member. The energy delivery device has a configuration that controllably produces lesions of a sufficient size and number in the sphincter to create a selectable tightening of the sphincter.
摘要翻译：治疗括约肌的装置包括能量输送装置支撑构件。能量输送装置联接到能量输送支撑构件。能量输送装置具有可控制地产生足够尺寸和数量的括约肌中的损伤以构成括约肌的可选择紧固的构造。

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