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    • 2. 发明申请
    • EXPANDABLE STENT AND METHODS OF CRIMPING AND EXPANDING SUCH STENT
    • 可扩展的支架和压制和扩展这种支架的方法
    • WO2017190161A1
    • 2017-11-02
    • PCT/ZA2017/050025
    • 2017-04-26
    • STRAIT ACCESS TECHNOLOGIES HOLDINGS (PTY) LTD
    • NELSON, Grant LeighPARK, Kenneth StuartVAN BREDA, Braden Sydney CliveBEZUIDENHOUT, DeonZILLA, PeterAPPA, Harish
    • A61F2/24
    • An expandable stent (10) comprises a cylindrical wall made up of lattice members (12) connected to each other, at least one first arm (14) and at least one second arm (15). The first arm comprises: a first non-linear member (16) that is connected at each of its axial ends to a lattice member at respective first junctions; a second non-linear member (18) connected at each axial end to a lattice member; and at least one bridge member (20) extending between the first member and the second member. The second arm comprises: a first non- linear member that is connected at each of its axial ends to a lattice member; a second non-linear member connected at each axial end to a lattice member; and at least one bridge member extending between the first member and the second member. The second member of the first arm is generally U-shaped, extending from its axial ends towards: (i) a first axial end of the stent; and (ii) towards the bridge of the first arm. The second member of the second arm is generally U- shaped, extending from its axial ends towards: (i) a first axial end of the stent; and (ii) towards the bridge of the second arm. The first arm is disposed at a second axial end of the stent, and the second arm is: (i) axially spaced from the first arm towards the first axial end of the stent; and (ii) axially aligned with the first arm. Furthermore, the first member and the second member of each of the first and second arms are connected to lattice members at their axial ends only. Upon radial expansion of the stent from a radially crimped condition under the influence of an external force, tension in: (i) the bridge of the first arm; and (ii) the bridge member of the second arm, causes the second members of both the first and second arms to protrude radially outwards, respectively.
    • 可扩张支架(10)包括由彼此连接的网格构件(12)构成的圆柱形壁,至少一个第一臂(14)和至少一个第二臂(15)。 所述第一臂包括:第一非线性构件(16),所述第一非线性构件(16)在其各自的轴向端处在各自的第一连接处连接至格构件; 第二非线性构件(18),其在每个轴向端处连接至格构件; 和在第一构件和第二构件之间延伸的至少一个桥接构件(20)。 所述第二臂包括:第一非线性构件,其在其每个轴向端处连接至格构件; 第二非线性构件,所述第二非线性构件在每个轴向端连接至格构件; 以及在第一构件和第二构件之间延伸的至少一个桥接构件。 第一臂的第二构件大致为U形,从其轴向端朝向:(i)支架的第一轴向端; 和(ii)朝向第一只手臂的桥梁。 第二臂的第二构件大致为U形,从其轴向端朝向:(i)支架的第一轴向端; 和(ii)朝向第二只手臂的桥梁。 所述第一臂布置在所述支架的第二轴向端部处,并且所述第二臂部:(i)与所述第一臂部朝向所述支架的所述第一轴向端部轴向间隔开; 和(ii)与第一臂轴向对齐。 此外,第一和第二臂中的每一个的第一构件和第二构件仅在其轴向端部处连接到格构件。 在外力的作用下支架从径向卷曲状态径向扩张时,张力在:(i)第一臂的桥; 和(ii)第二臂的桥构件使第一和第二臂的第二构件分别向外径向突出。
    • 3. 发明申请
    • A PROSTHETIC HEART VALVE
    • 一种人造心脏瓣膜
    • WO2014170870A3
    • 2014-10-23
    • PCT/IB2014/060816
    • 2014-04-17
    • STRAIT ACCESS TECHNOLOGIES HOLDINGS (PTY) LTD
    • PARK, Kenneth StuartAPPA, HarishVISAGIE, ClaudeBEZUIDENHOUT, DeonZILLA, Peter Paul
    • A61F2/24
    • A prosthetic heart valve (10) which includes a stent (14) having three leaflets (12) attached thereto is provided. The stent (14) is compressible so as to be capable of being introduced into a patient's body through a minimally invasive procedure and has a ring-like body (16) defining in its height three arch-shaped elements (18). Each element (18) includes an arc (20) and a pair of haunches (22) extending from opposite sides thereof, with three commissural posts (26) formed by the haunches (22) of adjacent elements (18). The leaflets (12) each have an attachment edge (28) and a free edge (30) with a belly (32) extending therebetween. The leaflets (12) are movable between a coapted condition, in which the free edges (30) abut and prevent fluid flow through the valve (10), and an open condition, in which fluid flow through the valve (10) is permitted. The leaflets (12) are made from a polymeric material and are moulded directly onto the stent (14) so as to provide for continuous attachment thereof.
    • 提供了一种假体心脏瓣膜(10),该假体心脏瓣膜(10)包括具有附接到其上的三个小叶(12)的支架(14)。 支架(14)是可压缩的,以便能够通过微创手术引入患者体内并且具有在其高度上限定三个弓形元件(18)的环状主体(16)。 每个元件(18)包括弧(20)和从其相对侧延伸的一对隆起(22),并具有由相邻元件(18)的隆起(22)形成的三个连合柱(26)。 小叶(12)每个都具有附接边缘(28)和自由边缘(30),并具有在其间延伸的腹部(32)。 小叶12可在其中自由边缘30邻接并防止流体流过阀10的合适状态和允许流体流过阀10的打开状态之间移动。 小叶(12)由聚合材料制成并直接模制在支架(14)上以提供其连续附接。
    • 6. 发明公开
    • A PROSTHETIC HEART VALVE
    • 一种人造心脏瓣膜
    • EP2986256A2
    • 2016-02-24
    • EP14745233.8
    • 2014-04-17
    • Strait Access Technologies Holdings (PTY) LTD
    • PARK, Kenneth StuartAPPA, HarishVISAGIE, ClaudeBEZUIDENHOUT, DeonZILLA, Peter Paul
    • A61F2/24
    • A61F2/2418A61F2/2406A61F2/2412A61F2/2415
    • A prosthetic heart valve (10) which includes a stent (14) having three leaflets (12) attached thereto is provided. The stent (14) is compressible so as to be capable of being introduced into a patient's body through a minimally invasive procedure and has a ring-like body (16) defining in its height three arch-shaped elements (18). Each element (18) includes an arc (20) and a pair of haunches (22) extending from opposite sides thereof, with three commissural posts (26) formed by the haunches (22) of adjacent elements (18). The leaflets (12) each have an attachment edge (28) and a free edge (30) with a belly (32) extending therebetween. The leaflets (12) are movable between a coapted condition, in which the free edges (30) abut and prevent fluid flow through the valve (10), and an open condition, in which fluid flow through the valve (10) is permitted. The leaflets (12) are made from a polymeric material and are moulded directly onto the stent (14) so as to provide for continuous attachment thereof.
    • 提供了一种假体心脏瓣膜(10),该假体心脏瓣膜(10)包括具有附接到其上的三个小叶(12)的支架(14)。 支架(14)是可压缩的,以便能够通过微创手术引入患者体内并且具有在其高度上限定三个弓形元件(18)的环状主体(16)。 每个元件(18)包括弧(20)和从其相对侧延伸的一对隆起(22),并具有由相邻元件(18)的隆起(22)形成的三个连合柱(26)。 小叶(12)每个都具有附接边缘(28)和自由边缘(30),并具有在其间延伸的腹部(32)。 小叶12可在其中自由边缘30邻接并防止流体流过阀10的合适状态和允许流体流过阀10的打开状态之间移动。 小叶(12)由聚合物材料制成并直接模制在支架(14)上以提供其连续附接。