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1. 发明申请

US20060293406A1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 失效
公开(公告)号：US20060293406A1
公开(公告)日：2006-12-28
申请号：US11511133
申请日：2006-08-28
申请人： Steven Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
发明人： Steven Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
IPC分类号： A61L17/00 , A61L27/00
CPC分类号： C08G81/00 , A61L24/046 , C08G63/06 , C08G63/66 , C08G63/664 , C08G63/912 , Y10T428/31551 , C08L67/04
摘要： Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.

2. 发明申请

US20060014023A9 BIOABSORBABLE BRANCHED POLYMERS CONTAINING UNITS DERIVED FROM DIOXANONE AND MEDICAL/SURGICAL DEVICES MANUFACTURED THEREFROM 有权
标题翻译：包含二氧化钛衍生的单体的生物可分支聚合物及其制造的医疗/外科设备
公开(公告)号：US20060014023A9
公开(公告)日：2006-01-19
申请号：US10630945
申请日：2003-07-30
申请人： Steven Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
发明人： Steven Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
IPC分类号： B32B27/00
CPC分类号： C08G81/00 , A61L24/046 , C08G63/06 , C08G63/66 , C08G63/664 , C08G63/912 , Y10T428/31551 , C08L67/04
摘要： Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.
摘要翻译：软链段形成单体的星形聚合物可用于形成外科装置。星形聚合物可以用异氰酸酯封端，与填料混合和/或交联。聚合物组合物可用作例如纤维涂层，手术粘合剂或骨腻子或组织生长底物。

3. 发明授权

US07321008B2 Bioabsorbable branched polymers end-capped with diketene acetals 失效
标题翻译：用双烯酮缩醛封端的生物可吸收支化聚合物
公开(公告)号：US07321008B2
公开(公告)日：2008-01-22
申请号：US11511133
申请日：2006-08-28
申请人： Steven L. Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
发明人： Steven L. Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
IPC分类号： C08L65/26 , C08L65/331 , A61L31/06
CPC分类号： C08G81/00 , A61L24/046 , C08G63/06 , C08G63/66 , C08G63/664 , C08G63/912 , Y10T428/31551 , C08L67/04
摘要： Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with diketene acetals, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.
摘要翻译：软链段形成单体的星形聚合物可用于形成外科装置。星形聚合物可以用双烯酮缩醛封端，与填料混合和/或交联。聚合物组合物可用作例如纤维涂层，手术粘合剂或骨腻子或组织生长底物。

4. 发明授权

US07097907B2 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 有权
公开(公告)号：US07097907B2
公开(公告)日：2006-08-29
申请号：US10630945
申请日：2003-07-30
申请人： Steven L. Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
发明人： Steven L. Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
IPC分类号： A61L31/10 , C09D167/04
CPC分类号： C08G81/00 , A61L24/046 , C08G63/06 , C08G63/66 , C08G63/664 , C08G63/912 , Y10T428/31551 , C08L67/04
摘要： Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.

5. 发明授权

US06339130B1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 有权
标题翻译：含有衍生自二恶烷酮的单元的生物可吸收支化聚合物和由其制造的医疗/手术装置
公开(公告)号：US06339130B1
公开(公告)日：2002-01-15
申请号：US09282724
申请日：1999-03-31
申请人： Steven L. Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
发明人： Steven L. Bennett , Kevin Connolly , Elliott Gruskin , Ying Jiang
IPC分类号： A61L2404
CPC分类号： C08G81/00 , A61L24/046 , C08G63/06 , C08G63/66 , C08G63/664 , C08G63/912 , Y10T428/31551 , C08L67/04
摘要： Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.
摘要翻译：软链段形成单体的星形聚合物可用于形成外科装置。星形聚合物可以用异氰酸酯封端，与填料混合和/或交联。聚合物组合物可用作例如纤维涂层，手术粘合剂或骨腻子或组织生长底物。

6. 发明申请

US20050196830A1 Amino acid modified polypeptides 审中-公开
标题翻译：氨基酸修饰的多肽
公开(公告)号：US20050196830A1
公开(公告)日：2005-09-08
申请号：US10104793
申请日：2002-03-22
申请人： Elliott Gruskin , Douglas Buechter , Guanghui Zhang , Kevin Connolly
发明人： Elliott Gruskin , Douglas Buechter , Guanghui Zhang , Kevin Connolly
IPC分类号： C07K14/47 , C07K14/495 , C07K14/51 , C07K14/75 , C07K14/78 , C12N1/21 , C12N15/12 , C12P21/02
CPC分类号： C07K14/75 , C07K14/4725 , C07K14/495 , C07K14/51 , C07K14/78 , C07K2319/00 , C12P21/02
摘要： Methods are disclosed for simplified recombinant production of fibrillar collagens. DNAs encoding fibrillar collagen monomers lacking the N propeptide, the C propeptide, or both propeptides are introduced into recombinant host cells and expressed. Trimeric collagen is recovered from the recombinant host cells.
摘要翻译：公开了简单的重组生产纤维胶原蛋白的方法。将缺乏N前肽，C前肽或两种前肽的纤维胶原单体的DNA引入重组宿主细胞中并进行表达。从重组宿主细胞中回收三聚体胶原。

7. 发明申请

US20060178506A1 Amino acid modified polypeptides 审中-公开
标题翻译：氨基酸修饰的多肽
公开(公告)号：US20060178506A1
公开(公告)日：2006-08-10
申请号：US11048197
申请日：2005-02-01
申请人： Elliott Gruskin , Douglas Buechter , Guanghui Zhang , Kevin Connolly
发明人： Elliott Gruskin , Douglas Buechter , Guanghui Zhang , Kevin Connolly
IPC分类号： C07H21/04
CPC分类号： C12P21/02 , C07K14/51 , C07K14/78 , C07K2319/00
摘要： Incorporation of certain amino acid analogs into polypeptides produced by cells which do not-ordinarily provide polypeptides containing such amino acid analogs is accomplished by subjecting the cells to growth media containing such amino acid analogs. The degree of incorporation can be regulated by adjusting the concentration of amino acid analogs in the media and/or by adjusting osmolality of the media. Such incorporation allows the chemical and physical characteristics of polypeptides to be altered and studied. In addition, nucleic acid and corresponding proteins including a domain from a physiologically active peptide and a domain from an extracellular matrix protein which is capable of providing a self-aggregate are provided. Human extracellular matrix proteins capable of providing a self-aggregate collagen are provided which are produced by prokaryotic cells. Preferred codon usage is employed to produce extracellular matrix proteins in prokaryotics.
摘要翻译：将某些氨基酸类似物并入通常不提供含有这种氨基酸类似物的多肽的细胞产生的多肽中，是通过使细胞经受含有这种氨基酸类似物的生长培养基来完成的。可以通过调节培养基中氨基酸类似物的浓度和/或通过调节培养基的重量摩尔渗透压浓度来调节掺入程度。这种结合允许改变和研究多肽的化学和物理特性。此外，提供核酸和相应的蛋白质，包括来自生理活性肽的结构域和能够提供自聚集体的细胞外基质蛋白的结构域。提供能够提供自身骨胶原蛋白的人细胞外基质蛋白，其由原核细胞产生。使用优选的密码子用于在原核生物中产生细胞外基质蛋白。

8. 发明授权

US08075651B2 Ellipsoid exhaust intake bonnet (EIB) for maritime emissions control system 有权
标题翻译：用于海洋排放控制系统的椭球排气阀（EIB）
公开(公告)号：US08075651B2
公开(公告)日：2011-12-13
申请号：US12356862
申请日：2009-01-21
申请人： Sal Caro , Kevin Connolly , Jason McAuley
发明人： Sal Caro , Kevin Connolly , Jason McAuley
IPC分类号： A01F25/00 , A01F25/10
CPC分类号： F23J11/04 , B01D2259/4558 , B08B15/02
摘要： An improved Exhaust Intake Bonnet (EIB) for an Advanced Maritime Emissions Control System (AMECS) includes a ribbed frame lowered and then drawn around a stack of an Ocean Going Vessel (OGV), and a shroud unfurled over the ribbed frame. The ribbed frame has a more flexible structure to better conform to rectangular and oval stacks. The bonnet includes a peak with a duct for receiving exhaust gasses captured by the shroud. The bonnet is positioned over the stack using a deployment arm. A duct carries exhaust from the stack to an Advanced Maritime Emissions Control Unit (AMECU) where the exhaust gasses are processed before releasing to the air. The AMECU) may reside on a ship, a barge, a trailer next to a docked OGV, or be a stationary AMECU) on a dock.
摘要翻译：高级海事排放控制系统（AMECS）的改进的排气入口阀盖（EIB）包括一个下降的肋框架，然后围绕一个海洋船（OGV）的一堆，以及展开在肋框架上的护罩。肋框架具有更灵活的结构，以更好地符合矩形和椭圆形堆叠。发动机罩包括一个带有用于接收由护罩捕获的废气的管道的顶部。使用部署臂将发动机罩定位在堆叠上。管道将排气从堆叠运送到高级海事排放控制单元（AMECU），排放气体在释放到空气之前被处理。 AMECU）可以驻留在码头上的船舶，驳船，停靠的OGV旁边的拖车上，或者是固定的AMECU）。

9. 发明授权

US07832338B2 Exhaust intake bonnet for capturing exhausts from diesel-powered locomotives 有权
标题翻译：用于从柴油机车上捕获废气的排气阀
公开(公告)号：US07832338B2
公开(公告)日：2010-11-16
申请号：US11370373
申请日：2006-03-08
申请人： Sal Caro , Kevin Connolly
发明人： Sal Caro , Kevin Connolly
IPC分类号： E04H6/00 , E21F1/00
CPC分类号： B61C5/04 , B61C5/02
摘要： A bonnet captures exhaust gases from the exhaust pipes of diesel-powered locomotives. The bonnet includes a shell with a compliant fender. One or more of the bonnets are positioned over the exhaust pipe or pipes of the locomotive and are secured to the exhaust pipes or to a top surface of the locomotive. The bonnets are connected to a manifold, and the manifold carries the exhaust gasses to an Emissions Control Unit (ECU) for processing. The bonnets enclose a volume above and/or around the exhaust pipes and the compliant bumper closes against the internal or external surface of the exhaust pipe or pipes or against the top surface of the locomotive surrounding the exhaust pipe or pipes. The closing prevents or limits outside air from entering the bonnet and the exhaust gases from being emitted to the atmosphere.
摘要翻译：发动机罩从柴油机车的排气管中捕获废气。发动机罩包括带有柔性挡板的外壳。一个或多个阀芯定位在机车的排气管或管道上方，并且固定到排气管或机车的顶表面。阀盖连接到歧管，歧管将废气运送到排放控制单元（ECU）进行处理。阀盖包围排气管的上方和/或周围的体积，并且顺从的缓冲器抵靠排气管或管道的内表面或外表面或靠近排气管或管道周围的机车的顶表面。关闭防止或限制外部空气进入发动机罩，并排放废气排放到大气中。

10. 发明申请

US20070209544A1 Exhaust intake bonnet for capturing exhausts from diesel-powered locomotives 有权
标题翻译：用于从柴油机车上捕获废气的排气阀
公开(公告)号：US20070209544A1
公开(公告)日：2007-09-13
申请号：US11370373
申请日：2006-03-08
申请人： Sal Caro , Kevin Connolly
发明人： Sal Caro , Kevin Connolly
IPC分类号： B61C17/00
CPC分类号： B61C5/04 , B61C5/02
摘要： A bonnet captures exhaust gases from the exhaust pipes of diesel-powered locomotives. The bonnet includes a shell with a compliant fender. One or more of the bonnets are positioned over the exhaust pipe or pipes of the locomotive and are secured to the exhaust pipes or to a top surface of the locomotive. The bonnets are connected to a manifold, and the manifold carries the exhaust gasses to an Emissions Control Unit (ECU) for processing. The bonnets enclose a volume above and/or around the exhaust pipes and the compliant bumper closes against the internal or external surface of the exhaust pipe or pipes or against the top surface of the locomotive surrounding the exhaust pipe or pipes. The closing prevents or limits outside air from entering the bonnet and the exhaust gases from being emitted to the atmosphere.
摘要翻译：发动机罩从柴油机车的排气管中捕获废气。发动机罩包括带有柔性挡板的外壳。一个或多个阀芯定位在机车的排气管或管道上方，并且固定到排气管或机车的顶表面。阀盖连接到歧管，歧管将废气运送到排放控制单元（ECU）进行处理。阀盖包围排气管的上方和/或周围的体积，并且顺从的缓冲器抵靠排气管或管道的内表面或外表面或靠近排气管或管道周围的机车的顶表面。关闭防止或限制外部空气进入发动机罩，并排放废气排放到大气中。

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