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1. 发明授权

US07629329B2 Method for increasing muscle mass and strength through administration of adenosine triphosphate 有权
标题翻译：通过施用三磷酸腺苷来增加肌肉质量和强度的方法
公开(公告)号：US07629329B2
公开(公告)日：2009-12-08
申请号：US11069746
申请日：2005-02-28
申请人： Steve S. Lee , Richard B. Hynson , Joe Zhou
发明人： Steve S. Lee , Richard B. Hynson , Joe Zhou
IPC分类号： A01N43/04 , A61K31/70
CPC分类号： A61K31/7076
摘要： The present invention is directed to compositions having an effective amount of Adenosine Triphosphate (“ATP”) sufficient to effect intracellular and extracellular concentrations of ATP in a mammal to improve anaerobic exercise capacity by increasing muscle size and/or strength and methods for using the same. Preferably, a gastric acid secretion inhibitory coating is applied to the effective amount of ATP in a manner that protects the ATP from degradation by gastric juices. ATP compositions of the present invention may be administered in nutraceutical or functional food dosage forms, including oral and non-oral delivery forms. In addition, the effective amount of ATP maybe combined with amino acids, botanicals, functional foods, herbals, nucleotides, nutraceuticals, nutrients, pharmaceuticals, proteins, and/or vitamins in an effort to enhance the targeted activity of the composition.
摘要翻译：本发明涉及具有足以实现哺乳动物中ATP的细胞内和细胞外浓度的有效量的三磷酸腺苷（“ATP”）的组合物，以通过增加肌肉尺寸和/或强度来提高厌氧运动能力，并且使用该方法。优选地，以有效量的ATP将胃酸分泌抑制性涂层以保护ATP免受胃液降解的方式施用。本发明的ATP组合物可以以营养食品或功能性食品剂型给药，包括口服和非口服递送形式。此外，ATP的有效量可以与氨基酸，植物药，功能性食品，草药，核苷酸，营养品，营养素，药物，蛋白质和/或维生素组合，以增强组合物的靶向活性。

2. 发明授权

US09320816B2 Methods of treating cell culture media for use in a bioreactor 有权
标题翻译：用于生物反应器的细胞培养基处理方法
公开(公告)号：US09320816B2
公开(公告)日：2016-04-26
申请号：US12663837
申请日：2008-06-12
申请人： Joe Zhou , Felix M. Solamo
发明人： Joe Zhou , Felix M. Solamo
IPC分类号： C12N13/00 , A61L2/00
CPC分类号： A61L2/0011 , A61L2/0017
摘要： The invention provides methods for treating cell culture media for use in a bioreactor using ultraviolet C (UVC) light and filtration.
摘要翻译：本发明提供了使用紫外线（UVC）光和过滤处理用于生物反应器的细胞培养基的方法。

3. 发明申请

US20080132688A1 Methods for Removing Viral Contaminants During Protein Purification 审中-公开
标题翻译：蛋白质纯化过程中去除病毒污染物的方法
公开(公告)号：US20080132688A1
公开(公告)日：2008-06-05
申请号：US11859234
申请日：2007-09-21
申请人： Joe Zhou
发明人： Joe Zhou
IPC分类号： C07K1/02
CPC分类号： A61L2/0017
摘要： The present invention relates, in general, to methods for removing viral contaminants from therapeutic protein solutions to improve safety of therapeutic proteins administered to patients. Particularly contemplated is the removal of small non-enveloped viruses, such as parvovirus, from therapeutic protein solutions.
摘要翻译：本发明一般涉及从治疗性蛋白质溶液中除去病毒污染物以改善给予患者的治疗性蛋白质的安全性的方法。特别考虑的是从治疗性蛋白质溶液中去除小的非包膜病毒，如细小病毒。

4. 发明授权

US08632234B1 LED and fiber optic ring pathway light 有权
标题翻译： LED和光纤环通路灯
公开(公告)号：US08632234B1
公开(公告)日：2014-01-21
申请号：US13315578
申请日：2011-12-09
申请人： Tien S. Lowe , Mark Velutini , Eli E. Rivera , Joe Zhou , Francisco Biancuzzo
发明人： Tien S. Lowe , Mark Velutini , Eli E. Rivera , Joe Zhou , Francisco Biancuzzo
IPC分类号： F21V7/04
CPC分类号： F21S8/081
摘要： Pathway and landscape lights, in particular to devices, apparatus, systems and methods of using ground directed pathway and landscape lights with a single or perimeter spaced apart LED (light emitting diode) light sources on a disc mount, with or without an optical fiber arranged in a ring pattern about a perimeter edge of the mount. A light shade lens can have an upper end attached to the lower face of the disc mount, and a bottom end attached to a ground engaging post, so the light emitted from the mount is directed in a 360 degree outwardly expanding direction expanding outward on the ground surface where the ground engaging post is in the center of the 360 degree expanding illumination. A low voltage power source can be used. Alternatively, the light can be solar powered. The light forms uniform light beam emissions without shadow spots effects.
摘要翻译：通道和景观灯，特别是使用地面导向路径和景观灯与在盘安装件上具有或不具有光纤的单个或周边间隔开的LED（发光二极管）光源的设备，设备，系统和方法围绕安装座的周边边缘的环形图案。遮光透镜可以具有附接到盘安装件的下表面的上端，以及附接到地面接合柱的底端，使得从安装座发射的光被引导到向外扩展的360度向外扩展方向地面接地柱位于360度扩展照明的中心。可以使用低压电源。或者，光可以是太阳能供电的。光线形成均匀的光束发射，不产生阴影点影响。

5. 发明申请

US20070221054A1 Fluid Actuator with Limit Sensors and Fluid Limit Valves 有权
标题翻译：带限位传感器和流体极限阀的液压执行机构
公开(公告)号：US20070221054A1
公开(公告)日：2007-09-27
申请号：US11691482
申请日：2007-03-26
申请人： Timothy David Webster , Joe Zhou
发明人： Timothy David Webster , Joe Zhou
IPC分类号： F15B15/22
CPC分类号： F15B15/1409 , F15B15/149 , F15B15/204 , F15B15/225
摘要： A fluid actuator with fluid limit valves (550, 551) and optional adjustable mechanical limits enables the construction of fluid linkages which are able to completely replace mechanical linkages. In a fluid circuit comprising of two or more fluid actuators, the pistons (102) of the fluid actuators can become uncorrelated when fluid leakage occurs. At the piston (102) extension and retraction limits, fluid limit valves (550, 551) open. The open fluid limit valves (550, 551) allow fluid to bypass pistons (102) and/or allow fluid from an external source to compensate the fluid leakage. The fluid bypassing pistons (102) at their extension or retraction limit and/or externally supplied fluid forces the uncorrelated pistons (102) to reach their extension or retraction limit as well. The fluid actuator with optional adjustable mechanical limits have one or more additional pistons (686, 688), which have an adjustable separation from the main piston (102) or end of cylinder. The fluid actuator with fluid limit valves (550, 551) and optional adjustable mechanical limits enables mechanical linkages to be replaced by fluid circuits composed of the fluid actuators.
摘要翻译：具有流体限制阀（550,551）和可选可调机械限制的流体致动器使得能够完全替代机械连杆的流体连杆的构造。在包括两个或更多个流体致动器的流体回路中，当发生流体泄漏时，流体致动器的活塞（102）可能变得不相关。在活塞（102）延伸和缩回极限时，流体限制阀（550,551）打开。打开的流体限制阀（550,551）允许流体旁路活塞（102）和/或允许来自外部源的流体补偿流体泄漏。在其延伸或缩回极限和/或外部供应的流体旁路活塞（102）迫使不相关的活塞（102）达到其伸出或缩回极限。具有可选可调机械极限的流体致动器具有一个或多个附加的活塞（686,688），其具有与主活塞（102）或气缸端部可调节的间隔。具有流体限制阀（550,551）和可选的可调节机械限制的流体致动器使机械联动能够被由流体致动器组成的流体回路替代。

6. 发明申请

US20050216324A1 System and method for constructing a schedule that better achieves one or more business goals 审中-公开
标题翻译：用于构建更好地实现一个或多个业务目标的时间表的系统和方法
公开(公告)号：US20050216324A1
公开(公告)日：2005-09-29
申请号：US11052883
申请日：2005-02-09
申请人： Ravi Maithell , Joe Zhou , Adam McKee , Yin Zhou , Howard Lee , Trent McConaghy
发明人： Ravi Maithell , Joe Zhou , Adam McKee , Yin Zhou , Howard Lee , Trent McConaghy
IPC分类号： G06Q10/06 , G06F17/60
CPC分类号： G06Q10/06 , G06Q10/06312 , G06Q10/06313 , G06Q10/06314 , G06Q10/0637 , G06Q10/06375
摘要： A system and method for constructing a schedule that better achieves one or more business goals by generating a schedule optimized for at least one business goal comprising either a business objective or a business constraint. The present system and method, in addition to using information about the set of tasks, any information about constraints about the tasks, the available resources, the time to complete the tasks, all costs and any additional information in relation to the available resources, the present method, also uses information about the costs associated with the project, the sales revenues or fees earned by the project, customer satisfaction and alternative resources, in order to generate an optimized schedule meeting one or more defined business goals.
摘要翻译：一种用于构建通过生成针对包括业务目标或业务约束的至少一个业务目标优化的调度来更好地实现一个或多个业务目标的调度的系统和方法。目前的系统和方法除了使用关于该组任务的信息，关于任务的约束的任何信息，可用资源，完成任务的时间，所有成本以及与可用资源相关的任何附加信息，目前的方法，还使用与项目相关的成本，项目获得的销售收入或费用，客户满意度和替代资源的信息，以便产生满足一个或多个定义的业务目标的优化计划。

7. 发明申请

US20050032538A1 Buffering initial talk burst 失效
标题翻译：缓冲初始谈话爆发
公开(公告)号：US20050032538A1
公开(公告)日：2005-02-10
申请号：US10635300
申请日：2003-08-06
申请人： Paul Noel , Bruce Riley , Laurel Salvador , Donna Sand , David Vollman , Joe Zhou
发明人： Paul Noel , Bruce Riley , Laurel Salvador , Donna Sand , David Vollman , Joe Zhou
IPC分类号： H04L12/56 , H04B7/24 , H04B7/26 , H04M3/56 , H04W4/10 , H04W84/08 , H04B7/00
CPC分类号： H04W4/10 , H04W76/45
摘要： In a telecommunications system (100), a method and apparatus for buffering the initial speech of an initial speaker in a push-to-talk call is disclosed. The method includes the steps of determining at least one participant or group to call (410, 510), sending a call request to the at least one participant or group (520), determining if the at least one participant or group is registered with the telecommunications system, notifying the initial speaker to begin speaking after determining at least one participant is registered with the telecommunications system but prior to connecting all called parties, receiving and digitizing voice packets from the initial speaker, storing the digitized data packets in a storage medium and transmitting the digitized voice packets when a predetermined packet transmission triggering event occurs. The apparatus for buffering the initial speech burst of an initial speaker in a call includes a first server (140) and a second server (150) communicatively connected to the first server. The second server is programmed to execute the steps of the method described above.
摘要翻译：在电信系统（100）中，公开了一种用于在即按即说呼叫中缓存初始说话者的初始语音的方法和装置。该方法包括以下步骤：确定至少一个参与者或组以呼叫（410,510），向所述至少一个参与者或组（520）发送呼叫请求，确定所述至少一个参与者或组是否已经被注册电信系统，在确定至少一个参与者在电信系统中注册之后但在连接所有被叫方之前通知初始说话者开始说话，接收和数字化来自初始说话者的语音分组，将数字化数据分组存储在存储介质中，当发生预定分组传输触发事件时发送数字化语音分组。用于在呼叫中缓冲初始说话者的初始语音突发的装置包括通信地连接到第一服务器的第一服务器（140）和第二服务器（150）。第二服务器被编程为执行上述方法的步骤。

8. 发明授权

US5817282A Reduction of nitrogen oxides 失效
标题翻译：还原氮氧化物
公开(公告)号：US5817282A
公开(公告)日：1998-10-06
申请号：US681145
申请日：1996-07-22
申请人： Desmond Radlein , Girard Simons , Klaus H. Oehr , Joe Zhou
发明人： Desmond Radlein , Girard Simons , Klaus H. Oehr , Joe Zhou
IPC分类号： B01D53/56 , C10L1/182 , C10L1/188 , C10L1/22 , C10L3/00 , C10L9/10 , C10L10/02 , C10L9/00
CPC分类号： C10L1/1828 , B01D53/56 , C10L1/1881 , C10L1/221 , C10L10/02 , C10L3/003 , C10L9/10
摘要： A method is provided for reducing the nitrogen oxide content of a flue gas produced by the combustion of fuel by introducing a nitrogen oxide removal agent into either the nitrogen oxide contaminated flue gas or the fuel to be combusted. The nitrogen oxide removal agent is the reaction product of a carbon compound in a pyrolysis liquor and a nitrogen compound such as ammonia, ammonium hydroxide or urea. The carbon compound is selected from carboxylic acids, phenols, esters, aldehydes and ketones. The pyrolysis liquor is derived from a feed stock containing cellulose, lignin or starch.
摘要翻译：提供了一种通过将氮氧化物去除剂引入到被氮氧化物污染的烟道气或要燃烧的燃料中来减少由燃料燃烧产生的烟道气的氮氧化物含量的方法。氮氧化物去除剂是热解液中的碳化合物与氨，氢氧化铵或尿素等氮化合物的反应产物。碳化合物选自羧酸，酚，酯，醛和酮。热解液源自含有纤维素，木质素或淀粉的原料。

9. 发明授权

US07717025B2 Fluid actuator with limit sensors and fluid limit valves 有权
标题翻译：带限位传感器和流体极限阀的流体致动器
公开(公告)号：US07717025B2
公开(公告)日：2010-05-18
申请号：US11691482
申请日：2007-03-26
申请人： Timothy David Webster , Ashu M. G. Solo , Joe Zhou
发明人： Timothy David Webster , Ashu M. G. Solo , Joe Zhou
IPC分类号： F15B15/18 , F01B31/00
CPC分类号： F15B15/1409 , F15B15/149 , F15B15/204 , F15B15/225
摘要： A fluid actuator with fluid limit valves (550, 551) and adjustable mechanical limits enables the construction of fluid linkages which are able to completely replace mechanical linkages. In a fluid circuit comprising of two or more fluid actuators, the pistons (102) of the fluid actuators can become uncorrelated when fluid leakage occurs. At the piston (102) extension and retraction limits, fluid limit valves (550, 551) open. The open fluid limit valves (550, 551) allow fluid to bypass pistons (102) and/or allow fluid from an external source to compensate the fluid leakage. The fluid bypassing pistons (102) at their extension or retraction limit and/or externally supplied fluid forces the uncorrelated pistons (102) to reach their extension or retraction limit as well. The fluid actuator with adjustable mechanical limits have one or more additional pistons (686, 688), which have an adjustable separation from the main piston (102) or end of cylinder. The fluid actuator with fluid limit valves (550, 551) and adjustable mechanical limits enables mechanical linkages to be replaced by fluid circuits composed of the fluid actuators.
摘要翻译：具有流体限制阀（550,551）和可调节的机械限制的流体致动器使得能够完全替代机械连接的流体连杆的构造。在包括两个或更多个流体致动器的流体回路中，当发生流体泄漏时，流体致动器的活塞（102）可能变得不相关。在活塞（102）延伸和缩回极限时，流体限制阀（550,551）打开。打开的流体限制阀（550,551）允许流体旁路活塞（102）和/或允许来自外部源的流体补偿流体泄漏。在其延伸或缩回极限和/或外部供应的流体旁路活塞（102）迫使不相关的活塞（102）达到其伸出或缩回极限。具有可调机械限制的流体致动器具有一个或多个附加的活塞（686,688），其具有与主活塞（102）或气缸端部的可调分隔。具有流体限制阀（550,551）和可调节的机械限制的流体致动器使机械连杆更换为由流体致动器组成的流体回路。

10. 发明申请

US20080038258A1 Polypeptides with Reduced Susceptibility to Oxidation and Methods of Making 审中-公开
标题翻译：具有降低的氧化敏感性的多肽和制备方法
公开(公告)号：US20080038258A1
公开(公告)日：2008-02-14
申请号：US11780942
申请日：2007-07-20
申请人： Joe Zhou
发明人： Joe Zhou
IPC分类号： C07K1/107 , A61K38/02 , C07K16/00 , C07K2/00 , A61K39/395
CPC分类号： C07K16/00 , A61K2039/505 , C07K14/00
摘要： The present invention relates in general to polypeptides having reduced susceptibility to oxidation, methods of selecting or making the polypeptides and methods of use thereof. The polypeptides having reduced susceptibility to oxidation are modified by amino acid substitution, deletion or insertion to confer reduced susceptibility to oxidation, thereby decreasing degradation of the polypeptide and extending the shelf-life and biological activity of the polypeptide under typical storage, handling and use conditions.
摘要翻译：本发明一般涉及对氧化的易感性降低的多肽，选择或制备多肽的方法及其使用方法。具有降低的氧化易感性的多肽通过氨基酸取代，缺失或插入被修饰以赋予氧化降低的易感性，从而降低多肽的降解并延长多肽在典型储存，处理和使用条件下的保质期和生物学活性。

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