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1. 发明授权

US08187157B2 Microtome blade changing apparatus for a knife holder of a microtome, and microtome 有权
标题翻译：用于切片机的刀架的切片机刀片更换装置和切片机
公开(公告)号：US08187157B2
公开(公告)日：2012-05-29
申请号：US11960001
申请日：2007-12-19
申请人： Stefan Thiem , Rolf Metzner , Christoph Schmitt
发明人： Stefan Thiem , Rolf Metzner , Christoph Schmitt
IPC分类号： B23Q3/155 , G01N1/06
CPC分类号： B26D7/2614 , B26D7/00 , Y10S83/954 , Y10T83/6492 , Y10T83/6499 , Y10T83/9457 , Y10T483/17
摘要： A microtome blade changing apparatus for a knife holder (1) of a microtome comprises a blade dispenser (4) storing unused blades and a blade container (5) for receiving used blades. The blade dispenser (4) and blade container (5) are respectively arranged adjacent to the knife holder (1). To reduce the risk of injury to an operator in the context of a blade changing operation, enable operation of the microtome blade changing apparatus reliably and in simple fashion, and allow economical manufacture of the microtome blade changing apparatus, the microtome blade changing apparatus is characterized in that an entraining element (13) manually actuable by an operator is provided, and is configured in such a way that an unused blade is transferable with the entraining element (13) from the blade dispenser (4) to the knife holder (1), and a used blade is thereby conveyable into the blade container (5).
摘要翻译：用于切片机的刀架（1）的切片机刀片更换装置包括存储未使用的刀片的刀片分配器（4）和用于接收使用的刀片的刀片容器（5）。叶片分配器（4）和叶片容器（5）分别布置成与刀架（1）相邻。为了在叶片更换操作的背景下降低对操作者的伤害的风险，能够可靠地且以简单的方式操作切片机刀片更换装置，并且允许经济地制造切片机刀片更换装置，切片机刀片更换装置的特征在于提供了由操作者可手动致动的夹带元件（13），并且被构造成使得未使用的刀片能够与夹带元件（13）从刀片分配器（4）转移到刀架（1），并且所使用的刀片由此可输送到刀片容器（5）中。

2. 发明申请

US20080148918A1 Microtome Blade Changing Apparatus For A Knife Holder Of A Microtome, And Microtome 有权
标题翻译：切片机刀片更换装置及切片机
公开(公告)号：US20080148918A1
公开(公告)日：2008-06-26
申请号：US11960001
申请日：2007-12-19
申请人： Stefan Thiem , Rolf Metzner , Christoph Schmitt
发明人： Stefan Thiem , Rolf Metzner , Christoph Schmitt
IPC分类号： B26D7/26
CPC分类号： B26D7/2614 , B26D7/00 , Y10S83/954 , Y10T83/6492 , Y10T83/6499 , Y10T83/9457 , Y10T483/17
摘要： A microtome blade changing apparatus for a knife holder (1) of a microtome comprises a blade dispenser (4) storing unused blades and a blade container (5) for receiving used blades. The blade dispenser (4) and blade container (5) are respectively arranged adjacent to the knife holder (1). To reduce the risk of injury to an operator in the context of a blade changing operation, enable operation of the microtome blade changing apparatus reliably and in simple fashion, and allow economical manufacture of the microtome blade changing apparatus, the microtome blade changing apparatus is characterized in that an entraining element (13) manually actuable by an operator is provided, and is configured in such a way that an unused blade is transferable with the entraining element (13) from the blade dispenser (4) to the knife holder (1), and a used blade is thereby conveyable into the blade container (5).
摘要翻译：用于切片机的刀架（1）的切片机刀片更换装置包括存储未使用的刀片的刀片分配器（4）和用于接收使用的刀片的刀片容器（5）。叶片分配器（4）和叶片容器（5）分别布置成与刀架（1）相邻。为了在叶片更换操作的背景下降低对操作者的伤害的风险，能够可靠且简单地操作切片机刀片更换装置，并且可以经济地制造切片机刀片更换装置，切片机刀片更换装置的特征在于提供了由操作者可手动致动的夹带元件（13），并且被构造成使得未使用的刀片能够与夹带元件（13）从刀片分配器（4）转移到刀架（1），并且所使用的刀片由此可输送到刀片容器（5）中。

3. 发明授权

US07273000B2 Rotary microtome and collection element for a rotary microtome 有权
标题翻译：旋转式切片机和旋转切片机的收集元件
公开(公告)号：US07273000B2
公开(公告)日：2007-09-25
申请号：US10823927
申请日：2004-04-14
申请人： Stefan Thiem , Roland Walter , Rolf Metzner
发明人： Stefan Thiem , Roland Walter , Rolf Metzner
IPC分类号： G01N1/06
CPC分类号： G01N1/06 , G01N2001/061 , Y10T83/222 , Y10T83/6492 , Y10T83/6667
摘要： A rotary microtome (1) is disclosed, having a base part (2) on which a microtome housing (4) and a knife holder (6) are arranged. Also provided is a collection element (8) that surrounds the knife holder on three sides, the collection element having a U-shaped base outline. Also provided are several clamping levers that are associated with the knife holder, at least one clamping lever for the knife holder being arranged operably on a first or a second outer side wall (18a, 18b). In addition, the bottom (12) of the collection element (8) has shaped on it an elevation (22) under which a mechanical coupling is guided from the clamping lever (10c) to the knife holder.
摘要翻译：公开了一种旋转切片机（1），其具有设置有切片机壳体（4）和刀架（6）的基部（2）。还提供了围绕三维侧的刀架的收集元件（8），该收集元件具有U形的基本轮廓。还提供有与刀架相关联的多个夹紧杆，用于刀架的至少一个夹紧杆可操作地布置在第一或第二外侧壁（18a，18b）上。此外，收集元件（8）的底部（12）已经在其上形成有高度（22），在该高度处将机械联接器从夹紧杆（10c）引导到刀架。

4. 发明申请

US20080014119A1 Receiving And Transferring Station For Coverslipped Specimen Slides 有权
标题翻译：接收和转移站用于覆盖样品幻灯片
公开(公告)号：US20080014119A1
公开(公告)日：2008-01-17
申请号：US11469600
申请日：2006-09-01
申请人： Rolf Metzner
发明人： Rolf Metzner
IPC分类号： B32B27/04 , G01N33/00 , C12M3/00
CPC分类号： B65G57/32 , G01N1/312 , G01N35/00029 , G01N2035/00039 , G01N2035/00089 , Y10T436/2575
摘要： A receiving and transferring station (1) for coverslipped specimen slides (2, 2′, 2″) comprises at least one vertically upright magazine frame (5), open toward the receiving side, for at least one specimen slide magazine (4) having horizontally oriented compartments (6), and a rotation apparatus, connected to the magazine frame (5) and having a vertically upright rotation axis, for conveying the magazine frame (5) from a receiving position (3) into a transferring position (8).
摘要翻译：用于盖玻片的标本滑块（2,2'，2“）的接收和传送站（1）包括至少一个朝向接收侧敞开的垂直竖立的仓库框架（5），用于至少一个标本滑动架（4）具有水平定向的隔室（6）和旋转装置，连接到料盒框架（5）并且具有垂直竖立的旋转轴线，用于将料盒框架（5）从接收位置（3）输送到转移位置（8 ）。

5. 发明申请

US20050059155A1 System and method for the unequivocal allocation of histological cassettes and specimen slides 有权
标题翻译：用于明确分配组织学盒和标本片的系统和方法
公开(公告)号：US20050059155A1
公开(公告)日：2005-03-17
申请号：US10936893
申请日：2004-09-09
申请人： Dag Graupner , Rolf Metzner
发明人： Dag Graupner , Rolf Metzner
IPC分类号： B01L3/00 , G01N1/06 , G01N1/28 , G01N1/31 , G01N35/00 , G01N1/00
CPC分类号： B01L3/545 , B01L2300/021 , B01L2300/0822 , G01N1/06 , G01N1/31 , G01N35/00732 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/2575
摘要： A system (100) and a method for the unequivocal allocation of histological cassettes (30) and specimen slides (60) is described. The system encompasses a microtome (1) and at least one reading unit (80). The data (33) of the histological cassette (30) and the data (33) of the at least one specimen slide (60) are read by means of the reading unit (80). The reading unit (80) is provided with at least one indicating element (83) that outputs a signal in accordance with the degree of correspondence between the data (33) of the histological cassette (30) and the data (33) on the specimen slide (60).
摘要翻译：描述了系统（100）和用于明确分配组织学盒（30）和标本片（60）的方法。系统包括切片机（1）和至少一个读取单元（80）。通过读取单元（80）读取组织学盒（30）的数据（33）和至少一个样本滑块（60）的数据（33）。读取单元（80）设置有至少一个指示元件（83），其根据组织学盒（30）的数据（33）与样本上的数据（33）之间的对应度输出信号幻灯片（60）。

6. 发明授权

US07867442B2 System and method for the unequivocal allocation of histological cassettes and specimen slides 有权
标题翻译：用于明确分配组织学盒和标本片的系统和方法
公开(公告)号：US07867442B2
公开(公告)日：2011-01-11
申请号：US10936893
申请日：2004-09-09
申请人： Dag Graupner , Rolf Metzner
发明人： Dag Graupner , Rolf Metzner
IPC分类号： G01N21/00
CPC分类号： B01L3/545 , B01L2300/021 , B01L2300/0822 , G01N1/06 , G01N1/31 , G01N35/00732 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/2575
摘要： A system (100) and a method for the unequivocal allocation of histological cassettes (30) and specimen slides (60) is described. The system encompasses a microtome (1) and at least one reading unit (80). The data (33) of the histological cassette (30) and the data (33) of the at least one specimen slide (60) are read by means of the reading unit (80). The reading unit (80) is provided with at least one indicating element (83) that outputs a signal in accordance with the degree of correspondence between the data (33) of the histological cassette (30) and the data (33) on the specimen slide (60).
摘要翻译：描述了系统（100）和用于明确分配组织学盒（30）和标本片（60）的方法。系统包括切片机（1）和至少一个读取单元（80）。通过读取单元（80）读取组织学盒（30）的数据（33）和至少一个样本滑块（60）的数据（33）。读取单元（80）设置有至少一个指示元件（83），其根据组织学盒（30）的数据（33）与样本上的数据（33）之间的对应度输出信号幻灯片（60）。

7. 发明授权

US07595025B2 Apparatus for producing tissue arrays 有权
标题翻译：用于生产组织阵列的装置
公开(公告)号：US07595025B2
公开(公告)日：2009-09-29
申请号：US11469013
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： G01N21/00 , C12M1/38 , G01N31/00 , C12M1/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array is described. At least one receiver block (1), and at least one donor block (2) that comprises tissue (3) to be investigated, are provided, a first hollow needle (4) for creating a cavity in the receiver block (1), and a second hollow needle (5) for removing a sample from the tissue (3) and introducing the sample (3) into the cavity of the receiver block (1), being present. A pantograph (6) is provided for positioning the first and/or the second hollow needle (4; 5) above the receiver block (1).
摘要翻译：描述了一种用于生产组织阵列的装置。提供至少一个接收器块（1）和包括待研究的组织（3）的至少一个施主块（2），用于在接收器块（1）中产生空腔的第一中空针（4）以及用于从组织（3）移除样本并将样品（3）引入到接收器块（1）的空腔中的第二空心针（5）。集电弓（6）用于将第一和/或第二中空针（4; 5）定位在接收器块（1）上方。

8. 发明申请

US20070087428A1 Apparatus For Producing Tissue Arrays 有权
标题翻译：用于生产组织阵列的装置
公开(公告)号：US20070087428A1
公开(公告)日：2007-04-19
申请号：US11469013
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： C12M1/36 , C12M1/38 , C12M3/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array is described. At least one receiver block (1), and at least one donor block (2) that comprises tissue (3) to be investigated, are provided, a first hollow needle (4) for creating a cavity in the receiver block (1), and a second hollow needle (5) for removing a sample from the tissue (3) and introducing the sample (3) into the cavity of the receiver block (1), being present. A pantograph (6) is provided for positioning the first and/or the second hollow needle (4; 5) above the receiver block (1).
摘要翻译：描述了一种用于生产组织阵列的装置。提供至少一个接收器块（1）和包括待研究的组织（3）的至少一个施主块（2），用于在接收器块（1）中产生空腔的第一中空针（4）以及用于从组织（3）移除样本并将样品（3）引入到接收器块（1）的空腔中的第二空心针（5）。集电弓（6）用于将第一和/或第二中空针（4; 5）定位在接收器块（1）上方。

9. 发明授权

US06231037B1 Cassette clamp for a microtome 有权
标题翻译：用于切片机的盒式夹具
公开(公告)号：US06231037B1
公开(公告)日：2001-05-15
申请号：US09288713
申请日：1999-04-09
申请人： Rolf Metzner
发明人： Rolf Metzner
IPC分类号： B25B100
CPC分类号： G01N1/06
摘要： A cassette clamp (1) for a microtome includes a base part (2) having fixed limit stops (3) and at least one pivotally mounted clamping jaw (5) biased by a spring (6) for receiving a cassette (4). The cassette (4) is clamped between the limit stops (3) and the clamping jaw (5) via the spring force. The clamping jaw (5) is connected to a pivot lever (7) that can be moved counter to the spring force from a cassette-clamping position into a cassette-exchange position. A first end (8a) of the spring (6) acts on the base part (2) and the second end (8b) of the spring (6) acts on the pivot lever (7). The pivot lever (7) is mounted on the base part (2) via a pivot axis (9) arranged between the first end (8a) of the spring and the second end (8b) of the spring. The spring (6) and the pivot lever (7) form a tilting clamp mechanism that can be activated by installing the cassette (4) when the cassette clamp (1) is in the cassette-exchange position.
摘要翻译：用于切片机的盒式夹具（1）包括具有固定限位挡块（3）的基部（2）和由用于接收盒（4）的弹簧（6）偏置的至少一个枢转安装的夹爪。盒（4）通过弹簧力夹在限位挡块（3）和夹爪（5）之间。夹钳（5）连接到枢转杆（7），该枢转杆（7）能够抵抗弹簧力从卡夹位置移动到卡盒更换位置。弹簧（6）的第一端（8a）作用在基部（2）上，弹簧（6）的第二端（8b）作用在枢转杆（7）上。枢转杆（7）经由布置在弹簧的第一端（8a）和弹簧的第二端（8b）之间的枢转轴线（9）安装在基座部分（2）上。弹簧（6）和枢转杆（7）形成倾斜夹紧机构，当夹具夹（1）处于盒更换位置时，可以通过安装盒（4）来启动。

10. 发明授权

US07595024B2 Apparatus for producing tissue arrays 失效
标题翻译：用于生产组织阵列的装置
公开(公告)号：US07595024B2
公开(公告)日：2009-09-29
申请号：US11468984
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： G01N21/00 , C12M1/38 , G01N31/00 , C12M1/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array, having at least one donor block (2) that comprises tissue (3) to be investigated, is described. A marked tissue section of the tissue (3) to be investigated is arranged on a specimen slide (22), a hollow needle (5) for removing a sample from the tissue (3) being present. A sighting device (12) is provided for positioning the hollow needle (5) above the donor block (2).
摘要翻译：描述了一种用于生产组织阵列的装置，其具有包括待研究的组织（3）的至少一个供体块（2）。要检查的组织（3）的标记组织部分布置在样本载玻片（22）上，用于从存在的组织（3）中去除样品的中空针（5）。提供了一种瞄准装置（12），用于将中空针（5）定位在供体块（2）的上方。

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