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1. 发明授权

US07595024B2 Apparatus for producing tissue arrays 失效
标题翻译：用于生产组织阵列的装置
公开(公告)号：US07595024B2
公开(公告)日：2009-09-29
申请号：US11468984
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： G01N21/00 , C12M1/38 , G01N31/00 , C12M1/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array, having at least one donor block (2) that comprises tissue (3) to be investigated, is described. A marked tissue section of the tissue (3) to be investigated is arranged on a specimen slide (22), a hollow needle (5) for removing a sample from the tissue (3) being present. A sighting device (12) is provided for positioning the hollow needle (5) above the donor block (2).
摘要翻译：描述了一种用于生产组织阵列的装置，其具有包括待研究的组织（3）的至少一个供体块（2）。要检查的组织（3）的标记组织部分布置在样本载玻片（22）上，用于从存在的组织（3）中去除样品的中空针（5）。提供了一种瞄准装置（12），用于将中空针（5）定位在供体块（2）的上方。

2. 发明授权

US07273000B2 Rotary microtome and collection element for a rotary microtome 有权
标题翻译：旋转式切片机和旋转切片机的收集元件
公开(公告)号：US07273000B2
公开(公告)日：2007-09-25
申请号：US10823927
申请日：2004-04-14
申请人： Stefan Thiem , Roland Walter , Rolf Metzner
发明人： Stefan Thiem , Roland Walter , Rolf Metzner
IPC分类号： G01N1/06
CPC分类号： G01N1/06 , G01N2001/061 , Y10T83/222 , Y10T83/6492 , Y10T83/6667
摘要： A rotary microtome (1) is disclosed, having a base part (2) on which a microtome housing (4) and a knife holder (6) are arranged. Also provided is a collection element (8) that surrounds the knife holder on three sides, the collection element having a U-shaped base outline. Also provided are several clamping levers that are associated with the knife holder, at least one clamping lever for the knife holder being arranged operably on a first or a second outer side wall (18a, 18b). In addition, the bottom (12) of the collection element (8) has shaped on it an elevation (22) under which a mechanical coupling is guided from the clamping lever (10c) to the knife holder.
摘要翻译：公开了一种旋转切片机（1），其具有设置有切片机壳体（4）和刀架（6）的基部（2）。还提供了围绕三维侧的刀架的收集元件（8），该收集元件具有U形的基本轮廓。还提供有与刀架相关联的多个夹紧杆，用于刀架的至少一个夹紧杆可操作地布置在第一或第二外侧壁（18a，18b）上。此外，收集元件（8）的底部（12）已经在其上形成有高度（22），在该高度处将机械联接器从夹紧杆（10c）引导到刀架。

3. 发明申请

US20070059816A1 Apparatus For Producing Tissue Arrays 失效
标题翻译：用于生产组织阵列的装置
公开(公告)号：US20070059816A1
公开(公告)日：2007-03-15
申请号：US11469048
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： C12M1/34
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array, having at least one receiver block (1) and at least one donor block (2) that comprises tissue (3) to be investigated, is described. The donor block (2) comprises tissue (3) to be investigated, a first hollow needle (4) for creating a cavity in the receiver block (1), and a second hollow needle (5) for removing a sample from the tissue (3) and introducing the sample (3) into the cavity of the receiver block (1), being provided. For positioning of the first and/or the second hollow needle (4; 5) above the receiver block (1) and/or the donor block (2), a positioning array (11) having predefined markings, as well as a movably mounted lever, are provided for transferring the position of the markings onto a corresponding position on the donor block (2) and/or onto a corresponding position on the receiver block (1).
摘要翻译：描述了一种用于生产组织阵列的装置，其具有包括待研究的组织（3）的至少一个接收器块（1）和至少一个施主块（2）。供体块（2）包括待研究的组织（3），用于在接收器块（1）中产生空腔的第一空心针（4）和用于从组织移除样品的第二空心针（5） 3）并将样品（3）引入到接收器块（1）的空腔中。为了在接收器块（1）和/或施体块（2）上方定位第一和/或第二中空针（4; 5），具有预定义标记的定位阵列（11）以及可移动地安装提供用于将标记的位置转移到施体块（2）上的对应位置和/或接收器块（1）上的相应位置上。

4. 发明授权

US07595025B2 Apparatus for producing tissue arrays 有权
标题翻译：用于生产组织阵列的装置
公开(公告)号：US07595025B2
公开(公告)日：2009-09-29
申请号：US11469013
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： G01N21/00 , C12M1/38 , G01N31/00 , C12M1/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array is described. At least one receiver block (1), and at least one donor block (2) that comprises tissue (3) to be investigated, are provided, a first hollow needle (4) for creating a cavity in the receiver block (1), and a second hollow needle (5) for removing a sample from the tissue (3) and introducing the sample (3) into the cavity of the receiver block (1), being present. A pantograph (6) is provided for positioning the first and/or the second hollow needle (4; 5) above the receiver block (1).
摘要翻译：描述了一种用于生产组织阵列的装置。提供至少一个接收器块（1）和包括待研究的组织（3）的至少一个施主块（2），用于在接收器块（1）中产生空腔的第一中空针（4）以及用于从组织（3）移除样本并将样品（3）引入到接收器块（1）的空腔中的第二空心针（5）。集电弓（6）用于将第一和/或第二中空针（4; 5）定位在接收器块（1）上方。

5. 发明申请

US20070087428A1 Apparatus For Producing Tissue Arrays 有权
标题翻译：用于生产组织阵列的装置
公开(公告)号：US20070087428A1
公开(公告)日：2007-04-19
申请号：US11469013
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： C12M1/36 , C12M1/38 , C12M3/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array is described. At least one receiver block (1), and at least one donor block (2) that comprises tissue (3) to be investigated, are provided, a first hollow needle (4) for creating a cavity in the receiver block (1), and a second hollow needle (5) for removing a sample from the tissue (3) and introducing the sample (3) into the cavity of the receiver block (1), being present. A pantograph (6) is provided for positioning the first and/or the second hollow needle (4; 5) above the receiver block (1).
摘要翻译：描述了一种用于生产组织阵列的装置。提供至少一个接收器块（1）和包括待研究的组织（3）的至少一个施主块（2），用于在接收器块（1）中产生空腔的第一中空针（4）以及用于从组织（3）移除样本并将样品（3）引入到接收器块（1）的空腔中的第二空心针（5）。集电弓（6）用于将第一和/或第二中空针（4; 5）定位在接收器块（1）上方。

6. 发明授权

US07597846B2 Apparatus for producing tissue arrays 失效
标题翻译：用于生产组织阵列的装置
公开(公告)号：US07597846B2
公开(公告)日：2009-10-06
申请号：US11469048
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： G01N21/00 , C12M1/38 , G01N31/00 , C12M1/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array, having at least one receiver block (1) and at least one donor block (2) that comprises tissue (3) to be investigated, is described. The donor block (2) comprises tissue (3) to be investigated, a first hollow needle (4) for creating a cavity in the receiver block (1), and a second hollow needle (5) for removing a sample from the tissue (3) and introducing the sample (3) into the cavity of the receiver block (1), being provided. For positioning of the first and/or the second hollow needle (4; 5) above the receiver block (1) and/or the donor block (2), a positioning array (11) having predefined markings, as well as a movably mounted lever, are provided for transferring the position of the markings onto a corresponding position on the donor block (2) and/or onto a corresponding position on the receiver block (1).
摘要翻译：描述了一种用于生产组织阵列的装置，其具有包括待研究的组织（3）的至少一个接收器块（1）和至少一个施主块（2）。供体块（2）包括待研究的组织（3），用于在接收器块（1）中产生空腔的第一空心针（4）和用于从组织移除样品的第二空心针（5） 3）并将样品（3）引入到接收器块（1）的空腔中。为了在接收器块（1）和/或施体块（2）上方定位第一和/或第二中空针（4; 5），具有预定义标记的定位阵列（11）以及可移动地安装提供用于将标记的位置转移到施体块（2）上的对应位置和/或接收器块（1）上的相应位置上。

7. 发明申请

US20070172942A1 Apparatus For Producing Tissue Arrays 失效
标题翻译：用于生产组织阵列的装置
公开(公告)号：US20070172942A1
公开(公告)日：2007-07-26
申请号：US11468984
申请日：2006-08-31
申请人： Roland Walter , Rolf Metzner
发明人： Roland Walter , Rolf Metzner
IPC分类号： C12M1/34 , G01N1/30 , C12M1/00
CPC分类号： G01N1/36 , G01N2001/368
摘要： An apparatus for producing a tissue array, having at least one donor block (2) that comprises tissue (3) to be investigated, is described. A marked tissue section of the tissue (3) to be investigated is arranged on a specimen slide (22), a hollow needle (5) for removing a sample from the tissue (3) being present. A sighting device (12) is provided for positioning the hollow needle (5) above the donor block (2).
摘要翻译：描述了一种用于生产组织阵列的装置，其具有包括待研究的组织（3）的至少一个供体块（2）。要检查的组织（3）的标记组织部分布置在样本载玻片（22）上，用于从存在的组织（3）中去除样品的中空针（5）。提供了一种瞄准装置（12），用于将中空针（5）定位在供体块（2）的上方。

8. 发明授权

US06568307B1 Microtome having a motorized feed drive system 有权
标题翻译：切片机具有电动进给驱动系统
公开(公告)号：US06568307B1
公开(公告)日：2003-05-27
申请号：US09524542
申请日：2000-03-13
申请人： Bernd Günther , Siegbert Holtermüller , Peter Scheck , Andreas Laudat , Rolf Metzner , Roland Walter
发明人： Bernd Günther , Siegbert Holtermüller , Peter Scheck , Andreas Laudat , Rolf Metzner , Roland Walter
IPC分类号： G01N106
CPC分类号： G01N1/06 , G01N2001/066 , Y10T83/536 , Y10T83/6577
摘要： A microtome (1) having a motorized feed drive system (2) for generating a relative movement between an object (7) that is to be cut and a cutting knife (4). A control circuit (8) and a pressure-sensitive sensor (9) are provided for detecting a position between the cutting knife (4) and the object (7). The motorized feed drive system (2) is switched via the control circuit (8) when the sensor (9) responds. The sensor (9) is equipped with a sensor surface (14) that is at least exactly as large as the surface (16) of the object (7). The sensor surface (14) is arranged parallel to the cutting plane (17).
摘要翻译：具有电动进给驱动系统（2）的切片机（1），用于在要切割的物体（7）和切割刀（4）之间产生相对运动。设置控制电路（8）和压敏传感器（9），用于检测切割刀（4）和物体（7）之间的位置。当传感器（9）响应时，电动进给驱动系统（2）通过控制电路（8）切换。传感器（9）配备有至少与物体（7）的表面（16）一样大的传感器表面（14）。传感器表面（14）平行于切割平面（17）设置。

9. 发明申请

US20050235542A1 Microtome for producing thin sections 审中-公开
标题翻译：切片机用于生产薄片
公开(公告)号：US20050235542A1
公开(公告)日：2005-10-27
申请号：US11103596
申请日：2005-04-12
申请人： Rolf Metzner , Roland Walter
发明人： Rolf Metzner , Roland Walter
IPC分类号： G01N1/06 , F41A3/00
CPC分类号： G01N1/06
摘要： A microtome for producing thin sections includes a knife holder (32) with a cutting knife (33), a sample holder (34) for samples (42) embedded in a cartridge (40), a feed device (31) for changing the distance between the cutting knife (33) and the cartridge (40), and a drive device for producing a cutting movement between the cutting knife (33) and the cartridge (40). The microtome also includes a reading device (54) for coded information (45) applied to a cartridge (40), and a control device (10) with a computer for coordination of functional sequences. A magazine (60) with code (62) and partitions (61) holds prepared cartridges (40), and a handling device (50) provides for the controllable removal of a cartridge (40) and positioning on the sample holder (34) as well as returning cartridges into the magazine (60). The reading device (54, 53) is assigned to the magazine housing and/or the handling device (50).
摘要翻译：用于生产薄片的切片机包括具有切割刀（33）的刀架（32），用于嵌入盒（40）中的样品（42）的样品保持器（34），用于改变距离在切割刀（33）和墨盒（40）之间，以及用于在切割刀（33）和墨盒（40）之间产生切割运动的驱动装置。切片机还包括用于应用于盒（40）的编码信息（45）的读取装置（54）和具有用于协调功能序列的计算机的控制装置（10）。具有代码（62）和隔板（61）的杂志（60）保持准备的盒（40），并且处理装置（50）提供可控制地移除盒（40）并且将样本保持器（34）定位为以及将墨盒送回杂志（60）。读取装置（54,53）被分配到盒仓和/或处理装置（50）。

10. 发明授权

US06715870B2 Method and apparatus for printing onto cassettes or specimen slides for histological preparations 有权
标题翻译：用于组织学制备的用于印刷到盒或标本载片上的方法和装置
公开(公告)号：US06715870B2
公开(公告)日：2004-04-06
申请号：US10106159
申请日：2002-03-26
申请人： Uwe Kiene , Manfred Biehl , Andreas Laudat , Holger Metzner , Rolf Metzner , Roland Walter
发明人： Uwe Kiene , Manfred Biehl , Andreas Laudat , Holger Metzner , Rolf Metzner , Roland Walter
IPC分类号： B41J201
CPC分类号： B41J11/002 , B41J3/4073 , B41J11/0015
摘要： A method and an apparatus for printing onto plastic cassettes for histological preparations and/or onto glass specimen slides for microscopic thin sections are described, in which a computing device (1) is provided to control the printing device (2), and the printing device (2) comprises an inkjet printer for printing onto the cassettes and/or specimen slides. The ink is pre-dried by way of a hot-air drier (3) and completely dried by way of a flash device (4).
摘要翻译：描述了用于印刷到用于组织学制备的塑料盒和/或用于微细薄片的玻璃样品载片上的方法和装置，其中提供计算装置（1）以控制打印装置（2），并且打印装置（2）包括用于打印到盒和/或标本片上的喷墨打印机。油墨通过热风干燥器（3）预干燥，并通过闪光装置（4）完全干燥。

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