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1. 发明授权

US5617867A Tonometer mounting device 失效
标题翻译：眼压计安装装置
公开(公告)号：US5617867A
公开(公告)日：1997-04-08
申请号：US344252
申请日：1994-11-23
申请人： Robert D. Butterfield , Charles R. Holdaway , Stephen A. Martin , Stanley J. Boyer , Christine A. Giurdanella-Renzi
发明人： Robert D. Butterfield , Charles R. Holdaway , Stephen A. Martin , Stanley J. Boyer , Christine A. Giurdanella-Renzi
IPC分类号： A61B5/021 , A61B5/00
CPC分类号： A61B5/021
摘要： A device for mounting a tonometry sensor upon a patient's wrist includes a base portion that is specifically adapted to generally conform to the patient's wrist while providing a stable placement of the tonometry sensor relative to a preselected artery. A sensor housing is movably mounted upon the base portion and configured such that the mounting device has an essentially equal thickness at each end of the device. A strap member is provided for releasably securing the mounting device to a patient's wrist. The mounting device facilitates more accurate, non-invasive blood pressure measurement by providing a stable placement of the tonometry sensor relative to the tissue overlying a preselected artery at a measurement location and, further, limits undesirable movement by the patient to thereby reduce undesirable error in the blood pressure measurement.
摘要翻译：用于将眼压测量传感器安装在患者腕部上的装置包括基部，该基部特别地适于大体上符合患者的手腕，同时提供相对于预选动脉的眼压测量传感器的稳定放置。传感器壳体可移动地安装在基座部分上并且构造成使得安装装置在装置的每个端部具有基本相等的厚度。提供带构件用于将安装装置可释放地固定到患者的手腕上。安装装置通过提供眼压计传感器相对于在测量位置处覆盖预选动脉的组织的稳定放置来促进更准确的无创血压测量，并且还限制了患者的不期望的运动，从而减少不期望的误差血压测量。

2. 发明授权

US5271405A Wrist mount apparatus for use in blood pressure tonometry 失效
标题翻译：用于血压眼压测量的手腕式装置
公开(公告)号：US5271405A
公开(公告)日：1993-12-21
申请号：US699859
申请日：1991-05-14
申请人： Stanley J. Boyer , Stephen A. Martin , Christine A. Giurdanella-Renzi , Charles R. Holdaway , Robert D. Butterfield
发明人： Stanley J. Boyer , Stephen A. Martin , Christine A. Giurdanella-Renzi , Charles R. Holdaway , Robert D. Butterfield
IPC分类号： A61B5/0205 , A61B5/021 , A61B5/022 , A61B5/00
CPC分类号： A61B5/021
摘要： A wrist mount apparatus for placing a tissue stress sensor in operative engagement with the tissue overlaying an artery of interest is disclosed for use in a system for noninvasively determining the intra-arterial blood pressure of a patient. The wrist mount apparatus comprises a base portion and a transducer platform which is pivotally and slidingly engaged to the base portion. This arrangement allows the apparatus to be used on either the right or the left wrist of the wearer. A force overload system is provided whereby the wearer is protected from excessive forces applied to the wrist tissue by the apparatus used to applanate the artery. A quick disconnect feature allows the tissue stress sensor to be removed from the wrist mount apparatus without necessitating the use of tools. A disposable, anticontamination film is used with each application of the wrist mount apparatus to minimize the risk of transferring contaminants from one wearer to another and to prevent a build up of materials on the sensor's face.
摘要翻译：公开了一种用于将组织应力传感器放置在与覆盖感兴趣的动脉的组织操作性接合的手腕安装装置，用于非侵入性地确定患者的动脉内血压的系统中。手腕安装装置包括基部和与枢转并滑动地接合到基部的换能器平台。这种布置允许该装置在佩戴者的右手腕或左手腕上使用。提供了一种力过载系统，由此佩戴者不受用于压迫动脉的装置施加到手腕组织的过大的力。快速断开功能允许组织应力传感器从手腕安装装置移除，而不需要使用工具。使用一次性的抗静电胶片，每一次使用手腕安装装置，以最大限度地减少将污染物从一个佩戴者转移到另一个佩戴者的危险，并防止传感器表面上的材料积聚。

3. 发明授权

US06290650B1 Tonometry system for monitoring blood pressure 有权
标题翻译：用于监测血压的血压计系统
公开(公告)号：US06290650B1
公开(公告)日：2001-09-18
申请号：US09321907
申请日：1999-05-28
申请人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
发明人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
IPC分类号： A61B502
CPC分类号： A61B5/021
摘要： A system for noninvasively continuously monitoring arterial blood pressure includes a tissue stress sensor that has a continuous diaphragm for sensing stress within tissue adjacent a preselected artery caused by arterial pulsations within that artery. The stress sensitive diaphragm is coupled with electromechanical means for producing electrical signals that represent the stress within the tissue that is communicated to the sensor. These signals are then processed electronically in order to yield an output that is indicative of the arterial blood pressure of the preselected artery. The disclosed system includes methods of operation for determining blood pressure while maintaining a preselected artery in an optimum applanation state and an off-optimum applanation state.
摘要翻译：用于非侵入性连续监测动脉血压的系统包括组织应力传感器，其具有用于感测由该动脉内的动脉脉动引起的预选动脉附近的组织内的应力的连续膜片。应力敏感隔膜与机电装置相结合，用于产生表示组织内传递到传感器的应力的电信号。然后电子地处理这些信号，以产生指示预选动脉的动脉血压的输出。所公开的系统包括用于确定血压的操作的方法，同时保持预选动脉处于最佳压扁状态和不合适的压扁状态。

4. 发明授权

US5908027A Tonometry system for monitoring blood pressure 失效
标题翻译：用于监测血压的血压计系统
公开(公告)号：US5908027A
公开(公告)日：1999-06-01
申请号：US848920
申请日：1997-05-01
申请人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
发明人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
IPC分类号： A61B5/021 , A61B5/02
CPC分类号： A61B5/021
摘要： A system for noninvasively continuously monitoring arterial blood pressure includes a tissue stress sensor that has a continuous diaphragm for sensing stress within tissue adjacent a preselected artery caused by arterial pulsations within that artery. The stress sensitive diaphragm is coupled with electromechanical means for producing electrical signals that represent the stress within the tissue that is communicated to the sensor. These signals are then processed electronically in order to yield an output that is indicative of the arterial blood pressure of the preselected artery. The disclosed system includes methods of operation for determining blood pressure while maintaining a preselected artery in an optimum applanation state and an off-optimum applanation state.
摘要翻译：用于非侵入性连续监测动脉血压的系统包括组织应力传感器，其具有用于感测由该动脉内的动脉脉动引起的预选动脉附近的组织内的应力的连续膜片。应力敏感隔膜与机电装置相结合，用于产生表示组织内传递到传感器的应力的电信号。然后电子地处理这些信号，以产生指示预选动脉的动脉血压的输出。所公开的系统包括用于确定血压的操作的方法，同时保持预选动脉处于最佳压扁状态和不合适的压扁状态。

5. 发明授权

US5158091A Tonometry system for determining blood pressure 失效
标题翻译：用于测定血压的测量系统
公开(公告)号：US5158091A
公开(公告)日：1992-10-27
申请号：US621165
申请日：1990-11-30
申请人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
发明人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
IPC分类号： A61B5/022 , A61B5/0225 , A61B5/024 , G01L7/00 , G01L9/00
CPC分类号： A61B5/021 , A61B5/02422 , A61B2560/0252 , A61B2562/0247 , A61B2562/043 , A61B5/7203
摘要： A tissue contact stress sensing system incorporates a semiconductor assembly and a continuous diaphragm to noninvasively determine the intra-arterial blood pressure of a patient. The system comprises a continuous diaphragm placed against a patient's tissue which covers an underlying artery. The semiconductor assembly is placed in close proximity to and spaced apart from the diaphragm for directly irradiating the diaphragm with electromagnetic radiation and receiving a portion of the electromagnetic radiation which is reflected from the continuous diaphragm. The disclosed system also utilizes a technique for minimizing the system errors associated with temperature drift and aging of the sensor.
摘要翻译：组织接触应力感测系统包括半导体组件和连续隔膜以非侵入性地确定患者的动脉内血压。该系统包括一个连续的隔膜，该隔膜相对于覆盖下面动脉的患者组织放置。半导体组件被放置在与隔膜紧密并且间隔开的位置，以便用电磁辐射直接照射隔膜并且接收从连续隔膜反射的电磁辐射的一部分。所公开的系统还利用用于最小化与传感器的温度漂移和老化相关的系统误差的技术。

6. 发明授权

US5284150A Tonometry system for determining blood pressure 失效
标题翻译：用于测定血压的血压计系统
公开(公告)号：US5284150A
公开(公告)日：1994-02-08
申请号：US962364
申请日：1992-10-16
申请人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
发明人： Robert D. Butterfield , Kenneth J. Pytel , Charles R. Holdaway , Stephen A. Martin
IPC分类号： A61B5/022 , A61B5/0225 , A61B5/024 , G01L7/00 , G01L9/00 , A61B5/021
CPC分类号： A61B5/021 , A61B5/02422 , A61B2560/0252 , A61B2562/0247 , A61B2562/043 , A61B5/7203
摘要： A tissue contact stress sensing system incorporates a semiconductor assembly and a continuous diaphragm to noninvasively determine the intra-arterial blood pressure of a patient. The system comprises a continuous diaphragm placed against a patient's tissue which covers an underlying artery. The semiconductor assembly is placed in close proximity to and spaced apart from the diaphragm for directly irradiating the diaphragm with electromagnetic radiation and receiving a portion of the electromagnetic radiation which is reflected from the continuous diaphragm. The disclosed system also utilizes a technique for minimizing the system errors associated with temperature drift and aging of the sensor.
摘要翻译：组织接触应力感测系统包括半导体组件和连续隔膜以非侵入性地确定患者的动脉内血压。该系统包括一个连续的隔膜，该隔膜相对于覆盖下面动脉的患者组织放置。半导体组件被放置在与隔膜紧密并且间隔开的位置，以便用电磁辐射直接照射隔膜并且接收从连续隔膜反射的电磁辐射的一部分。所公开的系统还利用用于最小化与传感器的温度漂移和老化相关的系统误差的技术。

7. 发明授权

US5534691A System for determining pumping mechanism position while limiting volume of fluid pumped 失效
标题翻译：用于确定泵送机构位置的系统，同时限制泵送的液体体积
公开(公告)号：US5534691A
公开(公告)日：1996-07-09
申请号：US304582
申请日：1994-09-12
申请人： Charles R. Holdaway , Eric A. Warner
发明人： Charles R. Holdaway , Eric A. Warner
IPC分类号： A61M5/00 , A61M5/142 , G01D5/249 , G01D5/347 , G01D5/34
CPC分类号： A61M5/14228 , G01D5/2492 , G01D5/347
摘要： A drive member of a peristaltic pumping mechanism includes a disk that rotates with the drive member and has two transparent sectors and two opaque sectors alternating with the transparent sectors. As a stepper motor rotates the drive member to pump fluid, a single optical sensor senses the disk and provides signals indicative of whether a transparent sector or opaque sector is being detected. A processor counts the number of motor steps in the detected transparent or opaque sector and based on the number of counted steps in a type of sector detected or the number of steps counted when a state change to the other type of sector occurs, determines the motor position. In another aspect, the position disk is integrally formed as a single piece with the cams and cam shaft of a pumping mechanism.
摘要翻译：蠕动泵送机构的驱动构件包括与驱动构件一起旋转并具有两个透明扇区和与透明扇区交替的两个不透明扇区的盘。当步进电机使驱动构件旋转以泵送流体时，单个光学传感器感测盘并且提供指示是否检测到透明扇区或不透明扇区的信号。处理器对检测到的透明或不透明扇区中的电机步数进行计数，并且基于检测到的扇区类型中的计数步数或当状态改变到另一类扇区时计数的步数，确定电动机位置。在另一方面，定位盘与泵送机构的凸轮和凸轮轴一体地形成为一体。

8. 发明授权

US06582368B2 Medical instrument sheath comprising a flexible ultrasound transducer 失效
标题翻译：包括柔性超声波换能器的医疗仪器护套
公开(公告)号：US06582368B2
公开(公告)日：2003-06-24
申请号：US09836880
申请日：2001-04-17
申请人： Charles R. Holdaway , Paul F. Zupkas , David G. Matsuura
发明人： Charles R. Holdaway , Paul F. Zupkas , David G. Matsuura
IPC分类号： A61B800
CPC分类号： A61B5/6848 , A61B8/0841 , A61B8/12 , A61B8/4444 , A61B8/4483 , A61B2562/164
摘要： An ultrasound transducer comprises a sheath body constructed from a nonconductive material. The sheath body is configured to be installed over a medical device. A piezoelectric copolymer transducer is held snugly against the medical device by the sheath body when the ultrasound transducer is installed over the medical device. The piezoelectric copolymer transducer transduces incident ultrasound signals into corresponding electric signals. A ground conductor is coupled to a first surface of the piezoelectric copolymer transducer. A signal conductor is coupled to a second surface of the piezoelectric copolymer transducer and conducts the corresponding electric signals to a proximal end of the medical device.
摘要翻译：超声换能器包括由非导电材料构成的护套主体。护套主体构造成安装在医疗装置上。当超声换能器安装在医疗装置上时，压电共振换能器通过护套主体紧贴地保持在医疗装置上。压电共振换能器将入射超声波信号转换成相应的电信号。接地导体耦合到压电共振换能器的第一表面。信号导体耦合到压电共振换能器的第二表面，并将相应的电信号传导到医疗装置的近端。

9. 发明授权

US06217518B1 Medical instrument sheath comprising a flexible ultrasound transducer 失效
公开(公告)号：US06217518B1
公开(公告)日：2001-04-17
申请号：US09164603
申请日：1998-10-01
申请人： Charles R. Holdaway , Paul F. Zupkas , David G. Matsuura
发明人： Charles R. Holdaway , Paul F. Zupkas , David G. Matsuura
IPC分类号： A61B800
CPC分类号： A61B5/6848 , A61B8/0841 , A61B8/12 , A61B8/4444 , A61B8/4483 , A61B2562/164
摘要： An ultrasound transducer comprises a sheath body constructed from a nonconductive material. The sheath body is configured to be installed over a medical device. A piezoelectric copolymer transducer is held snugly against the medical device by the sheath body when the ultrasound transducer is installed over the medical device. The piezoelectric copolymer transducer transduces incident ultrasound signals into corresponding electric signals. A ground conductor is coupled to a first surface of the piezoelectric copolymer transducer. A signal conductor is coupled to a second surface of the piezoelectric copolymer transducer and conducts the corresponding electric signals to a proximal end of the medical device.

10. 发明授权

US6016044A Open-loop step motor control system 失效
公开(公告)号：US6016044A
公开(公告)日：2000-01-18
申请号：US526468
申请日：1995-09-11
申请人： Charles R. Holdaway
发明人： Charles R. Holdaway
IPC分类号： A61M5/00 , H02P8/04 , H02P8/14 , H02P8/22 , H02P8/24 , H02P8/28 , H02P8/32
CPC分类号： H02P8/22 , H02P8/04 , H02P8/24 , H02P8/32
摘要： A motor control system that reduces noise while reducing power requirements but providing sufficient torque. A one-phase-on drive mode modified to microstep between "one phase on" positions is used to accelerate the motor in a non-linear manner to a maximum speed. The microstep drive modes have a constant period, and the step rate of the motor is increased by decreasing the number of microsteps in succeeding steps of the motor. A modified full step waveform maintains the motor at the maximum speed, where the current to one winding of the step motor changes polarity within one motor step while the other remains approximately constant providing increased smoothness in the drive and reduced noise. The polarity changes in accordance with the inductance and the compliance voltage of the motor. A one-phase-on waveform modified to include microsteps between "one phase on" positions later decelerates the motor in a non-linear manner, and the motor stops in a detent position until another waveform of steps is delivered to the motor.

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