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1. 发明申请

WO2008083104A3 DUAL BRAIDED SHAFT 审中-公开
公开(公告)号：WO2008083104A3
公开(公告)日：2008-07-10
申请号：PCT/US2007/088657
申请日：2007-12-21
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , FUENTES, Allan M. , STEHR, Richard E. , TEGG, Troy T. , JOHNSON, Michael J.
发明人： STEHR, Richard E. , TEGG, Troy T. , JOHNSON, Michael J.
IPC分类号： A61M25/00
摘要： A dual braided catheter shaft includes a flat wire forming the inner braid, thereby potentially allowing for reduced radial thickness of the shaft. In one embodiment, the shaft (100) includes an inner polymer jacket (104), an inner braid (106) formed on the inner jacket (104), an intermediate jacket (108) formed over the inner braid (106), an outer braid (110) formed on the intermediate jacket (108) and an outer jacket (112) formed on the outer braid (110). A preferred construction process involves extruding polymer material directly onto each of the inner and outer braids (106 and 110) so that little or no air gaps remain between the polymer material and the braids (106 and 110). The braiding parameters of the inner and outer braids (106 and 110) can be varied along the length of the catheter to provide varying mechanical properties.

2. 发明申请

WO2008115665A1 CATHETER EMPLOYING SHAPE MEMORY ALLOY SHAPING WIRE OR PULL WIRE AND METHOD OF ITS MANUFACTURE 审中-公开
标题翻译：导管形状形状记忆合金成形线或拉丝及其制造方法
公开(公告)号：WO2008115665A1
公开(公告)日：2008-09-25
申请号：PCT/US2008/054971
申请日：2008-02-26
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HASTINGS, John M. , LATRAILLE, Gary B. , STEHR, Richard E. , FUENTES, Allan M.
发明人： HASTINGS, John M. , LATRAILLE, Gary B. , STEHR, Richard E. , FUENTES, Allan M.
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61B18/1492 , A61M25/0009 , A61M25/0012 , A61M25/005 , A61M25/0053 , A61M25/0147 , A61M25/0152 , A61M2025/0046 , A61N1/0565
摘要： An electrophysiology catheter includes an elongate catheter body having a distal end and a proximal end, a catheter tip including at least one metallic catheter component, such as an electrode, thereon, and at least one internal catheter component joined to the at least one metallic catheter component. The at least one internal catheter component includes a shape memory alloy and a metal compound that is capable of both bonding with the shape memory alloy and being metallurgically joined to the at least one metallic catheter component as by brazing. The metal compound may be a coating on or a core within the shape memory alloy. Suitable metal compounds include, without limitation, nickel, copper, brass, and combinations thereof.
摘要翻译：电生理导管包括具有远端和近端的细长导管主体，导管末端包括至少一个金属导管部件，例如其上的电极，以及连接到至少一个金属导管的至少一个内部导管部件零件。所述至少一个内部导管部件包括形状记忆合金和金属化合物，所述金属化合物能够与所述形状记忆合金结合并且通过钎焊与所述至少一种金属导管部件冶金结合。金属化合物可以是形状记忆合金内或外层的涂层。合适的金属化合物包括但不限于镍，铜，黄铜及其组合。

3. 发明申请

WO2009088697A1 CATHETER SHAFT AND METHOD OF MANUFACTURE 审中-公开
标题翻译：导管轴和制造方法
公开(公告)号：WO2009088697A1
公开(公告)日：2009-07-16
申请号：PCT/US2008/087511
申请日：2008-12-18
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , TEGG, Troy T. , STEHR, Richard E. , FUENTES, Allan M. , NEMEC, Linda
发明人： TEGG, Troy T. , STEHR, Richard E. , FUENTES, Allan M. , NEMEC, Linda
IPC分类号： A61M25/00
CPC分类号： A61M25/005 , A61M25/0009 , A61M25/0043 , A61M25/0045 , F16L11/085
摘要： A method of manufacturing a catheter assembly generally includes providing a catheter shaft (10) having an outer layer (20) and an inner reinforcing layer (30); removing at least a portion of the outer layer (20) from a length of the distal end (50) of the catheter shaft (10) in order to expose a distal segment thereof; providing an inner jacket segment (80); axially engaging the inner jacket segment (80) with an interior surface of the distal segment of the catheter shaft (10); providing an outer jacket segment (25) around at least the exposed exterior region of the distal segment of the catheter shaft (10); and bonding the distal segment of the catheter shaft (10) to the inner jacket segment (80) and the outer jacket segment (25).
摘要翻译：制造导管组件的方法通常包括提供具有外层（20）和内增强层（30）的导管轴（10）。从导管轴（10）的远端（50）的长度移除外层（20）的至少一部分，以便露出其远端段; 提供内护套段（80）; 将内护套部分（80）与导管轴（10）的远端段的内表面轴向接合; 提供围绕至少所述导管轴（10）的远端段的暴露的外部区域的外护套段（25）; 以及将所述导管轴（10）的远端部分结合到所述内护套部分（80）和所述外护套部分（25）。

4. 发明申请

WO2009085531A1 CATHETER SHAFT AND METHOD OF ITS MANUFACTURE 审中-公开
标题翻译：导管轴及其制造方法
公开(公告)号：WO2009085531A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/085185
申请日：2008-12-01
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , GUO, Xiaoping , STEHR, Richard E.
发明人： GUO, Xiaoping , STEHR, Richard E.
IPC分类号： A61M25/16
CPC分类号： A61M25/0012 , A61M25/0045 , A61M25/005
摘要： A method of manufacturing a catheter shaft includes the steps of forming an inner layer (26) of a first polymeric material, forming a plait matrix layer (30) including a second polymeric material about the inner layer (26), and forming an outer layer (32) of a third polymeric material about the plait matrix layer (30). The plait matrix layer (30) includes a braided wire mesh (28) partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer (26) and the third polymeric material forming the outer layer (32). The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.
摘要翻译：制造导管轴的方法包括以下步骤：形成第一聚合物材料的内层（26），形成围绕内层（26）的包含第二聚合材料的辫状基质层（30），并形成外层（30）的第三聚合物材料（32）。辫子基质层（30）包括部分或完全嵌入第二聚合物材料内的编织丝网（28），其不同于形成内层（26）的第一聚合物材料和形成外层（32）。第二聚合物材料具有比至少第一聚合物材料更高的屈服应变和/或更低的硬度，优选第一和第三聚合物材料。导管轴可以通过逐步挤出，共挤出和/或回流工艺形成。

5. 发明申请

WO2007137136A2 TRANSSEPTAL NEEDLE ASSEMBLIES AND METHODS 审中-公开
标题翻译： TRANSSEPTAL NEEDLE组装和方法
公开(公告)号：WO2007137136A2
公开(公告)日：2007-11-29
申请号：PCT/US2007/069180
申请日：2007-05-17
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HASSETT, James A. , STEHR, Richard E.
发明人： HASSETT, James A. , STEHR, Richard E.
IPC分类号： A61M29/00
CPC分类号： A61M25/0084 , A61B17/3478 , A61B17/3496 , A61M25/0606
摘要： The instant invention relates to transseptal access systems and methods for accessing the left atrium (52) from the right atrium (48) by crossing the interatrial septum (50). In particular, the instant invention is directed toward medical devices used with catheter assemblies in cardiology procedures that require transseptal puncture(s). The puncture assemblies (e.g., 10) have a moveable puncture device (e.g., 14) within a dilator (e.g., 16). The puncture device is biased in a retracted position. The position of the puncture assembly is precisely locatable. The puncture assembly is preferably flexible along the majority of the length of its and, therefore, can be used with any catheter assembly of any predetermined shape. The puncture device is adjustable from a position within the dilator to a position extending beyond the end of the dilator when necessary for use in transseptal procedures.
摘要翻译：本发明涉及通过穿过房间隔（50）从右心房（48）进入左心房（52）的经血管通路系统和方法。特别地，本发明涉及在需要经过心脏穿刺的心脏病学程序中与导管组件一起使用的医疗装置。穿刺组件（例如，10）在扩张器（例如，16）内具有可移动穿刺装置（例如14）。穿刺装置被偏置在缩回位置。穿刺组件的位置可精确定位。穿刺组件优选沿其大部分长度是柔性的，因此可以与任何预定形状的导管组件一起使用。穿刺装置可以从扩张器内的位置调节到延伸超出扩张器末端的位置，当需要用于经血管手术时。

6. 发明申请

WO2007136984A2 AUTO LOCK FOR CATHETER HANDLE 审中-公开
标题翻译：自动锁定电缆手柄
公开(公告)号：WO2007136984A2
公开(公告)日：2007-11-29
申请号：PCT/US2007/068269
申请日：2007-05-04
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SCHNEIDER, Clint , DUDNEY, Joshua L. , STEHR, Richard E. , TEGG, Troy T. , BEDNAREK, Michael C. , VANNEY, Guy P. , JENSEN, James , STINE, Michael W.
发明人： SCHNEIDER, Clint , DUDNEY, Joshua L. , STEHR, Richard E. , TEGG, Troy T. , BEDNAREK, Michael C. , VANNEY, Guy P. , JENSEN, James , STINE, Michael W.
IPC分类号： A61M25/00
CPC分类号： A61M25/0136
摘要： The present invention is a catheter actuation handle (14) for deflecting a distal end (18) of a tubular catheter body (12), the handle including an auto-locking mechanism, (54). The handle comprises upper and lower grip portions (24a, 24b), an actuator (20), and an auto-locking mechanism, (54). The auto-locking mechanism (54) is adapted to hold a deflected distal end (18) of the catheter (10) in place without input from the operator. When the distal end (18) of the catheter (10) is deflected from its zero position, it typically will seek a return to its zero position, and as a result exerts a force on the actuator (20). The auto-locking mechanism (54) acts by providing a second force that resists this force from the distal end (18) and holds the distal end (18) in place. As a result, the operator does not need to maintain contact with the buttons (22a, 22b) to maintain the distal end (18) in a set position.
摘要翻译：本发明是用于偏转管状导管主体（12）的远端（18）的导管致动手柄（14），该手柄包括自动锁定机构（54）。手柄包括上和下抓握部分（24a，24b），致动器（20）和自动锁定机构（54）。自动锁定机构（54）适于将导管（10）的偏转的远端（18）保持在适当的位置，而没有来自操作者的输入。当导管（10）的远端（18）从其零位偏转时，通常将寻求返回其零位置，并且因此对致动器（20）施加力。自动锁定机构（54）通过提供抵抗来自远端（18）的该力并将远端（18）保持在适当位置的第二力来起作用。结果，操作者不需要保持与按钮（22a，22b）的接触，以将远端（18）保持在设定位置。

7. 发明申请

WO2012068505A9 ELECTRODE CATHETER DEVICE WITH INDIFFERENT ELECTRODE FOR DIRECT CURRENT TISSUE THERAPIES 审中-公开
公开(公告)号：WO2012068505A9
公开(公告)日：2012-05-24
申请号：PCT/US2011/061475
申请日：2011-11-18
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , GRASSE, Martin Maitre , STEHR, Richard E. , BYRD, Israel Alexander , CLARK, Lynn Eleanor , DENO, D. Curtis , TEGG, Troy T. , KAUPHUSMAN, James V. , PAUL, Saurav , SCHWEITZER, Jeffrey A.
发明人： GRASSE, Martin Maitre , STEHR, Richard E. , BYRD, Israel Alexander , CLARK, Lynn Eleanor , DENO, D. Curtis , TEGG, Troy T. , KAUPHUSMAN, James V. , PAUL, Saurav , SCHWEITZER, Jeffrey A.
IPC分类号： A61B18/04
摘要： An electrode catheter device with indifferent electrode for direct current tissue therapies is disclosed. An example of the catheter device has a flexible tubing with at least one ablation electrode. The catheter device also may also be used with a sheath for introducing the flexible tubing inside a patient's body. An indifferent electrode on the sheath can provide a ground for a direct current (DC) pulse to deliver electrical energy and create an electrical field adjacent a tissue. Various other embodiments are also disclosed.

8. 发明申请

WO2010078453A1 OPTIC-BASED CONTACT SENSING ASSEMBLY AND SYSTEM 审中-公开
标题翻译：基于光学的接触感应组件和系统
公开(公告)号：WO2010078453A1
公开(公告)日：2010-07-08
申请号：PCT/US2009/069857
申请日：2009-12-30
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , PAUL, Saurav , TEGG, Troy T. , HEIMBECHER, Reed R. , STEHR, Richard E. , THAO, Riki Chou
发明人： PAUL, Saurav , TEGG, Troy T. , HEIMBECHER, Reed R. , STEHR, Richard E. , THAO, Riki Chou
IPC分类号： A61M25/01
CPC分类号： A61M39/10 , A61B5/0084 , A61B5/065 , A61B5/1076 , A61B5/6852 , A61B5/6885 , A61B18/1492 , A61B18/24 , A61B2017/00057 , A61B2017/00084 , A61B2090/065 , A61M25/0043 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0071 , A61M25/0074 , A61M25/01 , A61M25/0138 , A61M25/0141 , A61M2025/0002
摘要： A contact sensing assembly including a catheter and an electrode including a tip portion and a base portion, and a generally central axis, with the electrode being connected to a distal end of the catheter. Optical sensor(s) may be provided for emitting and/or receiving an optical signal, with a part of the optical signal being transverse to the central axis. Optical interference member(s) may be provided for interfering with the optical signal. A method for sensing contact force exerted by an electrode on a tissue includes directing an optical signal along a portion of a catheter, emitting and/or receiving an optical signal, with a part of the optical signal being at a predetermined angle relative to the central axis, and sensing changes in intensity of the optical signal based on displacement associated with the electrode tip portion based on the contact force exerted by the electrode on the tissue.
摘要翻译：一种接触检测组件，包括导管和包括尖端部分和基部部分的电极以及大致中心的轴线，电极连接到导管的远端。可以提供光学传感器用于发射和/或接收光学信号，其中一部分光学信号横向于中心轴线。可以提供光干涉构件以干涉光信号。用于感测由电极施加在组织上的接触力的方法包括沿着导管的一部分引导光学信号，发射和/或接收光信号，其中光信号的一部分相对于中心处于预定角度并且基于由电极施加在组织上的接触力，基于与电极末端部分相关联的位移来感测光信号的强度变化。

9. 发明申请

WO2009075989A1 STEERABLE CATHETER USING FLAT PULL WIRES AND HAVING TORQUE TRANSFER LAYER MADE OF BRAIDED FLAT WIRES 审中-公开
标题翻译：使用平面拉线并具有扭曲平直线的扭矩传递层的可变导管
公开(公告)号：WO2009075989A1
公开(公告)日：2009-06-18
申请号：PCT/US2008/083241
申请日：2008-11-12
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HEIDEMAN, Wayne A. , FUENTES, Allan M. , STEHR, Richard E. , CUMMING, Sarah , DUSTRUDE, Mark
发明人： HEIDEMAN, Wayne A. , FUENTES, Allan M. , STEHR, Richard E. , CUMMING, Sarah , DUSTRUDE, Mark
IPC分类号： A61M25/00
CPC分类号： A61M25/01 , A61M25/0012 , A61M25/0045 , A61M25/0053 , A61M25/0147 , A61M2025/015
摘要： A catheter assembly (110) includes an inner liner made of flexible material and an outer layer having a steering mechanism. The steering mechanism includes at least one flat wire (30) and a corresponding lumen through which the flat wire (30) may travel. The steering mechanism may also include at least one pull ring to which the flat wires are attached. A layer of heat shrink material may encompass the outer layer. A braided wire assembly (50) may also be provided in the outer layer (60), and may be formed by braiding a plurality of flat wires into a wire mesh. The overall cross-section of the catheter assembly is preferably substantially circular. A catheter shaft may include a plurality of segments of differing hardness characteristics. The outer layer typically comprises a melt processing polymer such that the catheter assembly (200) may be laminated using heat.
摘要翻译：导管组件（110）包括由柔性材料制成的内衬和具有转向机构的外层。转向机构包括至少一个扁平线（30）和扁平线（30）可以通过其行进的相应内腔。转向机构还可以包括至少一个牵引环，扁平线连接到该拉环上。一层热收缩材料可以包围外层。编织线组件（50）也可以设置在外层（60）中，并且可以通过将多根扁平线编织成丝网而形成。导管组件的整个横截面优选地基本上是圆形的。导管轴可以包括具有不同硬度特性的多个部分。外层通常包括熔融加工聚合物，使得导管组件（200）可以使用热层压。

10. 发明申请

WO2009012362A1 CATHETER AND INTRODUCER CATHETER HAVING TORQUE TRANSFER LAYER AND METHOD OF MANUFACTURE 审中-公开
标题翻译：具有扭矩传递层的导管和导引管及其制造方法
公开(公告)号：WO2009012362A1
公开(公告)日：2009-01-22
申请号：PCT/US2008/070287
申请日：2008-07-17
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HEIDEMAN, Wayne A. , FUENTES, Allan M. , STEHR, Richard E. , CUMMING, Sarah E.
发明人： HEIDEMAN, Wayne A. , FUENTES, Allan M. , STEHR, Richard E. , CUMMING, Sarah E.
IPC分类号： A61M25/00
CPC分类号： A61M25/005 , A61M25/0012 , A61M25/0045 , A61M25/0054 , A61M25/0662 , B23P19/04 , B29C43/146 , B29K2023/00 , B29K2027/12 , B29L2031/7542 , Y10T29/49826 , Y10T29/4998
摘要： The instant invention relates generally to catheters and to introducer catheters (100) used to help deliver catheters or other medical devices to locations within the human body. In particular, the instant invention relates to large diameter catheters and introducer catheters (100) having a torque transfer layer (204) that includes at least two flat wires (210) braided into a wire mesh. The flat wires (210) have a width of at least about 0.007 inches and a depth of at least about 0.003 inches. The lumen diameter of the catheter is at least about 6 French. The torque transfer layer (204) provides increased strength, flexibility, and kink resistance.
摘要翻译：本发明一般涉及用于帮助将导管或其他医疗装置输送到人体内的位置的导管和引导器导管（100）。特别地，本发明涉及具有扭转传递层（204）的大直径导管和导引器导管（100），该转矩传递层包括编织到丝网中的至少两条扁平线（210）。扁平线（210）具有至少约0.007英寸的宽度和至少约0.003英寸的深度。导管的管腔直径至少约为6法国。转矩传递层（204）提供增加的强度，柔韧性和抗扭结性。

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