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1. 发明申请

US20050196778A1 Nucleic acid analysis apparatus 审中-公开
标题翻译：核酸分析仪
公开(公告)号：US20050196778A1
公开(公告)日：2005-09-08
申请号：US11013403
申请日：2004-12-17
申请人： Shuhei Yamamoto , Muneo Maeshima , Katsunobu Hama , Satoshi Takahashi
发明人： Shuhei Yamamoto , Muneo Maeshima , Katsunobu Hama , Satoshi Takahashi
IPC分类号： G01N21/64 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/68 , G01N21/78 , G01N33/53 , G01N37/00
CPC分类号： C12Q1/6834 , G01N21/6452 , G01N21/6456 , G01N2201/062 , C12Q2565/619
摘要： An apparatus measures individual measurement sites on a DNA chip in a short period of time. The DNA chip is irradiated by light-emitting diodes (LEDs) so as to excite fluorescent dye at each measurement site, and fluorescence emitted from the individual measurement sites is detected all at once. Since substantially uniform measurement conditions can be obtained for each measurement site, measurement accuracy increases. The read mechanism requires less space and is less costly, thereby decreasing the failure rate and virtually eliminating the need for maintenance of the apparatus.
摘要翻译：一种装置在短时间内测量DNA芯片上的各个测量位置。 DNA芯片被发光二极管（LED）照射，以便在每个测量部位激发荧光染料，并且一次检测到从各测量点发射的荧光。由于每个测量点可以获得大致均匀的测量条件，所以测量精度提高。读取机构需要更少的空间并且成本更低，从而降低故障率并且几乎消除了维护设备的需要。

2. 发明授权

US5331369A Method of forming patterns and apparatus for carrying out the same 失效
标题翻译：形成图案的方法和进行该图案的装置
公开(公告)号：US5331369A
公开(公告)日：1994-07-19
申请号：US050324
申请日：1993-05-18
申请人： Tsuneo Terasawa , Katsunobu Hama , Soichi Katagiri
发明人： Tsuneo Terasawa , Katsunobu Hama , Soichi Katagiri
IPC分类号： G03F9/00 , H01L21/68 , G03B27/42 , G03B27/28 , G03B27/72
CPC分类号： G03F9/7026 , H01L21/682
摘要： A method of forming patterns and an apparatus for carrying out the same whereby semiconductor integrated circuits and the like are manufactured using reduction projection alignment. The invention primarily involves projecting patterns of a first substrate onto the surface of a second substrate via an optical projector to form a projection image of the patterns on the second substrate surface. A phase difference pattern is furnished on the plane or its equivalent where the patterns of the first substrate are located. The phase difference pattern affords a predetermined phase difference to the light passing therethrough. Light is irradiated at the phase difference pattern via the optical projector to project the phase difference pattern onto a detecting plane in the position equivalent to the surface of the second substrate. This forms a projection image of the phase difference pattern on the detecting plane. An optical detector is used to detect the light intensity distribution of the projection image of the phase difference pattern projected onto the detecting plane. The detected light intensity distribution is represented by detection signals which are processed so as to obtain the relative positional relationship between the focal plane of the patterns and the detecting plane by use of the optical projector. Finally, the position of the second substrate is controlled so that the position of the detecting plane coincides with that of the focal plane on the basis of the relative positional relationship obtained.
摘要翻译： PCT No.PCT / JP92 / 01200 Sec。 371日期：1993年5月18日 102（e）日期1993年5月18日PCT提交1992年9月21日PCT公布。出版物WO93 / 06618 日期：1993年1月4日。一种形成图案的方法及其执行装置，由此半导体集成电路等使用缩小投影对准制造。本发明主要涉及通过光学投影仪将第一衬底的图案投影到第二衬底的表面上以在第二衬底表面上形成图案的投影图像。在第一基板的图案所在的平面或其等效物上提供相位差图案。相位差图案对通过其的光提供预定的相位差。通过光学投影仪以相位差图案照射光，以将相位差图案投影到与第二基板的表面相当的位置的检测平面上。这就形成了检测平面上的相位差图案的投影图像。光检测器用于检测投射到检测平面上的相位差图案的投影图像的光强度分布。检测到的光强度分布由检测信号表示，其被处理以便通过使用光学投影仪来获得图案的焦平面与检测平面之间的相对位置关系。最后，根据获得的相对位置关系，控制第二基板的位置，使得检测面的位置与焦平面的位置一致。

3. 发明授权

US07787120B2 Spectrophotometer and liquid chromatography system 失效
标题翻译：分光光度计和液相色谱系统
公开(公告)号：US07787120B2
公开(公告)日：2010-08-31
申请号：US12146920
申请日：2008-06-26
申请人： Motohiro Yamazaki , Ryoji Inaba , Kosaku Toyosaki , Shintaro Kubo , Takashi Gomi , Katsunobu Hama , Kiyotoshi Mori , Hideyuki Akiyama
发明人： Motohiro Yamazaki , Ryoji Inaba , Kosaku Toyosaki , Shintaro Kubo , Takashi Gomi , Katsunobu Hama , Kiyotoshi Mori , Hideyuki Akiyama
IPC分类号： G01J3/10 , G01J3/36 , G01N21/33
CPC分类号： G01J3/10 , G02B5/283 , G02B27/1006 , G02B27/1086 , G02B27/145 , G02B27/148
摘要： Detection sensitivity is improved by increasing the amount of light of beams that irradiate a sample cell without causing saturation of a detector with ultraviolet beams or visible beams. This spectrophotometer includes a sample cell, which stores a sample to be measured, a visible light source and an ultraviolet light source each for supplying an incident beam that enters the sample, a spectroscope, which disperses a beam that has passed through the sample, an optical detector, which detects beams dispersed from such beam (spectrum), and a dichroic element which reflects or transmits ultraviolet beams from the ultraviolet light source and which transmits or reflects visible beams from the visible light source. Optics are configured such that ultraviolet beams and visible beams that have passed through or have been reflected by the dichroic element enter the sample cell.
摘要翻译：通过增加照射样品池的光束的光量而不会使紫外线束或可见光束的检测器饱和而提高检测灵敏度。该分光光度计包括存储待测样品，可见光源和紫外光源的样品池，每个用于提供进入样品的入射光束，分散已经通过样品的光束的分光器，检测从这种光束（光谱）分散的光束的光检测器，以及从紫外光源反射或透射紫外光束并从可见光源透射或反射可见光束的二向色元件。光学构造使得已经通过或已被二色性元件反射的紫外光束和可见光束进入样品池。

4. 发明申请

US20090009761A1 SPECTROPHOTOMETER AND LIQUID CHROMATOGRAPHY SYSTEM 失效
标题翻译：分光光度计和液相色谱系统
公开(公告)号：US20090009761A1
公开(公告)日：2009-01-08
申请号：US12146920
申请日：2008-06-26
申请人： Motohiro Yamazaki , Ryoji Inaba , Kosaku Toyosaki , Shintaro Kubo , Takashi Gomi , Katsunobu Hama , Kiyotoshi Mori , Hideyuki Akiyama
发明人： Motohiro Yamazaki , Ryoji Inaba , Kosaku Toyosaki , Shintaro Kubo , Takashi Gomi , Katsunobu Hama , Kiyotoshi Mori , Hideyuki Akiyama
IPC分类号： G01J3/26
CPC分类号： G01J3/10 , G02B5/283 , G02B27/1006 , G02B27/1086 , G02B27/145 , G02B27/148
摘要： Detection sensitivity is improved by increasing the amount of light of beams that irradiate a sample cell without causing saturation of a detector with ultraviolet beams or visible beams. This spectrophotometer includes a sample cell, which stores a sample to be measured, a visible light source and an ultraviolet light source each for supplying an incident beam that enters the sample, a spectroscope, which disperses a beam that has passed through the sample, an optical detector, which detects beams dispersed from such beam (spectrum), and a dichroic element which reflects or transmits ultraviolet beams from the ultraviolet light source and which transmits or reflects visible beams from the visible light source. Optics are configured such that ultraviolet beams and visible beams that have passed through or have been reflected by the dichroic element enter the sample cell.
摘要翻译：通过增加照射样品池的光束的光量而不会使紫外线束或可见光束的检测器饱和而提高检测灵敏度。该分光光度计包括存储待测样品，可见光源和紫外光源的样品池，每个用于提供进入样品的入射光束，分散已经通过样品的光束的分光器，检测从这种光束（光谱）分散的光束的光检测器，以及从紫外光源反射或透射紫外光束并从可见光源透射或反射可见光束的二向色元件。光学构造使得已经通过或已被二色性元件反射的紫外光束和可见光束进入样品池。

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