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1. 发明申请

US20100022404A1 Gene/protein marker for prediction or diagnosis of pharmacological efficacy of aurora a inhibitor 审中-公开
标题翻译：用于预测或诊断极光抑制剂药理功效的基因/蛋白质标记
公开(公告)号：US20100022404A1
公开(公告)日：2010-01-28
申请号：US12311535
申请日：2007-10-05
申请人： Shinichi Hasako , Koji Ichikawa , Hideto Kotani , Satomi Miki , Katsuyoshi Miyama , Toshiyasu Shimomura , Kazuhiko Takahashi , Kazunori Yamanaka
发明人： Shinichi Hasako , Koji Ichikawa , Hideto Kotani , Satomi Miki , Katsuyoshi Miyama , Toshiyasu Shimomura , Kazuhiko Takahashi , Kazunori Yamanaka
IPC分类号： C40B30/04 , C07H21/04 , C40B40/08 , C07K14/00 , C40B40/10
CPC分类号： C12Q1/6883 , A61K49/0004 , C12Q2600/158 , G01N33/5082 , G01N2333/912
摘要： [PROBLEMS] To provide: a gene marker or a protein marker for detecting whether or not an Aurora A inhibitor acts in a living body in an Aurora A-specific manner when the Aurora A inhibitor is administered to the living body; and a method for predicting or diagnosing the pharmacological efficacy of an Aurora A inhibitor by using the gene marker or the protein marker [MEANS FOR SOLVING PROBLEMS] A gene/protein marker for use in the prediction or diagnosis of the pharmacological efficacy of an Aurora A inhibitor, wherein the gene is a gene selected from the group consisting of Aurora B, Histone H3, BIRC5, PRC1, DLG7, TACC3 and KNTC2 or a gene having substantially the same function as that of the gene; and a method for predicting or diagnosing the pharmacological efficacy of an Aurora A inhibitor by using the gene/protein marker.
摘要翻译： [问题]提供：当将Aurora A抑制剂施用于生物体时，用于检测Aurora A抑制剂是否以Aurora A特异性方式作用于活体中的基因标记物或蛋白质标记物; 以及通过使用基因标记或蛋白质标记来预测或诊断Aurora A抑制剂的方法[用于解决问题]用于预测或诊断Aurora A的药理学功效的基因/蛋白质标记抑制剂，其中所述基因是选自Aurora B，组蛋白H3，BIRC5，PRC1，DLG7，TACC3和KNTC2的基因或与基因具有基本相同功能的基因; 以及通过使用基因/蛋白质标记物来预测或诊断Aurora A抑制剂的药理功效的方法。

2. 发明授权

US11061224B2 Optics of wearable display to increase eye-box 有权
公开(公告)号：US11061224B2
公开(公告)日：2021-07-13
申请号：US15842774
申请日：2017-12-14
申请人： Fusao Ishii , Mikiko Nakanishi , Kazuhiko Takahashi , Yuji Aburakawa , Keiichi Murakami
发明人： Fusao Ishii , Mikiko Nakanishi , Kazuhiko Takahashi , Yuji Aburakawa , Keiichi Murakami
IPC分类号： G02B27/00 , G02B27/01 , G02B27/30
摘要： A see-through image display system having an Exit-Pupil-Expander (EPE) to enlarge the eyebox of display is disclosed. The EPE uses a hologram functioning as a micro-lens-array as well as collimation lens.

3. 发明授权

US08865896B2 Method for preparing adenine compound 有权
标题翻译：制备腺嘌呤化合物的方法
公开(公告)号：US08865896B2
公开(公告)日：2014-10-21
申请号：US12863291
申请日：2009-01-16
申请人： Kazuki Hashimoto , Wataru Katoda , Kazuhiko Takahashi , Ayumu Kurimoto
发明人： Kazuki Hashimoto , Wataru Katoda , Kazuhiko Takahashi , Ayumu Kurimoto
IPC分类号： C07D473/02 , C07D413/14 , C07D473/18
CPC分类号： C07D473/18
摘要： A method for producing adenine compound (1): wherein m and n are independently an integer of 2 to 5, R1 is C1-6 alkyl group, R2 and R3 are the same or different, and hydrogen atom, or C1-6 alkyl group, or R2 and R3 are combined with an adjacent nitrogen atom to form pyrrolidine, morpholine, piperidine, piperazine, etc., and R4 is C1-3 alkyl group, which comprises a step of reacting compound (2): and compound (3): in the presence of a boron-containing reducing agent.
摘要翻译：一种腺嘌呤化合物（1）的制造方法，其中m和n分别为2〜5的整数，R1为C1-6烷基，R2和R3相同或不同，氢原子或C1-6烷基，或R2和R3与相邻的氮原子结合形成吡咯烷，吗啉，哌啶，哌嗪等，R4为C1-3烷基，其包括使化合物（2）与化合物（3）反应的步骤：：在含硼还原剂的存在下。

4. 发明申请

US20140197079A1 METHOD OF EJECTING FAULTY ABSORBENT ARTICLE 有权
标题翻译：喷射非吸收性物品的方法
公开(公告)号：US20140197079A1
公开(公告)日：2014-07-17
申请号：US14130155
申请日：2012-06-29
申请人： Kazuhiko Takahashi , Tomohiro Watanabe , Masanobu Miyaki
发明人： Kazuhiko Takahashi , Tomohiro Watanabe , Masanobu Miyaki
IPC分类号： A61F13/15
CPC分类号： A61F13/15764 , A61F13/15772 , B07C5/342
摘要： A method of ejecting a faulty absorbent article which includes a step of detecting a failure region of an absorbent article in which a failure location of the absorbent article exists, and a type of a failure in the failure region, by identifying a shape of the absorbent article in the course of the manufacturing line, a step of deciding the absorbent article to be ejected based on the detection result of the failure region and the type of failure in the step of detecting, and a step of disengaging, from the manufacturing line, the absorbent article decided in the step of deciding, and then ejecting the absorbent article in the course of the manufacturing line. In the step of deciding, the number of absorbent articles to be ejected in the step of ejecting is decided according to the failure region and the type of the failure.
摘要翻译：一种排出有缺陷的吸收性物品的方法，其包括检测存在吸收性物品的故障位置的吸收性物品的失效区域的步骤，以及破坏区域的失效类型，通过识别吸收性物品的形状在制造过程中的制品，基于故障区域的检测结果和检测步骤中的故障类型来决定要排出的吸收性物品的步骤，以及从生产线脱离的步骤，所述吸收性物品在制造过程中决定，然后喷射吸收性物品的步骤中决定。在决定步骤中，根据故障区域和故障类型来决定喷射步骤中要喷射的吸收性物品的数量。

5. 发明申请

US20140196585A1 METHOD OF EJECTING ABSORBENT ARTICLES 审中-公开
标题翻译：吸收制品的喷射方法
公开(公告)号：US20140196585A1
公开(公告)日：2014-07-17
申请号：US14130144
申请日：2012-06-29
申请人： Kazuhiko Takahashi , Tomohiro Watanabe , Masanobu Miyaki
发明人： Kazuhiko Takahashi , Tomohiro Watanabe , Masanobu Miyaki
IPC分类号： A61F13/15
CPC分类号： A61F13/15585 , A61F13/15723 , A61F13/15764 , A61F13/15772 , B65H29/62 , Y10T83/0448
摘要： A method of ejecting absorbent articles which comprises: a step of providing a joint portion where a trailing end of a continuous web is joined to a starting end of a next continuous web, a step of controlling a timing of supplying the continuous web so as to locate the joint portion at a central portion of the absorbent articles in a machine direction, based on a length of the continuous web from the joint portion up to a cutting location and a dimension of the absorbent articles in the machine direction of the continuous web; and a step of disengaging only absorbent articles having the joint portion and ejecting the absorbent articles in the course of the manufacturing line.
摘要翻译：一种喷射吸收性物品的方法，该方法包括：提供一连接部分的连接部分的连接部分的步骤，连续卷材的后端连接到下一连续卷材的起始端;控制连续卷材供给时间的步骤，基于连续幅材从连接部分到切割位置的长度以及吸收制品在连续幅材的纵向方向上的尺寸，将接合部分沿机器方向定位在吸收制品的中心部分处; 以及仅在具有关节部分的吸收制品脱离并在生产线的过程中喷射吸收制品的步骤。

6. 发明授权

US08717427B2 Endoscope 有权
标题翻译：内窥镜
公开(公告)号：US08717427B2
公开(公告)日：2014-05-06
申请号：US13748185
申请日：2013-01-23
申请人： Kazuhiko Takahashi
发明人： Kazuhiko Takahashi
IPC分类号： A62B1/04 , A61B1/00
CPC分类号： A61B1/05 , A61B1/00039 , A61B1/0016 , A61B1/0052 , G02B23/2476
摘要： An endoscope includes a bending operation knob inputting a bending operation of a bending section in first perpendicular directions, a touch surface which is exposed in an outer surface of a grip casing and on which a bending operation of the bending section in second perpendicular directions is input, and a positional information calculator calculating a positional information of a touched region with time, the touched region being a region that is touched in the touch surface. The endoscope includes a positional change detector detecting a positional change of the touched region when the bending operation of the bending section in the second perpendicular directions is input, and a drive controller controlling a drive state of a drive member in accordance with the positional change of the touched region.
摘要翻译：内窥镜包括：弯曲操作旋钮，其在第一垂直方向上输入弯曲部的弯曲操作;触摸面，其暴露在握持壳体的外表面中，并且弯曲部在第二垂直方向上的弯曲操作被输入以及位置信息计算器，随着时间计算触摸区域的位置信息，触摸区域是触摸面中被触摸的区域。所述内窥镜包括：当输入所述弯曲部在所述第二垂直方向上的弯曲操作时检测所述触摸区域的位置变化的位置变化检测器;以及驱动控制器，其根据所述第二垂直方向的位置变化来控制驱动部件的驱动状态被触动的地区。

7. 发明授权

US08304953B2 Rotating electrical machine 有权
标题翻译：旋转电机
公开(公告)号：US08304953B2
公开(公告)日：2012-11-06
申请号：US13035395
申请日：2011-02-25
申请人： Akihito Nakahara , Hiroyuki Mikami , Kazumasa Ide , Kazuhiko Takahashi , Kenichi Hattori
发明人： Akihito Nakahara , Hiroyuki Mikami , Kazumasa Ide , Kazuhiko Takahashi , Kenichi Hattori
IPC分类号： H02K1/02 , H02K1/06 , H02K9/00
CPC分类号： H02K1/20 , H02K1/02 , H02K1/16
摘要： A rotating electrical machine includes: a rotor comprising a rotor core and a field winding wound round the rotor core; and a stator comprising a stator core and a stator winding wound round the stator core. The stator is arranged in opposition to the rotor with a predetermined spacing therebetween. the stator core is formed by punching a split piece, which comprises teeth for insertion of the stator winding thereinto and a core back on an outer periphery thereof, from a magnetic steel sheet, and laminating a plurality of those circular configurations in an axial direction, in which a plurality of the split pieces are arranged in a circle in a circumferential direction. The stator core has magnetic steel sheets, which are different in magnetic permeability in a diametrical direction, laminated at an axial end region of and in an axial central region of the stator core.
摘要翻译：旋转电机包括：转子，包括转子芯和围绕转子芯缠绕的励磁绕组; 以及定子，其包括绕定子铁芯缠绕的定子铁芯和定子绕组。定子与转子相对设置，其间具有预定的间隔。定子铁芯通过冲压分割片而形成，该分割片包括用于将定子绕组插入其中的齿，并且在其外周上由磁性钢板冲压，并且沿轴向层叠多个这些圆形构造，其中多个分割片在圆周方向上以圆形排列。定子铁芯具有在直径方向上的磁导率不同的电磁钢板，层压在定子铁芯的轴向中心区域的轴向端部区域。

8. 发明申请

US20110046369A1 METHOD FOR PREPARING ADENINE COMPOUND 有权
标题翻译：制备腺嘌呤化合物的方法
公开(公告)号：US20110046369A1
公开(公告)日：2011-02-24
申请号：US12863291
申请日：2009-01-16
申请人： Kazuki Hashimoto , Wataru Katoda , Kazuhiko Takahashi , Ayumu Kurimoto
发明人： Kazuki Hashimoto , Wataru Katoda , Kazuhiko Takahashi , Ayumu Kurimoto
IPC分类号： C07D473/18
CPC分类号： C07D473/18
摘要： A method for producing adenine compound (1): wherein m and n are independently an integer of 2 to 5, R1 is C1-6 alkyl group, R2 and R3 are the same or different, and hydrogen atom, or C1-6 alkyl group, or R2 and R3 are combined with an adjacent nitrogen atom to form pyrrolidine, morpholine, piperidine, piperazine, etc., and R4 is C1-3 alkyl group, which comprises a step of reacting compound (2): and compound (3): in the presence of a boron-containing reducing agent.
摘要翻译：一种腺嘌呤化合物（1）的制造方法，其中m和n分别为2〜5的整数，R1为C1-6烷基，R2和R3相同或不同，氢原子或C1-6烷基，或R2和R3与相邻的氮原子结合形成吡咯烷，吗啉，哌啶，哌嗪等，R4为C1-3烷基，其包括使化合物（2）与化合物（3）反应的步骤：：在含硼还原剂的存在下。

9. 发明申请

US20090306469A1 ENDOSCOPE SYSTEM 有权
标题翻译：内窥镜系统
公开(公告)号：US20090306469A1
公开(公告)日：2009-12-10
申请号：US12541538
申请日：2009-08-14
申请人： Yoshitaka Umemoto , Kazuhiko Takahashi
发明人： Yoshitaka Umemoto , Kazuhiko Takahashi
IPC分类号： A61B1/00
CPC分类号： A61B1/018 , A61B1/00036 , A61B1/00147 , A61B1/00149 , A61B1/0057 , A61B18/1233 , A61B18/1492 , A61B2017/00973
摘要： An endoscope system includes at least an endoscope of the endoscope and an accessory, a placement unit on which the endoscope is adapted to be placed, a detecting unit configured to detect whether the endoscope is placed on the placement unit or not, an actuating unit for at least one of the endoscope and the accessory, an operating unit for operating the actuating unit, and a control unit configured to be switched between a normal mode wherein the actuating unit is controlled according to an operation to the operating unit and a restricting mode wherein the actuating unit is controlled regardless of an operation to the operating unit, on the basis of a result of detection by the detecting unit.
摘要翻译：内窥镜系统至少包括内窥镜的内窥镜和附件，配置有内窥镜的放置单元，被配置为检测内窥镜是否被放置在放置单元上的检测单元，用于所述内窥镜和附件中的至少一个，用于操作所述致动单元的操作单元，以及控制单元，被配置为在正常模式之间切换，其中所述致动单元根据对所述操作单元的操作被控制，基于检测单元的检测结果，执行单元被控制而不管对操作单元的操作。

10. 发明申请

US20090195091A1 Rotary Electric Machine Having Cooling Device and Electric Generating System Including the Machine 失效
标题翻译：具有冷却装置的旋转电机和包括机器的发电系统
公开(公告)号：US20090195091A1
公开(公告)日：2009-08-06
申请号：US12026646
申请日：2008-02-06
申请人： Akihito Nakahara , Akiyoshi Komura , Kazumasa Ide , Kazuhiko Takahashi , Kengo Iwashige , Kenichi Hattori
发明人： Akihito Nakahara , Akiyoshi Komura , Kazumasa Ide , Kazuhiko Takahashi , Kengo Iwashige , Kenichi Hattori
IPC分类号： H02K9/04 , H02K9/00
CPC分类号： H02K9/04 , G01K7/42 , G01K13/08
摘要： A rotary electric machine which is smoothly operated with high efficiency by adequately controlling the cooling gas flow as needed to keep the highest temperature inside the rotary electric machine below a predetermined limit. The rotary electric machine includes a stator with armature windings wound around a stator core, a rotor placed inside the stator in a rotatable manner, and a cooling device for controlling cooling gas flow. It further includes a device for measuring an ambient temperature and a device for detecting armature voltage and/or armature current and/or field current. The temperature inside the rotary electric machine is calculated from the measured ambient temperature, detection value by the detecting device and an directive value of cooling gas flow. And a calculated suitable value of cooling gas flow is determined according to the calculated temperature inside the rotary electric machine.
摘要翻译：一种旋转电机，其通过根据需要适当地控制冷却气体流动而将旋转电机内的最高温度保持在预定极限以下，能够高效地平稳地运转。旋转电机包括具有绕定子铁芯缠绕的电枢绕组的定子，以可旋转的方式设置在定子内部的转子，以及用于控制冷却气流的冷却装置。它还包括用于测量环境温度的装置和用于检测电枢电压和/或电枢电流和/或场电流的装置。旋转电机内的温度由测量环境温度，检测装置的检测值和冷却气流的指示值计算。并根据计算出的旋转电机内的温度来确定计算出的冷却气流量的合适值。

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