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1. 发明授权

US09414920B2 Instrument of patterning cusp for cardiac valve reconstruction and component thereof 有权
标题翻译：用于心脏瓣膜重建的图案化尖瓣仪及其部件
公开(公告)号：US09414920B2
公开(公告)日：2016-08-16
申请号：US14070706
申请日：2013-11-04
申请人： Shigeyuki Ozaki
发明人： Shigeyuki Ozaki
IPC分类号： A61B17/00 , A61F2/24
CPC分类号： A61F2/2415 , A61F2/2445 , A61F2/2496
摘要： In a case of repairing an aortic valve by forming a valve cusp with a biomembrane, the shape and the size of a valve cusp can be determined easily. An instrument including a valve cusp sizer for measuring the size of the valve cusp and a template for scribing lines for the shape of a valve cusp conforming to the measured size of the valve cusp, in which the valve cusp sizer has a plurality of differently-sized sizer blocks attached to each of the top ends of grip members respectively and each sizer block has an arcuate surface formed by cutting each of differently-sized circular cylinders at an angle conforming to the central angle for the commissure portions and, the template is formed with a scribing portion including a substantially semi-circular valve cusp base forming portion.
摘要翻译：在通过用生物膜形成阀尖来修复主动脉瓣的情况下，可以容易地确定阀尖的形状和尺寸。一种包括用于测量阀尖的尺寸的阀尖调整器的仪器和用于根据所测量的阀尖的尺寸对阀尖形状进行划线的模板，其中阀尖调整器具有多个不同的方式，并且每个分级器块具有通过以与合金部分的中心角度相符的角度切割每个不同尺寸的圆柱体而形成的弓形表面，并且形成模板具有包括基本上半圆形的阀尖头基部形成部分的划线部分。

2. 发明授权

US08043854B2 Method of decellularizing tissues 有权
标题翻译：脱细胞组织方法
公开(公告)号：US08043854B2
公开(公告)日：2011-10-25
申请号：US10556400
申请日：2004-05-12
申请人： Mitsuo Umezu , Kiyotaka Iwasaki , Shigeyuki Ozaki , Yuji Morimoto , Osamu Endo
发明人： Mitsuo Umezu , Kiyotaka Iwasaki , Shigeyuki Ozaki , Yuji Morimoto , Osamu Endo
IPC分类号： A01N1/00
CPC分类号： A61K35/34 , A61F2/2415 , Y10S623/901
摘要： In the transplant of a living organism tissue, such as a heart valve, taken from an animal, etc. into a human body, a cell removing solution for removing original cells from the living organism tissue is provided with flow approximately equal to the bloodstream of transplant recipient living body, and the living organism tissue is placed in the flow so as to effect immersion of the living organism tissue in the cell removing solution. In the immersion, it is preferred that the living organism tissue placed in the cell removing solution, while being rotated, be irradiated with microwave. As a result, original cells can be removed from the living organism tissue uniformly and reliably, so that the biocompatibility of living organism tissue after transplant can be enhanced.
摘要翻译：在将从动物等取出的生物体组织如心脏瓣膜等移植到人体内时，从生物体组织中除去原始细胞的细胞去除溶液具有大约等于移植受体活体，并将活体组织置于流中，以使活体组织浸入细胞去除溶液中。在浸渍中，优选将放置在细胞去除溶液中的活体组织在旋转的同时用微波照射。结果，原始细胞可以均匀可靠地从生物体组织中去除，从而可以提高移植后活体组织的生物相容性。

3. 发明申请

US20060212074A1 Method of removing cell 有权
标题翻译：去除细胞的方法
公开(公告)号：US20060212074A1
公开(公告)日：2006-09-21
申请号：US10556400
申请日：2004-05-12
申请人： Mitsuo Umezu , Kiyotaka Iwasaki , Shigeyuki Ozaki , Yuji Morimoto , Osamu Endo
发明人： Mitsuo Umezu , Kiyotaka Iwasaki , Shigeyuki Ozaki , Yuji Morimoto , Osamu Endo
IPC分类号： A61N1/39 , A01N1/02
CPC分类号： A61K35/34 , A61F2/2415 , Y10S623/901
摘要： In the transplant of a living organism tissue, such as a heart valve, taken from an animal, etc. into a human body, a cell removing solution for removing original cells from the living organism tissue is provided with flow approximately equal to the bloodstream of transplant recipient living body, and the living organism tissue is placed in the flow so as to effect immersion of the living organism tissue in the cell removing solution. In the immersion, it is preferred that the living organism tissue placed in the cell removing solution, while being rotated, be irradiated with microwave. As a result, original cells can be removed from the living organism tissue uniformly and reliably, so that the biocompatibility of living organism tissue after transplant can be enhanced.
摘要翻译：在将从动物等取出的生物体组织如心脏瓣膜等移植到人体内时，从生物体组织中除去原始细胞的细胞去除溶液具有大约等于移植受体活体，并将活体组织置于流中，以使活体组织浸入细胞去除溶液中。在浸渍中，优选将放置在细胞去除溶液中的活体组织在旋转的同时用微波照射。结果，原始细胞可以均匀可靠地从生物体组织中去除，从而可以提高移植后活体组织的生物相容性。

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