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1. 发明申请

US20060229236A1 Cyclic tetrapeptide compound and use thereof 审中-公开
标题翻译：环状四肽化合物及其用途
公开(公告)号：US20060229236A1
公开(公告)日：2006-10-12
申请号：US10500113
申请日：2002-12-27
申请人： Shigeki Satoh , Yasuharu Urano , Kazuhiko Osoda , Mitsuru Hosaka , Kozo Sawada , Takayuki Inoue , Hiroaki Mori , Shoji Takagaki , Takao Fujimura , Hideaki Matsuoka , Katsuhiko Yoshizawa
发明人： Shigeki Satoh , Yasuharu Urano , Kazuhiko Osoda , Mitsuru Hosaka , Kozo Sawada , Takayuki Inoue , Hiroaki Mori , Shoji Takagaki , Takao Fujimura , Hideaki Matsuoka , Katsuhiko Yoshizawa
IPC分类号： A61K38/12 , C07K5/12
CPC分类号： C07K5/126 , A61K38/12
摘要： A cyclic tetrapeptide compound of the formula (I): wherein R1 is hydrogen; R2 is lower alkyl, aryl, optionally substituted ar(lower)alkyl, heterocyclic(lower)alkyl, cyclo(lower)alkyl(lower)alkyl, lower alkylcarbamoyl(lower)alkyl or arylcarbamoyl(lower)alkyl; R3 and R4 are each independently hydrogen, lower alkyl, optionally substituted ar(lower)alkyl, optionally substituted heterocyclic(lower)alkyl or cyclo(lower)alkyl(lower)alkyl, or R3 and R4 are linked together to form lower alkylene or condensed ring, or one of R3 and R4 is linked to the adjacent nitrogen atom to form a ring; R5 is lower alkylene or lower alkenylene, Y is [wherein RY1 is hydrogen, halogen or optionally protected hydroxy, RY2 is hydrogen, halogen, lower alkyl or phenyl, and RY3 is hydrogen or lower alkyl]; R8 is hydrogen or lower alkyl; and n is an integer of 1 or 2, or a salt thereof.
摘要翻译：式（I）的环状四肽化合物：其中R 1是氢; R 2是低级烷基，芳基，任选取代的芳（低级）烷基，杂环（低级）烷基，环（低级）烷基（低级）烷基，低级烷基氨基甲酰基（低级）烷基或芳基氨基甲酰基烷基; R 3和R 4各自独立地为氢，低级烷基，任选取代的芳（低级）烷基，任选取代的杂环（低级）烷基或环（低级）烷基（低级））烷基或R 3和R 4连接在一起形成低级亚烷基或稠环，或者R 3和R 3中的一个 > 4 与相邻的氮原子连接形成环; R 5是低级亚烷基或低级亚烯基，Y是[其中R Y1是氢，卤素或任选保护的羟基，R Y2是氢，卤素，低级烷基或苯基，R 3 Y 3是氢或低级烷基]。 R 8是氢或低级烷基; n为1或2的整数，或其盐。

2. 发明申请

US20060135401A1 Novel method of selecting immunosuppressant having little thrombocytopenic effect 审中-公开
标题翻译：选择具有很小血小板减少作用的免疫抑制剂的新方法
公开(公告)号：US20060135401A1
公开(公告)日：2006-06-22
申请号：US10519678
申请日：2003-07-07
申请人： Takao Fujimura , Hiroaki Mori , Katsuhiko Yoshizawa , Yoko Takata , Ichiro Aramori , Hideaki Matsuoka , Akira Unami , Takahisa Noto
发明人： Takao Fujimura , Hiroaki Mori , Katsuhiko Yoshizawa , Yoko Takata , Ichiro Aramori , Hideaki Matsuoka , Akira Unami , Takahisa Noto
IPC分类号： A61K38/17 , G01N33/567
CPC分类号： C12Q1/6897 , C12Q1/6883 , G01N33/5047 , G01N33/6869 , G01N33/6872 , G01N2333/55
摘要： The invention relates to a novel method for selecting an immunosuppressive agent with a less thrombocytopenia effect. According to the invention, a method for selecting an immunosuppressive agent which has a potent immunosuppressive activity but a lower thrombocytopenia effect, said method comprising measuring an IL-2 transcription inhibitory activity in a test cell in to which an IL-2 reporter gene has been introduced in the coexistence of an analyte, while measuring a GATA-1 transcription inhibitory activity in the test cell into which a GATA-1 reporter gene has been introduced in the coexistence of an analyte, and comparing both the transcription inhibitory activities, is provided.
摘要翻译：本发明涉及一种选择血小板减少作用较小的免疫抑制剂的新方法。根据本发明，一种选择具有有效的免疫抑制活性但较低的血小板减少症的免疫抑制剂的方法，所述方法包括测量IL-2转录抑制活性，其中IL-2报告基因已被在分析物共存的同时测量在分析物共存中引入了GATA-1报道基因的测试细胞中的GATA-1转录抑制活性，并比较两种转录抑制活性。

3. 发明申请

US20080076138A1 Novel Pd Marker for Histone Deacetylase Inhibitor 审中-公开
标题翻译：组蛋白脱乙酰酶抑制剂的新型Pd标记
公开(公告)号：US20080076138A1
公开(公告)日：2008-03-27
申请号：US11664422
申请日：2006-02-24
申请人： Hideaki Matsuoka , Yoshinori Ishii , Kaori Matsuda , Ichiro Aramori , Hiroaki Mori
发明人： Hideaki Matsuoka , Yoshinori Ishii , Kaori Matsuda , Ichiro Aramori , Hiroaki Mori
IPC分类号： G01N33/53 , C12Q1/02
CPC分类号： C12N9/99 , C12Q1/48 , G01N33/502
摘要： It is intended to provide a method for evaluating a pharmacological effect of a histone deacetylase (HDAC) inhibitor, comprising the steps of: (a) preparing a cell expressing CPSF5 protein; (b) contacting the cell with an HDAC inhibitor; (c) measuring the acetylation level of CPSF5 protein in the cell; and (d) comparing the acetylation level measured in the step (c) with the measured acetylation level of CPSF5 protein in a control cell that has not been contacted with the HDAC inhibitor.
摘要翻译：本发明旨在提供一种评价组蛋白脱乙酰酶（HDAC）抑制剂的药理作用的方法，包括以下步骤：（a）制备表达CPSF5蛋白的细胞; （b）使细胞与HDAC抑制剂接触; （c）测量细胞中CPSF5蛋白的乙酰化水平; 和（d）将步骤（c）中测量的乙酰化水平与未与HDAC抑制剂接触的对照细胞中测量的CPSF5蛋白的乙酰化水平进行比较。

4. 发明授权

US08065097B2 Energy usage display unit 有权
标题翻译：能源使用显示单位
公开(公告)号：US08065097B2
公开(公告)日：2011-11-22
申请号：US11937904
申请日：2007-11-09
申请人： Keiji Kato , Hideki Kitagawa , Hiroaki Mori , Yukihiro Suzuki
发明人： Keiji Kato , Hideki Kitagawa , Hiroaki Mori , Yukihiro Suzuki
IPC分类号： G01R21/00
CPC分类号： F24D19/1048 , F23N5/203 , F23N2025/22
摘要： An energy usage display unit for displaying energy usage of gas used for a water heater, water used for the water heater or electricity used in housing where the water heater is set. The energy usage display unit includes a clock section; a counting section for counting usage of gas, water or electricity; a memory section for storing a count value of usage counted by the counting section retroactive to past by a predetermined number with a predetermined time unit; a counting control section for writing the count value of usage at predetermined time; a display control section for reading one or both of the count value and a stored value in the memory section to prepare display data of usage; and a display section for displaying usage based on the display data prepared by the display control section.
摘要翻译：一种能量使用显示单元，用于显示用于热水器的气体的能量使用，用于热水器的水或在设置热水器的壳体中使用的电力。能量使用显示单元包括时钟部分; 用于计算天然气，水或电用量的计数部分; 存储部分，用于以预定时间单位存储由过去追溯到预定数量的计数部分计数的计数值; 计数控制部，用于在预定时间写入使用的计数值; 显示控制部分，用于读取存储器部分中的计数值和存储值中的一个或两个，以准备使用的显示数据; 以及显示部分，用于基于由显示控制部分准备的显示数据显示使用。

5. 发明申请

US20100255373A1 Method for preparing hydrogen absorbing electrode and nickel metal-hydride battery 有权
标题翻译：制备吸氢电极和镍氢电池的方法
公开(公告)号：US20100255373A1
公开(公告)日：2010-10-07
申请号：US12659099
申请日：2010-02-25
申请人： Toshinori Bandou , Kouichi Sakamoto , Hiroaki Mori , Kazuya Okabe , Shuichi Izuchi
发明人： Toshinori Bandou , Kouichi Sakamoto , Hiroaki Mori , Kazuya Okabe , Shuichi Izuchi
IPC分类号： H01M4/38 , H01B1/02
CPC分类号： H01M4/242 , C01B3/0057 , H01M2/022 , H01M2/263 , H01M4/26 , H01M4/364 , H01M4/383 , H01M4/48 , H01M4/52 , H01M10/30 , H01M10/345 , Y02E60/327
摘要： In a method for preparing a hydrogen absorbing electrode, a hydrogen absorbing alloy which contains a rare earth element as an alloy constituent and a transition metal element is immersed in an aqueous alkaline solution so that the saturation mass susceptibility is 1.0 to 6.5 emu/g of the hydrogen absorbing alloy. The hydrogen absorbing alloy is mixed through the immersing step with an oxide or hydroxide of a rare earth element wherein the oxide or hydroxide has as a main component at least one element selected from the group consisting of Dy, Ho, Er, Tm, Yb, and Lu. Then, a mixture of the hydrogen absorbing alloy and the oxide or hydroxide of the rare earth element is applied to form a desired shape.
摘要翻译：在制备吸氢电极的方法中，将含有作为合金成分的稀土元素的吸氢合金和过渡金属元素浸渍在碱性水溶液中，使得饱和质量敏感性为1.0〜6.5emu / g 吸氢合金。吸氢合金通过浸渍步骤与稀土元素的氧化物或氢氧化物混合，其中氧化物或氢氧化物作为主要成分选自Dy，Ho，Er，Tm，Yb，和卢。然后，施加吸氢合金和稀土元素的氧化物或氢氧化物的混合物以形成所需的形状。

6. 发明授权

US07771856B2 Energy output device and control method of energy output device 有权
标题翻译：能量输出装置及能量输出装置的控制方法
公开(公告)号：US07771856B2
公开(公告)日：2010-08-10
申请号：US10557579
申请日：2004-06-25
申请人： Naohiro Yoshida , Hiroaki Mori
发明人： Naohiro Yoshida , Hiroaki Mori
IPC分类号： H01M8/04
CPC分类号： H01M16/006 , B60K6/46 , B60L3/0046 , B60L3/0053 , B60L2260/56 , B60W10/28 , H01M8/04119 , H01M8/04223 , H01M8/04225 , H01M8/04228 , H01M8/04231 , H01M8/04302 , H01M8/04303 , H01M8/04373 , H01M8/0444 , H01M8/04559 , H01M8/04589 , H01M8/04679 , H01M8/04686 , H01M8/04955 , H01M2008/1095 , H01M2250/20 , Y02T10/6217 , Y02T90/32 , Y02T90/34
摘要： In a power supply device including a fuel cell unit with a stack of fuel cells or a fuel cell stack and a secondary battery, an intermittent drive mode is selected under a preset condition to receive power supply only from the secondary battery. The control procedure of the invention determines whether a temporary stop of the fuel cell stack or continuance of the stop of the fuel cell stack leads to potential performance deterioration of the fuel cell stack at a restart of the fuel cell unit. In response to estimation of the potential performance deterioration, the control procedure controls the power supply device to continue or start power generation of the fuel cell stack, regardless of selection of the intermittent drive mode under the preset condition.
摘要翻译：在包括具有燃料电池堆或燃料电池堆和二次电池的燃料电池单元的电源装置中，在预设条件下选择间歇驱动模式以仅从二次电池接收电力供应。本发明的控制程序确定燃料电池堆的临时停止或燃料电池堆的停止的持续是否导致在燃料电池单元的重启时燃料电池堆的潜在的性能劣化。响应于潜在性能劣化的估计，无论在预设条件下选择间歇驱动模式，控制程序控制电源装置继续或开始燃料电池堆的发电。

7. 发明申请

US20090130551A1 Nickel Metal-Hydride Battery 有权
标题翻译：镍金属氢化物电池
公开(公告)号：US20090130551A1
公开(公告)日：2009-05-21
申请号：US11988205
申请日：2006-06-30
申请人： Hiroaki Mori , Kouichi Sakamoto , Toshinori Bandou , Kazuya Okabe
发明人： Hiroaki Mori , Kouichi Sakamoto , Toshinori Bandou , Kazuya Okabe
IPC分类号： H01M4/36 , H01M4/48
CPC分类号： H01M4/242 , C01B3/0047 , C01B3/0057 , H01M2/26 , H01M4/383 , H01M10/345 , H01M2004/021 , Y02E60/327
摘要： A sealed nickel metal-hydride battery shows a high output density and an excellent cycle performance particularly in a cold atmosphere. In a nickel metal-hydride battery having a nickel electrode and a hydrogen absorbing electrode respectively as positive electrode and negative electrode, the hydrogen absorbing electrode is formed by making an conductive support carry hydrogen absorbing alloy powder of rare earth elements and non-rare earth elements including nickel and the saturation mass susceptibility of the hydrogen absorbing alloy powder is 2 to 6 emu/g while the rate at which the hydrogen absorbing electrode carries hydrogen absorbing alloy powder per unit area is 0.06 to 0.15 g/cm2.
摘要翻译：密封的镍氢电池显示出高的输出密度和优异的循环性能，特别是在寒冷的气氛中。在分别具有镍电极和吸氢电极的镍氢电池中，作为正极和负极，通过使导电性载体携带稀土元素和非稀土元素的吸氢合金粉末形成吸氢电极包括镍，并且吸氢合金粉末的饱和质量敏感性为2至6emu / g，而吸氢电极携带每单位面积吸氢合金粉末的速率为0.06至0.15g / cm 2。

8. 发明申请

US20080245157A1 Distortion Detector 失效
标题翻译：失真检测器
公开(公告)号：US20080245157A1
公开(公告)日：2008-10-09
申请号：US11663284
申请日：2005-09-30
申请人： Sigehiro Yosiuti , Shusaku Kawasaki , Hiroaki Mori , Yasunori Matsukawa , Yasunobu Kobayashi
发明人： Sigehiro Yosiuti , Shusaku Kawasaki , Hiroaki Mori , Yasunori Matsukawa , Yasunobu Kobayashi
IPC分类号： G01B7/16
CPC分类号： G01L5/101 , G01L1/2231
摘要： A strain detector includes a bridge circuit having at least two strain resistance elements, a substrate, a first fixed member, and a second fixed member. The substrate has a circuit portion electrically connected to the strain resistance elements. The strain resistance elements are arranged on the substrate. The first fixed member is fixed to a center of an area, where an outer periphery of the area is set at a position at which the strain resistance elements are arranged. The second fixed member is fixed outside the position, where the strain resistance elements are arranged at the substrate. A center of an axis of the first fixed member, a center of an axis of the second fixed member, and the center of the area are positioned on a straight line, and the first fixed member and the second fixed member are arranged on two mutually opposed surfaces of the substrate.
摘要翻译：应变检测器包括具有至少两个应变电阻元件的桥接电路，基板，第一固定部件和第二固定部件。基板具有电连接到应变电阻元件的电路部分。应变电阻元件布置在基板上。第一固定部件固定在区域的中心，该区域的外周设置在应变电阻元件的排列位置。第二固定部件固定在位于基板的应变电阻元件的位置之外。第一固定构件的轴线的中心，第二固定构件的轴的中心和区域的中心位于直线上，并且第一固定构件和第二固定构件相互布置基板的相对表面。

9. 发明申请

US20080075992A1 Fuel cell system and method of controlling the same fuel cell system 有权
公开(公告)号：US20080075992A1
公开(公告)日：2008-03-27
申请号：US11979613
申请日：2007-11-06
申请人： Nobuo Fujita , Kimihide Horio , Tadaichi Matsumoto , Naohiro Yoshida , Kenji Kurita , Shinya Sakaguchi , Hiroaki Mori
发明人： Nobuo Fujita , Kimihide Horio , Tadaichi Matsumoto , Naohiro Yoshida , Kenji Kurita , Shinya Sakaguchi , Hiroaki Mori
IPC分类号： H01M8/04
CPC分类号： H01M8/04253 , H01M8/04223 , H01M8/04225 , H01M8/04302 , H01M8/241 , H01M8/2457
摘要： The fuel cell system is provided which detects a freeze among specific components and portions thereof by evaluating various conditions upon starting operation of the fuel cell system. If a freeze is detected through those evaluations, the start of the system is prohibited in order to prevent some deterioration in the fuel cell system.

10. 发明申请

US20070054165A1 Energy output device and control method of energy output device 有权
标题翻译：能量输出装置及能量输出装置的控制方法
公开(公告)号：US20070054165A1
公开(公告)日：2007-03-08
申请号：US10557579
申请日：2004-06-25
申请人： Naohiro Yoshida , Hiroaki Mori
发明人： Naohiro Yoshida , Hiroaki Mori
IPC分类号： H01M8/04 , H01M8/24
CPC分类号： H01M16/006 , B60K6/46 , B60L3/0046 , B60L3/0053 , B60L2260/56 , B60W10/28 , H01M8/04119 , H01M8/04223 , H01M8/04225 , H01M8/04228 , H01M8/04231 , H01M8/04302 , H01M8/04303 , H01M8/04373 , H01M8/0444 , H01M8/04559 , H01M8/04589 , H01M8/04679 , H01M8/04686 , H01M8/04955 , H01M2008/1095 , H01M2250/20 , Y02T10/6217 , Y02T90/32 , Y02T90/34
摘要： In a power supply device including a fuel cell unit with a stack of fuel cells or a fuel cell stack and a secondary battery, an intermittent drive mode is selected under a preset condition to receive power supply only from the secondary battery. The control procedure of the invention determines whether a temporary stop of the fuel cell stack or continuance of the stop of the fuel cell stack leads to potential performance deterioration of the fuel cell stack at a restart of the fuel cell unit. In response to estimation of the potential performance deterioration, the control procedure controls the power supply device to continue or start power generation of the fuel cell stack, regardless of selection of the intermittent drive mode under the preset condition.
摘要翻译：在包括具有燃料电池堆或燃料电池堆和二次电池的燃料电池单元的电源装置中，在预设条件下选择间歇驱动模式以仅从二次电池接收电力供应。本发明的控制程序确定燃料电池堆的临时停止或燃料电池堆的停止的持续是否导致在燃料电池单元的重启时燃料电池堆的潜在的性能劣化。响应于潜在性能劣化的估计，无论在预设条件下选择间歇驱动模式，控制程序控制电源装置继续或开始燃料电池堆的发电。

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