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1. 发明授权

US06423332B1 Method and composition for deforming soft tissues 有权
标题翻译：软组织变形的方法和组成
公开(公告)号：US06423332B1
公开(公告)日：2002-07-23
申请号：US09579214
申请日：2000-05-26
申请人： Shawn T. Huxel , Ram L. Kataria , Joel S. Rosenblatt
发明人： Shawn T. Huxel , Ram L. Kataria , Joel S. Rosenblatt
IPC分类号： A61F1300
CPC分类号： A61L27/52
摘要： The present invention provides a composition and method for augmenting soft tissue, which composition includes a continuous phase that is a solid at temperatures less than about 10° C. or greater than about 30° C. and is a fluid at temperatures between about 10° C. and about 30° C., and which contains an aqueous solvent having dissolved therein a hydrogel and a dehydrating agent, and a discontinuous phase containing a plurality of hydrophilic hydrogel particles that are swellable in the aqueous solvent, that are not biodegradable for periods of time in excess of one year, and that have a hydrated diameter of greater than about 25 microns upon hydration by physiologic fluid; wherein the final volume of the hydrophilic hydrogel particles upon hydration by physiologic fluid is substantially the same as the initial volume of the composition used to augment the soft tissue.
摘要翻译：本发明提供了一种用于增加软组织的组合物和方法，该组合物包括在低于约10℃或大于约30℃的温度下为固体的连续相，并且为约10℃ 并且含有其中溶解有水凝胶和脱水剂的水性溶剂，以及包含在水性溶剂中可溶胀的多个亲水性水凝胶颗粒的不连续相，其不能在时间段内生物降解的时间超过一年，并且通过生理液体水合时具有大于约25微米的水合直径; 其中亲水性水凝胶颗粒在生理液体水合时的最终体积基本上与用于增加软组织的组合物的初始体积相同。

2. 发明申请

US20130060190A9 METHOD AND APPARATUS FOR REPAIRING A TENDON OR LIGAMENT 有权
公开(公告)号：US20130060190A9
公开(公告)日：2013-03-07
申请号：US12716724
申请日：2010-03-03
申请人： Leonard Gordon , Shawn T. Huxel , Mari Susan Truman , Alan B. Miller
发明人： Leonard Gordon , Shawn T. Huxel , Mari Susan Truman , Alan B. Miller
IPC分类号： A61M29/00 , A61B17/70
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/1146 , A61B17/3468 , A61B2017/0414 , A61B2017/044 , A61B2017/0472 , A61B2017/06057 , A61B2017/1103 , A61F2/0811 , A61M25/0023 , A61M29/00
摘要： A method and apparatus for reattaching the opposed ends of a member, such as a tendon, ligament or bone, during preparing and healing of the member using a surgical repair device that can be securely attached to the member and then safely guided through tortuous anatomy for reattachment and repair. The repair device further includes structural means so as to secure opposed ends of the member against separation during healing. Devices for aiding in the positioning of the surgical repair device are provided.

3. 发明申请

US20100237128A1 METHOD AND APPARATUS FOR DELIVERING A SHAPE MEMORY ARTICLE TO A SURGICAL SITE 有权
标题翻译：将形状记忆文章传送到外科手术的方法和装置
公开(公告)号：US20100237128A1
公开(公告)日：2010-09-23
申请号：US12708973
申请日：2010-02-19
申请人： Alan B. Miller , Shawn T. Huxel , Richard Thomas Briganti
发明人： Alan B. Miller , Shawn T. Huxel , Richard Thomas Briganti
IPC分类号： A61B17/068
CPC分类号： A61B17/068 , A61B17/0642 , A61B17/0644 , A61B17/0682 , A61B17/10 , A61B2017/0023 , A61B2017/00867 , A61B2017/0645 , A61B2090/034
摘要： The invention pertains to a method and apparatus for delivering an article formed of a shape memory alloy to a surgical implantation site.
摘要翻译：本发明涉及一种用于将由形状记忆合金形成的制品输送到手术植入部位的方法和装置。

4. 发明授权

US06503259B2 Expandable anastomotic device 有权
公开(公告)号：US06503259B2
公开(公告)日：2003-01-07
申请号：US09748311
申请日：2000-12-27
申请人： Shawn T. Huxel , John McAllen, III , David W. Overaker
发明人： Shawn T. Huxel , John McAllen, III , David W. Overaker
IPC分类号： A61B1708
CPC分类号： A61B17/115 , A61B17/0643 , A61B17/32053 , A61B2017/00725 , A61B2017/0641 , A61B2017/0647 , A61B2017/1107 , A61B2017/1132 , Y10S227/902 , Y10S411/923
摘要： A surgical fastening system includes a fastener having a plurality of individual fastener pairs each having a piercing element with a pin that pierces the tissue to be repaired and a receiver portion that interlocks with the pin of a corresponding piercing element. A fastener dispenser holds the piercing elements and receiver elements in relative juxtaposition and in a predetermined geometric configuration, such as a circle. After the tissues to be joined are positioned between the piercing and receiving elements held in the dispenser, the dispenser is adjusted to draw the elements together capturing the tissue therebetween. The dispenser then pushes the piercing elements through the tissue and into the receiving elements causing the elements to interlock. Because the anastomosed junction is formed by a plurality of independent pairs, the junction retains flexibility. When used to anastomose a tubular organ, the fastener allows radial expansion of the organ permitting peristalsis.

5. 发明授权

US5599852A Injectable microdispersions for soft tissue repair and augmentation 失效
标题翻译：用于软组织修复和增强的注射微分散体
公开(公告)号：US5599852A
公开(公告)日：1997-02-04
申请号：US324543
申请日：1994-10-18
申请人： Angelo G. Scopelianos , Steven C. Arnold , Rao S. Bezwada , Mark B. Roller , Shawn T. Huxel
发明人： Angelo G. Scopelianos , Steven C. Arnold , Rao S. Bezwada , Mark B. Roller , Shawn T. Huxel
IPC分类号： A61J1/05 , A61F2/02 , A61F2/12 , A61K9/00 , A61K9/107 , A61K47/34 , A61L27/00 , A61L27/18 , C08K5/15 , A61F2/00 , A61M5/00 , C08L3/00
CPC分类号： A61K9/0024 , A61K47/34 , A61L27/18
摘要： The present invention provides injectable, bioabsorbable microdispersions suitable for use as a soft tissue repair or augmentation material in animals comprising a fluid carrier that is a liquid polymer selected from the group consisting of liquid polymers and a particulate material. Additionally, the present invention also discloses methods of using these microdispersions for tissue augmentation and repair as well as kits which include prefilled containers to facilitate the use of these materials.
摘要翻译：本发明提供了适合用作动物中的软组织修复或增加材料的可注射的，生物可吸收的微分散体，其包含作为液体聚合物的流体载体，所述液体聚合物选自液体聚合物和颗粒材料。此外，本发明还公开了使用这些微分散体进行组织增强和修复的方法以及包括预装容器以便于使用这些材料的试剂盒。

6. 发明授权

US06846313B1 One-piece biocompatible absorbable rivet and pin for use in surgical procedures 失效
标题翻译：一体式生物相容性可吸收铆钉和针脚用于外科手术
公开(公告)号：US06846313B1
公开(公告)日：2005-01-25
申请号：US09667729
申请日：2000-09-22
申请人： Laurel L. Rogers , Mariann Sayer , David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski , Joseph R. Thomas
发明人： Laurel L. Rogers , Mariann Sayer , David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski , Joseph R. Thomas
IPC分类号： A61B17/58 , A61B17/68 , A61B17/56
CPC分类号： A61B17/68
摘要： A bioabsorbable rivet and pin fastener is formed as an elongated unit that may be used for anchoring, or for attachment of a fixation plate. The rivet has a head mechanically connected to two or more legs that extend generally distally from the head and may flex outwardly from a central rivet axis. The pin is integral with the rivet and oriented along the central axis by a connection such as a web or a plurality of braces, forming an integral, aligned, one-piece assembly that may, for example, be molded as a single piece. The connection breaks under force as the pin is driven into the rivet, so that the pin contacts internal surfaces of the legs and pushes the legs outward into frictional engagement with the surrounding bone. The one-piece assembly may be formed in a gated mold having a central pin with a relief passage that defines the braces between upper and lower portions of the rivet. The braces so formed at the weld line readily part from the mold, and are easily sheared when the pin is advanced during installation of the rivet.
摘要翻译：生物可吸收的铆钉和销紧固件形成为可用于锚定或用于附接固定板的细长单元。铆钉具有机械连接到两个或更多个腿的头部，该两个或多个腿部从头部大致向远侧延伸并且可以从中心铆钉轴线向外弯曲。该销与铆钉成一体并且通过诸如幅材或多个支架的连接件沿着中心轴线定向，形成整体的，对齐的整体式组件，其可以例如被模制成单件。当销被驱动到铆钉中时，连接断裂，使得销接触腿的内表面并向外推动腿与周围的骨摩擦接合。一体式组件可以形成在具有中心销的门控模具中，该中心销具有在铆钉的上部和下部之间限定支架的释放通道。在焊接线处形成的支架容易地与模具成一部分，并且在铆钉安装期间当销前进时容易剪切。

7. 发明授权

US06648811B2 Brachytherapy cartridge including absorbable and autoclaveable spacer 有权
标题翻译：近距离放射治疗药筒包括可吸收和可高压灭菌的间隔物
公开(公告)号：US06648811B2
公开(公告)日：2003-11-18
申请号：US09780437
申请日：2001-02-09
申请人： Thomas J. Sierocuk , Nicholas M. Popadiuk , John J. Karl , Shawn T. Huxel
发明人： Thomas J. Sierocuk , Nicholas M. Popadiuk , John J. Karl , Shawn T. Huxel
IPC分类号： A61M3600
CPC分类号： A61M37/0069 , A61N5/1007 , A61N5/1027 , A61N2005/101 , A61N2005/1023
摘要： The present invention is directed to a brachytherapy seed delivery system which includes a seed cartridge including a central channel, a plurality of brachytherapy seeds disposed within the central channel and a plurality of absorbable, dimensionally stable spacers disposed within the central channel. The present invention is further directed to a method of loading a brachytherapy seed delivery system including the steps of: providing a seed cartridge including a central channel, seeds and spacers as described above; connecting the brachytherapy seed cartridge to a brachytherapy needle including a cannula; and forcing the seeds out of the brachytherapy seed cartridge into the cannula. The present invention is further directed to an improved brachytherapy method including inserting the brachytherapy needle of the brachytherapy seed delivery system recited above into a human organ; and forcing the seeds and the spacer through the cannula of the brachytherapy needle and into the human organ.
摘要翻译：本发明涉及一种近距离放射治疗种子递送系统，其包括种子筒，其包括中央通道，设置在中心通道内的多个近距离放射治疗种子和设置在中心通道内的多个可吸收的尺寸稳定的间隔物。本发明还涉及一种装载近距离放射治疗种子递送系统的方法，包括以下步骤：提供包括如上所述的中心通道，种子和间隔物的种子仓; 将近距离放射治疗种子柱连接到包括插管的近距离放射治疗针; 并将种子从近距离放射治疗种子柱推入插管中。本发明进一步涉及一种改进的近距离放射治疗方法，包括将上述近距离放射治疗种子递送系统的近距离放射治疗针插入人体器官; 并迫使种子和间隔物通过近距离放射治疗针的插管进入人体器官。

8. 发明授权

US06335383B1 Microdispersions for coating surgical devices 失效
标题翻译：用于涂层外科手术器械的微分散体
公开(公告)号：US06335383B1
公开(公告)日：2002-01-01
申请号：US08806120
申请日：1996-03-07
申请人： Angelo G. Scopelianos , Steven C. Arnold , Rao S. Bezwada , Mark B. Roller , Shawn T. Huxel , Robert J. Tannhauser
发明人： Angelo G. Scopelianos , Steven C. Arnold , Rao S. Bezwada , Mark B. Roller , Shawn T. Huxel , Robert J. Tannhauser
IPC分类号： A61B1704
CPC分类号： C09D169/005 , A61K9/0024 , A61K47/34 , A61L17/145 , A61L27/18 , A61L27/34 , A61L31/10 , C09D167/04 , A61L27/58 , A61L27/54 , C08L67/04 , A61L31/148 , A61L31/16
摘要： The present invention provides surgical article and suture coated with bioabsorbable microdispersions which contains a fluid carrier that is a liquid polymer and a particular material.
摘要翻译：本发明提供涂覆有生物可吸收微分散体的外科用品和缝线，其包含作为液体聚合物和特定材料的流体载体。

9. 发明授权

US06221003B1 Brachytherapy cartridge including absorbable and autoclaveable spacer 有权
标题翻译：近距离放射治疗药筒包括可吸收和可高压灭菌的间隔物
公开(公告)号：US06221003B1
公开(公告)日：2001-04-24
申请号：US09360705
申请日：1999-07-26
申请人： Thomas J. Sierocuk , Nicholas M. Popadiuk , John J. Karl , Shawn T. Huxel
发明人： Thomas J. Sierocuk , Nicholas M. Popadiuk , John J. Karl , Shawn T. Huxel
IPC分类号： A61M3600
CPC分类号： A61M37/0069 , A61N5/1007 , A61N5/1027 , A61N2005/101 , A61N2005/1023
摘要： The present invention is directed to a brachytherapy seed delivery system which includes a seed cartridge including a central channel, a plurality of brachytherapy seeds disposed within the central channel and a plurality of absorbable, dimensionally stable spacers disposed within the central channel, wherein the absorbable, dimensionally stable spacers are interspersed between the brachytherapy seeds. The present invention is further directed to a method of loading a brachytherapy seed delivery system including the steps of: providing a seed cartridge including a central channel; placing at least two brachytherapy seeds into the central channel of the seed cartridge; placing at least one absorbable, dimensionally stable spacer in the central channel between the brachytherapy seeds; connecting the brachytherapy seed cartridge to a brachytherapy needle including a cannula; and forcing the seeds out of the brachytherapy seed cartridge into the cannula. The present invention is further directed to an improved brachytherapy method including the steps of: providing a seed cartridge including a central channel; placing at least two brachytherapy seeds into the central channel of the seed cartridge; placing at least one absorbable, dimensionally stable spacer in the central channel between the brachytherapy seeds; connecting the brachytherapy seed cartridge to a brachytherapy needle including a cannula; forcing the seeds out of the brachytherapy seed cartridge into the cannula; inserting the brachytherapy needle into a human organ; and forcing the seeds and the spacer through the cannula and into the human organ.
摘要翻译：本发明涉及近距离放射治疗种子输送系统，其包括种子筒，其包括中心通道，设置在中心通道内的多个近距离放射治疗种子和设置在中心通道内的多个可吸收的尺寸稳定的间隔物，其中可吸收，尺寸稳定的间隔物分散在近距离放射治疗种子之间。本发明还涉及一种装载近距离放射治疗种子递送系统的方法，包括以下步骤：提供包括中心通道的种子筒; 将至少两个近距离放射治疗种子放置到种子筒的中心通道中; 在近距离放射治疗种子之间的中央通道中放置至少一个可吸收的尺寸稳定的间隔物; 将近距离放射治疗种子柱连接到包括插管的近距离放射治疗针; 并将种子从近距离放射治疗种子柱推入插管中。本发明还涉及一种改进的近距离放射治疗方法，包括以下步骤：提供包括中心通道的种子筒; 将至少两个近距离放射治疗种子放置到种子筒的中心通道中; 在近距离放射治疗种子之间的中央通道中放置至少一个可吸收的尺寸稳定的间隔物; 将近距离放射治疗种子柱连接到包括插管的近距离放射治疗针; 迫使种子从近距离放射治疗种子筒进入插管; 将近距离放射治疗针插入人体器官; 并迫使种子和间隔物通过套管进入人体器官。

10. 发明申请

US20150201924A1 METHOD AND APPARATUS FOR REPAIRING A TENDON OR LIGAMENT 审中-公开
标题翻译：修理吊坠或吊坠的方法和装置
公开(公告)号：US20150201924A1
公开(公告)日：2015-07-23
申请号：US14451351
申请日：2014-08-04
申请人： Leonard Gordon , Shawn T. Huxel , Mari Susan Truman , Allen B. Miller
发明人： Leonard Gordon , Shawn T. Huxel , Mari Susan Truman , Allen B. Miller
IPC分类号： A61B17/04 , A61B17/34 , A61F2/08 , A61M29/00 , A61B17/11
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/1146 , A61B17/3468 , A61B2017/0414 , A61B2017/044 , A61B2017/0472 , A61B2017/06057 , A61B2017/1103 , A61F2/0811 , A61M25/0023 , A61M29/00
摘要： A method and apparatus for reattaching the opposed ends of a member, such as a tendon, ligament or bone, during preparing and healing of the member using a surgical repair device that can be securely attached to the member and then safely guided through tortuous anatomy for reattachment and repair. The repair device further includes structural means so as to secure opposed ends of the member against separation during healing. Devices for aiding in the positioning of the surgical repair device are provided.
摘要翻译：一种用于在使用可以牢固地附接到构件上然后通过曲折解剖结构安全地引导的手术修复装置来准备和愈合构件期间重新附接诸如腱，韧带或骨的构件的相对端的方法和装置，重新装修和修理。修复装置还包括结构装置，以便在愈合期间固定构件的相对端部以防分离。提供了用于辅助外科修复装置的定位的装置。

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