专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06407122B1 Amino-benzothiazole derivatives 失效
标题翻译：氨基苯并噻唑衍生物
公开(公告)号：US06407122B1
公开(公告)日：2002-06-18
申请号：US09554612
申请日：2000-06-01
申请人： Sergio Mantegani , Paolo Cremonesi , Mario Varasi , Carmela Speciale
发明人： Sergio Mantegani , Paolo Cremonesi , Mario Varasi , Carmela Speciale
IPC分类号： A61K31445
CPC分类号： C07D417/06
摘要： The present invention relates to amino-benzothiazole compounds of formula (I) wherein X, Y, Z and R1 are as defined in the specification, their pharmaceutically acceptable salts, processes for their preparation, pharmaceutical composition comprising such compounds and their use as neuroprotective agents.
摘要翻译：本发明涉及式（I）的氨基 - 苯并噻唑化合物，其中X，Y，Z和R 1如说明书中所定义，其药学上可接受的盐，其制备方法，包含这些化合物的药物组合物及其作为神经保护剂的用途。

2. 发明授权

US06765003B1 3-Arylsulfonyl-2 (substituted methyl) propanoic acid derivatives as matrix metalloproteinase inhibitors 失效
标题翻译： 3-芳基磺酰基-2（取代甲基）丙酸衍生物作为基质金属蛋白酶抑制剂
公开(公告)号：US06765003B1
公开(公告)日：2004-07-20
申请号：US10030681
申请日：2002-04-09
申请人： Sergio Mantegani , Francesca Abrate , Pierluigi Bissolino , Paolo Cremonesi , Ettore Perrone , Daniela Jabes
发明人： Sergio Mantegani , Francesca Abrate , Pierluigi Bissolino , Paolo Cremonesi , Ettore Perrone , Daniela Jabes
IPC分类号： A61K3133
CPC分类号： C07D213/70 , C07C317/46 , C07C323/65 , C07D233/72 , C07D233/84 , C07D235/28 , C07D239/38 , C07D239/56 , C07D249/12 , C07D257/04 , C07D277/36 , C07D285/125 , C07D285/135 , C07D333/34
摘要： Compounds which are 3-arylsulfonyl-2-methyl propanoic acid derivatives of formula (I): wherein X is HO—NH— or HO—, R1 is selected from phenyl, 4-chlorophenyl, 4-florophenyl, 4-cyanophenyl, benzamido (i.e., —NH—CO-Ph) and benzamido substituted on the terminal phenyl ring by C1-C4 alkyl, fluoro, chloro, cyano or C1-4 alkoxy; R2 is selected from (a) —S—Ar or —S—CH2—Ar wherein Ar is an aromatic moiety; (b) —O—Ar wherein Ar is as defined above; (c) —S-Het or —S—CH2-Het wherein Het is a heterocyclic ring; and (d) 2,5-dioxo-1-imidazolidinyl or 2,4-dioxo-1-imidazolinyl; and the pharmaceutically acceptable salts thereof; have potent and selective inhibitory activity against matrix metalloproteinases (MMPs) and can thus be used in the treatment and prevention of diseases mediated by MMPs.
摘要翻译：作为式（I）的3-芳基磺酰基-2-甲基丙酸衍生物的化合物：其中X是HO-NH-或HO-，R1选自苯基，4-氯苯基，4-氟苯基，4-氰基苯基，苯甲酰氨基（即-NH-CO-Ph）和在末端苯环上被C1-C4烷基，氟，氯，氰基或C1-4烷氧基取代的苯甲酰氨基; R2选自（a）-S-Ar或-S-CH2-Ar，其中Ar是芳族部分; （b）-O-Ar，其中Ar定义如上; （c）-S-Het或-S-CH2-Het，其中Het是杂环; 和（d）2,5-二氧代-1-咪唑烷基或2,4-二氧代-1-咪唑啉基; 及其药学上可接受的盐; 对基质金属蛋白酶（MMPs）具有有效和选择性的抑制活性，因此可用于治疗和预防由MMP介导的疾病。

3. 发明授权

US09749691B2 Client-side recommendations on one-way broadcast networks 有权
公开(公告)号：US09749691B2
公开(公告)日：2017-08-29
申请号：US14391836
申请日：2012-04-12
申请人： Paolo Cremonesi , Roberto Turrin
发明人： Paolo Cremonesi , Roberto Turrin
IPC分类号： H04N21/466 , H04N21/236 , H04N21/25 , H04N21/45 , H04N21/475 , H04N21/4788 , G06Q50/00 , H04N21/2665 , H04N21/434 , H04N21/442 , H04N21/462 , G06Q30/02
CPC分类号： H04N21/4668 , G06Q30/02 , H04N21/23614 , H04N21/252 , H04N21/2665 , H04N21/4348 , H04N21/442 , H04N21/44222 , H04N21/4532 , H04N21/4622 , H04N21/4667
摘要： A method and a client-side Recommender system on One-Way Broadcast Network includes at least a one-way channel connecting a broadcasting station to a set-top-box device of a first set of users, the set-top-box including a memory, a computation and driving unit for tracking the user activity, storing a user profile, generating and displaying a ranking of recommended media items, the ranking being determined by the computation unit through a recommender model stored on the memory. The system further includes a collaborative dual module, a first back-end module running on a auxiliary server connected to a two-way network and belonging to an auxiliary domain, this first back-end module leveraging external data sources to collect community based information on at least part of the media items, while the recommender model stored on the memory being a second front-end module, wherein the broadcasting station and the set-top-box device belong to a target domain.

4. 发明申请

US20150089524A1 CLIENT-SIDE RECOMMENDATIONS ON ONE-WAY BROADCAST NETWORKS 有权
标题翻译：单向广播网络的客户端建议
公开(公告)号：US20150089524A1
公开(公告)日：2015-03-26
申请号：US14391836
申请日：2012-04-12
申请人： Paolo Cremonesi , Roberto Turrin
发明人： Paolo Cremonesi , Roberto Turrin
IPC分类号： H04N21/466 , H04N21/442
CPC分类号： H04N21/4668 , G06Q30/02 , H04N21/23614 , H04N21/252 , H04N21/2665 , H04N21/4348 , H04N21/442 , H04N21/44222 , H04N21/4532 , H04N21/4622 , H04N21/4667
摘要： A method and a client-side Recommender system on One-Way Broadcast Network includes at least a one-way channel connecting a broadcasting station to a set-top-box device of a first set of users, the set-top-box including a memory, a computation and driving unit for tracking the user activity, storing a user profile, generating and displaying a ranking of recommended media items, the ranking being determined by the computation unit through a recommender model stored on the memory. The system further includes a collaborative dual module, a first back-end module running on a auxiliary server connected to a two-way network and belonging to an auxiliary domain, this first back-end module leveraging external data sources to collect community based information on at least part of the media items, while the recommender model stored on the memory being a second front-end module, wherein the broadcasting station and the set-top-box device belong to a target domain.
摘要翻译：单向广播网络上的方法和客户端推荐系统至少包括将广播台连接到第一组用户的机顶盒设备的至少一个单向频道，该机顶盒包括一个存储器，用于跟踪用户活动的计算和驱动单元，存储用户简档，生成和显示推荐媒体项目的排名，排序由计算单元通过存储在存储器上的推荐者模型来确定。该系统还包括协作双模块，第一后端模块，其运行在连接到双向网络并属于辅助域的辅助服务器上，该第一后端模块利用外部数据源来收集基于社区的信息至少部分媒体项目，而存储在存储器上的推荐模型是第二前端模块，其中广播站和机顶盒设备属于目标域。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式