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1. 发明授权

US09204926B2 Systems and methods for treating dysfunctions in the intestines and rectum that adapt to the anatomic form and structure of different individuals 有权
标题翻译：用于治疗肠和直肠功能障碍的系统和方法，其适应不同个体的解剖形式和结构
公开(公告)号：US09204926B2
公开(公告)日：2015-12-08
申请号：US14214880
申请日：2014-03-15
申请人： Scott H. West , John W. Gaiser , Patrick Rimroth , Larry C. Heaton
发明人： Scott H. West , John W. Gaiser , Patrick Rimroth , Larry C. Heaton
IPC分类号： A61B18/18 , A61B18/14 , A61B1/31 , A61B1/00 , A61B1/07 , A61B18/00 , A61B18/04 , A61B19/00
CPC分类号： A61B18/1477 , A61B1/00029 , A61B1/00066 , A61B1/00087 , A61B1/00094 , A61B1/00133 , A61B1/012 , A61B1/0661 , A61B1/07 , A61B1/31 , A61B1/32 , A61B18/1485 , A61B2018/00267 , A61B2018/00482 , A61B2018/00494 , A61B2018/00553 , A61B2018/00797 , A61B2018/0091 , A61B2018/00916 , A61B2018/046 , A61B2018/1425 , A61B2018/143 , A61B2018/1475 , A61B2090/3782 , A61B2218/007
摘要： A family of barrel structures is provided in a kit. Each barrel structure is differently sized and configured for advancement into anal canals of different anatomic morphologies. Instructions are provided for using the barrel structures to treat an individual. The instructions instruct assessing an anatomic morphology of an anal canal of an individual to be treated and selecting one of the barrel structures based upon the assessed anatomic morphology. Each barrel structure carries an electrode sized and configured to be coupled to a source of tissue ablation energy to be applied through the electrode to form a lesion. Each barrel structure includes a transparent side wall visualized by a direct line of sight from an end portion of the first barrel structure. The instructions instruct inserting the selected barrel structure into the anal canal and visualizing by the direct line of sight through the transparent side wall of the selected barrel structure the dentate line and the targeted tissue region. The instructions instruct, while visualizing, aligning the electrode in a desired location in the targeted tissue region above the dentate line, advancing the electrode to penetrate tissue at or near a sphincter, and applying energy through the electrode to create a lesion in the sphincter.
摘要翻译：套件中提供了一系列桶结构。每个桶体结构的尺寸和尺寸不同，可用于推进不同解剖形态的肛门运动。提供使用桶结构来处理个人的说明。说明书指导评估待治疗个体的肛管的解剖形态，并基于评估的解剖形态选择其中一个桶结构。每个桶结构都携带一个电极，其尺寸和构造被耦合到待通过电极施加的组织消融能量源以形成病变。每个桶结构包括通过来自第一桶结构的端部的直接视线可视化的透明侧壁。说明书指示将所选择的桶结构插入肛管并通过所选择的圆筒结构的透明侧壁通过直视线观察齿状线和目标组织区域。说明书指示，同时可视化，将电极对准在齿状线上方的目标组织区域中的期望位置，推进电极穿过括约肌中或附近的组织，以及通过电极施加能量以在括约肌中产生损伤。

2. 发明授权

US09107674B2 Systems and methods employing a guidewire for positioning and stabilizing external instruments deployed within the body 有权
公开(公告)号：US09107674B2
公开(公告)日：2015-08-18
申请号：US13854662
申请日：2013-04-01
申请人： John W. Gaiser , Scott H. West , David S. Utley , David Huynh
发明人： John W. Gaiser , Scott H. West , David S. Utley , David Huynh
IPC分类号： A61M25/00 , A61B18/14 , A61B1/00 , A61M25/02 , A61M16/04
CPC分类号： A61B18/1492 , A61B1/00154 , A61M16/0493 , A61M25/02 , A61M2025/024
摘要： Systems and methods for treating a tissue region employ an expandable structure projecting beyond the distal end of a catheter tube. A distal tail projects beyond the far end of the basket assembly. The distal tail includes a guidewire lumen that accommodates passage of a guidewire without threading the guidewire through the catheter tube.

3. 发明申请

US20140200480A1 DEVICES, SYSTEMS AND METHODS FOR TREATING TISSUE REGIONS OF THE BODY 审中-公开
公开(公告)号：US20140200480A1
公开(公告)日：2014-07-17
申请号：US14214872
申请日：2014-03-15
申请人： Scott H. West , David Huyhn , John W. Gaiser
发明人： Scott H. West , David Huyhn , John W. Gaiser
IPC分类号： A61B18/04 , A61B5/01
CPC分类号： A61B18/04 , A61B5/01 , A61B18/1492 , A61B2018/00029 , A61B2018/00214 , A61B2018/00267 , A61B2018/00797 , A61B2018/00821 , A61B2018/1425 , A61B2018/1475 , A61M2025/0037 , A61M2025/0096
摘要： Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.

4. 发明申请

US20100057080A1 Devices, systems and methods for treating tissue regions of the body 有权
标题翻译：用于治疗身体组织区域的装置，系统和方法
公开(公告)号：US20100057080A1
公开(公告)日：2010-03-04
申请号：US12590239
申请日：2009-11-04
申请人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick J. Rimroth
发明人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick J. Rimroth
IPC分类号： A61B18/14 , A61M29/00 , A61M25/02
CPC分类号： A61B18/1492 , A61B1/00087 , A61B1/0014 , A61B1/273 , A61B2018/00029 , A61B2018/00214 , A61B2018/00267 , A61B2018/00797 , A61B2018/00821 , A61B2018/1425 , A61B2018/1475
摘要： Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.
摘要翻译：用于治疗组织区域的改进的装置，系统和方法提供了在基于导管的器械的限制空间内安装各种功能组件的简单但可靠的方式。

5. 发明申请

US20140221996A1 DEVICES, SYSTEMS AND METHODS FOR TREATING TISSUE REGIONS OF THE BODY 审中-公开
标题翻译：用于治疗身体组织区域的装置，系统和方法
公开(公告)号：US20140221996A1
公开(公告)日：2014-08-07
申请号：US14256979
申请日：2014-04-20
申请人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick Rimroth
发明人： Scott H. West , John W. Gaiser , Robin Bek , David S. Utley , Patrick Rimroth
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B1/00087 , A61B1/0014 , A61B1/273 , A61B2018/00029 , A61B2018/00214 , A61B2018/00267 , A61B2018/00797 , A61B2018/00821 , A61B2018/1425 , A61B2018/1475
摘要： Improved devices, systems and methods for treating a tissue region provide straightforward, yet reliable ways for installing diverse functional components within the confined space of a catheter-based instrument.
摘要翻译：用于治疗组织区域的改进的装置，系统和方法提供了在基于导管的器械的限制空间内安装各种功能组件的简单但可靠的方式。

6. 发明申请

US20140018788A1 Devices and Systems for Carotid Body Ablation 审中-公开
标题翻译：颈动脉身体消融的装置和系统
公开(公告)号：US20140018788A1
公开(公告)日：2014-01-16
申请号：US13936121
申请日：2013-07-05
申请人： Zoar Jacob Engelman , Martin M. Grasse , Mark Gelfand , Charles Lennox , Marwan Abboud , Mark Leung , Howard Levin , Marat Fudim , Michael Brick Markham , Miriam H. Taimisto , Kenneth M. Martin , Robert Brommer , Scott H. West
发明人： Zoar Jacob Engelman , Martin M. Grasse , Mark Gelfand , Charles Lennox , Marwan Abboud , Mark Leung , Howard Levin , Marat Fudim , Michael Brick Markham , Miriam H. Taimisto , Kenneth M. Martin , Robert Brommer , Scott H. West
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1492 , A61B18/20 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00279 , A61B2018/00285 , A61B2018/00351 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00559 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/00839 , A61B2018/00863 , A61B2018/00875 , A61B2018/00898 , A61B2018/00904 , A61B2018/00982 , A61B2018/0212 , A61B2018/1861 , A61B2090/3784 , A61B2218/002 , A61N1/0551 , A61N1/36017 , A61N1/36053 , A61N1/36114
摘要： Methods and endovascular catheters for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via transmural carotid body ablation.
摘要翻译：用于评估和治疗患有交感神经介导的疾病的患者的方法和血管内导管通过减少化学传感器通过透壁颈动脉身体消融输入神经系统而涉及增加的外周化学反应和增强的交感神经紧张。

7. 发明授权

US07507234B2 Method for cryogenic tissue ablation 有权
标题翻译：低温组织消融的方法
公开(公告)号：US07507234B2
公开(公告)日：2009-03-24
申请号：US11420714
申请日：2006-05-26
申请人： David S. Utley , John Gaiser , Stuart D. Edwards , Scott H. West , Jay Qin
发明人： David S. Utley , John Gaiser , Stuart D. Edwards , Scott H. West , Jay Qin
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Methods of accessing and ablating abnormal epithelium tissue in an alimentary canal are provided. The methods can include steps of (i) inserting an operative element into an alimentary canal such that the proximate to a portion of the alimentary canal having tissue to be ablated; and (ii) using the operative element to apply cryogenic ablation to a site of abnormal tissue.
摘要翻译：提供了在消化道中获取和消融异常上皮组织的方法。所述方法可以包括以下步骤：（i）将操作元件插入消化道，使得靠近消化道的一部分具有要消融的组织; 和（ii）使用手术元件将低温消融应用于异常组织的部位。

8. 发明申请

US20090012421A1 Systems and methods for treating tissue regions of the body 审中-公开
标题翻译：用于治疗身体组织区域的系统和方法
公开(公告)号：US20090012421A1
公开(公告)日：2009-01-08
申请号：US12231924
申请日：2008-09-08
申请人： Robin Bek , John W. Gaiser , Scott H. West , Partick Rimroth
发明人： Robin Bek , John W. Gaiser , Scott H. West , Partick Rimroth
IPC分类号： A61B5/03 , A61B17/00
CPC分类号： A61B18/1492 , A61B5/037 , A61B5/06 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61B18/02 , A61B18/16 , A61B18/1815 , A61B18/20 , A61B2018/00029 , A61B2018/00214 , A61B2018/00244 , A61B2018/00267 , A61B2018/00488 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00744 , A61B2018/00821 , A61B2018/00863 , A61B2018/00982 , A61B2018/00994 , A61B2018/1422 , A61B2018/1425 , A61B2018/1465 , A61B2018/1475 , A61B2018/1807 , A61B2034/2046 , A61B2218/002
摘要： Systems and methods deploy a therapeutic or diagnostic element into contact with a body tissue region. The systems and methods can sense position of the therapeutic or diagnostic element relative to a targeted tissue region without direct or indirect visualization, by sensing fluid pressure in a fluid path having an outlet located at or near the therapeutic or diagnostic element. The systems and methods can also inflate the therapeutic or diagnostic element during use, while taking steps to avoid over-inflation and/or while dynamically monitoring the pressure conditions within the expanded element.
摘要翻译：系统和方法将治疗或诊断元件部署成与身体组织区域接触。系统和方法可以通过检测具有位于治疗或诊断元件处或附近的出口的流体路径中的流体压力来感测治疗或诊断元件相对于目标组织区域的位置，而不需要直接或间接可视化。系统和方法还可以在使用期间使治疗或诊断元件膨胀，同时采取步骤以避免过度膨胀和/或在动态监测扩张元件内的压力状况的同时。

9. 发明授权

US07422587B2 Systems and methods for treating tissue regions of the body 有权
标题翻译：用于治疗身体组织区域的系统和方法
公开(公告)号：US07422587B2
公开(公告)日：2008-09-09
申请号：US11114592
申请日：2005-04-26
申请人： Robin Bek , John W. Gaiser , Scott H. West , Patrick Rimroth
发明人： Robin Bek , John W. Gaiser , Scott H. West , Patrick Rimroth
IPC分类号： A61B18/18 , A61B19/00
CPC分类号： A61B18/1492 , A61B5/037 , A61B5/06 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61B18/02 , A61B18/16 , A61B18/1815 , A61B18/20 , A61B2018/00029 , A61B2018/00214 , A61B2018/00244 , A61B2018/00267 , A61B2018/00488 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00744 , A61B2018/00821 , A61B2018/00863 , A61B2018/00982 , A61B2018/00994 , A61B2018/1422 , A61B2018/1425 , A61B2018/1465 , A61B2018/1475 , A61B2018/1807 , A61B2034/2046 , A61B2218/002 , G06F19/00
摘要： Systems and methods deploy a therapeutic or diagnostic element into contact with a body tissue region. The systems and methods can sense position of the therapeutic or diagnostic element relative to a targeted tissue region without direct or indirect visualization, by sensing fluid pressure in a fluid path having an outlet located at or near the therapeutic or diagnostic element. The systems and methods can also inflate the therapeutic or diagnostic element during use, while taking steps to avoid over-inflation and/or while dynamically monitoring the pressure conditions within the expanded element.
摘要翻译：系统和方法将治疗或诊断元件部署成与身体组织区域接触。系统和方法可以通过检测具有位于治疗或诊断元件处或附近的出口的流体路径中的流体压力来感测治疗或诊断元件相对于目标组织区域的位置，而不需要直接或间接可视化。系统和方法还可以在使用期间使治疗或诊断元件膨胀，同时采取步骤以避免过度膨胀和/或在动态监测扩张元件内的压力状况的同时。

10. 发明授权

US6156027A Handle for catheter assembly with multifunction wire 有权
标题翻译：带多功能导线的导管组装手柄
公开(公告)号：US6156027A
公开(公告)日：2000-12-05
申请号：US382352
申请日：1999-08-25
申请人： Scott H. West
发明人： Scott H. West
IPC分类号： A61M25/00 , A61M25/01 , A61N1/05
CPC分类号： A61M25/0144 , A61M25/0136 , A61M25/0141 , A61M25/0147 , A61N1/0565 , A61B2018/00916 , A61B2018/00946 , A61B2018/00952
摘要： Mulifunction and radial deflection wires (66, 64) extend from a catheter shaft (8) and into a handle (4). The multifunction wire is pulled and pushed longitudinally and is rotated about its axis to change the stiffness of and to laterally deflect the tip portion (12). A curve size manipulator (32) on the handle body (24) moves the multifunction wire longitudinally but does not hinder its rotational movement. Rotation of a lateral deflection manipulator (38) on the handle causes the proximal end (70) of the multifunction wire to rotate about its own axis; the free longitudinal movement of the proximal end is unhindered. Any initial corkscrewing or other deflection of the tip portion can be removed at assembly by rotating the proximal end (68) of the radial deflection wire. The longitudinal movement of the manipulators can be limited by movable stops (120). The longitudinal positions of the abutment faces (126, 128) of the stops preferably change according to their longitudinal (distal or proximal) orientation.
摘要翻译：多功能和径向偏转线（66,64）从导管轴（8）延伸到手柄（4）中。多功能线被纵向拉动并推动并围绕其轴线旋转以改变尖端部分（12）的刚性并使其侧向偏转。手柄主体（24）上的曲线尺寸操纵器（32）纵向移动多功能线，但不妨碍其旋转运动。横向偏转操纵器（38）在手柄上的旋转使得多功能线的近端（70）绕其自身的轴线旋转; 近端的自由纵向运动是不受阻碍的。通过旋转径向偏转线的近端（68）可以在组装时去除尖端部分的任何初始的触控或其它偏转。操纵器的纵向移动可以通过可动止动件（120）来限制。挡块的邻接面（126,128）的纵向位置优选地根据其纵向（远侧或近端）取向而改变。

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