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1. 发明申请

US20140329914A1 Amphiphilic Peptides for Thoracic Air Leakage Occlusion 审中-公开
标题翻译：两亲性肽用于胸腔漏气闭塞
公开(公告)号：US20140329914A1
公开(公告)日：2014-11-06
申请号：US14239954
申请日：2012-08-31
申请人： Satoru Kobayashi , Satoshi Okada , Kentaro Takamura
发明人： Satoru Kobayashi , Satoshi Okada , Kentaro Takamura
IPC分类号： A61K47/42 , A61K31/397
CPC分类号： A61K47/42 , A61K31/397 , A61K38/10
摘要： Provided are compounds and methods useful for sealing air leaks in the thoracic cavity. Compounds and compositions of the invention comprise certain amphiphilic peptides, 8-200 amino acid residues long, that self-assemble spontaneously to form a gel in the presence of physiological pH and/or in the presence of a cation. In one embodiment, the peptide comprises a repeated sequence arginine-alanine-aspartic acid-alanine (RADA). Methods of the invention include a method of occluding a pulmonary air leak in a subject, comprising applying a compound of the invention to the site of a pulmonary air leak. The compounds and methods of the invention can be combined with other agents useful to treat cancer, inflammation, or infection.
摘要翻译：提供了用于密封胸腔漏气的化合物和方法。本发明的化合物和组合物包含长达8-200个氨基酸残基的某些两亲肽，其在生理pH和/或阳离子存在下自发组装以形成凝胶。在一个实施方案中，肽包含重复序列精氨酸 - 丙氨酸 - 天冬氨酸 - 丙氨酸（RADA）。本发明的方法包括阻塞受试者的肺部空气泄漏的方法，包括将本发明的化合物施用于肺部空气泄漏的部位。本发明的化合物和方法可以与可用于治疗癌症，炎症或感染的其它试剂组合。

2. 发明授权

US10576123B2 Tissue occluding agent comprising an IEIKIEIKIEIKI peptide 有权
公开(公告)号：US10576123B2
公开(公告)日：2020-03-03
申请号：US13122758
申请日：2009-10-06
申请人： Kentaro Takamura , Satoshi Gojo , Satoru Kobayashi
发明人： Kentaro Takamura , Satoshi Gojo , Satoru Kobayashi
IPC分类号： A61K38/10 , C07K7/08 , A61K38/16 , A61L31/14 , A61L31/04 , A61K31/7004 , A61K31/7016 , A61K38/08 , C07K7/06
摘要： There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a β-structure in aqueous solution in the presence of physiological pH and/or a cation.

3. 发明申请

US20110201541A1 TISSUE OCCLUDING AGENT 审中-公开
标题翻译：组织治疗代理
公开(公告)号：US20110201541A1
公开(公告)日：2011-08-18
申请号：US13122758
申请日：2009-10-06
申请人： Kentaro Takamura , Satoshi Gojo , Satoru Kobayashi
发明人： Kentaro Takamura , Satoshi Gojo , Satoru Kobayashi
IPC分类号： A61K38/00 , C07K7/08
CPC分类号： A61K38/10 , A61K31/7004 , A61K31/7016 , A61K38/08 , A61K38/16 , A61L31/047 , A61L31/148 , A61L2400/04 , A61L2430/36 , C07K7/06 , C07K7/08
摘要： There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like.The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a β-structure in aqueous solution in the presence of physiological pH and/or a cation.
摘要翻译：提供了可应用于包括人在内的大型哺乳动物的生物可吸收肽组织封闭剂，通过人工合成获得的肽组织封闭剂，以避免病毒感染等。组织封闭剂含有肽，其中肽是具有8-200个氨基酸残基的亲水性肽，亲水氨基酸和疏水性氨基酸交替键合，并且是在水溶液中显示“结构”的自组装肽在生理pH和/或阳离子存在下。

4. 发明授权

US09042447B2 Image coding apparatus and image coding method 有权
标题翻译：图像编码装置和图像编码方法
公开(公告)号：US09042447B2
公开(公告)日：2015-05-26
申请号：US13227369
申请日：2011-09-07
申请人： Satoru Kobayashi
发明人： Satoru Kobayashi
IPC分类号： H04N7/18 , H04N5/262 , H04N5/232 , H04N19/46 , H04N19/114
CPC分类号： H04N5/262 , H04N5/232 , H04N5/23248 , H04N5/23254 , H04N5/23264 , H04N19/114 , H04N19/46
摘要： There is provided an image coding apparatus for outputting an image stream in which random access and easy editing are possible without reducing encoding efficiency. The image coding apparatus sets, in the image stream, a picture in which the random access is possible based on camera control data or correlation between the images.
摘要翻译：提供了一种用于输出图像流的图像编码装置，其中随机访问和易于编辑是可能的，而不降低编码效率。图像编码装置基于相机控制数据或图像之间的相关性，在图像流中设置可以进行随机访问的图像。

5. 发明授权

US08982232B2 Image processing apparatus and image processing method 有权
标题翻译：图像处理装置和图像处理方法
公开(公告)号：US08982232B2
公开(公告)日：2015-03-17
申请号：US13543528
申请日：2012-07-06
申请人： Satoru Kobayashi
发明人： Satoru Kobayashi
IPC分类号： H04N5/235 , H04N5/238 , H04N5/272 , H04N5/357 , H04N5/365
CPC分类号： H04N5/272 , H04N5/357 , H04N5/3656
摘要： An image processing apparatus that, when combining a plurality of images, improves image quality by reducing noise in a region in which movement is detected, wherein a noise in the moving region is reduced by replacing the region in which movement is detected, with a low-noise image.
摘要翻译：一种图像处理装置，当组合多个图像时，通过降低检测到移动的区域中的噪声来提高图像质量，其中通过用检测到移动的区域替换来减少移动区域中的噪声，其中低 - 不好的形象。

6. 发明授权

US08287385B2 Game device, game processing method, information recording medium, and program 有权
标题翻译：游戏装置，游戏处理方法，信息记录介质和程序
公开(公告)号：US08287385B2
公开(公告)日：2012-10-16
申请号：US12441134
申请日：2007-02-01
申请人： Satoru Kobayashi
发明人： Satoru Kobayashi
IPC分类号： A63F13/00 , A63F9/24 , G06F17/00 , G06F19/00
CPC分类号： A63F13/56 , A63F13/10 , A63F2300/307 , A63F2300/6018 , A63F2300/636 , A63F2300/638 , A63F2300/64 , A63F2300/807
摘要： In a game device (200), a storage unit (201) stores a position of a player character, a position of an enemy character, and candidate positions for new enemy character appearance. A measuring unit (202) measures an elapsed time from the start of the game. The calculating unit (203) calculates a reference distance for determining a position where the new enemy character is to be produced based on the elapsed time measured by the measuring unit (202). The reference distance monotonically increases with respect to the elapsed time measured by the measuring unit (202). When a new enemy character is to be produced in the game, an appearance setting unit (204) selects from among the candidates stored in the storage unit (201) the candidate having a distance to the player character that is closest to the reference distance, and sets the selected position as the appearance position of the new enemy character.
摘要翻译：在游戏装置（200）中，存储单元（201）存储玩家角色的位置，敌人角色的位置和新敌人角色的候选位置。测量单元（202）测量从游戏开始起的经过时间。计算单元（203）基于由测量单元（202）测量的经过时间，计算用于确定要产生新的敌人角色的位置的参考距离。参考距离相对于由测量单元（202）测量的经过时间单调地增加。当在游戏中产生新的敌人角色时，出现设置单元（204）从存储在存储单元（201）中的候选者中选择距离参考距离最近的玩家角色的距离的候选者，并将所选位置设置为新敌人角色的出现位置。

7. 发明授权

US08259796B2 Image coding apparatus and image coding method 有权
标题翻译：图像编码装置和图像编码方法
公开(公告)号：US08259796B2
公开(公告)日：2012-09-04
申请号：US11760397
申请日：2007-06-08
申请人： Satoru Kobayashi
发明人： Satoru Kobayashi
IPC分类号： H04N7/12
CPC分类号： H04N19/152 , H04N19/124 , H04N19/137 , H04N19/14 , H04N19/149 , H04N19/172 , H04N19/176 , H04N19/61
摘要： An image coding apparatus calculates an image change rate with respect to input image data, predicts an average activity appropriate for a coding target picture that is included in the input image data based on the image change rate, and normalizes an activity using the predicted value of the average activity. Based on the normalized activity, the image coding apparatus performs a quantization of the image data.
摘要翻译：图像编码装置针对输入图像数据计算图像变化率，基于图像变化率预测适合于输入图像数据中包含的编码对象图像的平均活动，并使用预测值平均活动。基于标准化的动作，图像编码装置进行图像数据的量化。

8. 发明申请

US20110233482A1 CONDUCTIVE POWDER 审中-公开
标题翻译：导电粉
公开(公告)号：US20110233482A1
公开(公告)日：2011-09-29
申请号：US12671706
申请日：2008-08-04
申请人： Tetsuji Honjo , Satoru Kobayashi
发明人： Tetsuji Honjo , Satoru Kobayashi
IPC分类号： H01B1/08 , H01B1/20 , B05D5/12
CPC分类号： C09D5/29 , C01P2004/03 , C01P2006/40 , C08K3/22 , C08K9/02 , C09C1/0021 , C09C2200/1004 , C09D5/002 , C09D5/36 , C09D7/69 , C09D7/70 , C09D11/52
摘要： The present invention relates to an electrically conductive powder which has enough transparency for the use in the field of industrial design requiring expressions by colors, in particular, an electrically conductive powder which has superior dispersibility into solvents or polymer matrixes and gives conductivity even with low PWC.The present invention provides a transparent electrically conductive powder, comprising a first powder component that comprises:(a) a platelet-like aluminum oxide as a first substrate; and (b) a coating layer containing tungsten-doped, or tungsten- and phosphorus-doped, or phosphorus-doped tin oxide wherein the coating layer coats a surface of the first substrate.
摘要翻译：本发明涉及一种导电粉末，其具有足够的透明度用于需要颜色表示的工业设计领域，特别涉及一种在溶剂或聚合物基体中具有优异分散性并且即使在低PWC下也具有导电性的导电粉末。本发明提供一种透明导电粉末，其包括第一粉末成分，其包括：（a）作为第一基材的片状氧化铝; 和（b）包含钨掺杂或掺杂钨或磷的磷掺杂氧化锡的涂层，其中所述涂层涂覆在所述第一衬底的表面上。

9. 发明申请

US20100240634A1 Fluorene Compound and Pharmaceutical Use Thereof 有权
标题翻译：芴类化合物及其药物用途
公开(公告)号：US20100240634A1
公开(公告)日：2010-09-23
申请号：US12576605
申请日：2009-10-09
申请人： Takahisa Motomura , Hironobu Nagamori , Koichi Suzawa , Hirotsugu Ito , Toru Morita , Satoru Kobayashi , Hisashi Shinkai
发明人： Takahisa Motomura , Hironobu Nagamori , Koichi Suzawa , Hirotsugu Ito , Toru Morita , Satoru Kobayashi , Hisashi Shinkai
IPC分类号： A61K31/397 , C07C35/38 , A61K31/045 , C07D231/12 , A61K31/415 , C07D401/12 , A61K31/435 , A61P3/10 , A61P9/10 , A61P9/04 , A61P9/12 , A61P35/00
CPC分类号： C07D205/04 , A61K31/045 , A61K31/05 , A61K31/085 , A61K31/10 , A61K31/121 , A61K31/136 , A61K31/166 , A61K31/167 , A61K31/192 , A61K31/235 , A61K31/277 , A61K31/381 , A61K31/397 , A61K31/40 , A61K31/401 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4196 , A61K31/421 , A61K31/4245 , A61K31/425 , A61K31/435 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4439 , A61K31/4453 , A61K31/4523 , A61K31/5375 , C07C35/52 , C07C39/42 , C07C43/23 , C07C43/253 , C07C49/83 , C07C59/56 , C07C59/72 , C07C65/17 , C07C69/712 , C07C69/732 , C07C69/76 , C07C215/44 , C07C215/70 , C07C217/20 , C07C233/18 , C07C233/25 , C07C235/42 , C07C235/66 , C07C255/12 , C07C255/53 , C07C259/10 , C07C271/16 , C07C271/30 , C07C311/04 , C07C317/22 , C07C2603/18 , C07D207/04 , C07D211/06 , C07D213/30 , C07D213/56 , C07D231/12 , C07D239/26 , C07D249/08 , C07D257/04 , C07D263/32 , C07D271/06 , C07D271/10 , C07D275/02 , C07D295/08 , C07D295/18 , C07D295/192 , C07D333/22 , C07D401/06 , C07D401/12 , C07D403/12 , C07F7/081
摘要： The present invention provides an agent for the prophylactic or treatment of diabetes, diabetic complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, cardiac failure, cardiomyopathy, myocardial ischemia, brain ischemia, cerebral apoplexy, pulmonary hypertension, hyperlactacidemia, mitochondrial disease, mitochondrial encephalomyopathy or cancer, namely, a PDHK inhibitor and the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as defined in the specification.
摘要翻译：本发明提供了用于预防或治疗糖尿病，糖尿病并发症，胰岛素抵抗综合征，代谢综合征，高血糖症，血脂异常，动脉粥样硬化，心力衰竭，心肌病，心肌缺血，脑缺血，脑中风，肺动脉高压，高乳酸血症，线粒体疾病，线粒体性脑病或癌症，即PDHK抑制剂等。由下式[I]表示的化合物或其药学上可接受的盐或其溶剂化物：其中每个符号如说明书中所定义。

10. 发明授权

US07781602B2 Fluorinated cyclic compound, polymerizable fluoromonomer, fluoropolymer, resist material comprising the same, and method of forming pattern with the same 有权
标题翻译：含氟环状化合物，可聚合的含氟单体，含氟聚合物，包含它们的抗蚀剂材料，以及与其形成图案的方法
公开(公告)号：US07781602B2
公开(公告)日：2010-08-24
申请号：US11941433
申请日：2007-11-16
申请人： Haruhiko Komoriya , Shinichi Sumida , Katsunori Kawamura , Satoru Kobayashi , Satoru Miyazawa , Kazuhiko Maeda
发明人： Haruhiko Komoriya , Shinichi Sumida , Katsunori Kawamura , Satoru Kobayashi , Satoru Miyazawa , Kazuhiko Maeda
IPC分类号： C07D313/00 , C08F214/26 , C08F18/20
CPC分类号： G03F7/0397 , C07D307/93 , G03F7/0046 , G03F7/0392
摘要： The present invention relates to a novel fluorine-containing cyclic compound that is derived from a norbornadiene and hexafluoroacetone and has an oxacyclopentane structure. This compound may be represented by the following formula (1) or (2). Furthermore, the present invention relates to a fluorine-containing polymer compound prepared by a polymerization or copolymerization using this fluorine-containing cyclic compound or its derivative. By using such fluorine-containing polymer compound, it is possible to provide a superior resist material and a fine pattern forming process using the same.
摘要翻译：本发明涉及一种衍生自降冰片二烯和六氟丙酮并具有氧环戊烷结构的新型含氟环状化合物。该化合物可以由下式（1）或（2）表示。此外，本发明涉及通过使用该含氟环状化合物或其衍生物的聚合或共聚制备的含氟聚合物。通过使用这样的含氟聚合物化合物，可以提供优异的抗蚀剂材料和使用其的精细图案形成方法。

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