专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070134552A1 Multilayer ferritin array for bionanobattery 有权
标题翻译：多层铁蛋白阵列用于bionanobattery
公开(公告)号：US20070134552A1
公开(公告)日：2007-06-14
申请号：US11371575
申请日：2006-03-09
申请人： Sang-Hyon Chu , Sang Choi , Jae-Woo Kim , Peter Lillehei , Yeonjoon Park , Glen King , James Elliott
发明人： Sang-Hyon Chu , Sang Choi , Jae-Woo Kim , Peter Lillehei , Yeonjoon Park , Glen King , James Elliott
IPC分类号： H01M4/60 , H01M4/62
CPC分类号： H01M4/60 , H01M4/04 , H01M4/364 , H01M4/366 , H01M4/48 , H01M4/50 , H01M4/52
摘要： A thin-film electrode for a bio-nanobattery is produced by consecutively depositing arrays of a ferritin protein on a substrate, employing a spin self-assembly procedure. By this procedure, a first ferritin layer is first formed on the substrate, followed by building a second, oppositely-charged ferritin layer on the top of the first ferritin layer to form a bilayer structure. Oppositely-charged ferritin layers are subsequently deposited on top of each other until a desired number of bilayer structures is produced. An ordered, uniform, stable and robust, thin-film electrode material of enhanced packing density is presented, which provides optimal charge density for the bio-nanobattery.
摘要翻译：生物纳米电池的薄膜电极是通过使用自旋自组装方法在基片上连续沉积铁蛋白蛋白的阵列产生的。通过该过程，首先在衬底上形成第一铁蛋白层，随后在第一铁蛋白层的顶部上构建第二个相对充电的铁蛋白层以形成双层结构。随后将相对充电的铁蛋白层沉积在彼此的顶部，直到产生所需数量的双层结构。提出了一种有序，均匀，稳定和稳定的薄膜电极材料，提高了填充密度，为生物纳米电池提供了最佳的电荷密度。

2. 发明申请

US20070222034A1 Graded index silicon geranium on lattice matched silicon geranium semiconductor alloy 有权
标题翻译：分级指数硅锗在晶格匹配硅锗半导体合金上
公开(公告)号：US20070222034A1
公开(公告)日：2007-09-27
申请号：US11387086
申请日：2006-03-21
申请人： Yeonjoon Park , Sang Choi , Glen King , James Elliott , Diane Stoakley
发明人： Yeonjoon Park , Sang Choi , Glen King , James Elliott , Diane Stoakley
IPC分类号： H01L31/117
CPC分类号： C30B25/02 , C30B29/52 , H01L21/0242 , H01L21/0245 , H01L21/02502 , H01L21/02507 , H01L21/0251 , H01L21/02532
摘要： A lattice matched silicon germanium (SiGe) semiconductive alloy is formed when a {111} crystal plane of a cubic diamond structure SiGe is grown on the {0001} C-plane of a single crystalline Al2O3 substrate such that a orientation of the cubic diamond structure SiGe is aligned with a orientation of the {0001} C-plane. A lattice match between the substrate and the SiGe is achieved by using a SiGe composition that is 0.7223 atomic percent silicon and 0.2777 atomic percent germanium. A layer of Si1-xGex is formed on the cubic diamond structure SiGe. The value of X (i) defines an atomic percent of germanium satisfying 0.2277
摘要翻译：当晶体匹配的硅锗（SiGe）半导体合金在单晶Al 2 O 2的{0001} C面上生长时，形成立方晶体结构SiGe的{111}晶面，使得立方晶体结构SiGe的<110>取向与{0001} C面的<1,0，-1.0>取向对准。通过使用硅原子比为0.7223原子％和0.2777原子百分比的锗的SiGe组合来实现衬底和SiGe之间的晶格匹配。在立方晶体结构SiGe上形成一层Si 1-x Ge x S x。 X（i）的值定义了满足0.2277

3. 发明申请

US20070069195A1 Silicon germanium semiconductive alloy and method of fabricating same 有权
标题翻译：硅锗半导体合金及其制造方法
公开(公告)号：US20070069195A1
公开(公告)日：2007-03-29
申请号：US11242415
申请日：2005-09-27
申请人： Yeonjoon Park , Sang Choi , Glen King
发明人： Yeonjoon Park , Sang Choi , Glen King
IPC分类号： H01L31/109
CPC分类号： H01L31/1812 , H01L21/0242 , H01L21/02433 , H01L21/0245 , H01L21/02505 , H01L21/02516 , H01L21/02532 , H01L21/02609 , H01L31/1037 , Y02E10/50
摘要： A silicon germanium (SiGe) semiconductive alloy is grown on a substrate of single crystalline Al2O3. A {111} crystal plane of a cubic diamond structure SiGe is grown on the substrate's {0001} C-plane such that a orientation of the cubic diamond structure SiGe is aligned with a orientation of the {0001} C-plane. A lattice match between the substrate and the SiGe is achieved by using a SiGe composition that is 0.7223 atomic percent silicon and 0.2777 atomic percent germanium.
摘要翻译：硅锗（SiGe）半导体合金生长在单晶Al 2 O 3 3的衬底上。立方金刚石结构SiGe的{111}晶面在衬底的{0001} C面上生长，使得立方晶体结构SiGe的<110>取向与<1,0,1.0> {0001} C面的取向。通过使用硅原子比为0.7223原子％和0.2777原子百分比的锗的SiGe组合来实现衬底和SiGe之间的晶格匹配。

4. 发明申请

US20090170748A1 Plasmid mediated supplementation for treating chronically ill subjects 有权
标题翻译：质粒介导的补充治疗慢性病患者
公开(公告)号：US20090170748A1
公开(公告)日：2009-07-02
申请号：US11726291
申请日：2007-03-21
申请人： Ruxandra Draghia-Akli , Robert H. Carpenter , Douglas R. Kern , Robert J. Schwartz , Glen King , Kevin Hahn , Malcolm K. Brenner
发明人： Ruxandra Draghia-Akli , Robert H. Carpenter , Douglas R. Kern , Robert J. Schwartz , Glen King , Kevin Hahn , Malcolm K. Brenner
IPC分类号： A61K38/00 , A61P7/06
CPC分类号： A61K38/25 , A61K48/00
摘要： The present invention pertains to compositions and methods for plasmid-mediated supplementation. The compositions and methods are useful for treating anemia and other effects that are commonly associated in cancer bearing animals. Overall, the embodiments of the invention can be accomplished by delivering an effective amount of a nucleic acid expression construct that encodes a GHRH or functional biological equivalent thereof into a tissue of an animal and allowing expression of the encoded gene in the animal. For example, when such a nucleic acid sequence is delivered into the specific cells of the animal tissue specific constitutive expression is achieved.
摘要翻译：本发明涉及用于质粒介导的补充的组合物和方法。组合物和方法可用于治疗贫血和通常与携带癌症的动物相关的其它作用。总的来说，本发明的实施方案可以通过将有效量的编码GHRH或其功能生物等价物的核酸表达构建体递送到动物的组织中并允许编码的基因在动物中表达来实现。例如，当这种核酸序列被递送到动物组织的特定细胞中时，实现了特异性组成型表达。

5. 发明授权

US08178504B2 Gene therapy expression of GHRH for increasing RBC count in subjects 有权
标题翻译：基因治疗GHRH表达增加受试者的RBC计数
公开(公告)号：US08178504B2
公开(公告)日：2012-05-15
申请号：US11726291
申请日：2007-03-21
申请人： Ruxandra Draghia-Akli , Robert H. Carpenter , Douglas R. Kern , Robert J. Schwartz , Glen King , Kevin Hahn , Malcolm K. Brenner
发明人： Ruxandra Draghia-Akli , Robert H. Carpenter , Douglas R. Kern , Robert J. Schwartz , Glen King , Kevin Hahn , Malcolm K. Brenner
IPC分类号： A61K48/00 , A01N63/00 , A01N65/00
CPC分类号： A61K38/25 , A61K48/00
摘要： The present invention pertains to compositions and methods useful for treating anemia and other effects that are commonly associated in cancer bearing animals. The invention is accomplished by delivering an effective amount of a nucleic acid expression construct that encodes a GHRH or functional biological equivalent thereof into a tissue of an animal and allowing expression of the encoded gene in the animal.
摘要翻译：本发明涉及可用于治疗贫血的组合物和方法以及通常与携带癌症的动物相关的其它作用。本发明通过将有效量的编码GHRH或其功能生物等价物的核酸表达构建体递送到动物的组织中并允许编码的基因在动物中表达来实现。

6. 发明申请

US20080026079A1 Calcium aluminosilicate pharmaceutical 审中-公开
标题翻译：硅铝酸钙制药
公开(公告)号：US20080026079A1
公开(公告)日：2008-01-31
申请号：US11821983
申请日：2007-06-26
申请人： Robert Carpenter , Kevin Hahn , Glen King , Melissa Endicott
发明人： Robert Carpenter , Kevin Hahn , Glen King , Melissa Endicott
IPC分类号： A61K33/06 , A61P1/12
CPC分类号： A61K33/06 , A61K9/0095 , A61K33/00 , A61K33/26 , A61K33/32 , A61K45/06
摘要： A composition and method of treating symptoms of diarrhea that utilize administering an effective amount of an isolated calcium aluminosilicate anti-diarrheal (“CASAD”), wherein the isolated CASAD is substantially free from T4-dioxin and toxic heavy metal contamination, waiting a period of time; and repeating the administration of the composition until the symptoms of diarrhea are mitigated. The symptoms of diarrhea may be associated with chronic or infectious diseases, inflammatory proteins, treatment using drugs, or treatment using a chemotheraputic agent in a subject in need of treatment. The isolated CASAD is capable of binding inflammatory proteins, drug metabolites, and chemotherapeutic agents. The isolated CASAD can be administered in any suitable form, such as in tablet, powder, or suspension form, and can be administered by any suitable route, such as orally.
摘要翻译：一种治疗腹泻症状的组合物和方法，其使用有效量的分离的硅铝酸钙抗腹泻（“CASAD”），其中分离的CASAD基本上不含T4-二恶英和有毒的重金属污染，等待一段时间时间; 并重复施用组合物，直到缓解腹泻症状。腹泻的症状可能与慢性或感染性疾病，炎性蛋白质，使用药物治疗或使用化学治疗剂治疗需要治疗的受试者有关。分离的CASAD能够结合炎症蛋白，药物代谢物和化学治疗剂。分离的CASAD可以任何合适的形式施用，例如以片剂，粉末或悬浮液形式施用，并且可以通过任何合适的途径，例如口服施用。

7. 发明授权

US07241744B2 Treating anemia in subjects by administration of plasmids encoding growth hormone releasing hormone 有权
标题翻译：通过施用编码生长激素释放激素的质粒治疗受试者的贫血
公开(公告)号：US07241744B2
公开(公告)日：2007-07-10
申请号：US10315907
申请日：2002-12-10
申请人： Ruxandra Draghia-Akli , Robert H. Carpenter , Douglas R. Kern , Robert J. Schwartz , Glen King , Kevin Hahn , Malcolm K. Brenner
发明人： Ruxandra Draghia-Akli , Robert H. Carpenter , Douglas R. Kern , Robert J. Schwartz , Glen King , Kevin Hahn , Malcolm K. Brenner
IPC分类号： A01N43/04 , A61K31/70 , A01N63/00 , A01N65/00 , C07H21/02 , C07H21/04 , A61K38/24 , C07K1/00 , C07K17/00
CPC分类号： A61K38/25 , A61K48/00
摘要： The present invention pertains to compositions and methods for plasmid-mediated supplementation. The compositions and method are useful for retarding the growth of the tumor, and retarding cachexia, wasting, anemia and other effects that are commonly associated in cancer bearing animals. Overall, the embodiments of the invention can be accomplished by delivering an effective amount of a nucleic acid expression construct that encodes a GHRH or functional biological equivalent thereof into a tissue of an animal and allowing expression of the encoded. gene in the animal. For example, when such a nucleic acid sequence is delivered into the specific cells of the tissue specific constitutive expression is achieved.
摘要翻译：本发明涉及用于质粒介导的补充的组合物和方法。组合物和方法可用于延缓肿瘤的生长，并缓解通常与携带癌症的动物相关的恶病质，浪费，贫血和其它作用。总的来说，本发明的实施方案可以通过将有效量的编码GHRH或其功能生物等价物的核酸表达构建体递送到动物的组织中并允许编码的表达来实现。基因在动物体内。例如，当这样的核酸序列被递送到组织的特定细胞中时，实现了特异性组成型表达。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式