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    • 8. 发明授权
    • Method for preparing porous shells or gels from glass particles
    • 从玻璃颗粒制备多孔壳或凝胶的方法
    • US06358531B1
    • 2002-03-19
    • US09241492
    • 1999-02-01
    • Delbert E. DaySamuel D. Conzone
    • Delbert E. DaySamuel D. Conzone
    • A61K914
    • A61K9/501A61K9/1611C03C1/006C03C11/002C03C12/00Y10S977/775Y10S977/906
    • A method is provided for preparing shells, concentric shells or porous, homogenous gels from alkali borate glass particles at low temperatures (i.e. room temperature or less than above 100° C.). The alkali borate glass particles contain one or more cations such as aluminum which react with an aqueous solution containing an anion such as hydroxide to form an aqueous insoluble material having a solubility limit of less than about 0.01 wt. percent. The resulting shells or gels may be used in many different applications such as a filler in resins, as filters, precursors for nano-sized powders, as thin surface films or catalyst support media. The resulting shells or gels may also have a chemotherapeutic drug added thereto, following which the resulting product is administered to a mammal and the insoluble material is dissolved form the product in vivo through administration of chelating agent.
    • 提供了一种在低温(即室温或低于100℃)下从碱金属硼酸盐玻璃颗粒制备壳,同心圆壳或多孔同质凝胶的方法。 碱金属硼酸盐玻璃颗粒含有一种或多种阳离子例如铝,其与含有阴离子如氢氧化物的水溶液反应,形成溶解度极限小于约0.01重量%的水不溶性物质。 百分。 所得的壳或凝胶可用于许多不同的应用,例如树脂中的填料,作为过滤器,用于纳米尺寸粉末的前体,作为薄表面膜或催化剂载体介质。 所得的壳或凝胶也可以具有加入其中的化学治疗药物,随后将所得产物施用于哺乳动物,并且通过施用螯合剂在体内将不溶性物质从体内溶解。