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1. 发明申请

US20120116300A1 ACTIVATION AND DELIVERY DEVICES FOR THERAPEUTIC COMPOSITIONS 审中-公开
标题翻译：用于治疗组合物的活化和递送装置
公开(公告)号：US20120116300A1
公开(公告)日：2012-05-10
申请号：US12998854
申请日：2009-12-09
申请人： Samuel D. Banks, JR. , Katie A. Bush , Thomas D. Egan , Braden C. Fleming , Martha M. Murray , Matthew Palmer , David M. Skinlo , Thomas P. Weisel , Emma Wright
发明人： Samuel D. Banks, JR. , Katie A. Bush , Thomas D. Egan , Braden C. Fleming , Martha M. Murray , Matthew Palmer , David M. Skinlo , Thomas P. Weisel , Emma Wright
IPC分类号： A61M5/00
CPC分类号： A61K9/0024 , A61F2/08 , A61F2002/0086 , A61F2250/0068 , A61L27/54 , A61L29/16 , A61L31/16
摘要： Devices and methods for activating a therapeutic composition, delivering a therapeutic composition to a specific region or tissue in a body, and containing a therapeutic composition within a body cavity are disclosed herein. In one embodiment, a therapeutic capsule is shown having an outer element defining an interior chamber and including a matrix disposed therein and wherein the interior chamber is elongated along a chamber axis.
摘要翻译：本文公开了用于激活治疗组合物，将治疗组合物递送至体内特定区域或组织，以及在体腔内含有治疗组合物的装置和方法。在一个实施例中，治疗胶囊被示出具有限定内部腔室的外部元件并且包括设置在其中的矩阵，并且其中内部腔室沿着腔室轴线是细长的。

2. 发明授权

US06286746B1 Fused loop of filamentous material and apparatus for making same 失效
标题翻译：丝状材料的熔融回路及其制造装置
公开(公告)号：US06286746B1
公开(公告)日：2001-09-11
申请号：US09118395
申请日：1998-07-17
申请人： Thomas D. Egan , Paul V. Fenton, Jr.
发明人： Thomas D. Egan , Paul V. Fenton, Jr.
IPC分类号： B23K106
CPC分类号： B29C65/08 , A61B17/0487 , A61B17/06166 , A61B17/320068 , A61B2017/00526 , A61B2017/0454 , A61B2017/0619 , A61L17/00 , B29C66/1122 , B29C66/5261 , B29C66/69 , B29C66/71 , B29C66/73921 , B29C66/80 , B29C66/81422 , B29C66/81423 , B29C66/81433 , B29C66/81463 , B29C66/8322 , B29K2023/12 , B29K2067/043 , B29K2077/00 , B29K2101/12 , B29L2031/709 , B29L2031/7096 , B29L2031/7102 , B29C65/00 , B29K2067/00
摘要： A fused loop of an elongated material, such as a surgical suture, and apparatus for making the loop. Portions of one or more segments to be joined together are fused in a welding process to form a welded joint. The shear area of the fused portion of the joint determines the strength of the joint and is thus preferably relatively large. Various configurations for the welding apparatus facilitate the creation of relatively large fused portions of the joint by maximizing contact between at least one of the welding members of the apparatus and at least one of the segments to be joined.
摘要翻译：诸如手术缝合线的细长材料的熔合环和用于制造环的装置。要焊接在一起的一个或多个部分的部分在焊接过程中熔合以形成焊接接头。接头的熔融部分的剪切面积确定接头的强度，因此优选地相对较大。用于焊接设备的各种构造通过使设备的至少一个焊接构件和待接合的区段中的至少一个之间的接触最大化来促进形成接头的相对大的熔融部分。

3. 发明授权

US6106545A Suture tensioning and fixation device 失效
标题翻译：缝合张紧固定装置
公开(公告)号：US6106545A
公开(公告)日：2000-08-22
申请号：US61472
申请日：1998-04-16
申请人： Thomas D. Egan
发明人： Thomas D. Egan
IPC分类号： A61B17/04 , A61B17/06
CPC分类号： A61B17/0487 , A61B2017/0464 , A61B2017/0496 , A61B2017/06038 , A61B2017/0619
摘要： A suture tensioning and fixation device comprises a suture thread and a suture retaining element. The retaining element has a first suture thread engaging portion on the first end, a second suture thread engaging portion opposite the first suture thread engaging portion, and a third, substantially centrally located suture thread engaging portion. The retaining element is adapted such that segments of the suture thread can be interwoven between the suture thread engaging portions of the retaining element. The suture thread engaging portions of the retaining element are adapted to frictionally hold the interwoven segments of suture thread. Localized melting of the retaining element where it contacts the suture thread segments establishes a weld and bonds the suture thread to the retaining element in a knotless joint.
摘要翻译：缝合线张紧和固定装置包括缝合线和缝线保持元件。保持元件具有在第一端上的第一缝合线接合部分，与第一缝合线接合部分相对的第二缝合线接合部分以及第三基本中心定位的缝合线接合部分。保持元件适于使得缝合线的段可以在保持元件的缝合线接合部分之间交织。保持元件的缝合线接合部分适于摩擦地保持缝合线的交织部分。保持元件与缝合线段接触的局部熔化建立了焊缝，并将缝合线结合到无节结合的保持元件上。

4. 发明授权

US5626563A Irrigation system with tubing cassette 失效
标题翻译：带油管的灌溉系统
公开(公告)号：US5626563A
公开(公告)日：1997-05-06
申请号：US371011
申请日：1995-01-11
申请人： Larry H. Dodge , Ulf B. Dunberger , Thomas D. Egan , Harpreet Kaur , Kenneth E. Merte
发明人： Larry H. Dodge , Ulf B. Dunberger , Thomas D. Egan , Harpreet Kaur , Kenneth E. Merte
IPC分类号： A61B1/00 , A61M1/00 , A61M3/02 , A61M31/00 , A61M39/28 , F04B43/12
CPC分类号： F04B43/1253 , A61M1/0058 , F04B43/1284 , A61M2205/12 , A61M2205/3344 , A61M39/28
摘要： The present invention provides a tubing set in cassette form and an irrigation system employing the cassette and tubing set for use in endoscopic procedures. The tubing set includes a generally arcuate cassette which is inserted into the pump housing to effect a change in tubing sets between procedures. A valve assembly and flattened tubing segment are preferably used to provide pressure control/relief in the tubing set/irrigation system. Also provided in combination with the preferred cassette is a fitting for coupling a pressure monitoring line with pressure monitoring equipment in the irrigation system.
摘要翻译：本发明提供了一种盒形式的管道装置以及采用用于内窥镜程序的盒和管道组件的灌溉系统。管道组件包括大体上弓形的盒，其插入到泵壳体中以在过程之间实现管道组的改变。阀组件和扁平管段优选用于在管道组/灌溉系统中提供压力控制/释放。还与优选的盒一起提供的是用于将压力监测管线与灌溉系统中的压力监测设备耦合的配件。

5. 发明授权

US5403277A Irrigation system with tubing cassette 失效
标题翻译：带油管的灌溉系统
公开(公告)号：US5403277A
公开(公告)日：1995-04-04
申请号：US3475
申请日：1993-01-12
申请人： Larry H. Dodge , H. Aaron Christmann , Ulf B. Dunberger , Thomas D. Egan , James R. Watts
发明人： Larry H. Dodge , H. Aaron Christmann , Ulf B. Dunberger , Thomas D. Egan , James R. Watts
IPC分类号： A61M1/00 , A61M39/28 , F04B43/12
CPC分类号： F04B43/1284 , A61M1/0058 , F04B43/1253 , A61M2205/12 , A61M2205/3344 , A61M39/28 , Y10S128/12
摘要： An irrigation system for use in endoscopic procedures for maintaining and controlling flow of irrigation fluid to an internal body irrigation site. The system includes a tubing set comprising inflow and outflow lines and a cassette, and an fluid control module comprising a race and a pumping mechanism that squeezes the inflow line of the tubing set against the race to pump fluid to the irrigation site. The cassette includes a through opening exposing a portion of the inflow line to the race and pumping mechanism so that the cassette merely holds the inflow line in alignment with the pumping mechanism but is not required to resist the compressive force of the pumping mechanism. The cassette may include a second through opening exposing a portion of the outflow line to a valve mechanism to regulate pressure independently of the pump mechanism, and rib-or-groove alignment mechanism to align the inflow line with the pumping mechanism and the outflow line with the valve mechanism.
摘要翻译：一种用于内窥镜程序的灌溉系统，用于维持和控制灌溉流体流入内部灌溉部位。该系统包括一个包括流入和流出管线和一个盒子的管道组件，以及一个流体控制模块，它包括一个滚道和一个泵送机构，该机构挤压管道组件的流入管路抵抗该座圈，以将流体泵入灌溉部位。所述盒包括将所述流入线的一部分暴露于所述座圈和泵送机构的通孔，使得所述盒仅保持所述流入线与所述泵送机构对准，但不需要抵抗所述泵送机构的压缩力。盒可以包括第二通孔，其将流出管线的一部分暴露于阀机构以独立于泵机构调节压力，以及肋或槽对准机构，以将流入管线与泵送机构和流出管线对准，阀门机构。

6. 发明申请

US20080188936A1 SYSTEM AND METHOD FOR REPAIRING TENDONS AND LIGAMENTS 审中-公开
标题翻译：修复吊坠和吊坠的系统和方法
公开(公告)号：US20080188936A1
公开(公告)日：2008-08-07
申请号：US12025449
申请日：2008-02-04
申请人： Robert J. Ball , Thomas D. Egan , Paul V. Fenton , Kevin L. Ohashi , Dale R. Peterson , Peter Sorenson , Douglas Snell , John Yannone , Patrick Fenton
发明人： Robert J. Ball , Thomas D. Egan , Paul V. Fenton , Kevin L. Ohashi , Dale R. Peterson , Peter Sorenson , Douglas Snell , John Yannone , Patrick Fenton
IPC分类号： A61F2/08
CPC分类号： A61F2/08 , A61B17/1146 , A61B2017/0404 , A61B2017/0417 , A61B2017/0496 , A61F2/0063
摘要： An implant and method for the repair of a tendon or a ligament along at least one load direction. The implant includes at least one first anchor portion and at least one tension member oriented along a load direction. The first anchor portion preferably has a larger surface area of engagement with the tendon or ligament to spread loads across more tissue. The tension member is preferably secured to the first anchor portion with an overlapping attachment. Tension on the tension member is preferably adjustable by the surgeon.
摘要翻译：用于沿至少一个负载方向修复腱或韧带的植入物和方法。植入物包括至少一个第一锚定部分和沿着负载方向定向的至少一个张紧构件。第一锚固部分优选地具有与腱或韧带接合的更大的表面积，以将载荷跨越更多的组织。张紧构件优选地以重叠的附接件固定到第一锚固部分。张力构件上的张力优选由外科医生调节。

7. 发明授权

US5941901A Bondable expansion plug for soft tissue fixation 失效
标题翻译：用于软组织固定的粘结膨胀塞
公开(公告)号：US5941901A
公开(公告)日：1999-08-24
申请号：US61604
申请日：1998-04-16
申请人： Thomas D. Egan
发明人： Thomas D. Egan
IPC分类号： A61B17/56 , A61B17/04 , A61B19/00 , A61F2/02 , A61F2/08
CPC分类号： A61F2/0811 , A61B17/0401 , A61B2017/0408 , A61B2017/0409 , A61B2090/037 , A61F2/0805 , A61F2002/0835 , A61F2002/0864 , A61F2002/0888 , A61F2250/0071 , Y10S606/907
摘要： An expandable soft tissue fixation assembly for use in anchoring soft tissue to bone. The assembly includes a tab connected to an anchor, a sleeve adapted to surround the anchor, and a flange adapted to hold a soft tissue segment next to a bone. The sleeve is inserted into a blind hole in a bone, and a section of soft tissue is placed over the hole next to the bone. Energy is applied to the flange while a predetermined axial tension is applied to the tab to compress a flared portion of the anchor against the sleeve. An upper tube portion of the anchor and the flange are bonded together, and the applied axial force on the tab separates it from the anchor, leaving the assembly anchored in the bone and the soft tissue section anchored in place between the flange and the bone.
摘要翻译：一种用于将软组织固定到骨头的可扩展的软组织固定组件。组件包括连接到锚固件的突出部，适于围绕锚固件的套筒以及适于将软组织段保持在骨骼旁边的凸缘。将套筒插入骨中的盲孔中，将一部分软组织放置在靠近骨骼的孔上。能量被施加到凸缘上，同时将预定的轴向张力施加到凸片以将锚固件的扩口部分压靠套筒。锚固件和凸缘的上管部分结合在一起，并且在翼片上施加的轴向力将其与锚固件分开，使组件锚固在骨骼中，软组织部分锚固在凸缘和骨之间的适当位置。

8. 发明授权

US5417700A Automatic suturing and ligating device 失效
标题翻译：自动缝合和结扎装置
公开(公告)号：US5417700A
公开(公告)日：1995-05-23
申请号：US37021
申请日：1993-03-25
申请人： Thomas D. Egan
发明人： Thomas D. Egan
IPC分类号： A61B17/04 , A61B17/06 , A61B17/12 , A61B17/32
CPC分类号： A61B17/12013 , A61B17/0469 , A61B17/0467 , A61B17/0482 , A61B17/06066 , A61B17/320068 , A61B2017/0472 , A61B2017/06052 , A61B2017/06185 , A61B2017/0619
摘要： A device and method of suturing closed an opening and ligating a vessel or duct comprising removable tissue puncturing means (22) or vessel surrounding means establishing a continuous channel (24) through said tissue or around said vessel from each side. A completed channel (24) is formed and suture material (26) is threaded through the channel making a complete loop. The thread is secured at an anvil (30) independent from said puncturing/surrounding means. The puncturing/surrounding means is retracted leaving the thread, which is then tensioned closing the opening or occluding the vessel. The suture thread is secured and cut, forming a closed loop with overlapping ends. An energy transmitting device (38) melts the suture thread ends together forming a weld. The anvil (30) is removed leaving a knot-free completed stitch or ligature.
摘要翻译：缝合的装置和方法封闭开口并且连接容器或管道，其包括可移除的组织穿刺装置（22）或血管周围装置，其通过所述组织或从每一侧围绕所述血管建立连续通道（24）。形成完整的通道（24），缝合材料（26）穿过通道，形成完整的回路。螺纹固定在独立于穿刺/周围装置的砧座（30）上。穿刺/围绕装置缩回离开螺纹，然后将其张紧以封闭开口或闭塞容器。缝合线被固定和切割，形成具有重叠端部的闭合回路。能量传输装置（38）将缝合线端部熔化在一起形成焊缝。砧座（30）被移除，留下无结的针迹或结扎线。

9. 发明授权

US09125644B2 Apparatus and method for suturing tissue 有权
标题翻译：用于缝合组织的装置和方法
公开(公告)号：US09125644B2
公开(公告)日：2015-09-08
申请号：US13584536
申请日：2012-08-13
申请人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
发明人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
IPC分类号： A61B17/04 , A61B17/062 , A61B19/00
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0493 , A61B17/062 , A61B2017/0498 , A61B2090/0811
摘要： A suturing device of the present invention is in the form a compact, light-weight handheld device that includes a needle and suture assembly, a mechanism for gripping and releasing the needle/suture (a “needle transfer mechanism” or “needle shuttle mechanism”), safely capturing the needle/suture upon exit from the patient's tissue, and returning the needle to a position such that the process of delivering additional sutures to the patient can be repeated. A safety shield mechanism ensures the user is protected from the needle at all times. The device of the present invention accommodates the right or left-handed user, rests comfortably in the user's hand, allows sufficient visualization of the procedure site, and permits the user to either control penetration depth of the needle or default to a device-determined depth. The present device permits the user to utilize a wrist-rotation (pivoting) suture delivery technique.
摘要翻译：本发明的缝合装置形式为紧凑，重量轻的手持装置，其包括针和缝线组件，用于夹紧和释放针/缝合线的机构（“针传送机构”或“针穿机构” ），在从患者组织出来时安全地捕获针/缝合线，并且将针返回到一个位置，使得可以重复向患者输送附加缝合线的过程。安全屏蔽机构始终保证使用者免受针刺伤。本发明的装置容纳右手或左手的使用者舒适地放在使用者的手中，允许程序现场的足够可视化，并且允许用户控制针的穿透深度或默认为设备确定的深度。本装置允许使用者利用手腕旋转（枢转）缝线输送技术。

10. 发明申请

US20130041388A1 APPARATUS AND METHOD FOR SUTURING TISSUE 有权
标题翻译：装置和方法用于组织组织
公开(公告)号：US20130041388A1
公开(公告)日：2013-02-14
申请号：US13584536
申请日：2012-08-13
申请人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
发明人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
IPC分类号： A61B17/062
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0493 , A61B17/062 , A61B2017/0498 , A61B2090/0811
摘要： A suturing device of the present invention is in the form a compact, light-weight handheld device that includes a needle and suture assembly, a mechanism for gripping and releasing the needle/suture (a “needle transfer mechanism” or “needle shuttle mechanism”), safely capturing the needle/suture upon exit from the patient's tissue, and returning the needle to a position such that the process of delivering additional sutures to the patient can be repeated. A safety shield mechanism ensures the user is protected from the needle at all times. The device of the present invention accommodates the right or left-handed user, rests comfortably in the user's hand, allows sufficient visualization of the procedure site, and permits the user to either control penetration depth of the needle or default to a device-determined depth. The present device permits the user to utilize a wrist-rotation (pivoting) suture delivery technique.
摘要翻译：本发明的缝合装置形式为紧凑，重量轻的手持装置，其包括针和缝线组件，用于夹紧和释放针/缝线的机构（针传送机构或针穿机构），安全地捕获在从患者组织出来时针/缝合线，并且将针返回到这样的位置，使得可以重复向患者输送附加缝合线的过程。安全屏蔽机构始终保证使用者免受针刺伤。本发明的装置容纳右手或左手的使用者舒适地放在使用者的手中，允许程序现场的足够的可视化，并允许使用者控制针的穿透深度或默认为设备确定的深度。本装置允许使用者利用手腕旋转（枢转）缝线输送技术。

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