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1. 发明申请

US20150148731A1 METHODS AND DEVICES FOR INTRA-ATRIAL SHUNTS HAVING ADJUSTABLE SIZES 有权
标题翻译：具有可调节尺寸的内窥镜的方法和装置
公开(公告)号：US20150148731A1
公开(公告)日：2015-05-28
申请号：US14612022
申请日：2015-02-02
申请人： Edward I. MCNAMARA , Michael W. SUTHERLAND , Matthew J. FINCH , Stephen J. FORCUCCI , John MITZEL , David S. CELERMAJER , Hiroatsu SUGIMOTO
发明人： Edward I. MCNAMARA , Michael W. SUTHERLAND , Matthew J. FINCH , Stephen J. FORCUCCI , John MITZEL , David S. CELERMAJER , Hiroatsu SUGIMOTO
IPC分类号： A61M27/00
CPC分类号： A61B17/0057 , A61B2017/00247 , A61B2017/00575 , A61B2017/00584 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61F2/91 , A61F2/915 , A61F2002/075
摘要： Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter shunt portion which can be manually adjusted in vivo. Methods are provided for adjusting the flow rate of the devices in vivo.
摘要翻译：公开了通过使哺乳动物的心脏的左心房和右心房升高的血压正常化来治疗心脏病的装置和方法。设备可以包括可在体内手动调节的可调节的水力直径分流部分。提供了用于调节器件体内流速的方法。

2. 发明授权

US09125644B2 Apparatus and method for suturing tissue 有权
标题翻译：用于缝合组织的装置和方法
公开(公告)号：US09125644B2
公开(公告)日：2015-09-08
申请号：US13584536
申请日：2012-08-13
申请人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
发明人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
IPC分类号： A61B17/04 , A61B17/062 , A61B19/00
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0493 , A61B17/062 , A61B2017/0498 , A61B2090/0811
摘要： A suturing device of the present invention is in the form a compact, light-weight handheld device that includes a needle and suture assembly, a mechanism for gripping and releasing the needle/suture (a “needle transfer mechanism” or “needle shuttle mechanism”), safely capturing the needle/suture upon exit from the patient's tissue, and returning the needle to a position such that the process of delivering additional sutures to the patient can be repeated. A safety shield mechanism ensures the user is protected from the needle at all times. The device of the present invention accommodates the right or left-handed user, rests comfortably in the user's hand, allows sufficient visualization of the procedure site, and permits the user to either control penetration depth of the needle or default to a device-determined depth. The present device permits the user to utilize a wrist-rotation (pivoting) suture delivery technique.
摘要翻译：本发明的缝合装置形式为紧凑，重量轻的手持装置，其包括针和缝线组件，用于夹紧和释放针/缝合线的机构（“针传送机构”或“针穿机构” ），在从患者组织出来时安全地捕获针/缝合线，并且将针返回到一个位置，使得可以重复向患者输送附加缝合线的过程。安全屏蔽机构始终保证使用者免受针刺伤。本发明的装置容纳右手或左手的使用者舒适地放在使用者的手中，允许程序现场的足够可视化，并且允许用户控制针的穿透深度或默认为设备确定的深度。本装置允许使用者利用手腕旋转（枢转）缝线输送技术。

3. 发明申请

US20130041388A1 APPARATUS AND METHOD FOR SUTURING TISSUE 有权
标题翻译：装置和方法用于组织组织
公开(公告)号：US20130041388A1
公开(公告)日：2013-02-14
申请号：US13584536
申请日：2012-08-13
申请人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
发明人： Joseph P. Lane , Michael W. Sutherland , Thomas D. Egan , John DePiano
IPC分类号： A61B17/062
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0493 , A61B17/062 , A61B2017/0498 , A61B2090/0811
摘要： A suturing device of the present invention is in the form a compact, light-weight handheld device that includes a needle and suture assembly, a mechanism for gripping and releasing the needle/suture (a “needle transfer mechanism” or “needle shuttle mechanism”), safely capturing the needle/suture upon exit from the patient's tissue, and returning the needle to a position such that the process of delivering additional sutures to the patient can be repeated. A safety shield mechanism ensures the user is protected from the needle at all times. The device of the present invention accommodates the right or left-handed user, rests comfortably in the user's hand, allows sufficient visualization of the procedure site, and permits the user to either control penetration depth of the needle or default to a device-determined depth. The present device permits the user to utilize a wrist-rotation (pivoting) suture delivery technique.
摘要翻译：本发明的缝合装置形式为紧凑，重量轻的手持装置，其包括针和缝线组件，用于夹紧和释放针/缝线的机构（针传送机构或针穿机构），安全地捕获在从患者组织出来时针/缝合线，并且将针返回到这样的位置，使得可以重复向患者输送附加缝合线的过程。安全屏蔽机构始终保证使用者免受针刺伤。本发明的装置容纳右手或左手的使用者舒适地放在使用者的手中，允许程序现场的足够的可视化，并允许使用者控制针的穿透深度或默认为设备确定的深度。本装置允许使用者利用手腕旋转（枢转）缝线输送技术。

4. 发明申请

US20120259263A1 APPARATUS AND METHODS TO CREATE AND MAINTAIN AN INTRA-ATRIAL PRESSURE RELIEF OPENING 有权
标题翻译：装置和方法来创建和维持内部压力平衡开放
公开(公告)号：US20120259263A1
公开(公告)日：2012-10-11
申请号：US13370913
申请日：2012-02-10
申请人： David Celermajer , Edward McNamara , Michael W. Sutherland , Hiroatsu Sugimoto
发明人： David Celermajer , Edward McNamara , Michael W. Sutherland , Hiroatsu Sugimoto
IPC分类号： A61M1/00 , A61B18/00 , A61B17/34 , A61M25/10 , A61M29/02
CPC分类号： A61B17/0057 , A61B6/12 , A61B6/503 , A61B8/0841 , A61B8/0883 , A61B17/32 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B17/3478 , A61B18/1492 , A61B18/24 , A61B2017/00247 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/22044 , A61B2017/320004 , A61B2017/320008 , A61B2017/320064 , A61B2017/3488 , A61B2018/0022 , A61B2018/00351 , A61B2018/00577 , A61B2018/046 , A61B2018/1467 , A61M25/0068 , A61M25/0662 , A61M25/1002 , A61M29/02 , A61M2025/0039 , A61M2025/0681 , A61M2025/09008 , A61M2025/105 , A61M2025/1086 , A61M2025/1088 , A61N7/022
摘要： The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.
摘要翻译：本公开内容涉及通过使哺乳动物心脏的左心房和右心房升高的血压正常化来治疗心力衰竭的方法和装置。本公开包括用于在房间隔中产生和维持开口的方法。还公开了用于打开和扩大开口的工具。使用本文所述的技术和工具延长了心房内压力释放开口的通畅。

5. 发明申请

US20110190874A1 DEVICES AND METHODS FOR REDUCING VENOUS PRESSURE 有权
标题翻译：用于降低呼吸压力的装置和方法
公开(公告)号：US20110190874A1
公开(公告)日：2011-08-04
申请号：US13016290
申请日：2011-01-28
申请人： David Celermajer , Michael W. Sutherland , Edward McNamara
发明人： David Celermajer , Michael W. Sutherland , Edward McNamara
IPC分类号： A61F2/82
CPC分类号： A61F2/2475 , A61F2/2412 , A61F2/2418 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2250/0029 , A61F2250/0036
摘要： Devices and method are disclosed for reducing pressure in a patient's vena cava and in the right atrium of a patient's heart. A valve is implanted in the inferior vena cava (IFC) between the patient's renal veins and hepatic veins. When pressure in a patient's IFC reaches high levels, i.e., the pressure differential across the valve reaches high levels, the valve automatically closes or begins to close. The closing is caused by the pressure of the patient's blood moving one or more flaps in the valve to a closed or near-closed position. This prevents excessive pressure in the upper or superior vena cava and the right atrium of the patient's heart. The device also includes a pressure relief feature that opens and allows retrograde flow of blood if the pressure differential exceeds a yet higher pressure.
摘要翻译：公开了用于减轻患者的心脏腔内和右心房中的压力的装置和方法。瓣膜植入患者的肾静脉和肝静脉之间的下腔静脉（IFC）。当患者IFC中的压力达到高水平时，即跨过阀门的压差达到高水平时，阀门自动关闭或开始关闭。关闭是由于患者血液中的一个或多个瓣片移动到闭合或接近闭合位置的压力引起的。这可以防止患者心脏的上腔静脉和上腔静脉和右心房的压力过大。该装置还包括压力释放特征，如果压力差超过更高的压力，该压力释放特征将打开并允许血液逆行流动。

6. 发明申请

US20160022423A1 METHODS, SYSTEMS, AND DEVICES FOR RESIZABLE INTRA-ATRIAL SHUNTS 审中-公开
公开(公告)号：US20160022423A1
公开(公告)日：2016-01-28
申请号：US14878710
申请日：2015-10-08
申请人： Edward I. MCNAMARA , Michael W. SUTHERLAND , Matthew J. FINCH , Stephen J. FORCUCCI
发明人： Edward I. MCNAMARA , Michael W. SUTHERLAND , Matthew J. FINCH , Stephen J. FORCUCCI
IPC分类号： A61F2/24 , A61M27/00
CPC分类号： A61M27/002 , A61B2017/00247 , A61B2017/00575 , A61B2017/00584 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/2493
摘要： Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter and/or a removable and/or replaceable shunt portion. Devices may include absorbable materials, the absorption of which directly or indirectly causes alterations of the fluid flow capacities the devices.

7. 发明申请

US20120109155A1 HAND OPERATED DEVICE FOR CONTROLLED DEPLOYMENT OF A TISSUE ANCHOR AND METHOD OF USING THE SAME 有权
标题翻译：用于控制组装锚的部署的手动操作装置及其使用方法
公开(公告)号：US20120109155A1
公开(公告)日：2012-05-03
申请号：US13282139
申请日：2011-10-26
申请人： Jason H. Robinson , Steven Cahalane , Megan E. Holmes , Christopher C. Lee , Michael W. Sutherland , Aaron M. Call , James M. Sellers , Michael R. Cole , Gregory J. Kenny , Mathew S. Cardinali
发明人： Jason H. Robinson , Steven Cahalane , Megan E. Holmes , Christopher C. Lee , Michael W. Sutherland , Aaron M. Call , James M. Sellers , Michael R. Cole , Gregory J. Kenny , Mathew S. Cardinali
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/2833 , A61B18/1492 , A61B2017/00243 , A61B2017/003 , A61B2017/0046 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/048 , A61B2017/0496 , A61B2017/22038 , A61B2017/22074 , A61B2017/3447 , A61B2018/00357 , A61B2018/00601 , A61B2018/144 , A61B2090/3966 , A61M25/04
摘要： A tissue anchoring system includes a tissue anchor member that is suitable for anchoring against tissue. The system also includes a tensioning member operatively connected to the anchor member such that the anchor member can slide relative to the tensioning member, the tensioning member capable of being pulled to cause the anchor member to move relative to the tensioning member into a position seated against the tissue. A hand operated deployment catheter is operable to extend and deploy the anchor member therefrom. The deployment catheter includes a rotatable member about which the tensioning member is routed and a clutch assembly for limiting tension within the tensioning member to prevent the deployed anchor from being pulled through the tissue.
摘要翻译：组织锚固系统包括适于锚固组织的组织锚定构件。该系统还包括可操作地连接到锚定构件的张紧构件，使得锚定构件可相对于张紧构件滑动，张紧构件能够被拉动，使得锚定构件相对于张紧构件移动到与组织。手动部署导管可操作以从其延伸和展开锚固构件。展开导管包括可旋转构件，张紧构件围绕该旋转构件布置，以及用于限制张紧构件内的张力的离合器组件，以防止展开的锚被拉过组织。

8. 发明授权

US09277995B2 Devices and methods for reducing venous pressure 有权
标题翻译：降低静脉压的装置和方法
公开(公告)号：US09277995B2
公开(公告)日：2016-03-08
申请号：US13016290
申请日：2011-01-28
申请人： David Celermajer , Michael W. Sutherland , Edward McNamara
发明人： David Celermajer , Michael W. Sutherland , Edward McNamara
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2/2412 , A61F2/2418 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2250/0029 , A61F2250/0036
摘要： Devices and method are disclosed for reducing pressure in a patient's vena cava and in the right atrium of a patient's heart. A valve is implanted in the inferior vena cava (IFC) between the patient's renal veins and hepatic veins. When pressure in a patient's IFC reaches high levels, i.e., the pressure differential across the valve reaches high levels, the valve automatically closes or begins to close. The closing is caused by the pressure of the patient's blood moving one or more flaps in the valve to a closed or near-closed position. This prevents excessive pressure in the upper or superior vena cava and the right atrium of the patient's heart. The device also includes a pressure relief feature that opens and allows retrograde flow of blood if the pressure differential exceeds a yet higher pressure.
摘要翻译：公开了用于减轻患者的心脏腔内和右心房中的压力的装置和方法。瓣膜植入患者的肾静脉和肝静脉之间的下腔静脉（IFC）。当患者IFC中的压力达到高水平时，即跨过阀门的压差达到高水平时，阀门自动关闭或开始关闭。关闭是由于患者血液中的一个或多个瓣片移动到闭合或接近闭合位置的压力引起的。这可以防止患者心脏的上腔静脉和上腔静脉和右心房的压力过大。该装置还包括压力释放特征，如果压力差超过更高的压力，该压力释放特征将打开并允许血液逆行流动。

9. 发明授权

US08968335B2 Hand operated device for controlled deployment of a tissue anchor and method of using the same 有权
标题翻译：用于组织锚的受控部署的手动装置及其使用方法
公开(公告)号：US08968335B2
公开(公告)日：2015-03-03
申请号：US13282139
申请日：2011-10-26
申请人： Jason H. Robinson , Steven Cahalane , Megan E. Holmes , Christopher C. Lee , Michael W. Sutherland , Aaron M. Call , James M. Sellers , Michael R. Cole , Gregory J. Kenny , Mathew S. Cardinali
发明人： Jason H. Robinson , Steven Cahalane , Megan E. Holmes , Christopher C. Lee , Michael W. Sutherland , Aaron M. Call , James M. Sellers , Michael R. Cole , Gregory J. Kenny , Mathew S. Cardinali
IPC分类号： A61B17/10 , A61B17/04 , A61B17/28 , A61B18/14 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/00 , A61B19/00 , A61M25/04
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/2833 , A61B18/1492 , A61B2017/00243 , A61B2017/003 , A61B2017/0046 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/048 , A61B2017/0496 , A61B2017/22038 , A61B2017/22074 , A61B2017/3447 , A61B2018/00357 , A61B2018/00601 , A61B2018/144 , A61B2090/3966 , A61M25/04
摘要： A tissue anchoring system includes a tissue anchor member that is suitable for anchoring against tissue. The system also includes a tensioning member operatively connected to the anchor member such that the anchor member can slide relative to the tensioning member, the tensioning member capable of being pulled to cause the anchor member to move relative to the tensioning member into a position seated against the tissue. A hand operated deployment catheter is operable to extend and deploy the anchor member therefrom. The deployment catheter includes a rotatable member about which the tensioning member is routed and a clutch assembly for limiting tension within the tensioning member to prevent the deployed anchor from being pulled through the tissue.
摘要翻译：组织锚固系统包括适于锚固组织的组织锚固构件。该系统还包括可操作地连接到锚定构件的张紧构件，使得锚定构件可相对于张紧构件滑动，张紧构件能够被拉动，使得锚定构件相对于张紧构件移动到与组织。手动部署导管可操作以从其延伸和展开锚固构件。展开导管包括可旋转构件，张紧构件围绕该旋转构件布置，以及用于限制张紧构件内的张力的离合器组件，以防止展开的锚被拉过组织。

10. 发明授权

US08882697B2 Apparatus and methods to create and maintain an intra-atrial pressure relief opening 有权
标题翻译：用于创建和维持心房内压力释放开口的装置和方法
公开(公告)号：US08882697B2
公开(公告)日：2014-11-11
申请号：US13370913
申请日：2012-02-10
申请人： David Celermajer , Edward McNamara , Michael W. Sutherland , Hiroatsu Sugimoto
发明人： David Celermajer , Edward McNamara , Michael W. Sutherland , Hiroatsu Sugimoto
IPC分类号： A61M1/00 , A61B18/00 , A61B17/34 , A61M25/00 , A61M29/02 , A61B17/32 , A61B17/3205 , A61B8/08 , A61B6/00 , A61N7/02 , A61B6/12 , A61B17/00 , A61B18/14 , A61B17/22
CPC分类号： A61B17/0057 , A61B6/12 , A61B6/503 , A61B8/0841 , A61B8/0883 , A61B17/32 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B17/3478 , A61B18/1492 , A61B18/24 , A61B2017/00247 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/22044 , A61B2017/320004 , A61B2017/320008 , A61B2017/320064 , A61B2017/3488 , A61B2018/0022 , A61B2018/00351 , A61B2018/00577 , A61B2018/046 , A61B2018/1467 , A61M25/0068 , A61M25/0662 , A61M25/1002 , A61M29/02 , A61M2025/0039 , A61M2025/0681 , A61M2025/09008 , A61M2025/105 , A61M2025/1086 , A61M2025/1088 , A61N7/022
摘要： The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.
摘要翻译：本公开内容涉及通过使哺乳动物心脏的左心房和右心房升高的血压正常化来治疗心力衰竭的方法和装置。本公开包括用于在房间隔中产生和维持开口的方法。还公开了用于打开和扩大开口的工具。使用本文所述的技术和工具延长了心房内压力释放开口的通畅。

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