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1. 发明申请

WO2016100624A1 COMPOSITIONS AND METHODS FOR IMPROVING ABIOTIC STRESS TOLERANCE 审中-公开
标题翻译：用于改善生物耐压性的组合物和方法
公开(公告)号：WO2016100624A1
公开(公告)日：2016-06-23
申请号：PCT/US2015/066298
申请日：2015-12-17
申请人： SYNGENTA PARTICIPATIONS AG , SYNGENTA CROP PROTECTION, LLC
发明人： BASU, Shib Sankar
IPC分类号： C12N5/14 , C07K14/415
CPC分类号： C12N15/8261 , A01H1/02 , C07K14/415 , C12N15/8201 , C12N15/8271 , C12N15/8273 , C12Q1/6895 , Y02A40/146
摘要： The present invention relates to compositions and methods for improving yield, yield stability, and/or drought stress tolerance in plants. Plants and/or plant parts identified, selected and/or produced using compositions and methods of the present invention are also provided.
摘要翻译：本发明涉及用于在植物中提高产量，产量稳定性和/或干旱胁迫耐受性的组合物和方法。还提供了使用本发明的组合物和方法鉴定，选择和/或生产的植物和/或植物部分。

2. 发明申请

WO2009110933A8 ENGINEERING ENZYMATICALLY SUSCEPTIBLE PHYTASES 审中-公开
公开(公告)号：WO2009110933A8
公开(公告)日：2009-09-11
申请号：PCT/US2008/084294
申请日：2008-11-21
申请人： SYNGENTA PARTICIPATIONS AG , BASU, Shib Sankar , ZHANG, Shengsheng
发明人： BASU, Shib Sankar , ZHANG, Shengsheng
IPC分类号： A01H5/00
摘要： The invention provides a synthetic phytase polypeptide which encodes an en/ymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.

3. 发明申请

WO2009073399A2 ENGINEERING ENZYMATICALLY SUSCEPTIBLE PROTEINS 审中-公开
标题翻译：工程酶催化蛋白质
公开(公告)号：WO2009073399A2
公开(公告)日：2009-06-11
申请号：PCT/US2008/084303
申请日：2008-11-21
申请人： SYNGENTA PARTICIPATIONS AG , BASU, Shib Sankar , ZHANG, Shengsheng
发明人： BASU, Shib Sankar , ZHANG, Shengsheng
IPC分类号： C07K14/43
CPC分类号： A23K20/189 , A23K50/75 , C12N9/16
摘要： The invention provides a synthetic phytase polypeptide which encodes an enzymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.
摘要翻译：本发明提供了编码酶敏感肌醇六磷酸酶的合成肌醇六磷酸酶多肽。还提供了包含酶易感性肌醇六磷酸酶的饲料或食品，以及表达酶敏感肌醇六磷酸酶的转基因植物。进一步提供了制备和使用酶敏感肌醇六磷酸酶的方法，例如在饲料和食品加工中使用酶敏感肌醇六磷酸酶的方法。

4. 发明申请

WO2012047794A1 METHODS OF DETERMINING PLANT ZYGOSITY USING MASS SPECTROMETRY 审中-公开
标题翻译：使用质谱分析方法确定植物的ZYGOSITY
公开(公告)号：WO2012047794A1
公开(公告)日：2012-04-12
申请号：PCT/US2011/054579
申请日：2011-10-03
申请人： SYNGENTA PARTICIPATIONS AG , BASU, Shib Sankar
发明人： BASU, Shib Sankar
IPC分类号： G01N33/50 , G01N30/72
CPC分类号： G01N33/6848 , A01H1/04 , G01N30/7233 , G01N2333/415
摘要： The present invention relates to methods and systems for identifying seeds that are homozygous for an allele of interest and/or for identifying seeds that are likely to produce plants possessing a desired trait. Methods of producing plants that are homozygous for an allele of interest and/or that possess a desired trait are also provided.
摘要翻译：本发明涉及用于鉴定对于感兴趣的等位基因是纯合的种子和/或鉴定可能产生具有所需性状的植物的种子的方法和系统。还提供了产生对目的等位基因是纯合的植物和/或具有所需性状的植物的方法。

5. 发明申请

WO2011156539A3 COMPOSITIONS AND METHODS FOR PROTEIN PRODUCTION 审中-公开
公开(公告)号：WO2011156539A3
公开(公告)日：2011-12-15
申请号：PCT/US2011/039701
申请日：2011-06-09
申请人： SYNGENTA PARTICIPATIONS AG , BASU, Shib Sankar , DANG, Kristen Kamerath , AZHAKANANDAM, Kasimalai , MCNEILL, Thomas Z. , GUO, Sheng
发明人： BASU, Shib Sankar , DANG, Kristen Kamerath , AZHAKANANDAM, Kasimalai , MCNEILL, Thomas Z. , GUO, Sheng
IPC分类号： C07H21/02 , C07H21/04
摘要： The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.

6. 发明公开

EP2625521A1 METHODS OF DETERMINING PLANT ZYGOSITY USING MASS SPECTROMETRY 审中-公开
标题翻译：方法用于确定植物的半合子BY MASS
公开(公告)号：EP2625521A1
公开(公告)日：2013-08-14
申请号：EP11831390.7
申请日：2011-10-03
申请人： Syngenta Participations AG
发明人： BASU, Shib Sankar
IPC分类号： G01N33/50 , G01N30/72
CPC分类号： G01N33/6848 , A01H1/04 , G01N30/7233 , G01N2333/415
摘要： The present invention relates to methods and systems for identifying seeds that are homozygous for an allele of interest and/or for identifying seeds that are likely to produce plants possessing a desired trait. Methods of producing plants that are homozygous for an allele of interest and/or that possess a desired trait are also provided.

7. 发明授权

EP2580230B1 COMPOSITIONS AND METHODS FOR PROTEIN PRODUCTION 有权
标题翻译：蛋白质生产的组合物和方法
公开(公告)号：EP2580230B1
公开(公告)日：2017-08-23
申请号：EP11793130.3
申请日：2011-06-09
申请人： Syngenta Participations AG
发明人： BASU, Shib Sankar , DANG, Kristen Kamerath , AZHAKANANDAM, Kasimalai , MCNEILL, Thomas Z. , GUO, Sheng
IPC分类号： C07H21/02 , C07H21/04
CPC分类号： C12N15/1089 , C12N15/1034
摘要： The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.
摘要翻译：本发明提供了选择用于产生感兴趣多肽的mRNA的方法，包括：a）产生包含编码感兴趣多肽的不同核苷酸序列的单个mRNA序列阵列; b）对于（a）的每个单独的mRNA序列确定一个或多个或两个或更多个以下参数：（i）最小自由能（MFE）RNA二级结构; （ii）集合自由能（EFE）; （iii）热力学系综中最小自由能（FMFE）RNA二级结构的频率; 和（四）集合多样性（ED）; c）根据步骤（b）中确定的参数对阵列的单个mRNA序列进行排序; 和d）从步骤（c）的分级阵列中选择mRNA序列，其中所选mRNA产生目的多肽。本发明进一步提供了选择用于增强和减少感兴趣多肽生产的mRNA的方法。

8. 发明公开

EP2580230A2 COMPOSITIONS AND METHODS FOR PROTEIN PRODUCTION 有权
标题翻译：组合物和蛋白质制备方法
公开(公告)号：EP2580230A2
公开(公告)日：2013-04-17
申请号：EP11793130.3
申请日：2011-06-09
申请人： Syngenta Participations AG
发明人： BASU, Shib Sankar , DANG, Kristen Kamerath , AZHAKANANDAM, Kasimalai , MCNEILL, Thomas Z. , GUO, Sheng
IPC分类号： C07H21/02 , C07H21/04
CPC分类号： C12N15/1089 , C12N15/1034
摘要： The present invention provides a method of selecting a mRNA for production of a polypeptide of interest comprising: a) producing an array of individual mRNA sequences comprising different nucleotide sequences encoding the polypeptide of interest; b) determining one or more or two or more of the following parameters for each individual mRNA sequence of (a): (i) minimum free energy (MFE) RNA secondary structure; (ii) ensemble free energy (EFE); (iii) frequency of the minimum free energy (FMFE) RNA secondary structure in a thermodynamic ensemble; and (iv) ensemble diversity (ED); c) ranking the individual mRNA sequences of the array according the parameters determined in step (b); and d) selecting a mRNA sequence from the ranked array of step (c), wherein the selected mRNA produces the polypeptide of interest. The present invention further provides a method of selecting a mRNA for enhanced and reduced production of a polypeptide of interest.

9. 发明授权

EP2219469B1 ENGINEERING ENZYMATICALLY SUSCEPTIBLE PROTEINS 有权
标题翻译：工程酶催化蛋白质
公开(公告)号：EP2219469B1
公开(公告)日：2017-08-30
申请号：EP08858249.9
申请日：2008-11-21
申请人： Syngenta Participations AG
发明人： BASU, Shib Sankar , ZHANG, Shengsheng
IPC分类号： C12N15/82
CPC分类号： A23K20/189 , A23K50/75 , C12N9/16

10. 发明公开

EP2219469A2 ENGINEERING ENZYMATICALLY SUSCEPTIBLE PROTEINS 有权
标题翻译：工程师VENFÜRENZYMEZUGÄNGLICHENPROTEINEN
公开(公告)号：EP2219469A2
公开(公告)日：2010-08-25
申请号：EP08858249.9
申请日：2008-11-21
申请人： Syngenta Participations AG
发明人： BASU, Shib Sankar , ZHANG, Shengsheng
IPC分类号： A23K1/165 , C12N15/82
CPC分类号： A23K20/189 , A23K50/75 , C12N9/16
摘要： The invention provides a synthetic phytase polypeptide which encodes an enzymatically susceptible phytase. Also provided are feed or food products comprising an enzymatically susceptible phytase, and transgenic plants which express the enzymatically susceptible phytase. Further provided are methods for making and using enzymatically susceptible phytases, e.g., a method of using an enzymatically susceptible phytase in feed and food processing.
摘要翻译：本发明提供编码酶易感的植酸酶的合成植酸酶多肽。还提供了包含酶敏感的植酸酶的饲料或食品，以及表达酶敏感性植酸酶的转基因植物。还提供了制备和使用酶敏感的植酸酶的方法，例如在饲料和食品加工中使用酶促易感的植酸酶的方法。

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