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1. 发明申请

WO2004024930A2 PROCESS FOR PRODUCTION OF TRANSESTERIFIED OILS/FATS OR TRIGLYCERIDES 审中-公开
标题翻译：生产酯交换油/脂肪或甘油三酯的方法
公开(公告)号：WO2004024930A2
公开(公告)日：2004-03-25
申请号：PCT/JP2003/011744
申请日：2003-09-12
申请人： SUNTORY LIMITED , SUMIDA, Motoo , HIGASHIYAMA, Kenichi
发明人： SUMIDA, Motoo , HIGASHIYAMA, Kenichi
IPC分类号： C12P7/00
CPC分类号： C12P7/6472 , A23D9/00 , A23K20/158 , A23L33/115 , A23V2002/00 , C11C3/10 , A23V2250/1862
摘要： There are provided polyunsaturated fatty acids-containing oils/fats or triglycerides with high digestion and absorption properties and resistance to oxidative damage, which are suitable for applications in fields such as modified milk for infants, food products and healthy foods and/or supplements, produced by transesterification of polyunsaturated fatty acids-containing oils/fats or triglycerides with vegetable oils/fats or triglycerides using 1,3-position specific type lipases.
摘要翻译：提供了具有高消化吸收性能和抗氧化损伤性能的含有多不饱和脂肪酸的油/脂肪或甘油三酯，其适用于诸如婴儿用改性乳，食品和食品等领域的应用。通过使用1,3位特异性脂肪酶通过含多不饱和脂肪酸的油/脂肪或甘油三酯与植物油/脂肪或甘油三酯进行酯交换而产生的健康食品和/或补充剂。

2. 发明申请

WO2004033698A2 PROCESS FOR PRODUCING MICROBIAL FAT OR OIL HAVING LOWERED UNSAPONIFIABLE MATTER CONTENT AND SAID FAT OR OIL 审中-公开
标题翻译：生产微生物脂肪或油的方法，具有降低的不可解释的物质含量和油脂
公开(公告)号：WO2004033698A2
公开(公告)日：2004-04-22
申请号：PCT/JP2003/013000
申请日：2003-10-09
申请人： SUNTORY LIMITED , AKIMOTO, Kengo , HIGASHIYAMA, Kenichi , KAWASHIMA, Hiroshi , SUMIDA, Motoo
发明人： AKIMOTO, Kengo , HIGASHIYAMA, Kenichi , KAWASHIMA, Hiroshi , SUMIDA, Motoo
IPC分类号： C12P7/00
CPC分类号： C12P7/6472 , A23D9/02
摘要： A process for producing a crude oil having lowered unsaponifiable matter content and/or ester-type sterol content and comprising a highly unsaturated fatty acid as a constituent fatty acid, characterized in that a microorganism capable of producing a fat or oil comprising an unsaturated fatty acid as a constituent fatty acid is cultured in a medium containing a nitrogen source concentration of 2 to 15% within a culture tank equipped with an agitation impeller satisfying the requirement that the ratio of the diameter of agitation impeller (= d) to the inner diameter of the culture tank (= D) is d/D = 0.30 to 0.6.
摘要翻译：一种生产具有降低的不皂化物质含量和/或酯类固醇含量并含有高度不饱和脂肪酸作为构成脂肪酸的原油的方法，其特征在于，能够生产包含不饱和脂肪酸的脂肪或油的微生物作为构成脂肪酸，在含有浓度为2〜15％的氮源的培养基中培养，在配备有搅拌叶轮的培养槽中，搅拌叶轮满足搅拌叶轮直径（= d）与内径培养罐（= D）为d / D = 0.30〜0.6。

3. 发明申请

WO2006085672A2 PRODUCTION OF POLYUNSATURATED FATTY ACIDS USING NOVEL CELL TREATMENT METHOD 审中-公开
标题翻译：使用新型细胞处理方法生产聚氨酯脂肪酸
公开(公告)号：WO2006085672A2
公开(公告)日：2006-08-17
申请号：PCT/JP2006/302589
申请日：2006-02-08
申请人： SUNTORY LIMITED , HIGASHIYAMA, Kenichi , NAKAJIMA, Toshiharu
发明人： HIGASHIYAMA, Kenichi , NAKAJIMA, Toshiharu
IPC分类号： C12P1/00 , C12P1/02 , C12P7/64 , C12P9/00 , C12N1/14 , C12N1/12 , C12N1/04 , A23D7/00 , A61K31/00 , A23L1/00 , A23K1/00
CPC分类号： A23D9/00 , A23K10/12 , A23K20/158 , A23L33/115 , A23V2002/00 , C11B1/10 , C12N1/005 , C12P7/6472 , C12P7/6481 , A23V2250/1882
摘要： ABSTRACT A method for isolating one compound or more than one compounds from a biomass which contains microorganisms that have produced the compound or compounds, the method comprising the following steps: (a) preparing or obtaining wet cells having an average moisture content of between 30% and 80%; (b) subjecting the wet cells to primary drying to obtain primary dried cells having an average moisture content of between 5% and 50%; (c) subjecting the primary dried cells obtained in (b) to secondary drying to obtain secondary dried cells having an average moisture content of no greater than 10%; and (d) extracting or isolating, purifying and/or refining the compound or each of the compounds from the secondary dried cells obtained in (c).
摘要翻译：摘要一种从含有生成化合物或微生物的微生物的生物质中分离一种化合物或一种以上化合物的方法，该方法包括以下步骤：（a）制备或获得平均含水量为30％和80％; （b）使湿细胞进行一次干燥，得到平均含水量在5％至50％之间的初级干燥细胞; （c）使（b）中获得的一次干燥的细胞二次干燥，得到平均含水量不大于10％的二次干燥细胞; 和（d）从（c）中获得的二次干燥细胞提取或分离，纯化和/或精制化合物或每种化合物。

4. 发明申请

WO2006016702A1 METHOD FOR POLYUNSATURATED FATTY ACID PRODUCTION USING NOVEL CELL PRESERVATION TECHNIQUE 审中-公开
标题翻译：使用新型细胞保存技术聚合脂肪酸生产的方法
公开(公告)号：WO2006016702A1
公开(公告)日：2006-02-16
申请号：PCT/JP2005/014960
申请日：2005-08-10
申请人： SUNTORY LIMITED , HIGASHIYAMA, Kenichi
发明人： HIGASHIYAMA, Kenichi
IPC分类号： C12N1/04
CPC分类号： C12P7/6427 , C12N1/04 , C12N1/14 , C12P7/6472 , C12P7/6481
摘要： A method for preservation of a microorganism capable of microbial production of a polyunsaturated fatty acid or a compound comprising a polyunsaturated fatty acid as a constituent fatty acid, which method comprises: (a) forming spores in a spore-forming medium at pH 4-7 containing a nutrient source comprising an inorganic salt and a saccharide; (b) suspending the spores obtained in (a) in sterilized water, or sterilized water containing a surfactant and/or an inorganic salt to prepare a spore suspension, and adding a cryoprotectant at 5-15% to prepare a cryopreserving spore suspension; and (c) preserving the cryopreserving spore suspension obtained in (b) at between -100°C and -20°C.
摘要翻译：一种保存能够微生物生产多不饱和脂肪酸的微生物或包含多不饱和脂肪酸作为构成脂肪酸的化合物的方法，该方法包括：（a）在pH 4-7的孢子形成培养基中形成孢子含有包含无机盐和糖的营养源; （b）将（a）中获得的孢子悬浮于无菌水中，或将含有表面活性剂和/或无机盐的无菌水悬浮以制备孢子悬浮液，并加入5-15％的冷冻保护剂以制备冷冻保存孢子悬浮液; 和（c）在-100℃和-20℃之间保存（b）中获得的冷冻保存孢子悬浮液。

5. 发明公开

EP0960943A1 MEDIA FOR CULTURING MICROORGANISMS AND PROCESS FOR PRODUCING UNSATURATED FATTY ACIDS OR LIPIDS CONTAINING THE SAME 无效
标题翻译：培养基用于生产不饱和脂肪酸或含脂类微生物和方法
公开(公告)号：EP0960943A1
公开(公告)日：1999-12-01
申请号：EP97950433.9
申请日：1997-12-26
申请人： SUNTORY LIMITED
发明人： HIGASHIYAMA, Kenichi , YAGUCHI, Toshiaki , AKIMOTO, Kengo , SHIMIZU, Sakayu
IPC分类号： C12P7/64 , C12N1/14
CPC分类号： C12P7/6427 , C12N1/14 , C12P7/6472
摘要： A process for controlling the mycelial morphology of a microorganism belonging to the genus Mortierella during culturing and a process for producing unsaturated fatty acids and a lipid containing them by using a culture medium for culturing a microorganism in which phosphate ions, potassium ions, sodium ions, magnesium ions, and calcium ions in the culture medium are in the range of 5 to 60 mM, 5 to 60 mM, 2 to 50 mM, 0.5 to 9 mM, and 0.5 to 12 mM, respectively, characterized in that the microorganism belonging to the genus Mortierella is cultured in a culture medium containing phosphate ions in the range of 5 to 60 mM, potassium ions in the range of 5 to 60 mM, sodium ions in the range of 2 to 50 mM, magnesium ions in the range of 0.5 to 9 mM, and calcium ions in the range of 0.5 to 12 mM, respectively, to produce unsaturated fatty acids and the lipid containing them, and the culture medium for culturing a microorganism having phosphate ions, potassium ions, sodium ions, magnesium ions, and calcium ions in the range of 5 to 60 mM, 5 to 60 mM, 2 to 50 mM, 0.5 to 9 mM, and 0.5 to 12 mM, respectively.
摘要翻译：一种用于控制属于被孢霉属的微生物的培养过程中的菌丝体的形态和用于生产不饱和脂肪酸的方法和过程的脂质含通过使用用于培养在其中磷酸根离子，钾离子，钠离子的微生物的培养基中培养它们，镁离子，和在培养基中的钙离子是在5至60毫米，5到60毫米，2至50mM，0.5至9毫米的范围内，和0.5至12mm，分别在DASS模具微生物属于特点被孢霉属是在培养基中含有磷酸根离子的范围内培养5至60毫米，钾离子的范围为5至60毫米，钠离子在2至50mM的镁离子在0.5的范围内的范围内至9mm，和在0.5至12mm的范围内的钙离子，分别以产生不饱和脂肪酸和脂质含有它们，以及用于培养微生物具有磷酸根离子，钾离子，钠离子，镁离子的培养基 S，和钙离子在5至60毫米，5到60毫米，2〜分别为50mm，0.5至9毫米，和0.5至12毫米，的范围内。

6. 发明授权

EP0775449B8 FOWL EGGS WITH HIGH CONTENT OF HIGHLY UNSATURATED FATTY ACIDS, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF 失效
标题翻译：随着对多个生产不饱和脂肪酸比例很高，方法及其使用鸡蛋
公开(公告)号：EP0775449B8
公开(公告)日：2005-11-09
申请号：EP96919998.3
申请日：1996-05-29
申请人： SUNTORY LIMITED , Bizen Chemical Co., Ltd.
发明人： HIGASHIYAMA, Kenichi , ISHIHARA, Takafumi, Bizen Chemical Co., Ltd. , KANADA, Teruyuki, Bizen Chemical Co., Ltd. , TANAKA, Yoshiharu , ARAI, Motoharu ,
IPC分类号： A23K1/18 , A23K1/16 , A23L1/30 , C07C57/00
CPC分类号： C12P7/6472 , A23D9/00 , A23J1/08 , A23K20/158 , A23K50/75 , A23L15/20 , A23L33/12 , A23V2002/00 , C07C53/126 , C07C57/12 , C12P7/6427 , A23V2250/1868 , A23V2250/187 , A23V2250/1862
摘要： Fowl eggs with a high arachidonic acid content and optionally further with a high docosahexaenoic acid content produced by feeding fowl for ovum-recovery use with φ-6 highly unsaturated fatty acids and optionally further with φ-3 highly unsaturated fatty acids; a process for producing the eggs; fats or oils derived therefrom; and foods containing the fats or oils.

7. 发明授权

EP0775449B1 FOWL EGGS WITH HIGH CONTENT OF HIGHLY UNSATURATED FATTY ACIDS, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF 失效
标题翻译：具有高度不饱和脂肪酸含量的FOWL鸡蛋，其生产方法及其用途
公开(公告)号：EP0775449B1
公开(公告)日：2005-09-07
申请号：EP96919998.3
申请日：1996-05-29
申请人： SUNTORY LIMITED , Bizen Chemical Co., Ltd.
发明人： AKIMOTO, Kengo , HIGASHIYAMA, Kenichi , ISHIHARA, Takafumi, Bizen Chemical Co., Ltd. , KANADA, Teruyuki, Bizen Chemical Co., Ltd. , TANAKA, Yoshiharu , ARAI, Motoharu
IPC分类号： A23K1/18 , A23K1/16 , A23L1/30 , C07C57/00
CPC分类号： C12P7/6472 , A23D9/00 , A23J1/08 , A23K20/158 , A23K50/75 , A23L15/20 , A23L33/12 , A23V2002/00 , C07C53/126 , C07C57/12 , C12P7/6427 , A23V2250/1868 , A23V2250/187 , A23V2250/1862
摘要： Fowl eggs with a high arachidonic acid content and optionally further with a high docosahexaenoic acid content produced by feeding fowl for ovum-recovery use with φ-6 highly unsaturated fatty acids and optionally further with φ-3 highly unsaturated fatty acids; a process for producing the eggs; fats or oils derived therefrom; and foods containing the fats or oils.
摘要翻译：具有高花生四烯酸含量的禽蛋，并且任选地进一步具有通过喂养家禽用于使用φ-6高度不饱和脂肪酸以及任选地进一步与φ-3高度不饱和脂肪酸一起用于卵子回收的高二十二碳六烯酸含量; 一种生产鸡蛋的方法; 由其衍生的脂肪或油; 和含有脂肪或油的食物。

8. 发明公开

EP0957173A1 PROCESS FOR PREPARING FAT OR OIL CONTAINING UNSATURATED FATTY ACID 失效
标题翻译：用于生产不饱和脂肪酸的含酸性脂肪或油
公开(公告)号：EP0957173A1
公开(公告)日：1999-11-17
申请号：EP97937813.0
申请日：1997-08-27
申请人： SUNTORY LIMITED
发明人： HIGASHIYAMA, Kenichi , AKIMOTO, Kengo , SHIMIZU, Sakayu
IPC分类号： C12P7/64
CPC分类号： C12P7/6472 , A23D9/00 , A23K20/158 , A23L33/12 , A23L33/40 , A23V2002/00 , C12P7/64 , Y10S426/801 , Y10S426/807 , A23V2250/54252 , A23V2250/1874 , A23V2250/1868 , A23V2250/1862 , A23V2250/187 , A23V2250/612 , A23V2250/28 , A23V2250/70 , A23V2250/156
摘要： A process for production of unsaturated fatty acid-containing oils which is characterized by culturing a microorganism belonging to the genus Mortierella subgenus Mortierella in a medium containing a nitrogen source derived from soybean, and collecting the unsaturated fatty acid-containing oil from the cultured product. The oils are obtained with a low 24,25-methylenecholest-5-en-3β-ol content.

9. 发明公开

EP1894472A1 Edible oil containing arachidonic acid and foods containing the same 失效
标题翻译： SpeiseölmitArachidonsäureund damit versehene Nahrungsmittel
公开(公告)号：EP1894472A1
公开(公告)日：2008-03-05
申请号：EP07118999.7
申请日：1997-10-09
申请人： SUNTORY LIMITED , NIPPON SUISAN KAISHA, LTD.
发明人： HIGASHIYAMA, Kenichi , AKIMOTO, Kengo , SHIMIZU, Sakayu , DOISAKI, Nobushige c/o NIPPON SUISAN KAISHA LTD. , FURIHATA, Kiyomi c/o NIPPON SUISAN KAISHA LTD.
IPC分类号： A23D9/007
CPC分类号： A23D9/00 , A23L33/12 , A23L33/40 , A23V2002/00 , A23V2250/1862
摘要： Edible oil containing arachidonic acid obtained from microorganisms belonging to the subgenus Mortierella of the genus Mortierella and being capable of producing arachidonic acid are provided. The oil contain little unsaponifiable matters and, above all, the smallest possible amount of sterol with cyclopropane structure which have not been recognized as food components, and are suitable for the production of foods, in particular, infant formula.
Arachidonic acid-containing edible oil originating in microorganisms containing not more than 0.8% by weight, preferably not more than 0.6% by weight of unsaponifiable matters and 20% by weight or more of arachidonic acid. Further, these edible oil contain not more than 0.3% by weight, preferably not more than 0.15% by weight of 24,25-methylenecholest-5-en-3β-ol. The microorganisms are those belonging to the subgenus Mortierella of the genus Mortierella and being capable of producing arachidonic acid. These microorganisms belong to the species alpina of the genus Mortierella. Foods including the arachidonic acid-containing edible oil. Formula for premature infants, formula for infants, foods for infants, and foods for pregnant women and nursing mothers, including the arachidonic acid-containing edible oil.
摘要翻译：提供了含有花生四烯酸的食用油，其由属于被孢霉属的被孢霉属亚属的微生物获得，并且能够产生花生四烯酸。该油含有少量不皂化物质，最重要的是尽可能少量的具有环丙烷结构的固醇未被认定为食品成分，适用于生产食品，特别是婴儿配方奶粉。含有不超过0.8重量％，优选不超过0.6重量％的不皂化物和20重量％以上花生四烯酸的微生物的含花生四烯酸的食用油。此外，这些食用油含有不多于0.3重量％，优选不超过0.15重量％的24,25-亚甲基胆甾-5-烯-3-醇。这些微生物是属于被孢霉属的被孢霉属亚属的能够产生花生四烯酸的微生物。这些微生物属于被孢霉属的alpina属。食物包括含花生四烯酸的食用油。早产儿配方奶粉，婴儿配方奶粉，婴儿食品，孕妇和哺乳母亲食品，包括含花生四烯酸的食用油。

10. 发明公开

EP1776450A1 METHOD FOR POLYUNSATURATED FATTY ACID PRODUCTION USING NOVEL CELL PRESERVATION TECHNIQUE 有权转让
标题翻译：用于生产多不饱和脂肪酸对于新的细胞水土保持科技
公开(公告)号：EP1776450A1
公开(公告)日：2007-04-25
申请号：EP05772543.4
申请日：2005-08-10
申请人： SUNTORY LIMITED
发明人： HIGASHIYAMA, Kenichi
IPC分类号： C12N1/04 , C12N1/14 , C12P7/64
CPC分类号： C12P7/6427 , C12N1/04 , C12N1/14 , C12P7/6472 , C12P7/6481
摘要： A method for preservation of a microorganism capable of microbial production of a polyunsaturated fatty acid or a compound comprising a polyunsaturated fatty acid as a constituent fatty acid, which method comprises: (a) forming spores in a spore-forming medium at pH 4-7 containing a nutrient source comprising an inorganic salt and a saccharide; (b) suspending the spores obtained in (a) in sterilized water, or sterilized water containing a surfactant and/or an inorganic salt to prepare a spore suspension, and adding a cryoprotectant at 5-15% to prepare a cryopreserving spore suspension; and (c) preserving the cryopreserving spore suspension obtained in (b) at between -100°C and -20°C.

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