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1. 发明申请

WO2009005542A3 DETECTION OF BIOAGENTS USING A SHEAR HORIZONTAL SURFACE ACOUSTIC WAVE BIOSENSOR 审中-公开
标题翻译：使用剪切水平表面声波生物传感器检测生物剂
公开(公告)号：WO2009005542A3
公开(公告)日：2009-04-16
申请号：PCT/US2008001721
申请日：2008-02-08
申请人： STC UNM , SANDIA CORP , LARSON RICHARD S , HJELLE BRIAN , HALL PAM R , BROWN DAVID C , BISOFFI MARCO , BROZIK SUSAN M , BRANCH DARREN W , EDWARDS THAYNE L , WHEELER DAVID
发明人： LARSON RICHARD S , HJELLE BRIAN , HALL PAM R , BROWN DAVID C , BISOFFI MARCO , BROZIK SUSAN M , BRANCH DARREN W , EDWARDS THAYNE L , WHEELER DAVID
IPC分类号： C12Q1/34 , C12M3/00
CPC分类号： G01N33/54373 , C12Q1/6825 , G01N29/032 , G01N33/553 , G01N2291/0422
摘要： Viruses and other bioagents are of high medical and biodefense concern and their detection at concentrations well below the threshold necessary to cause health hazards continues to be a challenge with respect to sensitivity, specificity, and selectivity. Ideally, assays for accurate and real time detection of viral agents and other bioagents would not necessitate any pre-processing of the analyte, which would make them applicable for example to bodily fluids (blood, sputum) and man-made as well as naturally occurring bodies of water (pools, rivers). We describe herein a robust biosensor that combines the sensitivity of surface acoustic waves (SAW) generated at a frequency of 325 MHz with the specificity provided by antibodies and other ligands for the detection of viral agents. In preferred embodiments, a lithium tantalate based SAW transducer with silicon dioxide waveguide sensor platform featuring three test and one reference delay lines was used to adsorb antibodies directed against Coxsackie virus B4 or the negative-stranded category A bioagent Sin Nombre virus (SNV), a member of the genus Hantavirus, family Bunyaviridae, negative-stranded RNA viruses. Rapid detection (within seconds) of increasing concentrations of viral particles was linear over a range of order of magnitude for both viruses, although the sensor was approximately 50x104 -fold more sensitive for the detection of SNV. For both pathogens, the sensor's selectivity for its target was not compromised by the presence of confounding Herpes Simplex virus type 1. The biosensor was able to detect SNV at doses lower than the load of virus typically found in a human patient suffering from hantavirus cardiopulmonary syndrome (HCPS). Further, in a proof-of-principle real world application, the SAW biosensor was capable of selectively detecting SNV agents in complex solutions, such as naturally occurring bodies of water (river, sewage effluent) without analyte pre-processing.
摘要翻译：病毒和其他生物制剂对医学和生物防御有很高的关注度，并且它们的检测浓度远低于引起健康危害所必需的阈值，这仍然是灵敏度，特异性和选择性方面的挑战。理想情况下，准确和实时检测病毒剂和其他生物剂的分析不需要对分析物进行任何预处理，这将使其适用于例如体液（血液，痰液）和人造以及自然发生的水体（水池，河流）。我们在此描述了一种鲁棒的生物传感器，其将频率为325MHz的表面声波（SAW）的灵敏度与由抗体和其他配体提供的用于检测病毒剂的特异性相结合。在优选的实施方案中，具有三个测试和一个参考延迟线的具有二氧化硅波导传感器平台的基于钽酸锂的SAW换能器被用于吸附针对柯萨奇病毒B4或负链A类生物因子Sin Nombre病毒（SNV）的抗体，a 汉坦病毒属，布尼亚病毒科，负链RNA病毒成员。对于两种病毒，增加浓度的病毒颗粒的快速检测（数秒内）在一定数量级范围内是线性的，尽管对于检测SNV而言传感器的灵敏度约为50×10 4倍。对于这两种病原体而言，传感器对其靶标的选择性不会由于混杂的1型单纯性疱疹病毒的存在而受到损害。生物传感器能够以比通常在患有汉坦病毒心肺综合征的人类患者中发现的病毒载量低的剂量检测SNV （HCPS）。此外，在原理验证的实际应用中，SAW生物传感器能够选择性检测复杂溶液中的SNV试剂，例如没有分析物预处理的天然存在的水体（河流，污水流出物）。

2. 发明公开

EP2158384A4 FUEL APPARATUS AND METHOD 审中-公开
标题翻译：维也纳公民组织（BRENNSTOFFVORRICHTUNG UND ENTSPRECHENDES VERFAHREN）
公开(公告)号：EP2158384A4
公开(公告)日：2011-10-26
申请号：EP08771904
申请日：2008-06-25
申请人： WHEELER DAVID , KOSZTOLANYI NORA
发明人： WHEELER DAVID , KOSZTOLANYI NORA
IPC分类号： F02B15/00
CPC分类号： F02B51/00 , F02M27/00

3. 发明申请

WO2007008328A3 APPARATUS AND METHOD OF MAKING TRANSFORMED WATER 审中-公开
标题翻译：装置和制造变压水的方法
公开(公告)号：WO2007008328A3
公开(公告)日：2008-06-12
申请号：PCT/US2006023028
申请日：2006-06-13
申请人： WHEELER DAVID , KOSZTOLANYI NORA
发明人： WHEELER DAVID , KOSZTOLANYI NORA
IPC分类号： C02F1/00 , C02F3/00 , C02F5/00
CPC分类号： A61K33/00 , C02F1/005
摘要： The present invention provides an apparatus and method of producing transformed water without contact between the original transformed water and the water to be transformed. This is accomplished by organizing the original transformed water into a geometric contained arrange¬ ment such that a central cavity is created that substantially surrounds the water that is to be transformed. The water to be transformed is placed into a confined vessel such as a cylindrical container or a pipe inside the central cavity for about sixty seconds. This water then becomes transformed in the same likeness of the molecular clustering of the original transformed water.
摘要翻译：本发明提供一种在原始转化水和待转化水之间不产生转化水的方法。这是通过将原始转化的水组织成几何包含的布置来实现的，使得产生基本上围绕待转化的水的中心腔。将待转化的水置于密封容器中，如圆筒形容器或中心腔内的管道中约六十秒。然后，水以与原始转化水的分子聚类相同的相似方式变换。

4. 发明专利

CA2773431A1 WINDSHIELD WASHER FLUID DISPENSER 未知
公开(公告)号：CA2773431A1
公开(公告)日：2010-10-21
申请号：CA2773431
申请日：2010-04-13
申请人： WHEELER LOYDE A , WHEELER DAVID , WHEELER CYNTHIA
发明人： WHEELER LOYDE A , WHEELER DAVID , WHEELER CYNTHIA
IPC分类号： B65B1/04
摘要： A windshield washer fluid dispenser providing a delayed start function, whereby the user can open the hood of their vehicle and cap to their fluid reservoir. A windshield washer fluid dispenser utilizing a cellular credit card processing system for payment means, whereby the processing system is configurable for a given application. Embodiments with proximity device, RFID and wireless telephone verification are included. A windshield washer fluid dispenser having a ready light, a warning light, a start button, a flow meter and a programmable logic circuit. A windshield washer fluid dispenser system providing for a replaceable fluid drum. Methods pertaining to the disclosed apparatus are also provided.

5. 发明申请

WO2009056157A8 MODULAR SYSTEM FOR THE PRODUCTION OF SOCKETS 审中-公开
标题翻译：模块化系统的储层网点
公开(公告)号：WO2009056157A8
公开(公告)日：2010-04-01
申请号：PCT/EP2007009503
申请日：2007-11-02
申请人： ABB PATENT GMBH , WHEELER DAVID , DELAMONT CHRISTOPHER
发明人： WHEELER DAVID , DELAMONT CHRISTOPHER
IPC分类号： H01R27/00 , H01R13/453 , H01R31/06 , H02G3/18
CPC分类号： H02G3/18 , H01R13/4532 , H01R13/506 , H01R24/78 , H01R27/00 , H01R31/06 , H01R2103/00
摘要： Disclosed is a modular system for producing sockets meeting different country-specific standards. Said modular system has the following structural components: a base (2) of a socket insert (1, 23, 30, 36) comprising three chambers for inserting differently designed electrical contacts (5, 24, 39) and chambers for accommodating terminal clamps (8), said base (2) being identical for all sockets; at least one base cover (3, 25, 37) of a socket insert (1, 23, 30, 36) with recesses (4, 26, 38) which allow plug pins to engage therein and are suitable for a plurality of different plugs with different plug pins according to different country-specific standards; at least one support plate (10, 31) that can be optionally mounted on the base (2); a plurality of different front covers (11-20, 27, 42-45), each of which has recesses (21, 28, 46) allowing pins of a plug according to a certain country-specific standard to engage therein; a front cover (11-20, 27, 42-45) is mounted on the socket insert (1, 23, 30, 36) with the help of corresponding locking means (52, 55).
摘要翻译：公开的是用于不同国家的特定标准插座，由下列结构组分的形成的模块化系统：一个相等的插座插入件（1，23，30，36），其具有三个腔室的所有插座的基体（2）（用于插入不同形状的电触点 5，24，39）和腔室，用于接收端子的插座的插入件（1，23，30（8），至少一个主体盖（3，25，37），36）与凹部（4，26，38）对于塞的塞销的卡合，所述凹部（4，26，38）是普遍适用于各种具有根据不同的插头管脚与差工会特定国家的标准不同的状态，在基体上的至少一个（2）任选地安装支承板（10，31不同的连接器的），多个不同的前盖（11 - 20，27，42 - 45），每个凹部（21，28，46）根据一个特定状态的特定国家特定标准，具有与插头的插头插脚接合的m，其中的前盖的安装（11 - 20，27，42 - 45）在插座插入件（1，23，30，36）由相互对应的锁定装置（52， 55）进行。

6. 发明申请

WO2005060151A2 TRUSTED MOBILE PLATFORM ARCHITECTURE 审中-公开
标题翻译： TRUSTED移动平台架构
公开(公告)号：WO2005060151A2
公开(公告)日：2005-06-30
申请号：PCT/US2004041909
申请日：2004-12-13
申请人： INTEL CORP , WHEELER DAVID , BRIZEK JOHN , KHAN MOINUL , KONA ANITHA
发明人： WHEELER DAVID , BRIZEK JOHN , KHAN MOINUL , KONA ANITHA
IPC分类号： H04L9/08
CPC分类号： H04L9/088 , G06F21/575 , G06F21/72 , G06F2221/2103 , H04L9/0822 , H04L2209/80 , H04W12/10
摘要： In an embodiment, an apparatus includes one or more cryptographic units. The apparatus also includes a memory to store one or more data encryption keys and an associated header for the one or more data encryption keys. The associated header defines which of the one or more cryptographic units are to use the data encryption key.
摘要翻译：在一个实施例中，装置包括一个或多个加密单元。该装置还包括用于存储一个或多个数据加密密钥的存储器和用于一个或多个数据加密密钥的关联报头。相关联的报头定义一个或多个加密单元中的哪一个将使用数据加密密钥。

7. 发明申请

WO2009003020A3 FUEL APPARATUS AND METHOD 审中-公开
标题翻译：燃料装置和方法
公开(公告)号：WO2009003020A3
公开(公告)日：2009-02-26
申请号：PCT/US2008068158
申请日：2008-06-25
申请人： WHEELER DAVID , KOSZTOLANYI NORA
发明人： WHEELER DAVID , KOSZTOLANYI NORA
IPC分类号： F02B15/00
CPC分类号： F02B51/00 , F02M27/00
摘要： An apparatus and method of enhancing fuel combustion by organizing an amount of transformed water with a high level of stored energy into a geometric arrangement such that a central cavity is created that substantially surrounds a segment of a fuel line leading to a combustion device such as an internal combustion engine. The fuel passes within the space surrounded by the transformed water and becomes imprinted with a molecular clustering as a result of water memory transfer at a lower level of stored energy. This process alter the properties of the fuel allowing it to be utilized with a higher level of efficiency and with lower emissions of pollutants such as hydrocarbons and carbon monoxide.
摘要翻译：通过将具有高水平储存能量的转化水组织到几何布置中来增强燃料燃烧的装置和方法，使得形成基本上围绕通向燃烧装置（例如，内燃机。燃料在被转化的水包围的空间内通过，并且由于在较低储存能量水平下的水分记录传递而被分子聚集印迹。该方法改变了燃料的性质，使其能够以更高的效率和更低的污染物排放（如碳氢化合物和一氧化碳）被利用。

8. 发明申请

WO9925085B1 METHOD AND APPARATUS FOR PERFORMING SERVICE LEVEL ANALYSIS OF COMMUNICATIONS NETWORK PERFORMANCE METRICS 审中-公开
标题翻译：用于执行通信网络性能指标的服务水平分析的方法和设备
公开(公告)号：WO9925085B1
公开(公告)日：1999-07-29
申请号：PCT/US9823891
申请日：1998-11-06
申请人： VISUAL NETWORKS INC , DRYSDALE R SCOTT , ENNIS JAMES D JR , HASSELKUS JOHN E , NISBET THOMAS R , TROUTMAN ROBERT C , REHBEHN KEN , WHEELER DAVID
发明人： DRYSDALE R SCOTT , ENNIS JAMES D JR , HASSELKUS JOHN E , NISBET THOMAS R , TROUTMAN ROBERT C , REHBEHN KEN , WHEELER DAVID
IPC分类号： H04L1/24 , H04L12/24 , H04L12/26 , H04L12/56 , H04Q11/04 , H04J3/14
CPC分类号： H04L43/12 , H04L1/24 , H04L41/00 , H04L41/5009 , H04L41/5019 , H04L41/5038 , H04L43/062 , H04L43/0811 , H04L43/0829 , H04L43/0864 , H04L43/0888 , H04L43/106 , H04L2012/5628 , H04L2012/5647 , H04L2012/5649 , H04Q11/0478
摘要： A data transmission system includes probes (probe A, probe B) connected between end user sites (site A, site B) and a data switching network (12). Each probe is connected to the switching network (12) via an access channel (20, 21, 26 or 27) wherein transmission circuits establish paths between the sites through the access channel (20, 21, 26 or 27) and switching network (12). The probes capture and retransmit data traveling between the sites over respective transmission circuits, and can thereby insert service level anaylsis (SLA) messages into data traffic in order to actively communicate network performance information to other probes. For each transmission circuit, the probes periodically collect measurements related to one or more network performance metrics, including round-trip delay (RTD), data delivery ratio (DDR) and network availability. During each SLA measurement cycle, a sequence of SLA messages is exchanged over each transmission circuit, which messages contain data used to determine RTD and DDR.
摘要翻译：数据传输系统包括连接在终端用户站点（站点A，站点B）和数据交换网络（12）之间的探针（探针A，探针B）。每个探测器经由接入信道（20,21,26或27）连接到交换网络（12），其中传输电路通过接入信道（20,21,26或27）和交换网络（12 ）。探测器通过各自的传输电路捕获和重传在站点之间传播的数据，并且因此可以将服务级别分析（SLA）消息插入到数据业务中以便主动将网络性能信息传送给其他探测。对于每个传输电路，探针周期性地收集与一个或多个网络性能指标（包括往返延迟（RTD），数据传输率（DDR）和网络可用性）相关的测量。在每个SLA测量周期中，在每个传输电路上交换一系列SLA消息，该消息包含用于确定RTD和DDR的数据。

9. 发明专利

BRPI0810337A2 未知
公开(公告)号：BRPI0810337A2
公开(公告)日：2014-10-14
申请号：BRPI0810337
申请日：2008-06-25
申请人： WHEELER DAVID , KOSZTOLANYI NORA
发明人： WHEELER DAVID , KOSZTOLANYI NORA
IPC分类号： F02B15/00
摘要： An apparatus and method of enhancing fuel combustion by organizing an amount of transformed water with a high level of stored energy into a geometric arrangement such that a central cavity is created that substantially surrounds a segment of a fuel line leading to a combustion device such as an internal combustion engine. The fuel passes within the space surrounded by the transformed water and becomes imprinted with a molecular clustering as a result of water memory transfer at a lower level of stored energy. This process alter the properties of the fuel allowing it to be utilized with a higher level of efficiency and with lower emissions of pollutants such as hydrocarbons and carbon monoxide.

10. 发明专利

MX2009012496A APARATO Y METODO DE COMBUSTIBLE. 未知
公开(公告)号：MX2009012496A
公开(公告)日：2010-03-30
申请号：MX2009012496
申请日：2008-06-25
申请人： WHEELER DAVID
发明人： WHEELER DAVID , KOSZTOLANYI NORA
IPC分类号： F02B15/00
摘要： Un aparato y un método para mejorar la combustión de combustible organizando una cantidad de agua transformada con un alto nivel de energía almacenada en un arreglo geométrico de manera que se crea una cavidad central que rodea substancialmente un segmento de una línea de combustible que conduce a un dispositivo de combustión tal como un motor de combustión interna. El combustible pasa dentro del espacio rodeado por el agua transformada y se imprime con racimo molecular como resultado de la transferencia de memoria de agua en un nivel inferior de energía almacenada. Este proceso altera las características del combustible permitiendo que sea utilizado con un nivel superior de eficacia y con emisiones más bajas de agentes contaminantes tales como hidrocarburos y monóxido de carbono.

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