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1. 发明专利

AT309810T 未知
公开(公告)号：AT309810T
公开(公告)日：2005-12-15
申请号：AT00106844
申请日：2000-03-30
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TAKADA YUKIHIRO , SERIZAWA ATSUSHI , ISHIKAWA HIDETOSHI , YOSHIOKA TOMOE , AOE SEIICHIRO
IPC分类号： A23C9/13 , A23C19/084 , A23G4/00 , A23G4/12 , A23G4/14 , A23L2/38 , A23L2/52 , A23L2/66 , A23L2/78 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/59 , A61K33/06 , A61K35/20 , A61K38/55 , A61P1/00 , A61P1/02 , A61P19/00 , A61P19/08 , A61P19/10 , A61P43/00
摘要： A highly safe bone resorption suppressing agent, which can be used as medicine or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

2. 发明专利

DK1040833T3 未知
公开(公告)号：DK1040833T3
公开(公告)日：2005-12-12
申请号：DK00106844
申请日：2000-03-30
申请人： SNOW BRAND MILK PROD CO LTD
发明人： SERIZAWA ATSUSHI , YOSHIOKA TOMOE , TAKADA YUKIHIRO , ISHIKAWA HIDETOSHI , AOE SEIICHIRO
IPC分类号： A23C9/13 , A23C19/084 , A23G4/00 , A23G4/12 , A23G4/14 , A23L2/38 , A23L2/52 , A23L2/66 , A23L2/78 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/59 , A61K33/06 , A61K35/20 , A61K38/55 , A61P1/00 , A61P1/02 , A61P19/00 , A61P19/08 , A61P19/10 , A61P43/00
摘要： A highly safe bone resorption suppressing agent, which can be used as medicine or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

3. 发明专利

AU771583B2 Bone resorption suppressing agent 未知
公开(公告)号：AU771583B2
公开(公告)日：2004-03-25
申请号：AU2263300
申请日：2000-03-28
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TAKADA YUKIHIRO , SERIZAWA ATSUSHI , ISHIKAWA HIDETOSHI , YOSHIOKA TOMOE , AOE SEIICHIRO
IPC分类号： A23C9/13 , A23C19/084 , A23G4/00 , A23G4/12 , A23G4/14 , A23L2/38 , A23L2/52 , A23L2/66 , A23L2/78 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/59 , A61K33/06 , A61K35/20 , A61K38/55 , A61P1/00 , A61P1/02 , A61P19/00 , A61P19/08 , A61P19/10 , A61P43/00 , A23L1/305
摘要： A highly safe bone resorption suppressing agent, which can be used as medicine or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

4. 发明专利

DE69411073T2 未知
公开(公告)号：DE69411073T2
公开(公告)日：1998-10-15
申请号：DE69411073
申请日：1994-04-16
申请人： SNOW BRAND MILK PROD CO LTD
发明人： ITAGAKI YASUHARU , ISHIKAWA HIDETOSHI , KUROSAWA SEIJI
IPC分类号： A61K8/72 , A61K8/00 , A61K8/64 , A61K8/96 , A61K8/98 , A61Q19/00 , A61Q19/02 , A61Q19/10 , A61K7/48
摘要： A whitening cosmetic preparation containing angiogenin as an effective component is disclosed. Angiogenin used in the present invention may be derived from milk, especially bovine milk. The whitening cosmetic preparation contains at least 0.001% by weight, preferably from 0.01 to 20% by weight angiogenin based on the total amount of said preparation. A method for whitening skin comprising administration of angiogenin to skin is also disclosed. The whitening cosmetic preparation inhibits melanin production and prevents the developments of blotches and freckles of skin.

5. 发明专利

JPH08283162A MINERAL ABSORPTION PROMOTER 失效
公开(公告)号：JPH08283162A
公开(公告)日：1996-10-29
申请号：JP8372895
申请日：1995-04-10
申请人： SNOW BRAND MILK PROD CO LTD
发明人： YANAGIDAIRA SHUICHI , MATSUBARA NORINOBU , IKEUCHI YOSHIHIRO , YABE KYOKO , ISHIKAWA HIDETOSHI , KATO TAKESHI
IPC分类号： A61K31/70 , A61K31/7008 , A61P3/00 , A61P3/14 , C07H5/06 , A23K1/175 , A23K1/20
摘要： PURPOSE: To obtain a mineral absorption promoter comprising sialyllactose or its acid addition salt as an active ingredient. CONSTITUTION: This mineral absorption promoter comprises sialyllactose shown by the general formula Neu5Ac α 2-3Galβ1-4Glc, Neu5Ac a 2-6Galβ1 4Glc, etc., or its acid addition salt as an active ingredient. The mineral absorption promoter is taken as a food and beverage and a medicine so that symptoms such as osteoporosis, iron deficiency, etc., can be improved. The mineral absorption promoter can be mixed in a feed for domestic animals.

6. 发明专利

JPS55110195A MANUFACTURE OF REFORMED PALM OIL 失效
公开(公告)号：JPS55110195A
公开(公告)日：1980-08-25
申请号：JP1813879
申请日：1979-02-19
申请人： NISSHIN OIL MILLS LTD , SNOW BRAND MILK PROD CO LTD
发明人： HAMASHIMA MORIO , FUJIKAWA TAKUMA , ISHIKAWA HIDETOSHI , KONDOU SATOSHI
IPC分类号： C11C3/10

7. 发明专利

ES2249207T3 AGENTE DE SUPRESION DE LA RESORCION OSEA. 未知
公开(公告)号：ES2249207T3
公开(公告)日：2006-04-01
申请号：ES00106844
申请日：2000-03-30
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TAKADA YUKIHIRO , SERIZAWA ATSUSHI , ISHIKAWA HIDETOSHI , YOSHIOKA TOMOE , AOE SEIICHIRO
IPC分类号： A23C9/13 , A23C19/084 , A23G4/00 , A23G4/12 , A23G4/14 , A23L2/38 , A23L2/52 , A23L2/66 , A23L2/78 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/59 , A61K33/06 , A61K35/20 , A61K38/55 , A61P1/00 , A61P1/02 , A61P19/00 , A61P19/08 , A61P19/10 , A61P43/00
摘要： Un agente de supresión de la resorción ósea que comprende una cistatina básica derivada de la leche y/o el producto de descomposición de cistatina básica derivada de la leche como un componente eficaz, siendo dicha cistatina básica derivada de la leche una proteína obtenible por un procedimiento que comprende (i) pasar leche desnatada de vaca a través de una columna de S-sefarosa; (ii) lavar la columna con agua desionizada; (iii) eluir una fracción de la columna usando un gradiente de concentración lineal de 0, 1 a 1, 0 M de cloruro de sodio; (iv) calentar la fracción eluida hasta 90 ºC durante 10 minutos; (v) centrifugar la fracción eluida para eliminar precipitados, creando de esta manera una primera fracción; (vi) fraccionar la primera fracción usando cromatografía de intercambio iónico MonoS, creando así una segunda fracción; (vii) fraccionar la segunda fracción usando cromatografía de intercambio iónico MonoQ y cromatografía de filtración con gel Superose 12 con un sistema HPLC, posteriormente con cromatografía con hidroxiapatita y cromatografía de fase inversa C4 usando un sistema HPLC, o por un procedimiento que comprende (I) calentar una solución de proteína de suero de leche de vaca al 5% a 90 ºC durante 10 minutos; (II) centrifugar la solución para eliminar precipitados, creando así una primera fracción; (III) pasar la primera fracción a través de una columna llena con un vehículo en el que papaína carboximetilada está unida a Tresyl-Toyopearl y equilibrada con una solución de cloruro de sodio 0, 5 M; (IV) lavar la columna con una solución de cloruro de sodio 0, 5 M y luego con una solución de cloruro de sodio 0, 5 M que contiene 0, 1% de Tween 20; (V) eluir la proteasa de cisteína con una solución de cloruro de sodio 0, 5 M-ácido acético 20 mM; (VI) neutralizar la fracción eluida con una solución de hidróxido de sodio 1 M, creando así una segunda fracción; y (VII) fraccionar la segunda fracción usando cromatografía de intercambio aniónico MonoS, posteriormente cromatografía con hidroxiapatita y cromatografía de fase inversa C4 usando un sistema HPLC.

8. 发明专利

DE69411073D1 未知
公开(公告)号：DE69411073D1
公开(公告)日：1998-07-23
申请号：DE69411073
申请日：1994-04-16
申请人： SNOW BRAND MILK PROD CO LTD
发明人： ITAGAKI YASUHARU , ISHIKAWA HIDETOSHI , KUROSAWA SEIJI
IPC分类号： A61K8/72 , A61K8/00 , A61K8/64 , A61K8/96 , A61K8/98 , A61Q19/00 , A61Q19/02 , A61Q19/10 , A61K7/48
摘要： A whitening cosmetic preparation containing angiogenin as an effective component is disclosed. Angiogenin used in the present invention may be derived from milk, especially bovine milk. The whitening cosmetic preparation contains at least 0.001% by weight, preferably from 0.01 to 20% by weight angiogenin based on the total amount of said preparation. A method for whitening skin comprising administration of angiogenin to skin is also disclosed. The whitening cosmetic preparation inhibits melanin production and prevents the developments of blotches and freckles of skin.

9. 发明专利

DE60023972T2 未知
公开(公告)号：DE60023972T2
公开(公告)日：2006-08-10
申请号：DE60023972
申请日：2000-03-30
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TAKADA YUKIHIRO , SERIZAWA ATSUSHI , ISHIKAWA HIDETOSHI , YOSHIOKA TOMOE , AOE SEIICHIRO
IPC分类号： A23C9/13 , A61K35/20 , A23C19/084 , A23G4/00 , A23G4/12 , A23G4/14 , A23L2/38 , A23L2/52 , A23L2/66 , A23L2/78 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/59 , A61K33/06 , A61K38/55 , A61P1/00 , A61P1/02 , A61P19/00 , A61P19/08 , A61P19/10 , A61P43/00
摘要： A highly safe bone resorption suppressing agent, which can be used as medicine or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

10. 发明专利

DE60023972D1 未知
公开(公告)号：DE60023972D1
公开(公告)日：2005-12-22
申请号：DE60023972
申请日：2000-03-30
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TAKADA YUKIHIRO , SERIZAWA ATSUSHI , ISHIKAWA HIDETOSHI , YOSHIOKA TOMOE , AOE SEIICHIRO
IPC分类号： A23C9/13 , A23C19/084 , A23G4/00 , A23G4/12 , A23G4/14 , A23L2/38 , A23L2/52 , A23L2/66 , A23L2/78 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/59 , A61K33/06 , A61K35/20 , A61K38/55 , A61P1/00 , A61P1/02 , A61P19/00 , A61P19/08 , A61P19/10 , A61P43/00
摘要： A highly safe bone resorption suppressing agent, which can be used as medicine or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

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