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1. 发明申请

WO2012047945A2 WEAR RESISTANT COATING, ARTICLE, AND METHOD 审中-公开
标题翻译：耐磨涂层，文章和方法
公开(公告)号：WO2012047945A2
公开(公告)日：2012-04-12
申请号：PCT/US2011054835
申请日：2011-10-05
申请人： SILCOTEK CORP , SMITH DAVID A , MATTZELA JAMES B , SILVIS PAUL H , BARONE GARY A , HIGGINS MARTIN E
发明人： SMITH DAVID A , MATTZELA JAMES B , SILVIS PAUL H , BARONE GARY A , HIGGINS MARTIN E
IPC分类号： C23C16/02
CPC分类号： C09D5/00 , C23C16/0272 , C23C16/18 , C23C16/30 , C23C16/401 , C23C16/56 , C23C30/00 , Y10T428/265 , Y10T428/31612 , Y10T428/31663
摘要： A wear coating is disclosed that includes a layer treated by a trifunctional organosilane. An article is also disclosed, the article having a surface to which the wear coating is applied. A method of applying the wear coating is also disclosed. In some embodiments, the organosilane is trimethylsilane and the wear coating is applied by chemical vapor deposition, followed by heat treating the wear coating in the presence of the trimethylsilane.
摘要翻译：公开了一种耐磨涂层，其包括由三官能有机硅烷处理的层。还公开了一种制品，其具有施加耐磨涂层的表面。还公开了施加耐磨涂层的方法。在一些实施方案中，有机硅烷是三甲基硅烷，并且通过化学气相沉积施加耐磨涂层，然后在三甲基硅烷存在下对耐磨涂层进行热处理。

2. 发明公开

EP0590066A4 METHOD FOR INDUCING HUMAN MYOCARDIAL CELL PROLIFERATION. 失效
标题翻译：方法人民币人民币升值。
公开(公告)号：EP0590066A4
公开(公告)日：1994-12-07
申请号：EP92914425
申请日：1992-06-11
申请人： SMITH DAVID A , TOWNSEND LAURACE , NEWMAN DAWN , DUFF RONALD S
发明人： SMITH DAVID A , TOWNSEND LAURACE , NEWMAN DAWN , DUFF RONALD S
IPC分类号： C12N5/077 , C12N5/00 , A61K35/14
CPC分类号： C12N5/0657 , C12N2502/11
摘要： The present invention provides for a method for inducing myocardial cell proliferation, as well as for myocardial cell cultures produced by this method. The method is based on the discovery that adult human myocardial cells may be induced to proliferate in culture by exposure to a platelet freeze/thaw extract. In a preferred embodiment the myocardial cells are adult human atrial myocardial cells.
摘要翻译：本发明涉及诱导心肌细胞增殖的方法。至少部分地基于这样的发现，即通过暴露于血小板冻融提取物可以诱导成体人心肌细胞在培养物中增殖。本发明提供了一种用于在体外诱导心肌细胞增殖的方法，以及通过该方法产生的心肌细胞培养物。在优选的实施方案中，本发明提供人心肌细胞培养物。本发明的心肌细胞培养物可用于研究心肌的生理学。此外，它们可以用于鉴定可用于治疗心脏病的药剂，或者是心脏毒性的药剂。此外，本发明的培养物可以用于提供可以移植或植入患有心脏病症的患者中的心肌细胞。在另外的实施方案中，本发明还提供在体内诱导心肌细胞增殖的方法。这些方法可用于治疗患有心脏病的患者，特别是那些已经受到心肌组织损伤或损失的患者。

3. 发明申请

WO2014011251A2 COATED ARTICLE AND CHEMICAL VAPOR DEPOSITION PROCESS 审中-公开
标题翻译：涂层制品和化学气相沉积工艺
公开(公告)号：WO2014011251A2
公开(公告)日：2014-01-16
申请号：PCT/US2013033807
申请日：2013-03-26
申请人： SILCOTEK CORP
发明人： SMITH DAVID A
IPC分类号： B32B15/082
CPC分类号： B05D1/60 , C23C16/0209 , C23C16/0272 , C23C16/46 , Y10T428/31544 , Y10T428/31663
摘要： A coated article and a chemical vapor deposition process are disclosed. The coated article includes a functionalized layer applied to the coated article by chemical vapor deposition. The functionalized layer is a layer selected from the group consisting of an oxidized-then-functionalized layer, an organofluoro treated layer, a fluorosilane treated layer, a trimethylsilane treated surface, an organofluorotrialkoxysilanes treated layer, an organofluorosilylhydrides-treated layer, an organofluoro silyl treated layer, a tridecafluoro 1,1,2,2-tetrahydrooctylsilane treated layer, an organofluoro alcohol treated layer, a pentafluoropropanol treated layer, an allylheptafluoroisopropyl ether treated layer, a (perfluorobutyl) ethylene treated layer, a (perfluorooctyl) ethylene treated layer, and combinations thereof. The process includes applying the functionalized layer.
摘要翻译：公开了涂覆制品和化学气相沉积工艺。涂覆制品包括通过化学气相沉积施加到涂覆制品上的官能化层。官能化层是选自由氧化后功能化层，有机氟化处理层，氟硅烷处理层，三甲基硅烷处理表面，有机氟三烷氧基硅烷处理层，有机氟甲硅烷基氢化物处理层，有机氟甲硅烷基处理层（全氟丁基）乙烯处理层，（全氟辛基）乙烯处理层，以及（全氟辛基）乙烯处理层，和（全氟丁基）乙烯处理层，它们的组合。该过程包括应用功能化层。

4. 发明专利

ES2859458T3 Recubrimiento, artículo y método de deposición química de vapor 未知
公开(公告)号：ES2859458T3
公开(公告)日：2021-10-04
申请号：ES10771619
申请日：2010-10-26
申请人： SILCOTEK CORP
发明人： SMITH DAVID A , MATTZELA JAMES B , SILVIS PAUL H , BARONE GARY A
IPC分类号： C23C16/32 , B05D7/24 , C23C8/10 , C23C16/56
摘要： Un método (200) de deposición química de vapor térmica, comprendiendo el método (200): la preparación de (202) un sustrato (100) en una cámara de deposición química de vapor; la descomposición térmica (204) de dimetilsilano en la cámara de deposición química de vapor para formar un recubrimiento (102), realizándose la descomposición térmica en ausencia de energías de deposición adicionales, tales como campos de plasma y microondas, y en las siguientes condiciones: - a una presión de entre 6,8948x10-3 MPa (6,8948x10-2 bar (1,0 l.p.c.a.)) y 0,68948 MPa (6,8948 bar (100 l.p.c.a.)), preferentemente a una presión de entre 3,4474x10-2 MPa (3,4474x10-1 bar (5 l.p.c.a.)) y aproximadamente 0,27579 MPa (2,7579 bar (40 l.p.c.a.)); y - a una temperatura de entre 300 °C y 600 °C; y - durante un tiempo de 30 minutos a 24 horas.

5. 发明专利

AU2016253571A1 Thermal chemical vapor deposition split-functionalization process, product, and coating 未知
公开(公告)号：AU2016253571A1
公开(公告)日：2017-05-25
申请号：AU2016253571
申请日：2016-11-02
申请人： SILCOTEK CORP
发明人： YUAN MIN , SILVIS PAUL H , SMITH DAVID A , MATTZELA JAMES B
IPC分类号： C23C16/00
摘要： THERMAL CHEMICAL VAPOR DEPOSITION SPLIT FUNCTIONALIZATION PROCESS, PRODUCT, AND COATING Thermal chemical vapor deposition split-functionalizing processes, coatings, and products are disclosed. The thermal chemical vapor deposition split-functionalizing process includes positioning an article within an enclosed chamber, functionalizing the article within a first temperature range for a first period of time, and then further functionalizing the article within a second temperature range for a second period of time. The thermal chemical vapor deposition split-functionalized product includes a functionalization formed by functionalizing within a first temperature range for a first period of time and a further functionalization formed by further functionalizing within a second temperature range for a second period of time. -12-

6. 发明专利

AU2017276352A1 Fluoro-containing thermal chemical vapor deposition process and article 未知
公开(公告)号：AU2017276352A1
公开(公告)日：2019-07-04
申请号：AU2017276352
申请日：2017-12-15
申请人： SILCOTEK CORP
发明人： SMITH DAVID A
IPC分类号： C23C16/44 , C23C16/22
摘要： Thermal chemical vapor deposition treatment is disclosed. Specifically, a thermal chemical vapor deposition treated article includes a substrate, and an oleophobic treatment to the substrate, the oleophobic treatment having oxygen, carbon, silicon, fluorine, and hydrogen. The oleophobic treatment has a treatment thickness of less than 600 nm and a heterogeneous wetting regime. The thermal chemical vapor deposition process includes positioning an article within a thermal chemical vapor deposition chamber, thermally reacting dimethylsilane to produce a layer, oxidizing the layer to produce an oxidized layer, and fluoro-functionalizing the oxidized layer to produce an oxidized then fluoro-functionalizing dimethylsilane chemical vapor deposition treatment. The oxidized then fluoro-functionalizing dimethylsilane chemical vapor deposition treatment has a treatment thickness of less than 600 nm and a heterogeneous wetting regime. -18- N In T-1 oli -4 (H .-1 r-0 C)1

7. 发明专利

CA2962318A1 TREATED ARTICLE, SYSTEM HAVING TREATED ARTICLE, AND PROCESS INCORPORATING TREATED ARTICLE 未知
公开(公告)号：CA2962318A1
公开(公告)日：2017-09-29
申请号：CA2962318
申请日：2017-03-28
申请人： SILCOTEK CORP
发明人： SMITH DAVID A
IPC分类号： C23C8/28 , C10G75/04 , C22C19/05 , C22C21/00 , C22C38/18 , C22C38/22 , C23F14/02 , F16L58/04 , F28F19/02
摘要： Treated articles and a process of producing the treated articles, systems having treated articles, and processes incorporating treated articles are disclosed. The treated articles include a metal or metallic substrate, and a surface treatment of the metal or metallic substrate, the surface treatment having fluorine, silicon, and carbon. The systems include a flow path, with the surface treatment being within the flow path. The processes include flowing a fluid through the flow path.

8. 发明申请

WO2009046439A3 DUAL RESERVOIR IMPLANTABLE ACCESS PORT 审中-公开
标题翻译：双存储可入口访问端口
公开(公告)号：WO2009046439A3
公开(公告)日：2009-05-22
申请号：PCT/US2008078976
申请日：2008-10-06
申请人： ANGIODYNAMICS INC , HANSON BARRY , KEESE BRIAN , SMITH DAVID A , FOWLER MICHAEL , JOHNSON BLAINE , RECINELLA DANIEL K , KENNY STEVE
发明人： HANSON BARRY , KEESE BRIAN , SMITH DAVID A , FOWLER MICHAEL , JOHNSON BLAINE , RECINELLA DANIEL K , KENNY STEVE
IPC分类号： A61M39/02 , A61M5/32
CPC分类号： A61M39/0208 , A61M2039/0211 , A61M2039/0232 , A61M2039/0238
摘要： An implantable access port for use in transferring fluid transdermally between an external fluid storage or dispensing device and a site within a patient is disclosed. The access port includes a body, at least two reservoirs defined within the access port body, and at least one septum secured to the body and enclosing the reservoirs within the body. The access port also includes reservoir outlets defined within the reservoirs. The access port also has body conduits defined within the body and in fluid communication with the reservoir outlets and external openings defined in the exterior of the body. An implantable access port and system for use in apheresis is also provided that includes an implantable access port, at least one needle, and a catheter that is fluidly connected to the access port.
摘要翻译：公开了一种用于在外部流体存储或分配装置和患者内的部位之间经皮转运流体的可植入进入口。进入端口包括主体，限定在进入端口主体内的至少两个储存器，以及固定到主体上并且将储存器封闭在主体内的至少一个隔膜。进出口还包括限定在储存器内的储存器出口。进入口还具有限定在主体内并与储存器出口和限定在身体外部的外部开口流体连通的体导管。还提供了一种用于单采血液成像术的可植入进入口和系统，其包括可植入进入口，至少一个针和与流体连接到进入口的导管。

9. 发明专利

CA2111347A1 METHOD FOR INDUCING HUMAN MYOCARDIAL CELL PROLIFERATION 未知
公开(公告)号：CA2111347A1
公开(公告)日：1992-12-23
申请号：CA2111347
申请日：1992-06-11
申请人： SMITH DAVID A , TOWNSEND LAURACE , NEWMAN DAWN , DUFF RONALD S
发明人： SMITH DAVID A , TOWNSEND LAURACE , NEWMAN DAWN , DUFF RONALD S
IPC分类号： C12N5/077 , C12N5/02 , C12N5/08 , A61K35/14
摘要： 2111347 9222636 PCTABScor01 The present invention provides for a method for inducing myocardial cell proliferation, as well as for myocardial cell cultures produced by this method. The method is based on the discovery that adult human myocardial cells may be induced to proliferate in culture by exposure to a platelet freeze/thaw extract. In a preferred embodiment the myocardial cells are adult human atrial myocardial cells.

10. 发明授权

US3866074A Magnetic spark spreader 失效
标题翻译： MAGNETIC SPARK SPREADER
公开(公告)号：US3866074A
公开(公告)日：1975-02-11
申请号：US38189873
申请日：1973-07-23
申请人： SMITH DAVID A
发明人： SMITH DAVID A
IPC分类号： H01T13/41 , H01T13/42 , H01T13/04
CPC分类号： H01T13/41
摘要： A spark plug having a superimposed magnetic field for use in internal combustion engines is disclosed. A magnetic field generator, such as a magnet, is disposed in proximity to the anode of the spark plug. The magnet produces a magnetic field which field alters the conductive properties of the envelope surrounding the anode and cathode electrodes. The resultant nonisotropic conductivity, in turn, promotes a larger arc envelope or plasma and hence a better probability of ignition of the combustible mixture within the engine.

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