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1. 发明申请

WO2007127382A1 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 审中-公开
标题翻译：羟基取代的氨基酸，其组合物及其处理方法
公开(公告)号：WO2007127382A1
公开(公告)日：2007-11-08
申请号：PCT/US2007/010258
申请日：2007-04-25
申请人： SIGNAL PHARMACEUTICALS, LLC , ALBERS, Ronald, J. , AYALA, Leticia , CLAREEN, Steven, S. , DELGADO MEDEROS, Maria, Mercedes , HILGRAF, Robert , HEGDE, Sayee, G. , HUGHES, Kevin , KOIS, Adam , PLANTEVIN-KRENITSKY, Veronique , MCCARRICK, Meg , NADOLNY, Lisa , PALANKI, Moorthy, S.S. , SAHASRAMUDHE, Kiran , SAPIENZA, John , SATOH, Yoshitaka , SLOSS, Marianne, K. , SUDBECK, Elise , WRIGHT, Jonathan
发明人： ALBERS, Ronald, J. , AYALA, Leticia , CLAREEN, Steven, S. , DELGADO MEDEROS, Maria, Mercedes , HILGRAF, Robert , HEGDE, Sayee, G. , HUGHES, Kevin , KOIS, Adam , PLANTEVIN-KRENITSKY, Veronique , MCCARRICK, Meg , NADOLNY, Lisa , PALANKI, Moorthy, S.S. , SAHASRAMUDHE, Kiran , SAPIENZA, John , SATOH, Yoshitaka , SLOSS, Marianne, K. , SUDBECK, Elise , WRIGHT, Jonathan
IPC分类号： A61K31/52 , A61P3/10
CPC分类号： A61K31/52 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structure (I), wherein R 1 , R 2 and R 3 are as defined herein, compositions comprising an effective amount of an Aminopurine. Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
摘要翻译：本文提供具有以下结构（I）的氨基嘌呤化合物，其中R 1，R 2和R 3如本文所定义，组合物包含有效量的氨基嘌呤。治疗或预防癌症，心血管疾病，肾脏疾病，自身免疫性疾病，炎性病症，黄斑变性，缺血再灌注损伤，疼痛及相关综合征，疾病相关性消瘦，石棉相关病症，肺部疾病高血压或通过抑制JNK途径可治疗或可预防的病症包括向有需要的患者施用有效量的氨基嘌呤化合物。

2. 发明申请

WO2006076595A1 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 审中-公开
标题翻译：羟基取代的氨基酸，其组合物及其处理方法
公开(公告)号：WO2006076595A1
公开(公告)日：2006-07-20
申请号：PCT/US2006/001275
申请日：2006-01-13
申请人： SIGNAL PHARMACEUTICALS, LLC , ALBERS, Ronald , AYALA, Leticia , CLAREEN, Steven, S. , DELGADO MEDEROS, Maria, M. , HILGRAF, Robert , HEDGE, Sayee , HUGHES, Kevin , KOIS, Adam , PLANTEVIN-KRENITSKY, Veronique , MCCARRICK, Meg , NADOLNY, Lisa , PALANKI, Moorthy , SAHASRABUDHE, Kiran , SAPIENZA, John , SATOH, Yoshitaka , SLOSS, Marian , SUDBECK, Elise , WRIGHT, Jonathan
发明人： ALBERS, Ronald , AYALA, Leticia , CLAREEN, Steven, S. , DELGADO MEDEROS, Maria, M. , HILGRAF, Robert , HEDGE, Sayee , HUGHES, Kevin , KOIS, Adam , PLANTEVIN-KRENITSKY, Veronique , MCCARRICK, Meg , NADOLNY, Lisa , PALANKI, Moorthy , SAHASRABUDHE, Kiran , SAPIENZA, John , SATOH, Yoshitaka , SLOSS, Marian , SUDBECK, Elise , WRIGHT, Jonathan
IPC分类号： C07D473/00 , C07D473/32 , A61K31/52 , A61P3/00 , A61P9/00
CPC分类号： C07D473/00 , A61K31/52 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structure: (I) wherein R 1 , R 2 and and R 3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
摘要翻译：本文提供了具有以下结构的氨基嘌呤化合物：其中R 1，R 2和R 3如本文所定义的（I），组合物包括有效量的氨基嘌呤化合物和治疗或预防癌症，心血管疾病，肾脏疾病，自身免疫病症，炎性病症，黄斑变性，缺血再灌注损伤，疼痛及相关综合征，疾病相关性消瘦，石棉相关病症，肺动脉高压或通过抑制JNK途径可治疗或可预防的病症，包括向有需要的患者施用有效量的氨基嘌呤化合物。

4. 发明授权

EP1838710B1 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 有权转让
标题翻译：卤代芳基取代氨基嘌呤，THEREOF组合物和治疗方法，这些方法
公开(公告)号：EP1838710B1
公开(公告)日：2009-07-01
申请号：EP06718361.6
申请日：2006-01-13
申请人： Signal Pharmaceuticals LLC , Pharmacopeia, LLC
发明人： ALBERS, Ronald , AYALA, Leticia , CLAREEN, Steven, S. , DELGADO MEDEROS, Maria, M. , HILGRAF, Robert , HEDGE, Sayee , HUGHES, Kevin , KOIS, Adam , PLANTEVIN-KRENITSKY, Veronique , MCCARRICK, Meg , NADOLNY, Lisa , PALANKI, Moorthy , SAHASRABUDHE, Kiran , SAPIENZA, John , SATOH, Yoshitaka , SLOSS, Marian , SUDBECK, Elise , WRIGHT, Jonathan , COLE, Andrew G. , HENDERSON, Ian
IPC分类号： C07D473/00 , C07D473/32 , A61K31/52 , A61P3/00 , A61P9/00
CPC分类号： C07D473/00 , A61K31/52 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structure: (I) wherein R1 , R2 and and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

5. 发明公开

EP2010186A1 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 失效
标题翻译：卤代取代的氨基酸，其组合物及其治疗方法
公开(公告)号：EP2010186A1
公开(公告)日：2009-01-07
申请号：EP07756113.2
申请日：2007-04-25
申请人： Signal Pharmaceuticals LLC
发明人： ALBERS, Ronald, J. , AYALA, Leticia , CLAREEN, Steven, S. , DELGADO MEDEROS, Maria, Mercedes , HILGRAF, Robert , HEGDE, Sayee, G. , HUGHES, Kevin , KOIS, Adam , PLANTEVIN-KRENITSKY, Veronique , MCCARRICK, Meg , NADOLNY, Lisa , PALANKI,Moorthy, S.S. , SAHASRAMUDHE, Kiran , SAPIENZA, John , SATOH, Yoshitaka , SLOSS, Marianne, K. , SUDBECK, Elise , WRIGHT, Jonathan
IPC分类号： A61K31/52 , A61P3/10
CPC分类号： A61K31/52 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structure (I), wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine. Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
摘要翻译：本文提供具有以下结构（I）的氨嘌呤化合物，其中R 1，R 2和R 3如本文所定义，包含有效量的氨基嘌呤的组合物。用于治疗或预防癌症，心血管疾病，肾脏疾病，自身免疫病症，炎性病症，黄斑变性，缺血 - 再灌注损伤，疼痛和相关综合征，疾病相关性消耗，石棉相关病症，肺部疾病高血压或通过抑制JNK途径可治疗或可预防的病症，所述方法包括向有需要的患者施用有效量的氨嘌呤化合物。

6. 发明申请

WO2008070320A2 METHOD AND SYSTEM FOR PROVIDING A WIDGET FOR DISPLAYING MULTIMEDIA CONTENT 审中-公开
标题翻译：用于提供显示多媒体内容的小部件的方法和系统
公开(公告)号：WO2008070320A2
公开(公告)日：2008-06-12
申请号：PCT/US2007/082293
申请日：2007-10-23
申请人： CHIPIN INC. , WILLIAMS, Carnet , LAGON, Olin , HUGHES, Kevin
发明人： WILLIAMS, Carnet , LAGON, Olin , HUGHES, Kevin
IPC分类号： G06F3/14
CPC分类号： G06Q30/02 , G06Q10/107 , G06Q30/06
摘要： A system and computer implemented method for providing a widget for dynamically displaying multimedia content are described. The method and system include receiving a plurality of parameters for an ancestor widget of the widget. The ancestor widget is embeddable, copyable, and for dynamically displaying at least a portion of the multimedia content. The widget being a copy of the ancestor widget. The plurality of parameters relate to controlling modification of the widget. The method and system also include rendering the widget based on the plurality of parameters. In another aspect, the method and system include providing embeddable code based on a plurality of parameters for the ancestor widget of the widget. In this aspect, the widget is also rendered the widget based on the plurality of parameters.
摘要翻译：描述了用于提供用于动态显示多媒体内容的小部件的系统和计算机实现的方法。该方法和系统包括接收小部件的祖先小部件的多个参数。祖先小部件是可嵌入的，可复制的，并且用于动态显示至少一部分多媒体内容。该小部件是祖先小部件的副本。多个参数涉及控制微件的修改。该方法和系统还包括基于多个参数来呈现小部件。在另一方面，该方法和系统包括基于用于小部件的祖先小部件的多个参数来提供可嵌入代码。在这方面，小部件也基于多个参数呈现小部件。

7. 发明申请

WO2010014786A1 METHOD AND SYSTEM FOR MIXING OF MULTIMEDIA CONTENT 审中-公开
标题翻译：多媒体内容混合的方法和系统
公开(公告)号：WO2010014786A1
公开(公告)日：2010-02-04
申请号：PCT/US2009/052213
申请日：2009-07-30
申请人： CHIPIN INC. , WILLIAMS, Carnet , HUGHES, Kevin , MCNEELY, Matthew
发明人： WILLIAMS, Carnet , HUGHES, Kevin , MCNEELY, Matthew
IPC分类号： G06F17/00
CPC分类号： G06F17/30017 , G06F17/3089
摘要： Computer-implemented methods and systems for providing a copy of a widget for a user are described. The widget is copyable, for dynamically displaying multimedia content, has a widget owner, corresponds to embeddable code, and is viewable on a site by the user. The method and system include receiving from the user a request for mixing the widget to provide the copy. The copy is a customized copy of the widget. The method and system also include receiving at least one change to the widget as viewed by the user and storing the at least one change in a memory and separate from the embeddable code. The customized copy is renderable based on the embeddable code and the at least one change.
摘要翻译：描述了用于为用户提供小部件的副本的计算机实现的方法和系统。小部件是可复制的，用于动态显示多媒体内容，具有小部件所有者，对应于可嵌入代码，并且可由用户在站点上查看。该方法和系统包括从用户接收用于混合小部件以提供副本的请求。该副本是窗口小部件的自定义副本。所述方法和系统还包括：在由用户观察时接收对窗口小部件的至少一个改变，并且将所述至少一个改变存储在存储器中并与可嵌入代码分离。基于可嵌入代码和至少一个更改，可自定义副本可呈现。

8. 发明申请

WO2009099403A2 METHOD AND SYSTEM FOR PROVIDING A WIDGET FOR DISPLAYING MULTIMEDIA CONTENT 审中-公开
标题翻译：提供用于显示多媒体内容的宽带的方法和系统
公开(公告)号：WO2009099403A2
公开(公告)日：2009-08-13
申请号：PCT/US2007/082297
申请日：2007-10-23
申请人： CHIPIN INC. , WILLIAMS, Carnet , LAGON, Olin , HUGHES, Kevin
发明人： WILLIAMS, Carnet , LAGON, Olin , HUGHES, Kevin
IPC分类号： H04L9/32 , H04L9/00
CPC分类号： G06Q30/02 , G06Q10/107 , G06Q30/06
摘要： A system and computer implemented method for providing a widget are described. The method and system include receiving a rule and at least one condition corresponding to the rule for the widget. The widget is embeddable and dynamically displays multimedia content. The widget provides input to a provider and receives at least a portion of updatable multimedia content from the provider. The rule indicates at least one action in response to the at least one condition. The method and system further include performing the at least one action for the widget based on the rule and in response to the at least one condition.
摘要翻译：描述了一种用于提供小窗口的系统和计算机实现的方法。所述方法和系统包括接收规则和与所述小部件的规则相对应的至少一个条件。该小部件是可嵌入的并动态显示多媒体内容。小部件向提供者提供输入，并从提供者接收至少一部分可更新的多媒体内容。该规则指示响应于至少一个条件的至少一个动作。该方法和系统还包括基于该规则并响应于该至少一个条件来执行该小部件的该至少一个动作。

9. 发明申请

WO2011161404A1 WOOD PRESERVATIVE COMPOSITIONS USEFUL FOR TREATING COPPER-TOLERANT FUNGI 审中-公开
标题翻译：用于治疗耐受性真菌的木材防腐剂组合物
公开(公告)号：WO2011161404A1
公开(公告)日：2011-12-29
申请号：PCT/GB2011/000930
申请日：2011-06-21
申请人： ARCH TIMBER PROTECTION LIMITED , MARS, Craig, Andrew , CANTRELL, David, Grindon , HUGHES, Kevin , HUGHES, Andrew, Stewart
发明人： MARS, Craig, Andrew , CANTRELL, David, Grindon , HUGHES, Kevin , HUGHES, Andrew, Stewart
IPC分类号： A01N33/12 , A01N43/653 , B27K3/52 , A01P3/00 , A01N59/20
CPC分类号： A01N33/12 , A01N43/653 , B27K3/002 , B27K3/20 , B27K3/343 , Y10T428/31971 , Y10T428/31982 , Y10T428/31986 , Y10T428/31989 , Y10T428/31993 , Y10T428/662 , A01N59/20 , A01N2300/00
摘要： The present invention provides a method of protecting wood or other celiulosic material from decay by copper-tolerant fungi, and wood preservative formulations for use in the same. The wood preservative formulations comprise a biocidal metal compound, a 1,2,4-triazole and a didecyl quaternary ammonium cation. Didecyldimethyl quaternary ammonium compounds are particularly preferred.
摘要翻译：本发明提供了一种保护木材或其他纤维素材料免受铜耐受性真菌腐烂的方法，以及用于其中的木材防腐剂制剂。木材防腐剂配方包括杀生物金属化合物，1,2,4-三唑和二癸基季铵阳离子。十二烷基二甲基季铵化合物是特别优选的。

10. 发明申请

WO2008052013A2 METHOD AND SYSTEM FOR PROVIDING A WIDGET USABLE IN AFFILIATE MARKETING 审中-公开
标题翻译：提供可用于关联营销的宽带的方法和系统
公开(公告)号：WO2008052013A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/082303
申请日：2007-10-23
申请人： CHIPIN INC. , WILLIAMS, Carnet , LAGON, Olin , HUGHES, Kevin
发明人： WILLIAMS, Carnet , LAGON, Olin , HUGHES, Kevin
IPC分类号： G06F3/14
CPC分类号： G06Q30/02 , G06Q10/107 , G06Q30/06
摘要： A system and computer implemented method for providing a widget are described. The method and system include rendering the widget on a site. The widget dynamically displays multimedia content associated with a campaign. The widget is also embeddable, copyable, and allows for at least one user action. The method and system also include receiving at least one input related to the at least one action and updating the widget based on a goal corresponding to the at least one action.
摘要翻译：描述了一种用于提供小窗口的系统和计算机实现的方法。该方法和系统包括将窗口小部件呈现在站点上。小部件动态显示与广告系列相关联的多媒体内容。小部件也可嵌入，可复制，并允许至少一个用户操作。所述方法和系统还包括接收与所述至少一个动作相关的至少一个输入，并基于与所述至少一个动作相对应的目标来更新所述小部件。

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