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1. 发明专利

JPS6064908A COSMETIC 失效
公开(公告)号：JPS6064908A
公开(公告)日：1985-04-13
申请号：JP17339783
申请日：1983-09-20
申请人： SHISEIDO CO LTD
发明人： TSUTSUMI KENJI , EDA TAKASHI , YOKOI TOKIYA
IPC分类号： A61K8/30 , A61K8/42 , A61K8/67 , A61K8/96 , A61K8/98 , A61Q19/00 , C12N9/99
摘要： PURPOSE:To provide a cosmetic having excellent effect to beautify the skin, by using an aqueous extract of the liver or spleen of mammals, in combination with vitamin c, vitamin B6, pantothenic acid, or their salt. CONSTITUTION:The objective cosmetic contains (A) 0.001-2wt% (in terms of dried residue) aqueous extract of the liver or spleen of mammals and (B) 0.01- 2wt% one or more substances selected from vitamin C, vitamin B6, pantothenic acid, and their salts. The component A can be produced by pulverizing the frozen spleen of cattle, extracting with hot water of >=60 deg.C for >=1hr, heating at >=80 deg.C for >=10min, filtering and concentrating the heat-treated product, adding ethanol to the concentrate, filtering again to remove the proteins, and clarifying the product.

2. 发明专利

JPS6064909A COSMETIC 失效
公开(公告)号：JPS6064909A
公开(公告)日：1985-04-13
申请号：JP17339883
申请日：1983-09-20
申请人： SHISEIDO CO LTD
发明人： TSUTSUMI KENJI , EDA TAKASHI , YOKOI TOKIYA
IPC分类号： A61K8/96 , A61K8/18 , A61K8/73 , A61K8/98 , A61K35/26 , A61K35/28 , A61K35/36 , A61K35/407 , A61P17/00 , A61Q19/00
摘要： PURPOSE:To provide a cosmetic having excellent effect to cure the wound, and containing an aqueous extract of the liver or spleen of mammals and a skin extract. CONSTITUTION:The objective cosmetic having synergistically improved wound- curing effect can be produced by compounding (A) an aqueous extract of the liver or spleen of mammals such as cattle, pig, etc. and (B) a skin extract such as mucopolysaccharide (e.g. hyaluronic acid, dermatan sulfate, chondroitinsulfuric acid, or their salts), collagen, elastin, etc. to a skin cosmetic such as beauty lotion, cream, milky lotion, pack, etc. The amount of the components A and B are generally 0.001-2wt% (in terms of dried residue) and 0.005-2wt% (in terms of solid component), based on the whole cosmetic composition. Since the excellent wound-curing effect can be maintained even by adding a component having suppressing effect against the curing of wound to the above cosmetic, the components used generally in cosmetics can be added to the above cosmetic in addition to the above components, according to the use.

3. 发明专利

JPS61238712A SKIN COSMETIC 失效
公开(公告)号：JPS61238712A
公开(公告)日：1986-10-24
申请号：JP8206485
申请日：1985-04-17
申请人： SHISEIDO CO LTD
发明人： TSUTSUMI KENJI , OKUDA TAKAYA , KITA SEIICHI , UZUKA MAKOTO
IPC分类号： A61K8/72 , A61K8/64 , A61K8/73 , A61K8/96 , A61Q19/00
摘要： PURPOSE:A skin cosmetic, obtained by incorporating a cosmetic containing a cell adhesion promoting substance with a specific amount of mucopolysacharide, capable of suppressing the deposition of the cell adhesion promoting substance at low temperatures and having improved stability and usability. CONSTITUTION:A skin cosmetic, obtained by incorporating a cosmetic containing a cell adhesion promoting substance, e.g. fibronectin, laminin or chondronectin, in the living body with a mucopolysaccharide having skin activating action, e.g. neutral polysaccharide in glucosamine and acidic mucopolysaccharide such as hyaluronic acid, in an amount of 0.001-5.0wt%, preferably 0.05-5wt%, and capable of preventing the deposition of the cell adhesion promoting substance without losing the product characteristics as the cosmetic by incorporating a large amount of a humectant, etc. therewith, and having improved stability. The amount of the above-mentioned cell adhesion promotion substance to be incorporated is generally 0.0001-1.0wt%.

4. 发明专利

JPS61167612A COSMETIC 失效
公开(公告)号：JPS61167612A
公开(公告)日：1986-07-29
申请号：JP976785
申请日：1985-01-22
申请人： SHISEIDO CO LTD
发明人： EDA TAKASHI , TSUTSUMI KENJI
IPC分类号： A61K8/96 , A61K8/92 , A61Q1/00 , A61Q1/12 , A61Q5/00 , A61Q19/00
摘要： PURPOSE:To provide a cosmetic having excellent usability, safety and stability, by compounding an oil obtained from pili nut. CONSTITUTION:A cosmetic such as facial cosmetic, make-up cosmetic, hair cosmetic, aromatic cosmetic, body cosmetic, etc., is compounded with >=1wt% (based on whole cosmetic) oil (pili nut oil) obtained from pili nut. The obtained cosmetic exhi-bits unprecedent unique feeling. Since pili nut oil has a melting point of about 30 deg.C, the cosmetic is melted by the body heat and gives desirable spreadability especially when pili nut oil is compounded to lipstick, etc. The stability of pili nut oil can be improved by using an antioxidant such as vitamin E, BHA, BHT, anthracin, etc., in combination with pili nut oil.

5. 发明专利

JPS5976007A Cosmetic 失效
标题翻译：化妆品
公开(公告)号：JPS5976007A
公开(公告)日：1984-04-28
申请号：JP18573882
申请日：1982-10-22
申请人： Shiseido Co Ltd
发明人： TSUTSUMI KENJI , EDA TAKASHI , OKUDA TAKAYA
IPC分类号： A61K8/00 , A61K8/64 , A61K8/72 , A61K8/96 , A61Q5/00 , A61Q7/00 , A61Q19/00 , A61Q19/02
CPC分类号： A61Q19/00 , A61K8/64 , A61Q5/00 , A61Q19/04
摘要： PURPOSE:A cosmetic, containing fibronectin which is one of glycoproteins and having activating, moistening and beautifying and whitening action on the skin and hair tonic and nourishing action the hair. CONSTITUTION:A cosmetic containing 0.00001-0.1wt% fibronectin (another name: cold-insoluble globulin). The fibronectin is present in human or animal cells or blood plasmas, and a 5-10% fibronectin solution is obtained by treating cultivated cells with 0.2M urea, and the fibronectin is extracted by subjecting the cultivated cells to the affinity chromatography with a gelatin-modified adsorbent. The above-mentioned cosmetic may contain an oily substance, surfactant, pigment, perfume, preservative, humectant, ultraviolet light absorber and others, if necessary within such a range as not to deteriorate the effect thereof.
摘要翻译：目的：一种化妆品，含有纤维连接蛋白，是糖蛋白之一，具有活化，润泽美化和美白作用，对皮肤和头发滋养，滋润头发。构成：含有0.00001-0.1wt％纤连蛋白（另名：冷不溶性球蛋白）的化妆品。纤维连接蛋白存在于人或动物细胞或血浆中，通过用0.2M尿素处理培养的细胞获得5-10％的纤连蛋白溶液，并通过将培养的细胞进行亲和层析，改性吸附剂。如果需要，上述化妆品可以含有油性物质，表面活性剂，颜料，香料，防腐剂，保湿剂，紫外线吸收剂等，不会降低其效果。

6. 发明专利

JPH0412243B2 失效
公开(公告)号：JPH0412243B2
公开(公告)日：1992-03-04
申请号：JP17339883
申请日：1983-09-20
申请人： SHISEIDO CO LTD
发明人： TSUTSUMI KENJI , EDA TAKASHI , YOKOI TOKYA
IPC分类号： A61K8/96 , A61K8/18 , A61K8/73 , A61K8/98 , A61K35/26 , A61K35/28 , A61K35/36 , A61K35/407 , A61P17/00 , A61Q19/00

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