专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

MEP60708A NOVEL THIOPHENYLGLYCOSIDE DERIVATIVES, METHODS FOR PRODUCTION THEREOF, MEDICAMENTS COMPRISING SAID COMPOUNDS AND USE THEREOF 未知
公开(公告)号：MEP60708A
公开(公告)日：2011-05-10
申请号：MEP60708
申请日：2003-06-27
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： GLOMBIK HEINER , FRICK WENDELIN , HEUER HUBERT , KRAMER WERNER , BRUMMERHOP HARM , PLETTENBURG OLIVER
IPC分类号： C07H7/00 , A61K31/7042 , A61K31/7048 , A61P3/04 , A61P3/10 , A61P7/00 , A61P7/02 , A61P9/08 , A61P9/10 , A61P11/06 , A61P13/12 , A61P17/06 , A61P19/10 , A61P25/00 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/00 , A61P31/18 , A61P35/00 , A61P37/02 , C07H17/00
摘要： Thienyl-glycoside compounds (I) are new. Thienyl-glycoside compounds of formula (I) and their salts are new. [Image] R 1, R 2H, halo, OH, NO 2, CN, COOH, COT', COOT', CONH 2, CONHT', CONT' 2, T', 2-6C alkenyl, 2-6C alkynyl, OT', -T'-OH, -T'-OT', Ph,CH 2Ph, (1-4C) alkylcarbonyl (optionally substituted (os) by one or more F), SO 2NH 2, SO 2NHT, SO 2NT 2, ST, S(CH 2) pPh', SOT, SO(CH 2) pPh', SO 2T, SO 2(CH 2) pPh', NH 2, NHT, NT 2, 1-7C acylamino, Ph'' or -O(CH 2) pPh''; T : 1-6C alkyl; T' : 1-6C alkyl (os by one or more F); p : 0-6; Ph' : phenyl (os by 1 or 2 of F, Cl, Br, OH, CF 3, NO 2, CN, OCF 3, OT, T or NH 2); Ph'' : phenyl (os by 1-3 of halo, OH, CF 3, NO 2, CN, OCF 3, OT, T, NH 2, NHT, NT 2, SO 2Me, COOH, COOT or CONH 2); A : direct bond or 1-15C alkanediyl (optionally having one or more C-atom(s) replaced by O, CO, CH=CH, CC, S, CH(OH), CHF, SO, SO 2, N(T), N(-T-Ph) or NH); n : 0-4; Cyc 1>3-7 membered saturated, partially unsaturated or unsaturated ring, optionally having one C-atom replaced by O or S; R 3 - R 5H, halo, OH, NO 2, CN, COOH, COOT', (1-4C) alkylcarbonyl (os by one or more F), CONH 2, CONHT', CONT' 2, T', 2-6C alkenyl, 2-6C alkynyl, 1-12C alkoxy (os by one or more F), -T'-OH, -T'-OT', Ph,CH 2Ph, SO 2NH 2, SO 2NHT, SO 2NT 2, ST, S(CH 2) pPh', SOT, SO(CH 2) pPh', SO 2T, SO 2(CH 2) pPh', NH 2, NHT, NT 2, 1-7C acylamino, Ph'', -(CH 2) pPh'' or -O(CH 2) pPh''; or R 3 + R 4group completing a 5-7 membered saturated, partially unsaturated or unsaturated ring (Cyc 2>), optionally having 1 or 2 C-atom(s) replaced by N, O or S and os by T, 2-5C alkenyl or 2-5C (all optionally having one CH 2 replaced by O) or by F, Cl, OH, CF 3, NO 2, CN, (1-4C) alkoxycarbonyl, CONH 2, (1-4C) alkylaminocarbonyl or OCF 3; and provided that when R 3 and R 4 form a ring, R 5 is H. ACTIVITY : Antidiabetic; nephrotropic; ophthalmological; neuroprotective; anorectic; cardiant; vasotropic; thrombolytic; anticoagulant; antiarteriosclerotic; antiinflammatory; immunosuppressive; anti-HIV; antiasthmatic; osteopathic; cytostatic; antipsoriatic; nootropic; neuroleptic; antibacterial. MECHANISM OF ACTION : Glucose transport regulator. In a glucose transport assay in rabbit renal cortex 'Burstensaum' membrane vesicles, 2-hydroxymethyl-6-(2-(2-(4-chlorophenyl)-ethyl)-thien-3-yloxy)-tetrahydropyran-3,4,5-triol (Ia) (in beta -D-gluco form) had IC 2 5 0.9 MicroM.

2. 发明专利

ES2358371T3 NUEVOS DERIVADOS DE 1,4-BENZOTIEPINA-1,1-DIOXIDO SUSTITUIDOS CON RADICALES BENCILO, PROCEDIMIENTO PARA SU PREPARACION, MEDICAMENTOS QUE CONTIENEN ESTOS COMPUESTOS Y SU USO. 未知
公开(公告)号：ES2358371T3
公开(公告)日：2011-05-10
申请号：ES07819434
申请日：2007-10-30
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： FRICK WENDELIN , GLOMBIK HEINER , THEIS STEFAN , HEUER HUBERT , SCHAEFER HANS-LUDWIG , KRAMER WERNER
IPC分类号： C07H5/06 , A61K31/7028
摘要： Compuestos de la fórmula **Fórmula** o así como sus sales farmacéuticamente aceptables.

4. 发明专利

RS51146B NOVI DIFENIL-AZETIDINON SA POBOLJŠANIM FIZIOLOŠKIM OSOBINAMA POSTUPAK ZA NJEGOVU PROIZVODNJU,LEKOVI KOJI SADRŽE OVO JEDINJENJE I NJIHOVA UPOTREBA 未知
公开(公告)号：RS51146B
公开(公告)日：2010-10-31
申请号：YUP20050719
申请日：2004-03-16
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： LINDENSCHMIDT ANDREAS , JAEHNE GERHARD , FRICK WENDELIN , GLOMBIK HEINER , KRAMER WERNER , HEUER HUBERT , FLOHR STEFANIE , SCHAEFER HANS-LUDWIG , GALIA ERIC
IPC分类号： A61K31/397 , C07D205/08 , A61P3/06 , C07C233/18
摘要： Jedinjenje formule I,kao i njegove farmaceutski prihvatljive soli.Prijava sadrži još 13 patentnih zahteva.

6. 发明专利

AT478842T 未知
公开(公告)号：AT478842T
公开(公告)日：2010-09-15
申请号：AT03760591
申请日：2003-06-04
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： JAEHNE GERHARD , FRICK WENDELIN , FLOHR STEFANIE , LINDENSCHMIDT ANDREAS , GLOMBIK HEINER , KRAMER WERNER , HEUER HUBERT , SCHAEFER HANS-LUDWIG
IPC分类号： C07D205/08 , A61K31/137 , A61K31/195 , A61K31/397 , A61K31/426 , A61K31/48 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/64 , A61K38/27 , A61K38/28 , A61K45/00 , A61K45/06 , A61P3/06 , A61P5/50 , A61P9/10 , C07D403/12 , C07D453/02 , C07D471/08 , C07D487/08

8. 发明专利

AU2003289911B2 Novel fluoroglycoside heterocyclic derivatives, pharmaceutical products containing said compounds and the use thereof 未知
公开(公告)号：AU2003289911B2
公开(公告)日：2009-09-17
申请号：AU2003289911
申请日：2003-11-28
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： KRAMER WERNER , HEUER HUBERT , FRICK WENDELIN , GLOMBIK HEINER , PLETTENBURG OLIVER , BRUMMERHOP HARM
IPC分类号： C07H17/00 , A61K31/70 , A61K31/7048 , A61K31/7052 , A61K31/7056 , A61P3/10 , C07H15/203 , C07H17/02 , C07H19/056
摘要： Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof The invention relates to substituted heterocyclic fluoroglycoside derivatives of the formula I in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation. The compounds are suitable for example as antidiabetics.

9. 发明专利

PL1862455T3 Kwas 11-((4R,6R)-4,5,6-trihydroksy-3-(R)-hydroksy-2-(S)-hydroksy-heksylokarbamoilo)-undekanowy 未知
公开(公告)号：PL1862455T3
公开(公告)日：2009-07-31
申请号：PL07016889
申请日：2004-03-16
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： JAEHNE GERHARD , FRICK WENDELIN , LINDENSCHMIDT ANDREAS , FLOHR STEFANIE , HEUER HUBERT , SCHAEFER HANS-LUDWIG , KRAMER WERNER , GALIA ERIC , GLOMBIK HEINER
IPC分类号： A61K31/397 , C07D205/08 , A61P3/06 , C07C233/18 , C07C235/74

10. 发明专利

NO20091746L 未知
公开(公告)号：NO20091746L
公开(公告)日：2009-07-21
申请号：NO20091746
申请日：2009-05-04
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： FRICK WENDELIN , HEUER HUBERT , SCHAEFER HANS-LUDWIG , LINDENSCHMIDT ANDREAS , JAEHNE GERHARD , KRAMER WERNER , GRAF CLAUS-DIETER , SCHMIDER WOLFGANG
IPC分类号： C07D205/08
摘要： The invention therefore relates to the compound of the formula I or a pharmaceutically acceptable salt thereof, its pharmaceutically composition and uses.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式