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1. 发明授权

US09889043B2 System and apparatus for delivering a laser beam to the lens of an eye 有权
公开(公告)号：US09889043B2
公开(公告)日：2018-02-13
申请号：US12217295
申请日：2008-07-02
申请人： Rudolph W. Frey , Gary P. Gray , Neil Zepkin , George R. Downes, Jr. , Jorge A. De Castro , Jerome R. Kuszak , Richard Ty Olmstead
发明人： Rudolph W. Frey , Gary P. Gray , Neil Zepkin , George R. Downes, Jr. , Jorge A. De Castro , Jerome R. Kuszak , Richard Ty Olmstead
IPC分类号： A61F9/007 , A61F9/008 , A61F9/01 , A61B18/20 , A61B90/00
CPC分类号： A61F9/008 , A61B2018/20351 , A61B2018/204 , A61B2090/061 , A61F9/00825 , A61F9/00827 , A61F9/00838 , A61F2009/00842 , A61F2009/00844 , A61F2009/0087 , A61F2009/00897
摘要： A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a range determining system for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.

2. 发明授权

US09180051B2 System and apparatus for treating the lens of an eye 有权
标题翻译：用于治疗眼睛晶状体的系统和装置
公开(公告)号：US09180051B2
公开(公告)日：2015-11-10
申请号：US11414819
申请日：2006-05-01
申请人： Rudolph W. Frey , Gary P. Gray , Dennis R. Pape , George R. Downes, Jr. , Jorge A. De Castro , Jerome R. Kuszak
发明人： Rudolph W. Frey , Gary P. Gray , Dennis R. Pape , George R. Downes, Jr. , Jorge A. De Castro , Jerome R. Kuszak
IPC分类号： A61B18/20 , A61F9/008 , A61B19/00 , A61F9/007
CPC分类号： A61F9/00834 , A61B90/30 , A61B90/361 , A61B2018/20351 , A61F9/00736 , A61F9/008 , A61F2009/0087 , A61F2009/00887 , A61F2009/00897
摘要： A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided apparatus for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.
摘要翻译：提供了一种用于增加调节幅度和/或改变折射力的系统和装置和/或能够去除天然晶状体的透明或白内障透镜材料。通常，该系统包括激光器，用于传送激光束的光学器件和用于以特定图案将激光束传送到透镜的控制系统。还提供了用于确定透镜相对于激光器的形状和位置的装置。还提供了一种用于以预定的射击图案将眼睛的透镜中的激光束传送的方法和系统。

3. 发明申请

US20100004641A1 System and apparatus for delivering a laser beam to the lens of an eye 有权
标题翻译：用于将激光束传送到眼睛的透镜的系统和装置
公开(公告)号：US20100004641A1
公开(公告)日：2010-01-07
申请号：US12217295
申请日：2008-07-02
申请人： Rudolph W. Frey , Gary P. Gray , Neil Zepkin , George R. Downes, JR. , Jorge A. De Castro , Jerome R. Kuszak , Richard Ty Olmstead
发明人： Rudolph W. Frey , Gary P. Gray , Neil Zepkin , George R. Downes, JR. , Jorge A. De Castro , Jerome R. Kuszak , Richard Ty Olmstead
IPC分类号： A61F9/008 , A61B18/20
CPC分类号： A61F9/008 , A61B2018/20351 , A61B2018/204 , A61B2090/061 , A61F9/00825 , A61F9/00827 , A61F9/00838 , A61F2009/00842 , A61F2009/00844 , A61F2009/0087 , A61F2009/00897
摘要： A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a range determining system for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.
摘要翻译：提供了一种用于增加调节幅度和/或改变折射力的系统和装置和/或能够去除天然晶状体的透明或白内障透镜材料。通常，该系统包括激光器，用于传送激光束的光学器件和用于以特定图案将激光束传送到透镜的控制系统。还提供了一种用于确定透镜相对于激光器的形状和位置的范围确定系统。还提供了一种用于以预定的射击图案将眼睛的透镜中的激光束传送的方法和系统。

4. 发明授权

US5442412A Patient responsive eye fixation target method and system 失效
标题翻译：患者反应眼固定目标的方法和系统
公开(公告)号：US5442412A
公开(公告)日：1995-08-15
申请号：US232959
申请日：1994-04-25
申请人： Rudolph W. Frey , George R. Downes, Jr.
发明人： Rudolph W. Frey , George R. Downes, Jr.
IPC分类号： A61B3/113 , A61B5/00 , A61B3/02
CPC分类号： A61B5/486 , A61B3/113
摘要： A biofeedback method and system provide eye position feedback to a patient. A first light source produces a ring of visible light centered about an optical axis at a perceived first position. A second light source produces a dot of visible light centered on the same optical axis as that of the ring at a perceived second position. As perceived by the eye, the ring's first position is closer to the eye than the dot's second position. The eye will further perceive the dot as being centered in the ring when the eye moves its visual axis into spatial and angular alignment with the optical axis shared by the dot and ring. An eye movement sensor detects a quantifiable amount of eye movement to generate an error signal. The error signal is supplied to the second light source to adjust the dot's appearance whenever the patient needs to realign the eye's visual axis with the optical axis of the dot and the ring. The invention may also include a third light source to produce a directing light at a visually resolvable angle from the dot in a direction that is approximately opposite to the direction of eye movement.
摘要翻译：生物反馈方法和系统向患者提供眼睛位置反馈。第一光源在感知的第一位置处产生围绕光轴居中的可见光环。在感知的第二位置处，第二光源产生以与环的相同的光轴为中心的可见光点。正如眼睛所察觉到的，戒指的第一个位置比点的第二个位置更接近眼睛。当眼睛将其视轴移动到由点和圈共享的光轴的空间和角度对准时，眼睛将进一步感觉到该点以环为中心。眼睛运动传感器检测可量化的眼睛运动量以产生误差信号。每当患者需要用点和环的光轴重新对准眼睛的视轴时，将误差信号提供给第二光源以调整点的外观。本发明还可以包括第三光源，以在与眼睛运动方向大致相反的方向上以点的视觉上可分辨的角度产生引导光。

5. 发明申请

US20140066906A9 System and apparatus for delivering a laser beam to the lens of an eye 有权
标题翻译：用于将激光束传送到眼睛的透镜的系统和装置
公开(公告)号：US20140066906A9
公开(公告)日：2014-03-06
申请号：US12217295
申请日：2008-07-02
申请人： Rudolph W. Frey , Gary P. Gray , Neil Zepkin , George R. Downes, JR. , Jorge A. De Castro , Jerome R. Kuszak , Richard Ty Olmstead
发明人： Rudolph W. Frey , Gary P. Gray , Neil Zepkin , George R. Downes, JR. , Jorge A. De Castro , Jerome R. Kuszak , Richard Ty Olmstead
IPC分类号： A61F9/008 , A61B18/20
CPC分类号： A61F9/008 , A61B2018/20351 , A61B2018/204 , A61B2090/061 , A61F9/00825 , A61F9/00827 , A61F9/00838 , A61F2009/00842 , A61F2009/00844 , A61F2009/0087 , A61F2009/00897
摘要： A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a range determining system for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.
摘要翻译：提供了一种用于增加调节幅度和/或改变折射力的系统和装置和/或能够去除天然晶状体的透明或白内障透镜材料。通常，该系统包括激光器，用于传送激光束的光学器件和用于以特定图案将激光束传送到透镜的控制系统。还提供了一种用于确定透镜相对于激光器的形状和位置的范围确定系统。还提供了一种用于以预定的射击图案将眼睛的透镜中的激光束传送的方法和系统。

6. 发明授权

US5632742A Eye movement sensing method and system 失效
标题翻译：眼动检测方法及系统
公开(公告)号：US5632742A
公开(公告)日：1997-05-27
申请号：US232990
申请日：1994-04-25
申请人： Rudolph W. Frey , John E. McWhirter , Neil Zepkin , George R. Downes, Jr.
发明人： Rudolph W. Frey , John E. McWhirter , Neil Zepkin , George R. Downes, Jr.
IPC分类号： A61B3/113 , A61F9/007 , A61N5/06
CPC分类号： A61B3/113
摘要： A method and system are provided for sensing eye movement, such as saccadic eye movement, in a non-intrusive fashion. An optical delivery arrangement converts a laser beam pulse into a plurality of light spots. The light spots are focused such that they are incident on a corresponding plurality of positions located on a boundary whose movement is coincident with that of eye movement. The boundary can be defined by two visually adjoining surfaces having different coefficients of reflection. Energy is reflected from each of the positions located on the boundary receiving the light spots. An optical receiving arrangement detects the reflected energy from each of the positions. Changes in reflected energy at one or more of the positions is indicative of eye movement.
摘要翻译：提供了用于以非侵入式的方式感测眼睛运动，例如眼球运动的方法和系统。光学传送装置将激光束脉冲转换成多个光点。光点被聚焦，使得它们入射在位于与眼睛运动的移动一致的边界上的对应的多个位置上。边界可以由具有不同反射系数的两个视觉上相邻的表面限定。能量从位于接收光点的边界上的每个位置反射。光接收装置从每个位置检测反射能量。在一个或多个位置的反射能量的变化表示眼睛运动。

7. 发明授权

US09545338B2 System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser 有权
$System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser$
标题翻译：用于通过激光改善人体镜片的调节幅度和增加屈光力的系统和方法
公开(公告)号：US09545338B2
公开(公告)日：2017-01-17
申请号：US12217285
申请日：2008-07-02
申请人： Rudolph W. Frey , Gary P. Gray , Jerome R. Kuszak
发明人： Rudolph W. Frey , Gary P. Gray , Jerome R. Kuszak
IPC分类号： A61F9/008
CPC分类号： A61F9/00838 , A61F9/008 , A61F9/00827 , A61F2009/0087 , A61F2009/00887 , A61F2009/00897
摘要： A system and method for increasing the amplitude of accommodation and/or changing the refractive power of lens material of a natural crystalline lens is provided. Generally, there is provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of patterns results in the increased accommodative amplitude and/or refractive power of the lens. There is further provided a system and method of treating presbyopia by increasing both the flexibility of the human lens and the depth of field of the eye.
摘要翻译：提供了一种用于增加调节幅度和/或改变天然晶状体的透镜材料的屈光度的方法。通常，提供了用于以多个图案将激光束传送到眼睛的透镜的方法和系统，导致增加的调节幅度和/或屈光力的透镜。还提供了通过增加人体晶状体的灵活性和眼睛的景深来治疗老花眼的系统和方法。

8. 发明申请

US20140066908A9 System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser 有权
$System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser$
标题翻译：用于通过激光改善人体镜片的调节幅度和增加屈光力的系统和方法
公开(公告)号：US20140066908A9
公开(公告)日：2014-03-06
申请号：US12217285
申请日：2008-07-02
申请人： Rudolph W. Frey , Gary P. Gray , Jerome R. Kuszak
发明人： Rudolph W. Frey , Gary P. Gray , Jerome R. Kuszak
IPC分类号： A61F9/008
CPC分类号： A61F9/00838 , A61F9/008 , A61F9/00827 , A61F2009/0087 , A61F2009/00887 , A61F2009/00897
摘要： A system and method for increasing the amplitude of accommodation and/or changing the refractive power of lens material of a natural crystalline lens is provided. Generally, there is provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of patterns results in the increased accommodative amplitude and/or refractive power of the lens. There is further provided a system and method of treating presbyopia by increasing both the flexibility of the human lens and the depth of field of the eye.
摘要翻译：提供了一种用于增加调节幅度和/或改变天然晶状体的透镜材料的屈光度的方法。通常，提供了用于以多个图案将激光束传送到眼睛的透镜的方法和系统，导致增加的调节幅度和/或屈光力的透镜。还提供了通过增加人体晶状体的灵活性和眼睛的景深来治疗老花眼的系统和方法。

9. 发明授权

US08382745B2 Laser system and method for astigmatic corrections in association with cataract treatment 有权
标题翻译：与白内障治疗相关的散光矫正的激光系统和方法
公开(公告)号：US08382745B2
公开(公告)日：2013-02-26
申请号：US12831845
申请日：2010-07-07
申请人： Ramón Naranjo-Tackman , Jorge Octavio Villar Kuri , Rudolph W. Frey
发明人： Ramón Naranjo-Tackman , Jorge Octavio Villar Kuri , Rudolph W. Frey
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61F9/00827 , A61F9/00838 , A61F2009/0087 , A61F2009/00872 , A61F2009/00887 , A61F2009/00889
摘要： There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane and in conjunction a precise predetermined capsulotomy shot pattern.
摘要翻译：提供了一种用于开发激光系统的系统，装置和方法，其可以创建能够减少散光的精确预定的透明角膜切口。系统，装置和方法进一步提供激光系统，其可以在Bowman膜上或下方提供这些切口，并结合精确的预定的囊切开放模式。

10. 发明申请

US20100004643A1 System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser 有权
$System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser$
标题翻译：用于通过激光改善人体镜片的调节幅度和增加屈光力的系统和方法
公开(公告)号：US20100004643A1
公开(公告)日：2010-01-07
申请号：US12217285
申请日：2008-07-02
申请人： Rudolph W. Frey , Gary P. Gray , Jerome R. Kuszak
发明人： Rudolph W. Frey , Gary P. Gray , Jerome R. Kuszak
IPC分类号： A61F9/008
CPC分类号： A61F9/00838 , A61F9/008 , A61F9/00827 , A61F2009/0087 , A61F2009/00887 , A61F2009/00897
摘要： A system and method for increasing the amplitude of accommodation and/or changing the refractive power of lens material of a natural crystalline lens is provided. Generally, there is provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of patterns results in the increased accommodative amplitude and/or refractive power of the lens. There is further provided a system and method of treating presbyopia by increasing both the flexibility of the human lens and the depth of field of the eye.
摘要翻译：提供了一种用于增加调节幅度和/或改变天然晶状体的透镜材料的屈光度的方法。通常，提供了用于以多个图案将激光束传送到眼睛的透镜的方法和系统，导致增加的调节幅度和/或屈光力的透镜。还提供了通过增加人体晶状体的灵活性和眼睛的景深来治疗老花眼的系统和方法。

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