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1. 发明申请

US20050053647A1 Pharmaceutical product comprising the active substance diamorphine, and its use in a process for treating opiate addiction 审中-公开
标题翻译：包含活性物质二氢吗啡的药物产品及其用于治疗阿片成瘾的方法
公开(公告)号：US20050053647A1
公开(公告)日：2005-03-10
申请号：US10942297
申请日：2004-09-16
申请人： Rudolf Matusch , Bernd Adam , Andreas Koch , Hans-Rainer Hoffmann , Bodo Asmussen
发明人： Rudolf Matusch , Bernd Adam , Andreas Koch , Hans-Rainer Hoffmann , Bodo Asmussen
IPC分类号： A61K9/70 , A61K31/485 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/32 , A61K47/34 , A61P25/04 , A61P25/36
CPC分类号： A61K9/7053 , A61K9/7061 , A61K31/485
摘要： The invention relates to pharmaceutical preparations that are used in a method for treating opiate addiction or opiate dependence, especially heroin dependence. The active substance used is preferably diamorphine and/or one of the pharmaceutically acceptable acid addition salts thereof. The invention also relates to a method for treating opiate dependence.
摘要翻译：本发明涉及用于治疗阿片成瘾或阿片依赖性，特别是海洛因依赖性的方法中的药物制剂。所使用的活性物质优选为二氢吗啡和/或其药学上可接受的酸加成盐之一。本发明还涉及一种治疗阿片依赖性的方法。

2. 发明申请

US20110311593A1 N-HYDROXYLATED AMIDINE-, GUANIDINE- AND/OR AMINOHYDRAZONE-TYPE PRODRUGS FOR APPLICATION ON THE SKIN 审中-公开
标题翻译：用于皮肤应用的N-羟化的氨基酸，胍基和/或氨基酸衍生物类
公开(公告)号：US20110311593A1
公开(公告)日：2011-12-22
申请号：US13148422
申请日：2010-02-05
申请人： Rudolf Matusch , Hans-Rainer Hoffmann , Bodo Asmussen , Andreas Koch
发明人： Rudolf Matusch , Hans-Rainer Hoffmann , Bodo Asmussen , Andreas Koch
IPC分类号： A61K9/00 , C07D401/14 , C07D413/12 , C07D205/04 , A61P17/00 , C07H15/238 , A61K31/397 , A61K31/4439 , A61K31/7056 , A61K31/7052 , C07D413/14 , C07D403/12
CPC分类号： A61K9/0014
摘要： The invention relates to N-hydroxylated amidines, guanidines and aminohydrazones for application on the skin. In particular, the invention relates to transdermal therapeutic systems containing N-hydroxylated amidines, guanidines and aminohydrazones as a prodrug, and to methods for producing and using such systems.
摘要翻译：本发明涉及用于皮肤上的N-羟基化脒，胍和氨基腙。特别地，本发明涉及含有N-羟基化脒，胍和氨基腙作为前药的透皮治疗系统，以及制备和使用该系统的方法。

3. 发明授权

US06379696B1 Therapeutic preparation for the transdermal administration of active substances 失效
标题翻译：用于透皮给药活性物质的治疗剂
公开(公告)号：US06379696B1
公开(公告)日：2002-04-30
申请号：US09068326
申请日：1998-05-05
申请人： Bodo Asmussen , Andreas Koch , Rudolf Matusch
发明人： Bodo Asmussen , Andreas Koch , Rudolf Matusch
IPC分类号： A61F1300
CPC分类号： A61K9/0014 , A61K31/22 , A61K31/366 , A61K47/22
摘要： A therapeutic preparation for the transdermal application of active substances through the skin comprising additives causing an increase in the percutaneous absorption rate of active substances which can normally only insufficiently be absorbed transdermally is characterized by the fact that the additives are HMG-CoA-reductase-inhibitors.
摘要翻译：用于通过皮肤透皮施用活性物质的治疗制剂包括通常仅通过不足够被透皮吸收的活性物质的经皮吸收速率增加的添加剂，其特征在于添加剂是HMG-CoA还原酶抑制剂。

4. 发明授权

US5895660A Deuterated active substances in transdermal application 失效
标题翻译：经皮应用中的氘代活性物质
公开(公告)号：US5895660A
公开(公告)日：1999-04-20
申请号：US666269
申请日：1996-08-15
申请人： Hans-Rainer Hoffmann , Thomas Hille , Andreas Koch , Rudolf Matusch
发明人： Hans-Rainer Hoffmann , Thomas Hille , Andreas Koch , Rudolf Matusch
IPC分类号： A61K9/00 , A61K9/06 , A61K31/05 , A61K31/135 , A61K31/19 , A61K31/20 , A61K31/485 , A61K45/08 , A61P17/00 , A61F13/00
CPC分类号： A61K31/135 , A61K31/05 , A61K31/19 , A61K31/20 , A61K31/485 , Y10S514/946 , Y10S514/947 , Y10S514/969
摘要： A drug for the release of active substances to the skin, which has an increased deuterium portion as compared to the natural isotope distribution.
摘要翻译： PCT No.PCT / EP94 / 04047 Sec。 371日期：1996年8月15日 102（e）日期1996年8月15日PCT 1994年12月6日PCT PCT。 WO95 / 17188 PCT公开号日期：1995年6月29日一种用于向皮肤释放活性物质的药物，其与天然同位素分布相比具有增加的氘部分。

5. 发明授权

US06756052B1 Device and method for increasing the transdermal permeation of medicaments 有权
标题翻译：增加药物透皮渗透的装置和方法
公开(公告)号：US06756052B1
公开(公告)日：2004-06-29
申请号：US09979251
申请日：2001-11-19
申请人： Andreas Koch , Christian von Falkenhausen , Rudolf Matusch , Bernd Adam
发明人： Andreas Koch , Christian von Falkenhausen , Rudolf Matusch , Bernd Adam
IPC分类号： A61F1302
CPC分类号： A61K9/7084 , A61K9/703 , A61K9/7038 , A61K9/7092 , A61K31/485 , A61K31/565 , A61K45/06 , Y10S514/947
摘要： The invention relates to a device and a method for increasing the transdermal permeation of medications. The invention is characterized in that a constituent which effects a local increase in temperature and/or an increase in blood flow or the skin is administered in a addition to the transdermally applied active substance.
摘要翻译：本发明涉及增加药物透皮渗透的装置和方法。本发明的特征在于，在经皮施用的活性物质的添加剂中施用影响局部温度升高和/或血液流动或皮肤增加的成分。

6. 发明授权

US09558889B2 Capacitor device for a conductor loop in a device for the in-sity production of heavy oil and bitumen from oil-sand deposits 有权
标题翻译：用于从油砂沉积物中重油和沥青生产设备的导体回路的电容器
公开(公告)号：US09558889B2
公开(公告)日：2017-01-31
申请号：US14354037
申请日：2012-10-17
申请人： Dirk Diehl , Andreas Koch
发明人： Dirk Diehl , Andreas Koch
IPC分类号： H01G4/30 , E21B43/24 , H01G4/40 , E21B36/04 , H01G4/38 , H01G4/04 , H01G4/228 , H01G4/018 , H01G4/224 , H01G13/00
CPC分类号： H01G4/30 , E21B36/04 , E21B43/24 , E21B43/2401 , H01G4/018 , H01G4/04 , H01G4/224 , H01G4/228 , H01G4/38 , H01G4/40 , H01G13/00 , Y10T29/43
摘要： The embodiments relate to a capacitor device for a conductor loop in a device for the in-situ production of heavy oil and bitumen from oil-sand deposits, characterized by a housing and a capacitor unit arranged therein to compensate for the inductive voltage drop along the conductor loop, wherein there are two connection interfaces, wherein each connection interface is designed for mechanical and electrically conductive connection between the capacitor unit and a conductor element of the conductor loop.
摘要翻译：实施例涉及用于从油砂沉积物原位生产重油和沥青的装置中的导体回路的电容器装置，其特征在于，壳体和电容器单元布置在其中以补偿沿着导体环路，其中有两个连接接口，其中每个连接接口被设计用于电容器单元和导体环路的导体元件之间的机械和导电连接。

7. 发明申请

US20140318227A1 METHOD FOR ASSESSING AN INJECTION BEHAVIOUR OF AT LEAST ONE INJECTION VALVE IN AN INTERNAL COMBUSTION ENGINE AND OPERATING METHOD FOR AN INTERNAL COMBUSTION ENGINE 有权
标题翻译：用于评估内燃机中至少一个喷射阀的喷射行为的方法和用于内燃机的操作方法
公开(公告)号：US20140318227A1
公开(公告)日：2014-10-30
申请号：US14346283
申请日：2012-08-06
申请人： Klaus Joos , Werner Hess , Andreas Koch , Ruben Schlueter , Holger Rapp , Haris Hamedovic , Joerg Koenig , Harry Friedmann , Achim Hirchenhein , Christoph Heisen , Christian Reschke , Stephanie Wirth
发明人： Klaus Joos , Werner Hess , Andreas Koch , Ruben Schlueter , Holger Rapp , Haris Hamedovic , Joerg Koenig , Harry Friedmann , Achim Hirchenhein , Christoph Heisen , Christian Reschke , Stephanie Wirth
IPC分类号： F02M65/00 , G01M15/04
CPC分类号： F02M65/001 , F02D41/221 , F02D41/2438 , F02D41/2458 , F02D41/402 , F02D2200/0618 , F02D2200/702 , G01M15/042 , Y02T10/44
摘要： A method for assessing an injection behavior of at least one injection valve of an internal combustion engine includes putting the internal combustion engine into a special operating mode defined by control parameters and operating the engine in the special operating mode during a diagnostic time period, at least one operating parameter of the internal combustion engine being determined at least during the diagnostic time period, and at least one quantity characterizing the injection behavior of the at least one injection valve being evaluated at least during a segment of the diagnostic time period and being evaluated on the basis of the at least one operating parameter.
摘要翻译：用于评估内燃机的至少一个喷射阀的喷射行为的方法包括将内燃机置于由控制参数限定的特殊操作模式中，并且在诊断时间段期间至少在特殊操作模式下操作发动机至少在诊断时间段期间确定内燃机的一个操作参数，并且至少一个表征至少一个喷射阀的喷射行为的量至少在诊断时间段的一段被评估，并被评估所述至少一个操作参数的基础。

8. 发明授权

US08455641B2 Method for producing 4,4′-(propane-1,2-diyl)-dipiperazine-2,6-dione 失效
标题翻译：制备4,4' - （丙烷-1,2-二基） - 二哌嗪-2,6-二酮的方法
公开(公告)号：US08455641B2
公开(公告)日：2013-06-04
申请号：US12516348
申请日：2007-11-23
申请人： Andreas Koch , Erwin Neufellner
发明人： Andreas Koch , Erwin Neufellner
IPC分类号： C07D241/04
CPC分类号： C07D241/08 , C07C229/16
摘要： A method for preparing compounds of the formula (I) by the cyclization of tetraacetic acid alkyl esters of the formula (II) in the presence of ammonia and formamide as well as to the compounds of the formula (II), which are used in this method.
摘要翻译：通过在氨和甲酰胺的存在下使式（II）的四乙酸烷基酯与式（II）化合物在式方法。

9. 发明授权

US07598872B2 Method for recognizing identification media 有权
标题翻译：识别识别媒体的方法
公开(公告)号：US07598872B2
公开(公告)日：2009-10-06
申请号：US10591415
申请日：2005-02-28
申请人： Marcel Plūss , Andreas Koch , Peter Hausmann
发明人： Marcel Plūss , Andreas Koch , Peter Hausmann
IPC分类号： H04Q5/22 , G08B13/14
CPC分类号： G06K7/0008 , G06K7/10039 , G06K7/10128
摘要： The invention relates to a method for recognizing identification media in the communication area of a write/read device functioning according to the principle of inductive coupling in the MHz range, wherein an antenna is used for transmitting and receiving HF signals, in addition to a circuit for transmitting HF signals with a standard transmitter power output and a logic circuit for evaluating communication between a write/read device and an identification medium. A short inquiry signal consisting of several fundamental components of the HF field and having a standard transmission power output is periodically transmitted via a transmission path and the antenna and a response signal is detected on the antenna. The response signal is compared to a reference signal and a communication signal is transmitted in order to recognize an identification medium in the event that the response signal is different from the reference signal. This enables energy-saving, reliable recognition of identification media occurring in the field of communications for subsequent communication with the write/read device, particularly with respect to battery-operated write/read devices.
摘要翻译：本发明涉及一种用于识别根据在MHz范围内的电感耦合原理起作用的写/读设备的通信区域中的识别介质的方法，其中天线用于发送和接收HF信号，除了电路用于发送具有标准发射机功率输出的HF信号和用于评估写/读设备和识别介质之间的通信的逻辑电路。由HF场的几个基本组成部分和具有标准传输功率输出的短询问信号通过传输路径周期性地发送，并且在天线上检测到响应信号。将响应信号与参考信号进行比较，并且在响应信号与参考信号不同的情况下，传送通信信号以识别识别介质。这使得能够对通信领域中出现的识别介质进行节能，可靠的识别，以便随后与写/读设备进行通信，特别是关于电池供电的写/读设备。

10. 发明申请

US20090169601A1 Transdermal Therapeutic System for Administering Lipophilic and/or Sparingly Skin- Permeable Active Substances 有权
标题翻译：用于管理亲脂性和/或微量透皮活性物质的透皮治疗系统
公开(公告)号：US20090169601A1
公开(公告)日：2009-07-02
申请号：US12083888
申请日：2006-10-04
申请人： Andreas Koch , Christoph Schmitz , Rolf Pracht , Mohammad Sameti
发明人： Andreas Koch , Christoph Schmitz , Rolf Pracht , Mohammad Sameti
IPC分类号： A61K9/70 , A61K31/4375 , A61K31/506 , A61K31/437
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7084
摘要： A transdermal therapeutic system for administering lipophilic, poorly water-soluble and/or sparingly skin-permeable pharmaceutical active substances. The active substance is present in a multi-component enhancer system consisting of 4 components and each component of the multi-component enhancer system is selected from a different one of the substance groups: a) terpenes, b) cyclic glucitol ethers, c) medium-chain triglycerides of capric and caprylic acid and/or of linoleic acid; and d) longer-chain alcohols having a chain length of 8 or more carbon atoms.
摘要翻译：一种用于施用亲脂性，水溶性差和/或微量透皮的药物活性物质的透皮治疗系统。活性物质存在于由4种组分组成的多组分增强剂体系中，多组分增强子系统的每种组分选自不同的物质组：a）萜烯，b）环状糖醇醚，c）中等癸酸和辛酸和/或亚油酸的链状甘油三酸酯; 和d）链长为8个或更多个碳原子的长链醇。

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