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1. 发明申请

US20110024186A1 LEAD APPARATUS 有权
标题翻译：铅装置
公开(公告)号：US20110024186A1
公开(公告)日：2011-02-03
申请号：US12795236
申请日：2010-06-07
申请人： Rogier Receveur , Jean Joseph Gerardus Rutten , Karel F.A.A. Smits , Nicolaas M. Lokhoff , Sylvia Weijzen-Engels , Didier Billy , Tim Dirk Jan Jongen , Lilian Kornet
发明人： Rogier Receveur , Jean Joseph Gerardus Rutten , Karel F.A.A. Smits , Nicolaas M. Lokhoff , Sylvia Weijzen-Engels , Didier Billy , Tim Dirk Jan Jongen , Lilian Kornet
IPC分类号： H01B5/00 , H01R43/00
CPC分类号： A61N1/056 , A61N1/3756
摘要： A lead including one or more electrodes (e.g., electrodes, such as those having circuitry associated therewith).
摘要翻译：包括一个或多个电极（例如，电极，例如具有与其相关联的电路的电极）的引线。

2. 发明授权

US08744548B2 Lead apparatus 有权
标题翻译：铅装置
公开(公告)号：US08744548B2
公开(公告)日：2014-06-03
申请号：US12795236
申请日：2010-06-07
申请人： Rogier Receveur , Jean Joseph Gerardus Rutten , Karel F. A. A. Smits , Nicolaas M Lokhoff , Sylvia Weijzen-Engels , Didier Billy , Tim Dirk Jan Jongen , Lilian Kornet
发明人： Rogier Receveur , Jean Joseph Gerardus Rutten , Karel F. A. A. Smits , Nicolaas M Lokhoff , Sylvia Weijzen-Engels , Didier Billy , Tim Dirk Jan Jongen , Lilian Kornet
IPC分类号： A61B5/042 , A61N1/05
CPC分类号： A61N1/056 , A61N1/3756
摘要： A lead including one or more electrodes having circuitry associated therewith. Each such electrode includes a circuit extending along and conforming to at least a portion of an inner surface of the electrode. The circuit includes an isolation substrate contacting at least a portion of the inner surface of the cylindrical electrode portion, a first contact electrically isolated from the electrode portion by the isolation substrate and an integrated circuit electrically coupled to the first contact and the electrode.
摘要翻译：包括具有与其相关的电路的一个或多个电极的引线。每个这样的电极包括沿着电极的内表面的至少一部分延伸并且与电极的内表面的至少一部分一致的电路。电路包括与圆柱形电极部分的内表面的至少一部分接触的隔离衬底，通过隔离衬底与电极部分电隔离的第一接触和电耦合到第一接触和电极的集成电路。

3. 发明授权

US08840913B2 Malleable multi-component implants and materials therefor 有权
标题翻译：可塑性多组分植入物及其材料
公开(公告)号：US08840913B2
公开(公告)日：2014-09-23
申请号：US12056549
申请日：2008-03-27
申请人： William F. McKay , Jeffrey L. Scifert , Kathy L. Remsen , Didier Billy , Mirian Gillissen , Scott M. Vickers
发明人： William F. McKay , Jeffrey L. Scifert , Kathy L. Remsen , Didier Billy , Mirian Gillissen , Scott M. Vickers
IPC分类号： A61K9/00 , A61F2/02 , A61K38/16 , A61P19/00 , A61L27/26 , A61L27/54
CPC分类号： A61K38/1875 , A61K9/0024 , A61L27/26 , A61L27/54 , A61L2300/414 , A61L2430/02 , C08L5/04 , C08L89/06
摘要： Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The malleable medical materials can be used treat bone or other tissue defects in patients, including in conjunction with biologically active factors such as osteogenic proteins. Also described are methods and materials that can be used to prepare the malleable medical materials.
摘要翻译：描述了包括矿物颗粒，不溶性胶原纤维和形成凝胶的多糖组分和/或另外添加的凝胶形成剂的可植入的可延展的医用材料。可延展的医疗材料可用于治疗患者的骨骼或其他组织缺陷，包括结合生物活性因子如成骨蛋白。还描述了可用于制备可延展的医疗材料的方法和材料。

4. 发明申请

US20100034794A1 ENDOTHELIAL PROGENITOR CELL COMPOSITIONS AND NEOVASCULARIZATION 审中-公开
标题翻译：内源性原核细胞组成和新生血管
公开(公告)号：US20100034794A1
公开(公告)日：2010-02-11
申请号：US12443951
申请日：2007-10-02
申请人： Barry W.A. van der Strate , Guido Krenning , Brian C.A. Fernandes , Martin Harmsen , Marja J.A. van Luyn , Didier Billy , Marc Hendriks
发明人： Barry W.A. van der Strate , Guido Krenning , Brian C.A. Fernandes , Martin Harmsen , Marja J.A. van Luyn , Didier Billy , Marc Hendriks
IPC分类号： A61K35/12
CPC分类号： A61K38/1866 , A61K35/44 , A61K38/1825 , A61K2300/00
摘要： Methods and compositions are provided for inducing neovascularization in injured tissues with endothelial progenitor cells (EPCs). Mixtures of purified CD34+ endothelial progenitors and purified CD14+ monocytes, or products of an in vitro co-culture of purified CD34+ endothelial progenitor cells and purified CD14+ monocytes provide neovascularization after administration to a subject having a tissue injury, such as an ischemic injury.
摘要翻译：提供了用于在内皮祖细胞（EPCs）诱导损伤组织中新血管形成的方法和组合物。纯化的CD34 +内皮祖细胞和纯化的CD14 +单核细胞的混合物或纯化的CD34 +内皮祖细胞和纯化的CD14 +单核细胞的体外共培养物的产物在给予具有组织损伤（例如缺血性损伤）的受试者后提供新生血管形成。

5. 发明申请

US20080208312A1 Stent Graft With Strips to Promote Localized Healing 审中-公开
标题翻译：支架移植，促进局部治疗
公开(公告)号：US20080208312A1
公开(公告)日：2008-08-28
申请号：US11464585
申请日：2006-08-15
申请人： Brian Kwitkin , Didier Billy , Marc Hendriks
发明人： Brian Kwitkin , Didier Billy , Marc Hendriks
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/067 , A61F2002/075 , A61F2250/0067
摘要： An endoluminal stent graft includes segments of a healing promoter to promote the “healing in” of the distal and/or proximal neck(s) of the endoluminal stent graft in a vessel, thus reducing the risk of migration and the occurrence of endoleaks that can formed at the side of the neck(s) and the consequent feeding of the aneurysm sac. In some applications, the segments of the healing promoter are located within a proximal anchor region located near the proximal neck opening of the endoluminal stent graft and, optionally, within one or more distal anchor regions located near one or more distal neck openings of the endoluminal stent graft. In other applications, the segments of the healing promoter are located within the proximal anchor region, but not the distal anchor region.
摘要翻译：腔内支架移植物包括愈合促进剂的部分，以促进血管内腔内支架移植物的远端和/或近端颈部的“愈合”，从而降低迁移的风险和可产生内漏的发生形成在颈部的一侧，随之而来的动脉瘤囊的供给。在一些应用中，愈合促进剂的部分位于位于内腔支架移植物的近端颈部开口附近的近端锚定区域中，并且可选地位于位于内腔内的一个或多个远端颈部开口附近的一个或多个远侧锚定区域内支架移植在其他应用中，愈合促进剂的区段位于近端锚定区域内，但不位于远端锚定区域。

6. 发明申请

US20070239267A1 Stent Graft With Healing Promoting Necks 审中-公开
标题翻译：支架治疗促进脖子
公开(公告)号：US20070239267A1
公开(公告)日：2007-10-11
申请号：US11277643
申请日：2006-03-28
申请人： Marc Hendriks , Edouard Koullick , Jeff Elkins , Didier Billy , Brian Kwitkin , Paul Van Bilsen , Jack Chu , Brian Raze
发明人： Marc Hendriks , Edouard Koullick , Jeff Elkins , Didier Billy , Brian Kwitkin , Paul Van Bilsen , Jack Chu , Brian Raze
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B2017/00893 , A61F2/0077 , A61F2/89 , A61F2002/067 , A61F2002/075 , A61F2002/8486 , A61F2250/0067
摘要： An endoluminal stent graft includes a healing-promoting material to enhance the “healing” of the proximal and/or distal neck(s) of the endoluminal stent graft and the vessel wall; the risk of migration and the occurrence of Type 1 endoleaks is reduced. The healing-promoting material is located within a proximal anchor region located near the proximal neck opening of the endoluminal stent graft and optionally within one or more distal anchor regions located near one or more distal neck openings of the endoluminal stent graft.
摘要翻译：腔内支架移植物包括促进愈合的材料，以增强内腔支架移植物和血管壁的近端和/或远端颈部的“愈合”; 迁移的风险和1型内漏的发生减少。愈合促进材料位于位于腔内支架移植物的近端颈部开口附近的近端锚定区域中，并且任选地位于位于腔内支架移植物的一个或多个远端颈部开口附近的一个或多个远侧锚定区域内。

7. 发明申请

US20060257449A1 Methods, compositions, systems, and devices for bone fusion 审中-公开
标题翻译：用于骨融合的方法，组合物，系统和装置
公开(公告)号：US20060257449A1
公开(公告)日：2006-11-16
申请号：US11129977
申请日：2005-05-16
申请人： Didier Billy , Frank Everaerts , Michel Verhoeven
发明人： Didier Billy , Frank Everaerts , Michel Verhoeven
IPC分类号： A61K35/12 , A61K38/18
CPC分类号： A61L27/46 , A61L2430/02
摘要： The present invention is directed to methods, compositions, systems, and medical devices for fusing bone.
摘要翻译：本发明涉及用于融合骨的方法，组合物，系统和医疗装置。

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