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    • 5. 发明申请
    • In Situ Blood Vessel and Aneurysm Treatment
    • 原位血管和动脉瘤治疗
    • US20080249511A1
    • 2008-10-09
    • US12132355
    • 2008-06-03
    • Jack ChuBrian Raze
    • Jack ChuBrian Raze
    • A61M31/00A61M25/00
    • A61M5/00A61L31/16
    • Treatment of aneurysmal blood vessels with local delivery of therapeutic agents thereby reduces or lessens the severity of an aneurysm, and, where used in conjunction with the placement of an excluding device, provides for more rapid recovery of the blood vessel from any disturbance occurring during placement of the excluding device. Therapeutic agents are placed in the aneurysmal site in a time-release carrier medium, such that the therapeutic agent is released into the aneurysmal site over a period of time without the need to provide systemic introduction of the therapeutic agent. The carrier may be introduced through the patient's dermis, such as with the use of a laparoscope, or intravascularly, through the use of a catheter. The carrier may be in a solid matrix, viscous liquid or liquid form.
    • 用局部递送治疗剂治疗动脉瘤血管,从而降低或减轻动脉瘤的严重程度,并且在与排除装置的放置一起使用时,可以从放置期间发生的任何干扰提供更快速的血管恢复 的排除设备。 将治疗剂置于时间释放载体培养基的动脉瘤部位,使得治疗剂在一段时间内释放到动脉瘤部位,而不需要提供治疗剂的全身引入。 可以通过使用导管将载体例如通过使用腹腔镜或血管内引入患者真皮中。 载体可以是固体基质,粘稠液体或液体形式。
    • 6. 发明授权
    • In situ blood vessel and aneurysm treatment
    • 原位血管和动脉瘤治疗
    • US08597674B2
    • 2013-12-03
    • US12132355
    • 2008-06-03
    • Jack ChuBrian Raze
    • Jack ChuBrian Raze
    • A61F2/00A61F2/06A61M29/00
    • A61M5/00A61L31/16
    • Treatment of aneurysmal blood vessels with local delivery of therapeutic agents thereby reduces or lessens the severity of an aneurysm, and, where used in conjunction with the placement of an excluding device, provides for more rapid recovery of the blood vessel from any disturbance occurring during placement of the excluding device. Therapeutic agents are placed in the aneurysmal site in a time-release carrier medium, such that the therapeutic agent is released into the aneurysmal site over a period of time without the need to provide systemic introduction of the therapeutic agent. The carrier may be introduced through the patient's dermis, such as with the use of a laparoscope, or intravascularly, through the use of a catheter. The carrier may be in a solid matrix, viscous liquid or liquid form.
    • 用局部递送治疗剂治疗动脉瘤血管,从而降低或减轻动脉瘤的严重程度,并且在与排除装置的放置一起使用时,可以从放置期间发生的任何干扰提供更快速的血管恢复 的排除设备。 将治疗剂置于时间释放载体培养基的动脉瘤部位,使得治疗剂在一段时间内释放到动脉瘤部位,而不需要提供治疗剂的全身引入。 可以通过使用导管将载体例如通过使用腹腔镜或血管内引入患者真皮中。 载体可以是固体基质,粘稠液体或液体形式。
    • 9. 发明授权
    • Device for delivering a sensor to the endovascular system and method of use
    • 将传感器传送到血管内系统的装置和使用方法
    • US07060038B2
    • 2006-06-13
    • US10422639
    • 2003-04-24
    • Michel LetortBrian Raze
    • Michel LetortBrian Raze
    • A61B5/00
    • A61B5/411A61B5/0031A61B5/02014
    • A delivery system for delivering a sensor to a body cavity includes a catheter and sheath slidably or rotatably coupled to the catheter. The sheath may be retractable and peelable. The delivery device may include an expandable balloon or a crushable material capable of moving the sensor laterally away from the catheter, to the target site. One embodiment of the delivery system includes a deployment device comprising a cord operably engaged with a pulley, and attached at the distal end to a cap engaged with the sensor. Another embodiment of the delivery system comprises a catheter having a chamber that can accommodate the sensor, and a sheath slidably coupled to the exterior of the catheter, and covering the chamber when the sheath is in the closed position. Further included is a method of delivering a sensor to a body cavity using any of the embodiments of the delivery system.
    • 用于将传感器传送到体腔的递送系统包括可滑动地或可旋转地联接到导管的导管和鞘。 护套可以是可伸缩的和可剥离的。 输送装置可以包括能够将传感器横向远离导管移动到目标部位的可膨胀气囊或可压碎材料。 递送系统的一个实施例包括展开装置,其包括与滑轮可操作地接合的绳索,并且在远端处附接到与传感器接合的盖。 递送系统的另一实施例包括具有容纳传感器的腔室的导管,以及可滑动地联接到导管外部的护套,并且当护套处于关闭位置时覆盖腔室。 还包括使用传送系统的任何实施例将传感器传送到体腔的方法。