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1. 发明授权

US06831539B1 Magnetic microactuator for disc with integrated head connections and limiters drives 失效
标题翻译：具有集成头连接和限位器驱动的磁盘的磁性微致动器
公开(公告)号：US06831539B1
公开(公告)日：2004-12-14
申请号：US10650392
申请日：2003-08-28
申请人： Roger Lee Hipwell, Jr. , Andrew David White , Zine-Eddine Boutaghou , Wayne Allen Bonin
发明人： Roger Lee Hipwell, Jr. , Andrew David White , Zine-Eddine Boutaghou , Wayne Allen Bonin
IPC分类号： G11B548
CPC分类号： G11B5/5552 , G11B5/4826 , H02K41/0356 , Y10T29/49021 , Y10T29/49032
摘要： A microactuator design and fabrication method for an improved magnetic microactuator incorporating mechanical stroke limiters and integrated connections between the flex on suspension and slider. The stroke limiters, also referred to as bumper system, and integrated connections enable low power, mechanically robust operation of the microactuator during high seek operations. In addition, improved head gimbal assembly yield results due to the integrated head connections formed on the microactuator.
摘要翻译：一种用于改进的磁性微型致动器的微型致动器设计和制造方法，其包括机械行程限制器以及悬架和滑块之间的柔性连接。行程限制器（也称为保险杠系统）和集成连接使得在高寻找操作期间微型致动器能够实现低功率，机械稳定的操作。此外，由于在微致动器上形成的集成头连接，改进的头万向节组装产生结果。

2. 发明授权

US07502204B2 Structures for attaching a head gimbal assembly and an actuator arm 失效
标题翻译：用于安装头部万向架组件和致动器臂的结构
公开(公告)号：US07502204B2
公开(公告)日：2009-03-10
申请号：US11303613
申请日：2005-12-16
申请人： Andrew David White , David Gerard Wobbe , Andrew Kelly Putzy , Zine-Eddine Boutaghou
发明人： Andrew David White , David Gerard Wobbe , Andrew Kelly Putzy , Zine-Eddine Boutaghou
IPC分类号： G11B5/48
CPC分类号： G11B5/4833
摘要： An assembly for attaching a first element to a second element. The assembly includes a first non-metallic connecting member. The first non-metallic connecting member includes a first member having a first surface and a second member. The second member extends substantially perpendicular from a first end adjacent the first surface to a second end and has an outer surface. Apertures in the first and second elements receive the second member.
摘要翻译：一种用于将第一元件附接到第二元件的组件。组件包括第一非金属连接构件。第一非金属连接构件包括具有第一表面和第二构件的第一构件。第二构件从邻近第一表面的第一端基本上垂直延伸到第二端并且具有外表面。第一和第二元件中的孔接收第二构件。

3. 发明授权

US07450342B2 Composite head-electrical conditioner assembly 有权
标题翻译：复合头电器组装
公开(公告)号：US07450342B2
公开(公告)日：2008-11-11
申请号：US11079052
申请日：2005-03-14
申请人： Andrew David White , Roger Lee Hipwell, Jr. , John R. Pendray , Bradley Jay VerMeer
发明人： Andrew David White , Roger Lee Hipwell, Jr. , John R. Pendray , Bradley Jay VerMeer
IPC分类号： G11B5/48 , G11B5/60
CPC分类号： G11B5/4853 , G11B5/484
摘要： A composite head-electrical conditioner assembly that includes a slider with a transducer head and transducer bond pads. The transducer bond pads communicate a transducer level electrical signal with the transducer head. An integrated circuit substrate has a conditioning circuit and first substrate bond pads electrically connected to the transducer bond pads. The integrated circuit substrate has second substrate bond pads with a conditioned electrical signal that is transmittable over a circuit. The slider is rigidly mounted to the integrated circuit substrate to form an assembly that is flexibly mountable. A thermal isolation space is provided between the transducer and the conditioning circuit. The integrated circuit can be in the form of a cap that provides windage reduction.
摘要翻译：一种复合头 - 电调节器组件，其包括具有换能器头和换能器接合垫的滑块。传感器接合焊盘将传感器电平信号与换能器头通信。集成电路基板具有调节电路和电连接到换能器接合焊盘的第一基板接合焊盘。集成电路衬底具有第二衬底接合焊盘，其具有可通过电路传输的经调节的电信号。滑块刚性地安装到集成电路基板上以形成可灵活安装的组件。在换能器和调节电路之间设有隔热空间。集成电路可以是提供减少风量的帽子的形式。

4. 发明授权

US06624177B1 Matrix metalloproteinase inhibitors and their therapeutic uses 失效
标题翻译：基质金属蛋白酶抑制剂及其治疗用途
公开(公告)号：US06624177B1
公开(公告)日：2003-09-23
申请号：US09254384
申请日：1999-03-02
申请人： Patrick Michael O'Brien , Joseph Armand Picard , Drago Robert Sliskovic , Andrew David White
发明人： Patrick Michael O'Brien , Joseph Armand Picard , Drago Robert Sliskovic , Andrew David White
IPC分类号： C07D20982
CPC分类号： C07D307/91 , A61K31/343 , A61K31/381 , C07C311/19 , C07C2603/18 , C07D333/76
摘要： The present invention relates to a method of inhibiting matrix metalloproteinases using compounds that are dibenzofuran sulfonamide derivatives having the Formula I More particularly, the present invention relates to a method of treating diseases in which matrix melatoproteinases are involved such as multiple sclerosis, atherosclerotic plaque rupture, restenosis, aortic aneurism, heart failure, periodontal disease, corneal ulceration, burns, decubital ulcers, chronic ulcers or wounds, cancer metastasis, tumor angiogenesis, arthritis, or other autoimmune or inflammatory diseases dependent upon tissue invasion by leukocytes.
摘要翻译：本发明涉及使用具有式IIIO的二苯并呋喃磺酰胺衍生物的化合物抑制基质金属蛋白酶的方法，本发明涉及一种治疗涉及多发性硬化症，动脉粥样硬化斑块破裂，再狭窄的基质蛋白酶的疾病的方法，主动脉瘤，心力衰竭，牙周病，角膜溃疡，烧伤，褥疮性溃疡，慢性溃疡或创伤，癌症转移，肿瘤血管生成，关节炎或依赖于白细胞组织侵袭的其他自身免疫性或炎性疾病。

5. 发明授权

US06541521B1 Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases 失效
标题翻译：苯丁酸及其衍生物作为基质金属蛋白酶的抑制剂
公开(公告)号：US06541521B1
公开(公告)日：2003-04-01
申请号：US09351549
申请日：1999-07-12
申请人： Claude Forsey Purchase, Jr. , Bruce David Roth , Andrew David White
发明人： Claude Forsey Purchase, Jr. , Bruce David Roth , Andrew David White
IPC分类号： A61K31195
CPC分类号： C07D213/82 , C07C233/54 , C07C233/55 , C07C233/63 , C07C233/81 , C07C235/56 , C07C251/48 , C07C2601/14 , C07D333/38
摘要： Benzene butyric acid compounds and derivatives are described as well as methods for the preparation and pharmaceutical compositions of same, which are useful as inhibitors of matrix metalloproteinases, particularly gelatinase A, collagenase-3, and stromelysin-1 and for the treatment of multiple sclerosis, atherosclerotic plaque rupture, aortic aneurysm, heart failure, left ventricular dilation, restenosis, periodontal disease, corneal ulceration, treatment of burns, decubital ulcers, wound healing, cancer, inflammation, pain, arthritis, osteoporosis, renal disease, or other autoimmune or inflammatory disorders dependent upon tissue invasion by leukocytes or other activated migrating cells, acute and chronic neurodegenerative disorders including stroke, head trauma, spinal cord injury, Alzheimer's disease, amyotrophic lateral sclerosis, cerebral amyloid angiopathy, AIDS, Parkinson's disease, Huntington's disease, prion diseases, myasthenia gravis, and Duchenne's muscular dystrophy.
摘要翻译：苯丁酸化合物和衍生物以及其制备方法及其药物组合物的描述，其可用作基质金属蛋白酶抑制剂，特别是明胶酶A，胶原酶-3和溶基质溶解素-1以及用于治疗多发性硬化，动脉粥样硬化斑块破裂，主动脉瘤，心力衰竭，左心室扩张，再狭窄，牙周病，角膜溃疡，烧伤治疗，褥疮溃疡，伤口愈合，癌症，炎症，疼痛，关节炎，骨质疏松症，肾脏疾病或其他自身免疫或炎症依赖于白细胞或其他激活的迁移细胞的组织侵袭的疾病，急性和慢性神经变性疾病，包括中风，头部创伤，脊髓损伤，阿尔茨海默病，肌萎缩性侧索硬化，脑淀粉样血管病，艾滋病，帕金森病，亨廷顿病，朊病毒疾病，重症肌无力和Duchenne肌营养不良症。

6. 发明授权

US06307089B2 Biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases 失效
公开(公告)号：US06307089B2
公开(公告)日：2001-10-23
申请号：US09736802
申请日：2000-12-14
申请人： Claude Forsey Purchase, Jr. , Bruce David Roth , Gerald Paul Schielke , Lary Craswell Walker , Andrew David White
发明人： Claude Forsey Purchase, Jr. , Bruce David Roth , Gerald Paul Schielke , Lary Craswell Walker , Andrew David White
IPC分类号： C07C6976
CPC分类号： C07C323/63 , C07C59/56 , C07C59/84 , C07C59/88 , C07C59/90 , C07C69/738 , C07C251/48 , C07C251/86 , C07C255/64
摘要： Biphenyl butyric acid compounds and derivatives are described as well as acid methods for the preparation and pharmaceutical compositions of same, which are useful as inhibitors of matrix metalloproteinases, particularly gelatinase A (72 kD gelatinase) and stromelysin-1 and for the treatment of multiple sclerosis, atherosclerotic plaque rupture, aortic aneurism, heart failure, restenosis, periodontal disease, corneal ulceration, treatment of burns, decubital ulcers, wound healing, cancer, inflammation, pain, arthritis, or other autoimmune or inflammatory disorders dependent upon tissue invasion by leukocytes or other activated migrating cells.

7. 发明授权

US07469838B2 Detectable components and detection apparatus for detecting such components 有权
标题翻译：用于检测这些部件的可检测部件和检测装置
公开(公告)号：US07469838B2
公开(公告)日：2008-12-30
申请号：US10863513
申请日：2004-06-09
申请人： Colin Philip Brooks , David Bernard Mapleston , Peter Robert Symons , Andrew David White
发明人： Colin Philip Brooks , David Bernard Mapleston , Peter Robert Symons , Andrew David White
IPC分类号： G06K19/06 , G06K7/08
CPC分类号： G06K7/10128 , G01R33/02 , G01V3/081 , G01V15/00 , G06K7/0008 , G06K19/0723 , G07D7/04
摘要： A detectable component has a first inductive coupler (L;M) adapted to couple inductively to a second inductive coupler (L1) of a detection apparatus when the detectable component is in range of or coupled to the detection apparatus. The first inductive coupler has a resistive component (M) with a resistance that varies with magnetic field to cause modulation of a carrier signal supplied to the second inductive coupler of the detection apparatus, the detectable component having a characteristic signature that enables the detectable component to be distinguished by the detection apparatus from other such detectable components having different characteristic signatures.
摘要翻译：当可检测组件在检测装置的范围内或耦合到检测装置时，可检测组件具有适于将感应耦合到检测装置的第二电感耦合器（L1）的第一感应耦合器（L; M）。第一电感耦合器具有电阻分量（M），其电阻随磁场而变化，从而调制提供给检测装置的第二感应耦合器的载波信号，该可检测部件具有使得可检测部件能够通过检测装置与具有不同特性特征的其它这种可检测组件区分开来。

8. 发明授权

US07248892B2 Electrical devices 有权
标题翻译：电气设备
公开(公告)号：US07248892B2
公开(公告)日：2007-07-24
申请号：US10477733
申请日：2002-05-14
申请人： Andrew David White , Marc Adrian Borrett , David Bernard Mapleston
发明人： Andrew David White , Marc Adrian Borrett , David Bernard Mapleston
IPC分类号： H04M1/00 , H04B1/38
CPC分类号： H04M1/0256 , B23Q1/0009 , H04M1/0283 , H04M1/72525 , H04M1/72544 , H04M1/72561 , H04M1/72575 , H04M2250/22
摘要： An electrical device such as a portable communications device, domestic or personal care appliance has a main body adapted to couple to an accessory which may be in the form of a tool attachable to the main body or a housing portion. The accessory carries a passive data storage device having a memory (59) storing control data for controlling an operation or affecting a function of the device. The passive data storage device is arranged to derive a power supply from the main body when a first coupler carried by the main body is placed in proximity to a second coupler carried by the accessory (3). Where the electrical device is a portable communications device, then the accessory may be, for example, a fascia. The coupling between the first and second couplers may be inductive or capacitive.
摘要翻译：诸如便携式通信设备，家用或个人护理用具的电气设备具有适于联接到可附接到主体或壳体部分的工具形式的附件的主体。该附件携带具有存储器（59）的无源数据存储设备，存储器（59）存储用于控制操作或影响设备功能的控制数据。无源数据存储装置被布置成当由主体承载的第一耦合器放置在由附件（3）承载的第二耦合器附近时从主体导出电力供应。在电气设备是便携式通信设备的情况下，附件可以是例如面板。第一和第二耦合器之间的耦合可以是电感的或电容的。

9. 发明授权

US06906092B2 Method of inhibiting matrix metalloproteinases 失效
标题翻译：抑制基质金属蛋白酶的方法
公开(公告)号：US06906092B2
公开(公告)日：2005-06-14
申请号：US10603677
申请日：2003-06-25
申请人： Patrick Michael O'Brien , Joseph Armand Picard , Drago Robert Sliskovic , Andrew David White
发明人： Patrick Michael O'Brien , Joseph Armand Picard , Drago Robert Sliskovic , Andrew David White
IPC分类号： A61K31/343 , A61K31/381 , A61P9/10 , A61P17/02 , A61P27/02 , C07C311/19 , C07D307/91 , C07D333/76 , A61K31/40
CPC分类号： C07D307/91 , A61K31/343 , A61K31/381 , C07C311/19 , C07C2603/18 , C07D333/76
摘要： The present invention relates to a method of inhibiting matrix metalloproteinases using compounds that are dibenzofuran sulfonamide derivatives having the Formula I More particularly, the present invention relates to a method of treating diseases in which matrix metalloproteinases are involved such as multiple sclerosis, atherosclerotic plaque rupture, restenosis, aortic aneurism, heart failure, periodontal disease, corneal ulceration, burns, decubital ulcers, chronic ulcers or wounds, cancer metastasis, tumor angiogenesis, arthritis, or other autoimmune or inflammatory diseases dependent upon tissue invasion by leukocytes.
摘要翻译：本发明涉及使用具有式I的二苯并呋喃磺酰胺衍生物的化合物抑制基质金属蛋白酶的方法。更具体地，本发明涉及治疗涉及基质金属蛋白酶的疾病的方法，例如多发性硬化，动脉粥样硬化斑块破裂，再狭窄，主动脉瘤，心力衰竭，牙周病，角膜溃疡，烧伤，褥疮性溃疡，慢性溃疡或创伤，癌转移，肿瘤血管生成，关节炎或依赖于白细胞组织侵袭的其他自身免疫性或炎性疾病。

10. 发明授权

US06620835B2 Method of inhibiting matrix metalloproteinases 失效
标题翻译：抑制基质金属蛋白酶的方法
公开(公告)号：US06620835B2
公开(公告)日：2003-09-16
申请号：US10162518
申请日：2002-06-04
申请人： Patrick Michael O'Brien , Joseph Armand Picard , Drago Robert Sliskovic , Andrew David White
发明人： Patrick Michael O'Brien , Joseph Armand Picard , Drago Robert Sliskovic , Andrew David White
IPC分类号： A61K31381
CPC分类号： C07D307/91 , A61K31/343 , A61K31/381 , C07C311/19 , C07C2603/18 , C07D333/76
摘要： The present invention relates to a method of inhibiting matrix metalloproteinases using compounds that are dibenzofuran sulfonamide derivatives having the Formula I More particularly, the present invention relates to a method of treating diseases in which matrix metalloproteinases are involved such as multiple sclerosis, atherosclerotic plaque rupture, restenosis, aortic aneurism, heart failure, periodontal disease, corneal ulceration, burns, decubital ulcers, chronic ulcers or wounds, cancer metastasis, tumor angiogenesis, arthritis, or other autoimmune or inflammatory diseases dependent upon tissue invasion by leukocytes.
摘要翻译：本发明涉及使用具有式IIIO的二苯并呋喃磺酰胺衍生物的化合物抑制基质金属蛋白酶的方法，本发明涉及治疗涉及基质金属蛋白酶的疾病的方法，例如多发性硬化，动脉粥样硬化斑块破裂，再狭窄，主动脉瘤，心力衰竭，牙周病，角膜溃疡，烧伤，褥疮性溃疡，慢性溃疡或创伤，癌症转移，肿瘤血管生成，关节炎或依赖于白细胞组织侵袭的其他自身免疫性或炎性疾病。

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