专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06831103B1 Composition comprising theanine 有权
标题翻译：组合物包含茶氨酸
公开(公告)号：US06831103B1
公开(公告)日：2004-12-14
申请号：US09655336
申请日：2000-09-05
申请人： Tomoko Ueda , Yukiko Nagato , Yukiko Tanaka , Tsutomu Okubo , Kanari Kobayashi , Nobuyuki Aoi , Seiji Shu , Lekh Raj Juneja
发明人： Tomoko Ueda , Yukiko Nagato , Yukiko Tanaka , Tsutomu Okubo , Kanari Kobayashi , Nobuyuki Aoi , Seiji Shu , Lekh Raj Juneja
IPC分类号： A61K31195
CPC分类号： A61K33/30 , A23L2/38 , A23L33/10 , A23L33/105 , A23L33/16 , A23L33/17 , A23L33/18 , A61K31/195 , A61K31/198 , A61K31/27 , A61K33/00 , A61K33/06 , A61K33/26 , A61K36/82 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a composition for suppressing or ameliorating a symptom accompanying diminished homeostasis, comprising theanine; and a mineral composition comprising theanine and a mineral. According to the present invention, there can be provided a composition for suppressing or ameliorating the above symptoms; and a mineral composition having a reduced peculiar metal taste, of which administration is made easily.
摘要翻译：本发明涉及一种用于抑制或改善伴随减少的体内平衡的症状的组合物，其包含茶氨酸; 以及包含茶氨酸和矿物质的矿物组合物。根据本发明，可以提供抑制或改善上述症状的组合物，和具有降低的特殊金属味道的矿物组合物，其容易施用。

2. 发明授权

US06797729B1 Therapeutic glutamine and N-actyl-cysteine composition 失效
标题翻译：治疗性谷氨酰胺和N-肌动蛋白半胱氨酸组合物
公开(公告)号：US06797729B1
公开(公告)日：2004-09-28
申请号：US08884170
申请日：1997-06-27
申请人： Theresa A. Byrne , Joanne A. Somerville
发明人： Theresa A. Byrne , Joanne A. Somerville
IPC分类号： A61K31195
CPC分类号： A61K31/015 , A61K31/195 , A61K31/34 , A61K31/35 , A61K2300/00
摘要： Compositions comprising glutamine in combination with other ingredients such as N-acetyl-cysteine are disclosed. Such compositions can be administered to treat patients with certain conditions of the body.
摘要翻译：公开了包含与其他成分如N-乙酰基 - 半胱氨酸组合的谷氨酰胺的组合物。可以施用这样的组合物以治疗患有身体某些状况的患者。

3. 发明授权

US06706763B1 O-anisamide derivatives 失效
标题翻译： O-茴香酰胺衍生物
公开(公告)号：US06706763B1
公开(公告)日：2004-03-16
申请号：US10070425
申请日：2002-03-18
申请人： Hiroya Satoh , Masakatsu Komuro , Koji Murakami , Katsuya Awano
发明人： Hiroya Satoh , Masakatsu Komuro , Koji Murakami , Katsuya Awano
IPC分类号： A61K31195
CPC分类号： C07C317/46 , C07C235/60 , C07C323/60
摘要： O-anisamide compounds and their addition salts effective for the prevention and/or therapy of metabolic diseases such as hyperlipidemia and diabetes, in which peroxisome proliferator-activated receptor (PPAR) being intranuclear receptor, in particular, human PPAR participates, as agonistic drugs thereon, and processes for preparing them, wherein the o-anisamide compounds are represented by a general formula (1) [wherein R denotes a carboxyl group, carboxymethyl group or CH2CHXCOY (here X denotes a mercapto group or S(O)nMe (n=0, 1 or 2) and Y denotes an amino group or hydroxyl group)], their medicinally acceptable salts, and their hydrates.
摘要翻译：作为其上的激动药物，有效用于预防和/或治疗代谢性疾病如高脂血症和糖尿病的O-茴香酰胺化合物及其加成盐，其中作为核内受体的过氧化物酶体增殖物激活受体（PPAR），特别是人PPAR参与其中及其制备方法，其中邻甲氧基苯甲酰胺化合物由通式（1）表示[其中R表示羧基，羧甲基或CH 2 CHXCOY（这里X表示巯基或S（O）nMe（n = 0,1或2），Y表示氨基或羟基）]，其药学上可接受的盐及其水合物。

4. 发明授权

US06685917B2 Treatment of mucositis 有权
公开(公告)号：US06685917B2
公开(公告)日：2004-02-03
申请号：US09993383
申请日：2001-11-21
申请人： Gary J. Rosenthal , Jeffrey B. Etter , Timothy C. Rodell , Wren H. Schauer , Adrian Samaniego
发明人： Gary J. Rosenthal , Jeffrey B. Etter , Timothy C. Rodell , Wren H. Schauer , Adrian Samaniego
IPC分类号： A61K31195
CPC分类号： A61K31/195 , A61K9/0014 , A61K9/006 , A61K9/06 , A61K31/198 , A61K47/10 , A61K47/34
摘要： This present invention provides a therapeutic composition for use in the treatment of mucositis and a method for using such a therapeutic composition. The therapeutic composition includes a pharmaceutical substance effective for treating mucositis formulated with a biocompatible polymer, such as a biocompatible reverse-thermal gelation polymer.

5. 发明授权

US06680343B1 Treatment of renal colic with GABA analogs 失效
标题翻译：用GABA类似物治疗肾绞痛
公开(公告)号：US06680343B1
公开(公告)日：2004-01-20
申请号：US09720007
申请日：2000-12-19
申请人： James T. Angello
发明人： James T. Angello
IPC分类号： A61K31195
CPC分类号： A61K31/195
摘要： The instant invention is a method of using certain analogs of glutamic acid and gamma-aminobutyric acid to relieve the pain associated with renal colic.
摘要翻译：本发明是使用谷氨酸和γ-氨基丁酸的某些类似物来减轻与肾绞痛相关的疼痛的方法。

6. 发明授权

US06599940B2 Synthesis of 2-hydroxymethylglutamic acid and congeners thereof 失效
标题翻译： 2-羟甲基谷氨酸及其同源物的合成
公开(公告)号：US06599940B2
公开(公告)日：2003-07-29
申请号：US09952325
申请日：2001-09-13
申请人： Alan P. Kozikowski
发明人： Alan P. Kozikowski
IPC分类号： A61K31195
CPC分类号： C07C229/24 , C07B2200/07 , C07D263/06
摘要： One aspect of the present invention relates to 2-hydroxymethylglutamic acid and congeners thereof. A second aspect of the invention relates to a method of synthesizing 2-hydroxymethylglutamic acid and congeners thereof.
摘要翻译：本发明的一个方面涉及2-羟甲基谷氨酸及其同源物。本发明的第二方面涉及合成2-羟甲基谷氨酸及其同源物的方法。

7. 发明授权

US06552070B2 Health food useful for preventing liver and biliary dysfunctions containing an alkanoyl L-carnitine and Silybum marianum extract 失效
标题翻译：用于预防含有链烷酰L-肉毒碱和水飞蓟马提取物的肝脏和胆汁功能障碍的保健食品
公开(公告)号：US06552070B2
公开(公告)日：2003-04-22
申请号：US10070160
申请日：2002-03-04
申请人： Pietro Pola
发明人： Pietro Pola
IPC分类号： A61K31195
CPC分类号： A61K36/28 , A23L33/10 , A23L33/105 , A23L33/15 , A23L33/175 , A23V2002/00 , Y10S514/893 , A61K2300/00 , A23V2250/708 , A23V2250/712 , A23V2250/718 , A23V2250/314 , A23V2250/0612 , A23V2250/21 , A23V2250/063 , A23V2250/0636 , A23V2250/0632 , A23V2250/304 , A23V2250/1626 , A23V2250/70 , A23V2250/0606 , A23V2250/30
摘要： A health food/dietary supplement is disclosed, endowed with a protective action on liver function against exogenous and endogenous hepatoxic agents, the characterizing components of which are isovaleryl L-carnitine and/or propionyl L-carnitine and an extract of Silybum marianum (milk thistle) standardized to a least 70 percent by weight of silymarin.
摘要翻译：披露了一种健康食品/膳食补充剂，对外源性和内源性肝毒素具有对肝功能的保护作用，其特征在于其组成为异戊酰L-肉毒碱和/或丙酰L-肉毒碱和水飞蓟属提取物（乳蓟）标准化至至少70％（重量）的水飞蓟素。

8. 发明授权

US06541521B1 Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases 失效
标题翻译：苯丁酸及其衍生物作为基质金属蛋白酶的抑制剂
公开(公告)号：US06541521B1
公开(公告)日：2003-04-01
申请号：US09351549
申请日：1999-07-12
申请人： Claude Forsey Purchase, Jr. , Bruce David Roth , Andrew David White
发明人： Claude Forsey Purchase, Jr. , Bruce David Roth , Andrew David White
IPC分类号： A61K31195
CPC分类号： C07D213/82 , C07C233/54 , C07C233/55 , C07C233/63 , C07C233/81 , C07C235/56 , C07C251/48 , C07C2601/14 , C07D333/38
摘要： Benzene butyric acid compounds and derivatives are described as well as methods for the preparation and pharmaceutical compositions of same, which are useful as inhibitors of matrix metalloproteinases, particularly gelatinase A, collagenase-3, and stromelysin-1 and for the treatment of multiple sclerosis, atherosclerotic plaque rupture, aortic aneurysm, heart failure, left ventricular dilation, restenosis, periodontal disease, corneal ulceration, treatment of burns, decubital ulcers, wound healing, cancer, inflammation, pain, arthritis, osteoporosis, renal disease, or other autoimmune or inflammatory disorders dependent upon tissue invasion by leukocytes or other activated migrating cells, acute and chronic neurodegenerative disorders including stroke, head trauma, spinal cord injury, Alzheimer's disease, amyotrophic lateral sclerosis, cerebral amyloid angiopathy, AIDS, Parkinson's disease, Huntington's disease, prion diseases, myasthenia gravis, and Duchenne's muscular dystrophy.
摘要翻译：苯丁酸化合物和衍生物以及其制备方法及其药物组合物的描述，其可用作基质金属蛋白酶抑制剂，特别是明胶酶A，胶原酶-3和溶基质溶解素-1以及用于治疗多发性硬化，动脉粥样硬化斑块破裂，主动脉瘤，心力衰竭，左心室扩张，再狭窄，牙周病，角膜溃疡，烧伤治疗，褥疮溃疡，伤口愈合，癌症，炎症，疼痛，关节炎，骨质疏松症，肾脏疾病或其他自身免疫或炎症依赖于白细胞或其他激活的迁移细胞的组织侵袭的疾病，急性和慢性神经变性疾病，包括中风，头部创伤，脊髓损伤，阿尔茨海默病，肌萎缩性侧索硬化，脑淀粉样血管病，艾滋病，帕金森病，亨廷顿病，朊病毒疾病，重症肌无力和Duchenne肌营养不良症。

9. 发明授权

US06534544B1 Methods of treatment with compounds having RAR&agr; receptor specific or selective activity 失效
标题翻译：用具有RARα受体特异性或选择性活性的化合物治疗的方法
公开(公告)号：US06534544B1
公开(公告)日：2003-03-18
申请号：US09350310
申请日：1999-07-09
申请人： Min Teng , Tien T. Duong , Roshantha A. Chandraratna
发明人： Min Teng , Tien T. Duong , Roshantha A. Chandraratna
IPC分类号： A61K31195
CPC分类号： A61K31/353 , A61K31/203 , A61K31/44 , G01N25/4866
摘要： Retinoid compounds which act specifically or selectively on RAR&agr; receptor subtypes in preference over RAR&bgr; and RAR&Ggr; receptor subtypes, possess desirable pharmaceutical properties associated with retinoids, and are particularly suitable for treatment of tumors, such as acute monocytic leukemia, cervical carcinoma, myeloma, ovarian carcinomas and head and neck carcinomas, without having one or more undesirable side effects of retinoids, such as inducement of weight loss, mucocutaneous toxicity, skin irritation and teratogenecity.
摘要翻译：与RARbeta和RARGAMMA受体亚型相比，RARα受体亚型特异性或选择性地起作用的类视黄醇化合物具有与类视黄醇相关的理想药物特性，特别适用于治疗肿瘤，如急性单核细胞白血病，宫颈癌，骨髓瘤，卵巢癌和头颈部癌，而不具有类维生素A的一种或多种不期望的副作用，例如诱导体重减轻，皮肤粘膜毒性，皮肤刺激和致畸性。

10. 发明授权

US06531510B1 N,N′-bis(2-hydroxybenzyl)ethylenediamine-N,N′-diacetic acid in iron chelating therapy 有权
标题翻译： N，N'-双（2-羟基苄基）乙二胺-N，N'-二乙酸铁螯合疗法
公开(公告)号：US06531510B1
公开(公告)日：2003-03-11
申请号：US09724823
申请日：2000-11-28
申请人： Raymond J. Bergeron, Jr.
发明人： Raymond J. Bergeron, Jr.
IPC分类号： A61K31195
CPC分类号： A61K31/195 , A61K31/198 , Y02A50/411
摘要： The use of a novel mono-cationic salt of N,N′-bis(2-hydroxybenzyl) ethylenediamine-N,N′-diacetic acid (HBED) in iron chelating therapy is disclosed. In particular, the invention relates to the subcutaneous use of a mono cationic salt of HBED for treating a human with a disease treatable by an iron chelator such as iron overload, especially transfusional iron overload.
摘要翻译：公开了在铁螯合治疗中使用N，N'-双（2-羟基苄基）乙二胺-N，N'-二乙酸（HBED）的新型单阳离子盐。特别地，本发明涉及HBED的单阳离子盐的皮下使用，用于治疗具有铁螯合剂可治疗的疾病的人，例如铁过载，特别是输血铁过载。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式