专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20090275600A1 MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS 有权
标题翻译：改性吡咯烷胆固醇受体调节剂
公开(公告)号：US20090275600A1
公开(公告)日：2009-11-05
申请号：US12499753
申请日：2009-07-08
申请人： Robin D. Clark , Nicolas C. Ray , Karen Williams , Peter H. Cracket , Gwen Hickin , David A. Clark
发明人： Robin D. Clark , Nicolas C. Ray , Karen Williams , Peter H. Cracket , Gwen Hickin , David A. Clark
IPC分类号： A61K31/506 , A61P25/18
CPC分类号： C07D239/545 , A61K31/506 , A61K31/513 , A61K31/551 , C07D401/04 , C07D403/04
摘要： The present invention provides a novel class of modified pyrimidine compounds and compositions and methods of using the compounds as glucocorticoid receptor modulators.
摘要翻译：本发明提供了一类新颖的改良嘧啶化合物及其组合物和使用该化合物作为糖皮质激素受体调节剂的方法。

2. 发明授权

US07576076B2 Modified pyrimidine glucocorticoid receptor modulators 有权
标题翻译：改性嘧啶糖皮质激素受体调节剂
公开(公告)号：US07576076B2
公开(公告)日：2009-08-18
申请号：US11174096
申请日：2005-06-29
申请人： Robin D. Clark , Nicolas C. Ray , Karen Williams , Peter H. Crackett , Gwen Hickin , David A. Clark
发明人： Robin D. Clark , Nicolas C. Ray , Karen Williams , Peter H. Crackett , Gwen Hickin , David A. Clark
IPC分类号： A01N43/62 , A61K31/50 , A61K31/497 , A61K31/501 , A61K31/505 , C07D403/00 , C07D401/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00 , C07D243/08
CPC分类号： C07D239/545 , A61K31/506 , A61K31/513 , A61K31/551 , C07D401/04 , C07D403/04
摘要： The present invention provides a compound having the formula: wherein, n and m are 1; X1 and X2 are O; R1 is a member selected from unsubstituted phenyl and substituted phenyl; R2 is a member selected from hydrogen, —CN, —OR2A, -L2A—C(O)R2B, -L2B—S(O)2R2C; R3 is a member selected from unsubstituted benzyl and substituted benzyl; R4 is a member selected from hydrogen and substituted or unsubstituted alkyl, wherein if R4 is methyl, then -L1-R1 is not benzyl or —C(O)—O—CH2—CH3; and L1 is a bond; and compositions and methods of using the compounds as glucocorticoid receptor modulators.
摘要翻译：本发明提供具有下式的化合物：其中n和m为1; X1和X2为O; R1是选自未取代的苯基和取代的苯基的成员; R2是选自氢，-CN，-OR2A，-L2A-C（O）R2B，-L2B-S（O）2R2C; R3是选自未取代的苄基和取代的苄基的成员; R4是选自氢和取代或未取代的烷基的成员，其中如果R 4是甲基，则-L 1 -R 1不是苄基或-C（O）-O-CH 2 -CH 3; 而L1是一个键; 以及使用该化合物作为糖皮质激素受体调节剂的组合物和方法。

3. 发明授权

US08173664B2 Modified pyrimidine glucocorticoid receptor modulators 有权
标题翻译：改性嘧啶糖皮质激素受体调节剂
公开(公告)号：US08173664B2
公开(公告)日：2012-05-08
申请号：US12499753
申请日：2009-07-08
申请人： Robin D. Clark , Nicolas C. Ray , Karen Williams , Peter H. Crackett , Gwen Hickin , David A. Clark
发明人： Robin D. Clark , Nicolas C. Ray , Karen Williams , Peter H. Crackett , Gwen Hickin , David A. Clark
IPC分类号： A01N43/54 , A61K31/505
CPC分类号： C07D239/545 , A61K31/506 , A61K31/513 , A61K31/551 , C07D401/04 , C07D403/04
摘要： The present invention provides a class of modified pyrimidine compounds, compositions and methods of using the compounds as glucocorticoid receptor modulators.
摘要翻译：本发明提供一类修饰的嘧啶化合物，使用该化合物作为糖皮质激素受体调节剂的组合物和方法。

4. 发明申请

US20120017707A1 SYSTEMS AND METHODS FOR DETECTING OBJECTS IN THE GROUND 审中-公开
标题翻译：用于检测地面物体的系统和方法
公开(公告)号：US20120017707A1
公开(公告)日：2012-01-26
申请号：US13011577
申请日：2011-01-21
申请人： Ronald Scott Jackson , David W. Simmons , David A. Clark
发明人： Ronald Scott Jackson , David W. Simmons , David A. Clark
IPC分类号： G01D21/00
CPC分类号： G01V3/15 , F41H11/136
摘要： The presently disclosed systems and methods may be utilized in connection with several different sensor suites for detecting objects in the ground. Such systems and methods may be utilized in conjunction with a variety of military and commercial vehicles. In various embodiments, a sensing system may be carried by a vehicle in a stowed or deployed position. While in the stowed position, a segmented boom may have a relatively small vertical profile in comparison to the length of the boom when fully extended. According to various embodiments, in the deployed position the height of the sensor may be controlled to avoid obstructions. A hoist connected to the boom may be utilized to move the boom between the deployed and stowed positions.
摘要翻译：目前公开的系统和方法可以结合用于检测地面中的物体的几个不同的传感器套件来使用。这种系统和方法可以与各种军用和商业车辆结合使用。在各种实施例中，感测系统可由车辆在收起或展开位置承载。在收起位置时，与完全伸展的吊杆长度相比，分段式起重臂可具有相对小的垂直轮廓。根据各种实施例，在展开位置中，可以控制传感器的高度以避免障碍物。可以使用连接到起重臂的起重机来将升降臂移动到展开位置和收起位置之间。

5. 发明授权

US08054819B2 System and method for setting a data rate in TDMA communications 有权
标题翻译：用于在TDMA通信中设置数据速率的系统和方法
公开(公告)号：US08054819B2
公开(公告)日：2011-11-08
申请号：US11951498
申请日：2007-12-06
申请人： Mark W. Chamberlain , David A. Clark , Joseph Shaver , John W. Nieto
发明人： Mark W. Chamberlain , David A. Clark , Joseph Shaver , John W. Nieto
IPC分类号： H04B7/212
CPC分类号： H04L1/0002 , H04L1/0019 , H04L1/20 , H04L2001/0092 , Y02D50/10
摘要： A mobile ad-hoc network includes a plurality of N mobile nodes and wireless communication links connecting the mobile nodes, which each include a communications device for transmitting and routing data packets wirelessly to other mobile nodes via the wireless communication links in accordance with a time division multiple access (TDMA) data transmission protocol using a TDMA epoch that is divided into a beacon interval, digital voice interval and digital data interval. The mobile nodes monitor channel conditions using the beacon, digital voice and digital data intervals and provide a network conductivity performance as valid receptions occur within mobile nodes. A data rate is calculated and set for other N−1 mobile nodes using monitored channel conditions for the beacon, digital voice and digital data intervals.
摘要翻译：移动自组织网络包括多个N个移动节点和连接移动节点的无线通信链路，每个移动节点包括用于根据时分经由无线通信链路无线地将数据分组无线地传送到其他移动节点的通信设备使用被划分为信标间隔，数字语音间隔和数字数据间隔的TDMA纪元的多址（TDMA）数据传输协议。移动节点使用信标，数字语音和数字数据间隔监视信道条件，并提供网络电导性能，因为在移动节点内发生有效的接收。使用信标，数字语音和数字数据间隔的监视信道条件，为其他N-1移动节点计算数据速率并设置数据速率。

6. 发明申请

US20090147766A1 SYSTEM AND METHOD FOR SETTING A DATA RATE IN TDMA COMMUNICATIONS 有权
标题翻译：用于设置TDMA通信中的数据速率的系统和方法
公开(公告)号：US20090147766A1
公开(公告)日：2009-06-11
申请号：US11951498
申请日：2007-12-06
申请人： Mark W. CHAMBERLAIN , David A. Clark , Joseph Shaver , John W. Nieto
发明人： Mark W. CHAMBERLAIN , David A. Clark , Joseph Shaver , John W. Nieto
IPC分类号： H04B7/212
CPC分类号： H04L1/0002 , H04L1/0019 , H04L1/20 , H04L2001/0092 , Y02D50/10
摘要： A mobile ad-hoc network includes a plurality of N mobile nodes and wireless communication links connecting the mobile nodes, which each include a communications device for transmitting and routing data packets wirelessly to other mobile nodes via the wireless communication links in accordance with a time division multiple access (TDMA) data transmission protocol using a TDMA epoch that is divided into a beacon interval, digital voice interval and digital data interval. The mobile nodes monitor channel conditions using the beacon, digital voice and digital data intervals and provide a network conductivity performance as valid receptions occur within mobile nodes. A data rate is calculated and set for other N−1 mobile nodes using monitored channel conditions for the beacon, digital voice and digital data intervals.
摘要翻译：移动自组织网络包括多个N个移动节点和连接移动节点的无线通信链路，每个移动节点包括用于根据时分经由无线通信链路无线地将数据分组无线地传送到其他移动节点的通信设备使用被划分为信标间隔，数字语音间隔和数字数据间隔的TDMA纪元的多址（TDMA）数据传输协议。移动节点使用信标，数字语音和数字数据间隔监视信道条件，并提供网络电导性能，因为在移动节点内发生有效的接收。使用信标，数字语音和数字数据间隔的监视信道条件，为其他N-1移动节点计算数据速率并设置数据速率。

7. 发明授权

US06749854B2 Use of OX-2 to inhibit fetal loss 失效
标题翻译：使用OX-2抑制胎儿的损失
公开(公告)号：US06749854B2
公开(公告)日：2004-06-15
申请号：US09934634
申请日：2001-08-23
申请人： Reginald M. Gorczynski , David A. Clark
发明人： Reginald M. Gorczynski , David A. Clark
IPC分类号： A61K3816
CPC分类号： C07K14/70503 , A61K38/00 , A61K48/00 , C07K16/2803 , C07K2319/00 , C07K2319/30 , Y10S514/885 , Y10S514/903
摘要： Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of an OX-2 protein or a nucleic acid encoding an OX-2 protein. The methods are useful in preventing graft rejection, fetal loss, autoimmune disease, and allergies. Methods and compositions for preventing immune suppression are also disclosed. The methods involve administering an effective amount of an agent that inhibits OX-2.
摘要翻译：公开了诱导免疫抑制的方法和组合物。所述方法包括施用有效量的OX-2蛋白或编码OX-2蛋白的核酸。该方法可用于预防移植物排斥，胎儿丧失，自身免疫性疾病和过敏。还公开了用于预防免疫抑制的方法和组合物。所述方法包括施用有效量的抑制OX-2的药剂。

8. 外观设计

USD479923S1 Buffet 失效
公开(公告)号：USD479923S1
公开(公告)日：2003-09-30
申请号：US29143045
申请日：2001-06-06
申请人： Richard D. Berry, Jr. , David A. Clark
设计人： Richard D. Berry, Jr. , David A. Clark

9. 发明授权

US5977501A Sortation and sequencing system 失效
标题翻译：分拣和排序系统
公开(公告)号：US5977501A
公开(公告)日：1999-11-02
申请号：US764950
申请日：1996-12-13
申请人： James Werkheiser , Phillip N. Ross , David A. Clark , Robert Porter
发明人： James Werkheiser , Phillip N. Ross , David A. Clark , Robert Porter
IPC分类号： B07C3/02 , B07C209/583
CPC分类号： B07C3/02 , Y10S209/917 , Y10S209/923 , Y10S209/942
摘要： A sortation and sequencing system for sorting a plurality of different items into discrete orders and putting the items into a predetermined sequence within each discrete order or group of orders. The system includes an induction station for accepting items in random succession, and a sensor at the induction station for sensing an identifying characteristic unique to each item and for generating tracking signals uniquely corresponding to the items for tracking the items through the system. A controller receives the tracking signals and generates sort command and sequence command signals which are in part responsive to the tracking signals. A sorter receives the items from the induction station and directs individual items to selected ones of a plurality of sort locations, each sort location corresponding to an individual order or group of orders, in response to sort command signals from the controller. A sequencer associated with each sort location receives sorted items from the sorter and discharges the items in a preselected sequence at a discharge location in response to the sequence control signals.
摘要翻译：一种分类和排序系统，用于将多个不同的项目分类成离散的订单，并将物品放入每个离散的订单或订单组中的预定顺序。该系统包括用于随机连续接收物品的感应台和感应台处的传感器，用于感测每个物品独有的识别特征，并产生唯一对应于通过系统跟踪物品的物品的跟踪信号。控制器接收跟踪信号并产生分类命令和序列命令信号，其部分地响应跟踪信号。分类器响应于来自控制器的分类命令信号，从各导入站接收项目，并将各个项目引导到多个分类位置中的选定的分类位置，每个分类位置对应于单个顺序或一组订单。与每个分类位置相关联的定序器响应于序列控制信号，从分类器接收排序的物品，并以放电位置的预选序列排出物品。

10. 发明授权

US5915387A Cigarette for electrical smoking system 失效
公开(公告)号：US5915387A
公开(公告)日：1999-06-29
申请号：US777827
申请日：1996-12-31
申请人： James D. Baggett, Jr. , David A. Clark , Mary Ellen Counts , Patrick C. Cowling , Willie G. Houck, Jr. , Michael A. Moore , Wesley G. Sanderson , Richard G. Uhl , Michael L. Watkins , Susan E. Wrenn
发明人： James D. Baggett, Jr. , David A. Clark , Mary Ellen Counts , Patrick C. Cowling , Willie G. Houck, Jr. , Michael A. Moore , Wesley G. Sanderson , Richard G. Uhl , Michael L. Watkins , Susan E. Wrenn
IPC分类号： A24F47/00 , A24F1/28
CPC分类号： A24F47/008
摘要： A novel cigarette adapted for use in an electrical cigarette system comprising a tobacco rod having filled and unfilled tobacco rod portions and being arranged so that electrical heater elements may overlap the filled and unfilled tobacco rod portions. The tobacco rod includes a tobacco web rolled into tubular form. The tobacco web is constructed in accordance with a novel process comprising the steps of converting tobacco feedstock into a continuous sheet of tobacco web and converting the continuous sheet of tobacco web into one or more bobbins of tobacco web suitable for automated manufacture of cigarettes.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式