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1. 发明申请

US20060036317A1 Decives and methods for heart valve treatment 有权
标题翻译：心脏瓣膜治疗的方法和方法
公开(公告)号：US20060036317A1
公开(公告)日：2006-02-16
申请号：US11175270
申请日：2005-07-07
申请人： Robert Vidlund , Cyril Schweich , Todd Mortier , Richard Schroeder , Craig Ekvall , Jason Kalgreen , Edward Matthees , David Kusz
发明人： Robert Vidlund , Cyril Schweich , Todd Mortier , Richard Schroeder , Craig Ekvall , Jason Kalgreen , Edward Matthees , David Kusz
IPC分类号： A61F2/24
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/04 , A61B17/1325 , A61B17/32053 , A61B2017/00243 , A61B2017/0404 , A61B2017/0412 , A61B2017/0464 , A61B2017/0496 , A61F2/2442 , Y10S623/904
摘要： Devices and methods for improving the function of a valve (e.g., mitral valve) by positioning a spacing filling device outside and adjacent the heart wall such that the device applies an inward force against the heart wall acting on the valve. A substantially equal and opposite force may be provided by securing the device to the heart wall, and/or a substantially equal and opposite outward force may be applied against anatomical structure outside the heart wall. The inward force is sufficient to change the function of the valve, and may increase coaptation of the leaflets, for example. The space filling device may be implanted by a surgical approach, a transthoracic approach, or a transluminal approach, for example. The space filling portion may be delivered utilizing a delivery catheter navigated via the selected approach, and the space filling portion may be expandable between a smaller delivery configuration and a larger deployed configuration.
摘要翻译：通过将间隔填充装置定位在心壁周围和邻近心壁的位置使得该装置向作用在瓣膜上的心壁施加向内的力来改善瓣膜（例如二尖瓣）的功能的装置和方法。可以通过将装置固定到心脏壁来提供基本上相等且相反的力，和/或可以对心壁外部的解剖结构施加基本上相等且相反的向外的力。向内的力足以改变阀的功能，并且例如可以增加传单的接合。空间填充装置可以通过例如外科手术，经胸腔手术或经腔手术植入。空间填充部分可以利用经由所选择的方法导航的递送导管来传送，空间填充部分可以在较小的传送配置和更大的部署配置之间扩展。

2. 发明申请

US20070050022A1 Devices and methods for heart valve treatment 审中-公开
标题翻译：心脏瓣膜治疗的装置和方法
公开(公告)号：US20070050022A1
公开(公告)日：2007-03-01
申请号：US11451354
申请日：2006-06-13
申请人： Robert Vidlund , Jason Kalgreen , Todd Mortier , Cyril Schweich , Richard Schroeder , David Kusz
发明人： Robert Vidlund , Jason Kalgreen , Todd Mortier , Cyril Schweich , Richard Schroeder , David Kusz
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B2017/00243 , A61B2017/0417 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052 , A61F2/2445 , A61F2/2454 , A61F2/246 , A61F2/2481 , A61F2/2487
摘要： Devices and methods for treating heart valves include members that assist the valve in closing during at least a portion of the cardiac cycle. Such devices include members configured to alter the shape of a valve annulus, reposition at least one papillary muscle, and/or plug an orifice of the valve so as to provide a coaptation surface for the valve leaflets.
摘要翻译：用于治疗心脏瓣膜的装置和方法包括在心脏周期的至少一部分期间辅助阀关闭的构件。这样的装置包括构造成改变瓣膜环的形状，重新定位至少一个乳头状肌肉和/或堵塞瓣膜的孔的构件，以便提供瓣膜小叶的接合表面。

3. 发明申请

US20060041306A1 Devices and methods for heart valve treatment 有权
公开(公告)号：US20060041306A1
公开(公告)日：2006-02-23
申请号：US11171677
申请日：2005-07-01
申请人： Robert Vidlund , Jason Kalgreen , Todd Mortier , Cyril Schweich , Richard Schroeder , David Kusz
发明人： Robert Vidlund , Jason Kalgreen , Todd Mortier , Cyril Schweich , Richard Schroeder , David Kusz
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B2017/00243 , A61B2017/0417 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052 , A61F2/2445 , A61F2/2454 , A61F2/246 , A61F2/2481 , A61F2/2487
摘要： Devices and methods for treating heart valves include members that assist the valve in closing during at least a portion of the cardiac cycle. Such devices include members configured to alter the shape of a valve annulus, reposition at least one papillary muscle, and/or plug an orifice of the valve so as to provide a coaptation surface for the valve leaflets.

4. 发明申请

US20060241340A1 Methods and devices for improving mitral valve function 有权
公开(公告)号：US20060241340A1
公开(公告)日：2006-10-26
申请号：US11404093
申请日：2006-04-14
申请人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich , Todd Mortier , Marc Simmon , Peter Keith
发明人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich , Todd Mortier , Marc Simmon , Peter Keith
IPC分类号： A61F2/02
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/1227 , A61B2017/00243 , A61B2017/0404 , A61B2017/048 , A61B2017/0496 , A61F2/2481
摘要： The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber. Also described herein is a method for placing a splint assembly transverse a heart chamber by advancing an elongate member through vasculature structure and into the heart chamber.

5. 发明授权

US07766812B2 Methods and devices for improving mitral valve function 有权
标题翻译：改善二尖瓣功能的方法和装置
公开(公告)号：US07766812B2
公开(公告)日：2010-08-03
申请号：US11404093
申请日：2006-04-14
申请人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich, Jr. , Todd Mortier , Marc Simmon , Peter Keith
发明人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich, Jr. , Todd Mortier , Marc Simmon , Peter Keith
IPC分类号： A61M1/10
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/1227 , A61B2017/00243 , A61B2017/0404 , A61B2017/048 , A61B2017/0496 , A61F2/2481
摘要： The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber. Also described herein is a method for placing a splint assembly transverse a heart chamber by advancing an elongate member through vasculature structure and into the heart chamber.
摘要翻译：本发明的各个方面涉及用于治疗心脏病症的装置和相关方法，包括例如扩张，瓣膜无能力，包括二尖瓣渗漏和其它类似的心力衰竭病症。本发明的装置和相关方法用于协助心脏瓣膜小叶的安置以改善瓣膜功能。根据本发明的一个方面，一种方法通过将细长构件横向放置在心室中来改善心脏瓣膜的功能，使得细长构件的每个端部延伸穿过心脏的壁，并且将第一和第二锚定会员外部室。第一和第二锚固构件附接到细长构件的第一和第二端部，以将细长构件固定在穿过腔室的位置，以便重新定位腔室内的乳头肌肉。本文还描述了通过使细长构件通过脉管系统结构并进入心脏腔室来放置夹板组件横向于心室的方法。

6. 发明授权

US09198757B2 Methods and devices for improving mitral valve function 有权
标题翻译：改善二尖瓣功能的方法和装置
公开(公告)号：US09198757B2
公开(公告)日：2015-12-01
申请号：US12498956
申请日：2009-07-07
申请人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich, Jr. , Todd Mortier , Marc Simmon , Peter Keith
发明人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich, Jr. , Todd Mortier , Marc Simmon , Peter Keith
IPC分类号： A61B1/00 , A61F2/24 , A61B17/00 , A61B17/122 , A61B17/04
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/1227 , A61B2017/00243 , A61B2017/0404 , A61B2017/048 , A61B2017/0496 , A61F2/2481
摘要： The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber. Also described herein is a method for placing a splint assembly transverse a heart chamber by advancing an elongate member through vasculature structure and into the heart chamber.
摘要翻译：本发明的各个方面涉及用于治疗心脏病症的装置和相关方法，包括例如扩张，瓣膜无能力，包括二尖瓣渗漏和其它类似的心力衰竭病症。本发明的装置和相关方法用于协助心脏瓣膜小叶的安置以改善瓣膜功能。根据本发明的一个方面，一种方法通过将细长构件横向放置在心室中来改善心脏瓣膜的功能，使得细长构件的每个端部延伸穿过心脏的壁，并且将第一和第二锚定会员外部室。第一和第二锚固构件附接到细长构件的第一和第二端部，以将细长构件固定在穿过腔室的位置，以便重新定位腔室内的乳头肌肉。本文还描述了通过使细长构件通过脉管系统结构并进入心脏腔室来放置夹板组件横向于心室的方法。

7. 发明申请

US20070055303A1 Endovascular splinting devices and methods 审中-公开
标题翻译：血管内夹板装置及方法
公开(公告)号：US20070055303A1
公开(公告)日：2007-03-08
申请号：US11543892
申请日：2006-10-06
申请人： Robert Vidlund , Marc Simmon , Todd Mortier , Cyril Schweich , Peter Keith , Richard Schroeder , Jason Kalgreen
发明人： Robert Vidlund , Marc Simmon , Todd Mortier , Cyril Schweich , Peter Keith , Richard Schroeder , Jason Kalgreen
IPC分类号： A61B17/08
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/064 , A61B17/0682 , A61B90/39 , A61B2017/00243 , A61B2017/003 , A61B2017/00557 , A61B2017/00907 , A61B2017/0404 , A61B2017/0409 , A61B2017/0412 , A61B2017/0437 , A61B2017/0464 , A61B2017/048 , A61B2017/0496
摘要： A method for placing a splint assembly transverse a heart chamber includes providing an elongate member having a first end and a second end and a deployable heart-engaging assembly connected to at least the first end. The method includes advancing the elongate member through vasculature structure and into the heart chamber such that the first end of the elongate member extends through a first location of a wall surrounding the heart chamber and the second end extends through a second location of the heart chamber wall substantially opposite the first location. A deployable heart-engaging assembly is deployed such that it engages with a first exterior surface portion of the heart chamber wall adjacent the first location. The elongate member is secured with respect to the heart with a second heart-engaging assembly connected to the second end. The second heart-engaging assembly engages with a second exterior surface portion of the heart chamber wall adjacent the second location. A splint assembly includes an expandable heart-engaging assembly formed partially from portions forming the elongate member of the splint assembly. A delivery tool includes a tubular member configured to be advanced through vasculature structure and has a curved distal end.
摘要翻译：用于将夹板组件放置在心室上的方法包括提供具有第一端和第二端的细长构件以及连接到至少第一端的可展开的心脏接合组件。该方法包括使细长构件通过脉管系统结构推进并进入心室，使得细长构件的第一端延伸穿过围绕心室的壁的第一位置，并且第二端延伸通过心室壁的第二位置基本上与第一位置相对。展开的心脏接合组件被布置成使得其与邻近第一位置的心室壁的第一外表面部分接合。细长构件相对于心脏固定，第二心脏接合组件连接到第二端。第二心脏接合组件与邻近第二位置的心室壁的第二外表面部分接合。夹板组件包括可部分地由形成夹板组件的细长构件的部分形成的可膨胀心脏接合组件。输送工具包括构造成通过脉管系统结构前进并具有弯曲远端的管状构件。

8. 发明申请

US20050075723A1 Methods and devices for improving mitral valve function 审中-公开
标题翻译：改善二尖瓣功能的方法和装置
公开(公告)号：US20050075723A1
公开(公告)日：2005-04-07
申请号：US10840511
申请日：2004-05-07
申请人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich , Todd Mortier , Marc Simmon , Peter Keith
发明人： Richard Schroeder , Robert Vidlund , Jason Kalgreen , Cyril Schweich , Todd Mortier , Marc Simmon , Peter Keith
IPC分类号： A61B17/00 , A61B17/04 , A61B17/122 , A61F2/04 , A61F2/24
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/1227 , A61B2017/00243 , A61B2017/0404 , A61B2017/048 , A61B2017/0496 , A61F2/2481
摘要： The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber. Also described herein is a method for placing a splint assembly transverse a heart chamber by advancing an elongate member through vasculature structure and into the heart chamber.
摘要翻译：本发明的各个方面涉及用于治疗心脏病症的装置和相关方法，包括例如扩张，瓣膜无能力，包括二尖瓣渗漏和其它类似的心力衰竭病症。本发明的装置和相关方法用于协助心脏瓣膜小叶的安置以改善瓣膜功能。根据本发明的一个方面，一种方法通过将细长构件横向放置在心室中来改善心脏瓣膜的功能，使得细长构件的每个端部延伸穿过心脏的壁，并且将第一和第二锚定会员外部室。第一和第二锚固构件附接到细长构件的第一和第二端部，以将细长构件固定在穿过腔室的位置，以便重新定位腔室内的乳头肌肉。本文还描述了通过使细长构件通过脉管系统结构并进入心脏腔室来放置夹板组件横向于心室的方法。

9. 发明授权

US07112219B2 Devices and methods for heart valve treatment 有权
标题翻译：心脏瓣膜治疗的装置和方法
公开(公告)号：US07112219B2
公开(公告)日：2006-09-26
申请号：US10704143
申请日：2003-11-10
申请人： Robert M. Vidlund , Cyril J. Schweich, Jr. , Todd J. Mortier , Richard Schroeder , Craig Ekvall , Jason Kalgreen , Edward Matthees , David Kusz
发明人： Robert M. Vidlund , Cyril J. Schweich, Jr. , Todd J. Mortier , Richard Schroeder , Craig Ekvall , Jason Kalgreen , Edward Matthees , David Kusz
IPC分类号： A61F2/24
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/04 , A61B17/1325 , A61B17/32053 , A61B2017/00243 , A61B2017/0404 , A61B2017/0412 , A61B2017/0464 , A61B2017/0496 , A61F2/2442 , Y10S623/904
摘要： Devices and methods for improving the function of a valve (e.g., mitral valve) by positioning a spacing filling device outside and adjacent the heart wall such that the device applies an inward force against the heart wall acting on the valve. A substantially equal and opposite force may be provided by securing the device to the heart wall, and/or a substantially equal and opposite outward force may be applied against anatomical structure outside the heart wall. The inward force is sufficient to change the function of the valve, and may increase coaptation of the leaflets, for example. The space filling device may be implanted by a surgical approach, a transthoracic approach, or a transluminal approach, for example. The space filling portion may be delivered utilizing a delivery catheter navigated via the selected approach, and the space filling portion may be expandable between a smaller delivery configuration and a larger deployed configuration.
摘要翻译：通过将间隔填充装置定位在心壁周围和邻近心壁的位置使得该装置向作用在瓣膜上的心壁施加向内的力来改善瓣膜（例如二尖瓣）的功能的装置和方法。可以通过将装置固定到心脏壁来提供基本上相等且相反的力，和/或可以对心壁外部的解剖结构施加基本上相等且相反的向外的力。向内的力足以改变阀的功能，并且例如可以增加传单的接合。空间填充装置可以通过例如外科手术，经胸腔手术或经腔手术植入。空间填充部分可以利用经由所选择的方法导航的递送导管来传送，空间填充部分可以在较小的传送配置和更大的部署配置之间扩展。

10. 发明授权

US07666224B2 Devices and methods for heart valve treatment 有权
标题翻译：心脏瓣膜治疗的装置和方法
公开(公告)号：US07666224B2
公开(公告)日：2010-02-23
申请号：US11175270
申请日：2005-07-07
申请人： Robert M. Vidlund , Cyril J. Schweich, Jr. , Todd J. Mortier , Richard Schroeder , Craig Ekvall , Jason Kalgreen , Edward Matthees , David Kusz
发明人： Robert M. Vidlund , Cyril J. Schweich, Jr. , Todd J. Mortier , Richard Schroeder , Craig Ekvall , Jason Kalgreen , Edward Matthees , David Kusz
IPC分类号： A61F2/24
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/04 , A61B17/1325 , A61B17/32053 , A61B2017/00243 , A61B2017/0404 , A61B2017/0412 , A61B2017/0464 , A61B2017/0496 , A61F2/2442 , Y10S623/904
摘要： Devices and methods for improving the function of a valve (e.g., mitral valve) by positioning a spacing filling device outside and adjacent the heart wall such that the device applies an inward force against the heart wall acting on the valve. A substantially equal and opposite force may be provided by securing the device to the heart wall, and/or a substantially equal and opposite outward force may be applied against anatomical structure outside the heart wall. The inward force is sufficient to change the function of the valve, and may increase coaptation of the leaflets, for example. The space filling device may be implanted by a surgical approach, a transthoracic approach, or a transluminal approach, for example. The space filling portion may be delivered utilizing a delivery catheter navigated via the selected approach, and the space filling portion may be expandable between a smaller delivery configuration and a larger deployed configuration.
摘要翻译：通过将间隔填充装置定位在心壁周围和邻近心壁的位置使得该装置向作用在瓣膜上的心壁施加向内的力来改善瓣膜（例如二尖瓣）的功能的装置和方法。可以通过将装置固定到心脏壁来提供基本上相等且相反的力，和/或可以对心壁外部的解剖结构施加基本相等且相反的向外的力。向内的力足以改变阀的功能，并且例如可以增加传单的接合。空间填充装置可以通过例如外科手术，经胸腔手术或经腔手术植入。空间填充部分可以利用经由所选择的方法导航的递送导管来传送，空间填充部分可以在较小的传送配置和更大的部署配置之间扩展。

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