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1. 发明申请

US20050288600A1 Automatic orientation determination for ECG measurements using multiple electrodes 有权
标题翻译：使用多个电极的ECG测量的自动取向确定
公开(公告)号：US20050288600A1
公开(公告)日：2005-12-29
申请号：US10876008
申请日：2004-06-24
申请人： Yi Zhang , Marina Brockway , Carlos Ricci , Ron Heil , Douglas Daum , Robert Sweeney , Aaron McCabe
发明人： Yi Zhang , Marina Brockway , Carlos Ricci , Ron Heil , Douglas Daum , Robert Sweeney , Aaron McCabe
IPC分类号： A61B5/00 , A61B5/04 , A61B5/0402 , A61B5/042 , A61N1/365 , A61N1/375 , G06K9/62
CPC分类号： A61B5/0006 , A61B5/0031 , A61B5/04011 , A61B5/0422 , A61B5/7207 , A61B5/7217 , A61N1/3756 , G06K9/624
摘要： Cardiac monitoring and/or stimulation methods and systems provide monitoring, defibrillation and/or pacing therapies. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal using a source separation algorithm, and identifies a cardiac signal using a selected vector. The signal processor may iteratively separate signals from the plurality of composite signals until the cardiac signal is identified. The selected vector may be updated if desired or necessary. A method of signal separation involves detecting a plurality of composite signals at a plurality of locations, separating a signal using source separation, and selecting a vector that provides a cardiac signal. The separation may include a principal component analysis and/or an independent component analysis. Vectors may be selected and updated based on changes of position and/or orientation of implanted components and changes in patient parameters such as patient condition, cardiac signal-to-noise ratio, and disease progression.
摘要翻译：心脏监测和/或刺激方法和系统提供监测，除颤和/或起搏治疗。信号处理器接收与多个源相关联的多个复合信号，使用源分离算法分离信号，并使用所选择的向量来识别心脏信号。信号处理器可以迭代地分离来自多个复合信号的信号，直到识别出心脏信号。如果需要或必要，可以更新所选择的向量。信号分离的方法包括在多个位置检测多个复合信号，使用源分离分离信号，以及选择提供心脏信号的向量。分离可以包括主成分分析和/或独立成分分析。可以基于植入组件的位置和/或取向的改变以及患者参数（例如患者状况，心脏信噪比和疾病进展）的变化来选择和更新载体。

2. 发明申请

US20070203419A1 Tachyarrhythmia detection and discrimination based on curvature parameters 失效
标题翻译：基于曲率参数的快速性心律失常检测和鉴别
公开(公告)号：US20070203419A1
公开(公告)日：2007-08-30
申请号：US10607818
申请日：2003-06-27
申请人： Robert Sweeney , Carlos Ricci
发明人： Robert Sweeney , Carlos Ricci
IPC分类号： A61B5/04
CPC分类号： G06K9/00523 , A61B5/0245 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61B5/7264 , A61N1/362 , A61N1/3962
摘要： Estimating a frequency of a sampled cardiac rhythm signal and classifying the rhythm. The received signal is sampled and transformed into a curvature series. A lobe in the curvature series corresponds to a characteristic point in the sampled series. Characteristic points are selected based on a time of a lobe in the curvature series and, in one embodiment, an amplitude of the signal at the time of the lobe. A frequency of the sampled series is estimated by autocorrelating a function of the series of the characteristic points. In one embodiment, the function is a time difference function. The rhythm is classified by plotting the timewise proximity of characteristic points derived from an atrial signal with characteristic points derived from a ventricular signal. Regions of the plot are associated with a particular rhythm and the grouping of the data corresponds to the classification.
摘要翻译：估计采样心律信号的频率并对节律进行分类。接收到的信号被采样并转换成曲率系列。曲率系列中的凸角对应于采样系列中的特征点。基于曲率序列中的波瓣的时间选择特征点，并且在一个实施例中，选择在波瓣时的信号的幅度。通过自相关一系列特征点的函数来估计采样序列的频率。在一个实施例中，该功能是时差功能。通过绘制从心房信号得到的特征点与从心室信号得到的特征点的时间接近，分类节律。地块的区域与特定节奏相关联，数据分组对应于分类。

3. 发明申请

US20100121209A1 Arrhythmia Discrimination Based on Determination of Rate Dependency 审中-公开
标题翻译：基于速率依赖性确定的心律失常鉴别
公开(公告)号：US20100121209A1
公开(公告)日：2010-05-13
申请号：US12686122
申请日：2010-01-12
申请人： Shelley Cazares , Jaeho Kim , Yayun Lin , Carlos Ricci
发明人： Shelley Cazares , Jaeho Kim , Yayun Lin , Carlos Ricci
IPC分类号： A61B5/0464
CPC分类号： A61B5/0464 , A61B5/04525 , A61B5/7264
摘要： Cardiac systems and methods provide for discriminating between supraventricular tachyarrhythmia and ventricular tachyarrhythmia based on a determination that the patient's supraventricular rhythm exhibits rate dependency. One approach involves determining if a patient's supraventricular rhythm exhibits rate dependent morphology. If the patient's supraventricular rhythm is determined to exhibit rate dependent morphology, an implantable device classifies a detected tachyarrhythmia episode based on one or more templates selected from a plurality of rate-indexed templates stored in the device. Determining if the supraventricular rhythm exhibits rate dependent morphology may also include determining one or more rates at which the rate dependent morphology occurs.
摘要翻译：心脏系统和方法基于确定患者的室上节律表现出速率依赖性，确定了室上性快速性心律失常与室性快速性心律失常之间的区别。一种方法涉及确定患者的室上节律是否表现出速率依赖性形态。如果确定患者的室上节律表现出与速率相关的形态，则可植入装置基于从存储在装置中的多个速率索引模板中选择的一个或多个模板来分类检测到的快速性心律失常发作。确定室性心律显示出速率依赖性形态还可以包括确定发生速率依赖形态的一个或多个速率。

4. 发明申请

US20060200034A1 Apparatus for signal decomposition, analysis and reconstruction 有权
标题翻译：用于信号分解，分析和重构的装置
公开(公告)号：US20060200034A1
公开(公告)日：2006-09-07
申请号：US11360135
申请日：2006-02-23
申请人： Carlos Ricci , Vladimir Kovtun
发明人： Carlos Ricci , Vladimir Kovtun
IPC分类号： A61B5/04
CPC分类号： H03H17/0201 , A61B5/0006 , A61B5/04014 , A61B5/0432 , A61B5/044 , G06K9/00523
摘要： The present invention provides a system and method for representing quasi-periodic (“qp”) waveforms comprising, representing a plurality of limited decompositions of the qp waveform, wherein each decomposition includes a first and second amplitude value and at least one time value. In some embodiments, each of the decompositions is phase adjusted such that the arithmetic sum of the plurality of limited decompositions reconstructs the qp waveform. These decompositions are stored into a data structure having a plurality of attributes. Optionally, these attributes are used to reconstruct the qp waveform, or patterns or features of the qp wave can be determined by using various pattern-recognition techniques. Some embodiments provide a system that uses software, embedded hardware or firmware to carry out the above-described method. Some embodiments use a computer-readable medium to store the data structure and/or instructions to execute the method.
摘要翻译：本发明提供一种用于表示准周期（“qp”）波形的系统和方法，包括表示qp波形的多个有限分解，其中每个分解包括第一和第二振幅值和至少一个时间值。在一些实施例中，每个分解被相位调整，使得多个有限分解的算术和重建qp波形。这些分解被存储到具有多个属性的数据结构中。可选地，这些属性用于重建qp波形，或者可以通过使用各种模式识别技术来确定qp波的图案或特征。一些实施例提供使用软件，嵌入式硬件或固件来执行上述方法的系统。一些实施例使用计算机可读介质来存储用于执行该方法的数据结构和/或指令。

5. 发明授权

US07024240B2 Delay to therapy following patient controlled atrial shock therapy request 失效
公开(公告)号：US07024240B2
公开(公告)日：2006-04-04
申请号：US10643513
申请日：2003-08-19
申请人： Victor T. Chen , Gary T. Seim , Carlos Ricci , Michael L. Favet , Hal Propp
发明人： Victor T. Chen , Gary T. Seim , Carlos Ricci , Michael L. Favet , Hal Propp
IPC分类号： A61N1/39
CPC分类号： A61N1/3956
摘要： An implantable cardiac device detects a patient therapy request originating from external to the implantable device. A shock therapy delay period is timed in response to the detection of the patient therapy request. Atrial shock therapy is provided to the patient after expiration of the shock therapy delay period (if the presence of an ongoing atrial arrhythmia is detected). The patient therapy request may be provided by a patient activator including a magnet for operating a reed switch in the implanted device to provide the request. A patient activator including an input and receiver/transmitter circuitry may be employed to request the immediate providing of atrial shock therapy, and/or to set the duration the shock therapy delay period. By allowing specific delays to therapy after a therapy request, a patient can prepare for the requested therapy and thereby mitigate therapy discomfort.

6. 发明授权

US06618617B2 Delay to therapy following patient controlled atrial shock therapy request 有权
公开(公告)号：US06618617B2
公开(公告)日：2003-09-09
申请号：US09839123
申请日：2001-04-20
申请人： Victor T. Chen , Gary T. Seim , Carlos Ricci , Michael L. Favet , Hal Propp
发明人： Victor T. Chen , Gary T. Seim , Carlos Ricci , Michael L. Favet , Hal Propp
IPC分类号： A61N139
CPC分类号： A61N1/3956
摘要： An implantable cardiac device detects a patient therapy request originating from external to the implantable device. A shock therapy delay period is timed in response to the detection of the patient therapy request. Atrial shock therapy is provided to the patient after expiration of the shock therapy delay period (if the presence of an ongoing atrial arrhythmia is detected). The patient therapy request may be provided by a patient activator including a magnet for operating a reed switch in the implanted device to provide the request. A patient activator including an input and receiver/transmitter circuitry may be employed to request the immediate providing of atrial shock therapy, and/or to set the duration of the shock therapy delay period. By allowing specific delays to therapy after a therapy request, a patient can prepare for the requested therapy and thereby mitigate therapy discomfort.

7. 发明申请

US20100268293A1 DELAY TO THERAPY FOLLOWING PATIENT CONTROLLED ATRIAL SHOCK THERAPY REQUEST 失效
标题翻译：延迟治疗患者控制的急救措施
公开(公告)号：US20100268293A1
公开(公告)日：2010-10-21
申请号：US12828005
申请日：2010-06-30
申请人： Victor T. Chen , Gary T. Seim , Carlos Ricci , Michael L. Favet , Hal Propp
发明人： Victor T. Chen , Gary T. Seim , Carlos Ricci , Michael L. Favet , Hal Propp
IPC分类号： A61N1/39
CPC分类号： A61N1/3956
摘要： An implantable cardiac device detects a patient therapy request originating from external to the implantable device. A shock therapy delay period is timed in response to the detection of the patient therapy request. Atrial shock therapy is provided to the patient after expiration of the shock therapy delay period (if the presence of an ongoing atrial arrhythmia is detected). The patient therapy request may be provided by a patient activator including a magnet for operating a reed switch in the implanted device to provide the request. A patient activator including an input and receiver/transmitter circuitry may be employed to request the immediate providing of atrial shock therapy, and/or to set the duration the shock therapy delay period. By allowing specific delays to therapy after a therapy request, a patient can prepare for the requested therapy and thereby mitigate therapy discomfort.
摘要翻译：可植入心脏装置检测源自可植入装置外部的患者治疗请求。响应于患者治疗请求的检测，休克治疗延迟期是定时的。在休克治疗延迟期结束后（如果检测到正在进行的心律失常的存在），向患者提供心房休克疗法。患者治疗请求可以由患者激活器提供，包括用于在植入装置中操作舌簧开关的磁体以提供请求。可以使用包括输入和接收器/发射器电路的患者激活器来请求立即提供心房休克疗法和/或设置休克治疗延迟时期的持续时间。通过在治疗请求后允许特定的延迟治疗，患者可以准备所要求的治疗，从而减轻治疗不适。

8. 发明授权

US07668594B2 Method and apparatus for delivering chronic and post-ischemia cardiac therapies 失效
标题翻译：用于递送慢性和缺血后心脏治疗的方法和装置
公开(公告)号：US07668594B2
公开(公告)日：2010-02-23
申请号：US11207251
申请日：2005-08-19
申请人： Marina Brockway , Joseph M. Pastore , Yi Zhang , Carlos Ricci , Allan Shuros , Rodney W. Salo
发明人： Marina Brockway , Joseph M. Pastore , Yi Zhang , Carlos Ricci , Allan Shuros , Rodney W. Salo
IPC分类号： A61N1/368 , A61N1/08
CPC分类号： A61N1/36585 , A61N1/056 , A61N1/36114 , A61N1/3627 , A61N1/36521 , A61N1/36557
摘要： An implantable cardiac rhythm management (CRM) device delivers a chronic therapy while detecting an ischemic state. When the ischemic state indicates the occurrence of an ischemic event, the implantable CRM device delivers a post-ischemia therapy. The post-ischemia therapy and the chronic therapy are adjusted using feedback control with the ischemic state and parameters indicative of the effectiveness of the post-ischemic therapy and the effectiveness of the chronic therapy as inputs.
摘要翻译：植入式心律管理（CRM）装置在检测缺血状态时进行慢性治疗。当缺血状态表明发生缺血事件时，可植入的CRM装置传递缺血后的治疗。使用具有缺血状态的反馈控制和指示缺血后治疗的有效性和作为输入的慢性治疗的有效性的参数来调整局部后缺血治疗和慢性治疗。

9. 发明授权

US07467009B2 Cardiac rhythm management system with noise detector 有权
标题翻译：具有噪声检测器的心律管理系统
公开(公告)号：US07467009B2
公开(公告)日：2008-12-16
申请号：US11110490
申请日：2005-04-20
申请人： Surekha Palreddy , Carlos Ricci
发明人： Surekha Palreddy , Carlos Ricci
IPC分类号： A61B5/0428
CPC分类号： A61N1/37 , A61N1/3718 , Y10S128/901
摘要： A system, method, or device determines whether noise is present on a sampled and/or digitized sensed intrinsic cardiac signal based on a moving count of turning/inflection points of the signal. If noise is detected, the manner in which the cardiac signal is acquired, or the manner in which the device operates in response to the acquired cardiac signal (or both) is altered to reduce the risk of erroneously detecting noise as a heart depolarization and, therefore, inappropriately triggering or withholding therapy.
摘要翻译：系统，方法或装置基于信号的转向/拐点的移动计数来确定是否在采样和/或数字化的感测到的固有心脏信号上存在噪声。如果检测到噪声，则改变获取心脏信号的方式或者响应于所获取的心脏信号（或两者）而使装置运行的方式），以降低作为心脏去极化的错误检测噪声的风险，因此，不适当地触发或扣留治疗。

10. 发明申请

US20060200035A1 System and method for signal decomposition, analysis and reconstruction 有权
标题翻译：信号分解，分析和重建的系统和方法
公开(公告)号：US20060200035A1
公开(公告)日：2006-09-07
申请号：US11360223
申请日：2006-02-23
申请人： Carlos Ricci , Vladimir Kovtun
发明人： Carlos Ricci , Vladimir Kovtun
IPC分类号： A61B5/04
CPC分类号： H03H17/0201 , A61B5/0006 , A61B5/04014 , A61B5/0432 , A61B5/044 , G06K9/00523
摘要： The present invention provides a system and method for representing quasi-periodic (“qp”) waveforms comprising, representing a plurality of limited decompositions of the qp waveform, wherein each decomposition includes a first and second amplitude value and at least one time value. In some embodiments, each of the decompositions is phase adjusted such that the arithmetic sum of the plurality of limited decompositions reconstructs the qp waveform. These decompositions are stored into a data structure having a plurality of attributes. Optionally, these attributes are used to reconstruct the qp waveform, or patterns or features of the qp wave can be determined by using various pattern-recognition techniques. Some embodiments provide a system that uses software, embedded hardware or firmware to carry out the above-described method. Some embodiments use a computer-readable medium to store the data structure and/or instructions to execute the method.
摘要翻译：本发明提供一种用于表示准周期（“qp”）波形的系统和方法，包括表示qp波形的多个有限分解，其中每个分解包括第一和第二振幅值和至少一个时间值。在一些实施例中，每个分解被相位调整，使得多个有限分解的算术和重建qp波形。这些分解被存储到具有多个属性的数据结构中。可选地，这些属性用于重建qp波形，或者可以通过使用各种模式识别技术来确定qp波的图案或特征。一些实施例提供使用软件，嵌入式硬件或固件来执行上述方法的系统。一些实施例使用计算机可读介质来存储用于执行该方法的数据结构和/或指令。

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