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1. 发明申请

US20050197563A1 Optical MRI catheter system 失效
标题翻译：光学MRI导管系统
公开(公告)号：US20050197563A1
公开(公告)日：2005-09-08
申请号：US11119677
申请日：2005-05-02
申请人： Jeffrey Helfer , Stuart MacDonald , Robert Gray , Christopher Thomas
发明人： Jeffrey Helfer , Stuart MacDonald , Robert Gray , Christopher Thomas
IPC分类号： A61B5/055 , A61M25/095 , G01R33/28 , A61B5/05
CPC分类号： A61B5/055 , G01R33/285 , G01R33/34084 , G01R33/3692
摘要： An assembly for delivering optical signals comprising a nuclear magnetic resonance system comprised of magnets, an NMR programmable logic unit, a signal input channel, and a command output channel; an optical interface assembly electrically connected to the nuclear magnetic resonance system, the optical interface assembly comprising a first laser modulated so as to produce laser optical signals, an interface optical to electrical signal convertor; and a catheter assembly connected to said optical interface assembly, the catheter assembly comprising a proximal end, a distal end, a fiber optic cable assembly, an electronics assembly disposed at the distal end comprised of a catheter electrical to optical signal convertor and a catheter optical to electrical signal convertor, and a first receiving coil disposed at the distal end.
摘要翻译：一种用于传送光信号的组件，包括由磁体组成的核磁共振系统，NMR可编程逻辑单元，信号输入通道和命令输出通道; 光学接口组件，其电连接到所述核磁共振系统，所述光学接口组件包括被调制以产生激光光信号的第一激光器，光信号到电信号转换器的接口; 以及连接到所述光学接口组件的导管组件，所述导管组件包括近端，远端，光纤电缆组件，设置在远端处的电子组件，所述电子组件包括电导向光信号转换器的导管和导管光学到电信号转换器，以及设置在远端的第一接收线圈。

2. 发明申请

US20050049685A1 Electromagnetic radiation transparent device and method of making thereof 有权
公开(公告)号：US20050049685A1
公开(公告)日：2005-03-03
申请号：US10923292
申请日：2004-08-20
申请人： Robert Gray , Stuart MacDonald , Jeffrey Helfer
发明人： Robert Gray , Stuart MacDonald , Jeffrey Helfer
IPC分类号： A61B5/05 , A61B5/055 , A61B19/00 , A61F2/00 , A61F2/86 , A61F2/90 , A61L31/02 , A61L31/12 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/28 , A61F2/06
CPC分类号： A61B5/02007 , A61B5/055 , A61B2090/374 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2210/009 , A61F2220/0016 , A61L31/022 , A61L31/124 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/285
摘要： A medical device includes a pattern of electrically conductive material. The pattern of electrically conductive material has an anti-antenna geometrical shape such that the anti-antenna geometrical shape substantially prevents the medical device from creating an imaging artifact and/or substantially allows imaging of a volume within the medical device. The pattern may be formed by multiple “figure-8” shaped electrical conductors, multiple “figure-8” emulating electrical conductors, multiple sine-wave-like shaped electrical conductors, multiple zig-zag patterned electrical conductors, by multiple electrical conductors, each having sequential conductive loops, and/or a single conductor weaved into a loop mesh. The electrically conductive material may be titanium, tantalum, nitinol, stainless steel, and/or NbZr.

3. 发明申请

US20050203378A1 Optical MRI catheter system 失效
公开(公告)号：US20050203378A1
公开(公告)日：2005-09-15
申请号：US11119718
申请日：2005-05-02
申请人： Jeffrey Helfer , Stuart MacDonald , Robert Gray , Christopher Thomas
发明人： Jeffrey Helfer , Stuart MacDonald , Robert Gray , Christopher Thomas
IPC分类号： A61B5/055 , A61M25/095 , G01R33/28 , A61B18/18 , A61B5/05
CPC分类号： A61B5/055 , G01R33/285 , G01R33/34084 , G01R33/3692
摘要： An assembly for delivering optical signals comprising a nuclear magnetic resonance system; an optical interface assembly electrically connected to the nuclear magnetic resonance system, the optical interface assembly comprising a first laser for producing laser optical signals, an interface optical to electrical signal convertor, and an interface optical connector assembly; and a catheter assembly comprising a proximal end, a distal end, and a catheter optical connector assembly disposed at the proximal end and connected to the interface optical connector assembly of the optical interface assembly, a fiber optic cable assembly, an electronics assembly disposed at the distal end comprised of a catheter electrical to optical signal convertor and a catheter optical to electrical signal convertor, and a first receiving coil disposed at the distal end.

4. 发明申请

US20050049683A1 Electromagnetic radiation transparent device and method of making thereof 审中-公开
标题翻译：电磁辐射透明装置及其制造方法
公开(公告)号：US20050049683A1
公开(公告)日：2005-03-03
申请号：US10922359
申请日：2004-08-20
申请人： Robert Gray , Stuart MacDonald , Jeffrey Helfer
发明人： Robert Gray , Stuart MacDonald , Jeffrey Helfer
IPC分类号： A61B5/05 , A61B5/055 , A61B19/00 , A61F2/00 , A61F2/86 , A61F2/90 , A61L31/02 , A61L31/12 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/28 , A61F2/06
CPC分类号： A61B5/02007 , A61B5/055 , A61B2090/374 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2210/009 , A61F2220/0016 , A61L31/022 , A61L31/124 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/285
摘要： A medical device includes a pattern of electrically conductive material. The pattern of electrically conductive material has an anti-antenna geometrical shape such that the anti-antenna geometrical shape substantially prevents the medical device from creating an imaging artifact and/or substantially allows imaging of a volume within the medical device. The pattern may be formed by multiple “FIG. 8” shaped electrical conductors, multiple “FIG. 8” emulating electrical conductors, multiple sine-wave-like shaped electrical conductors, multiple zig-zag patterned electrical conductors, by multiple electrical conductors, each having sequential conductive loops, and/or a single conductor weaved into a loop mesh. The electrically conductive material may be titanium, tantalum, nitinol, stainless steel, and/or NbZr.
摘要翻译：医疗装置包括导电材料的图案。导电材料的图案具有抗天线几何形状，使得反天线几何形状基本上防止医疗装置产生成像伪影和/或基本上允许医疗装置内的体积成像。图8可以由多个“<参考对象=”图形形成图8 “成形电导体，多个”<交叉参考目标=“图”>图8 “通过多个电导体，每个具有顺序的导电回路和/或编织成环形网的单个导体来仿真电导体，多个正弦波状电导体，多个锯齿形图案电导体。导电材料可以是钛，钽，镍钛诺，不锈钢和/或NbZr。

5. 发明申请

US20060118319A1 Magnetic resonance imaging coated assembly 失效
公开(公告)号：US20060118319A1
公开(公告)日：2006-06-08
申请号：US11331928
申请日：2006-01-13
申请人： Xingwu Wang , Howard Greenwald , Jeffrey Helfer , Robert Gray , Michael Weiner
发明人： Xingwu Wang , Howard Greenwald , Jeffrey Helfer , Robert Gray , Michael Weiner
IPC分类号： H01B11/06
CPC分类号： G01R33/286 , A61K49/1818 , A61N1/16 , B82Y5/00 , B82Y25/00 , H01B11/10 , H01B11/1083 , H01F10/007 , H01F10/324
摘要： An assembly for shielding an implanted medical device from the effects of high-frequency radiation and for emitting magnetic resonance signals during magnetic resonance imaging. The assembly includes an implanted medical device and a magnetic shield comprised of nanomagnetic material disposed between the medical device and the high-frequency radiation. In one embodiment, the magnetic resonance signals are detected by a receiver, which is thus able to locate the implanted medical device within a biological organism.

6. 发明申请

US20060030774A1 Magnetic resonance imaging interference immune device 有权
标题翻译：磁共振成像干扰免疫装置
公开(公告)号：US20060030774A1
公开(公告)日：2006-02-09
申请号：US11248862
申请日：2005-10-12
申请人： Robert Gray , Jeffrey Helfer
发明人： Robert Gray , Jeffrey Helfer
IPC分类号： A61B6/00 , A61M25/00
CPC分类号： A61N1/37 , A61N1/05 , A61N1/086 , A61N1/3718 , G01R33/3685
摘要： A medical assembly includes a multi-wire lead having a plurality of coiling loops. The multi-wire lead has a gap region and a non-gap region. The gap region has adjacent coiling loops of the multi-wire lead with gaps therebetween so as to form different impedance in the gap region than impedance in the non-gap region. The non-gap region has adjacent coiling loops of the multi-wire lead with no gaps therebetween. The gaps may provide inter-loop capacitance. The multi-wire lead may have a plurality of gap regions, each gap region having a non-gap region therebetween.
摘要翻译：医疗组件包括具有多个卷绕环的多线引线。多线引线具有间隙区域和非间隙区域。间隙区域具有在其间具有间隙的多线引线的相邻卷绕环，以便在间隙区域中形成与非间隙区域中的阻抗不同的阻抗。非间隙区域具有多线引线的相邻卷绕环，其间没有间隙。间隙可以提供环路间电容。多线引线可以具有多个间隙区域，每个间隙区域之间具有非间隙区域。

7. 发明申请

US20050049686A1 Electromagnetic radiation transparent device and method of making thereof 审中-公开
标题翻译：电磁辐射透明装置及其制造方法
公开(公告)号：US20050049686A1
公开(公告)日：2005-03-03
申请号：US10923411
申请日：2004-08-20
申请人： Robert Gray , Jeffrey Helfer
发明人： Robert Gray , Jeffrey Helfer
IPC分类号： A61B5/05 , A61B5/055 , A61B19/00 , A61F2/00 , A61F2/86 , A61F2/90 , A61L31/02 , A61L31/12 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/28 , A61F2/06
CPC分类号： A61B5/02007 , A61B5/055 , A61B2090/374 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2210/009 , A61F2220/0016 , A61L31/022 , A61L31/124 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/285
摘要： A medical device includes a pattern of electrically conductive material. The pattern of electrically conductive material has an anti-antenna geometrical shape such that the anti-antenna geometrical shape substantially prevents the medical device from creating an imaging artifact and/or substantially allows imaging of a volume within the medical device. The pattern may be formed by multiple “figure-8” shaped electrical conductors, multiple “figure-8” emulating electrical conductors, multiple sine-wave-like shaped electrical conductors, multiple zig-zag patterned electrical conductors, by multiple electrical conductors, each having sequential conductive loops, and/or a single conductor weaved into a loop mesh. The electrically conductive material may be titanium, tantalum, nitinol, stainless steel, and/or NbZr.
摘要翻译：医疗装置包括导电材料的图案。导电材料的图案具有抗天线几何形状，使得反天线几何形状基本上防止医疗装置产生成像伪影和/或基本上允许医疗装置内的体积成像。该图案可以由多个“图8”形电导体，多个“图8”仿真电导体，多个正弦波状电导体，多个锯齿形图案电导体，由多个电导体，每个具有顺序导电回路，和/或编织成环网的单个导体。导电材料可以是钛，钽，镍钛诺，不锈钢和/或NbZr。

8. 发明申请

US20050049689A1 Electromagnetic radiation transparent device and method of making thereof 审中-公开
公开(公告)号：US20050049689A1
公开(公告)日：2005-03-03
申请号：US10923294
申请日：2004-08-20
申请人： Robert Gray , Jeffrey Helfer
发明人： Robert Gray , Jeffrey Helfer
IPC分类号： A61B5/05 , A61B5/055 , A61B19/00 , A61F2/00 , A61F2/86 , A61F2/90 , A61L31/02 , A61L31/12 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/28 , A61F2/06
CPC分类号： A61B5/02007 , A61B5/055 , A61B2090/374 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2210/009 , A61F2220/0016 , A61L31/022 , A61L31/124 , A61L31/18 , A61N1/16 , A61N2/00 , G01R33/285
摘要： A medical device includes a pattern of electrically conductive material. The pattern of electrically conductive material has an anti-antenna geometrical shape such that the anti-antenna geometrical shape substantially prevents the medical device from creating an imaging artifact and/or substantially allows imaging of a volume within the medical device. The pattern may be formed by multiple “figure-8” shaped electrical conductors, multiple “figure-8” emulating electrical conductors, multiple sine-wave-like shaped electrical conductors, multiple zig-zag patterned electrical conductors, by multiple electrical conductors, each having sequential conductive loops, and/or a single conductor weaved into a loop mesh. The electrically conductive material may be titanium, tantalum, nitinol, stainless steel, and/or NbZr.

9. 发明申请

US20060140867A1 Coated stent assembly and coating materials 审中-公开
标题翻译：涂层支架组件和涂层材料
公开(公告)号：US20060140867A1
公开(公告)日：2006-06-29
申请号：US11128591
申请日：2005-05-13
申请人： Jeffrey Helfer , Xingwu Wang , Robert Gray , Howard Greenwald
发明人： Jeffrey Helfer , Xingwu Wang , Robert Gray , Howard Greenwald
IPC分类号： A61K49/06
CPC分类号： A61K49/1821 , B82Y5/00
摘要： A high magnetic susceptibility nanomagnetic material that may be attached to recognition molecules and other therapeutic biological materials so as to be targeted to specific biologic tissues, thereby enabling the presence of the targeted tissue to be detected under magnetic resonance imaging with much greater sensitivity. Also a stent coated with such nanomagnetic material to enable artifact free imaging of such stent under magnetic resonance imaging.
摘要翻译：可以附着到识别分子和其他治疗生物材料上以便靶向特定生物组织的高磁化率纳米磁性材料，从而使得能够以更高的灵敏度在磁共振成像下存在待检测的靶组织。还有一种涂有这种纳米磁性材料的支架，以在磁共振成像下能够对这种支架进行无伪影成像。

10. 发明申请

US20050178584A1 Coated stent and MR imaging thereof 审中-公开
标题翻译：涂层支架及其MR成像
公开(公告)号：US20050178584A1
公开(公告)日：2005-08-18
申请号：US11052263
申请日：2005-02-07
申请人： Xingwu Wang , Robert Gray , Jeffrey Helfer
发明人： Xingwu Wang , Robert Gray , Jeffrey Helfer
IPC分类号： A61F2/06
CPC分类号： A61L31/088 , A61F2/82 , A61L31/14 , A61L2400/12
摘要： Disclosed in this specification is a stent coated with a layer comprised of particulates which have an average particle size of less than 100 nanometers; a saturation magnetization of at least 2,000 gauss; and where the average coherence length between the particulates is from about 1 nanometer to about 50 nanometers.
摘要翻译：在本说明书中公开了一种涂覆有平均粒径小于100纳米的颗粒的层的支架; 至少2,000高斯的饱和磁化强度; 并且其中颗粒之间的平均相干长度为约1纳米至约50纳米。

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