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1. 发明申请

US20070093846A1 Apparatus and methods for vertebral augmentation 有权
标题翻译：用于脊椎增大的装置和方法
公开(公告)号：US20070093846A1
公开(公告)日：2007-04-26
申请号：US11546579
申请日：2006-10-10
申请人： Robert Frigg , Christof Dutoit , Andreas Appenzeller , Thierry Stoll , Alfred Benoit , Christoph Fuerst , Paul Heini
发明人： Robert Frigg , Christof Dutoit , Andreas Appenzeller , Thierry Stoll , Alfred Benoit , Christoph Fuerst , Paul Heini
IPC分类号： A61B17/58
CPC分类号： A61B17/7077 , A61B17/025 , A61B17/7079 , A61B17/8805 , A61B2017/0256
摘要： Apparatuses and methods of treating a collapsed vertebra may include inserting cannulae into the damaged vertebral body and one or more adjacent vertebral bodies and repositioning the one or more adjacent vertebral bodies by manipulating one or more of the cannulae. Before or after repositioning the vertebral bodies, the method may further include passing through the cannula and into the damaged vertebra a disruption tool for fracturing the damaged vertebral body. Once the cortical bone is broken or otherwise disrupted, the height of the damaged vertebral body may be restored, for example by removing the disruption tool and inserting through the cannula another tool, implant, device and/or material to restore the height of the vertebral body and to restore normal spinal curvature in the affected area. Bone cement, bone chips, demineralized bone or other grafting material or filler may be added with or without an implanted device to augment the damaged vertebral body.
摘要翻译：治疗塌陷椎骨的装置和方法可以包括将插入物插入损伤的椎体和一个或多个相邻的椎体中，并通过操纵一个或多个插管重新定位所述一个或多个相邻的椎体。在重新定位椎体之前或之后，该方法还可以包括穿过套管并进入损伤的椎骨中，用于破坏受损椎体的破裂工具。一旦皮质骨被破坏或以其他方式破坏，可以恢复受损椎体的高度，例如通过去除破碎工具并插入穿过套管的另一工具，植入物，装置和/或材料以恢复脊椎的高度并恢复受影响区域的正常脊柱弯曲。可以在有或没有植入装置的情况下添加骨水泥，骨碎片，软化骨或其它接枝材料或填充物，以增加损伤的椎体。

2. 发明授权

US08157806B2 Apparatus and methods for vertebral augmentation 有权
标题翻译：用于脊椎增大的装置和方法
公开(公告)号：US08157806B2
公开(公告)日：2012-04-17
申请号：US11546579
申请日：2006-10-10
申请人： Robert Frigg , Christof Dutoit , Andreas Appenzeller , Thierry Stoll , Alfred Benoit , Christoph Fuerst , Paul Heini
发明人： Robert Frigg , Christof Dutoit , Andreas Appenzeller , Thierry Stoll , Alfred Benoit , Christoph Fuerst , Paul Heini
IPC分类号： A61B17/70
CPC分类号： A61B17/7077 , A61B17/025 , A61B17/7079 , A61B17/8805 , A61B2017/0256
摘要： Apparatuses and methods of treating a collapsed vertebra may include inserting cannulae into the damaged vertebral body and one or more adjacent vertebral bodies and repositioning the one or more adjacent vertebral bodies by manipulating one or more of the cannulae. Before or after repositioning the vertebral bodies, the method may further include passing through the cannula and into the damaged vertebra a disruption tool for fracturing the damaged vertebral body. Once the cortical bone is broken or otherwise disrupted, the height of the damaged vertebral body may be restored, for example by removing the disruption tool and inserting through the cannula another tool, implant, device and/or material to restore the height of the vertebral body and to restore normal spinal curvature in the affected area. Bone cement, bone chips, demineralized bone or other grafting material or filler may be added with or without an implanted device to augment the damaged vertebral body.
摘要翻译：治疗塌陷椎骨的装置和方法可以包括将插入物插入损伤的椎体和一个或多个相邻的椎体中，并通过操纵一个或多个插管重新定位所述一个或多个相邻的椎体。在重新定位椎体之前或之后，该方法还可以包括穿过套管并进入损伤的椎骨中，用于破坏受损椎体的破裂工具。一旦皮质骨被破坏或以其他方式破坏，可以恢复受损椎体的高度，例如通过去除破碎工具并插入穿过套管的另一工具，植入物，装置和/或材料以恢复脊椎的高度并恢复受影响区域的正常脊柱弯曲。可以在有或没有植入装置的情况下添加骨水泥，骨碎片，软化骨或其它接枝材料或填充物，以增加损伤的椎体。

3. 发明申请

US20070093899A1 Apparatus and methods for treating bone 审中-公开
标题翻译：用于治疗骨骼的装置和方法
公开(公告)号：US20070093899A1
公开(公告)日：2007-04-26
申请号：US11527280
申请日：2006-09-25
申请人： Christof Dutoit , Andreas Appenzeller , Thierry Stoll , Alfred Benoit , Stefan Mathys , Simon Stucki
发明人： Christof Dutoit , Andreas Appenzeller , Thierry Stoll , Alfred Benoit , Stefan Mathys , Simon Stucki
IPC分类号： A61F2/44
CPC分类号： A61B17/7097 , A61B17/3421 , A61B17/686 , A61B17/8855 , A61B17/8858 , A61B2017/00292 , A61B2017/005 , A61B2017/00557 , A61B2017/00867
摘要： Implants and methods for minimally invasive augmentation and repositioning of vertebrae may comprise one or more expandable members, e.g., stents, implants, surrounding a balloon-tipped catheter or other expansion device, inserted into a vertebral body or other bone. Expansion of the expandable member within the vertebral body or other bone may reposition the fractured bone to a desired height and augment the bone to maintain the desired height. A bone cement or other filler can be added to further augment and stabilize the vertebral body or other bone.
摘要翻译：植入物和用于椎体的微创增加和重新定位的方法可以包括一个或多个可扩张构件，例如，插入椎体或其他骨中的支架，植入物，围绕球囊导管或其它扩张装置。可扩展构件在椎体或其他骨骼内的扩张可以将骨折骨重新定位到期望的高度并增加骨骼以保持所需的高度。可以加入骨水泥或其他填充物以进一步增加和稳定椎体或其他骨。

4. 发明授权

US08080061B2 Apparatus and methods for treating bone 有权
标题翻译：用于治疗骨骼的装置和方法
公开(公告)号：US08080061B2
公开(公告)日：2011-12-20
申请号：US11471169
申请日：2006-06-19
申请人： Andreas Appenzeller , Christof Dutoit , Alfred Benoit , Thierry Stoll , Erich Röthlisberger , Stefan Mathys
发明人： Andreas Appenzeller , Christof Dutoit , Alfred Benoit , Thierry Stoll , Erich Röthlisberger , Stefan Mathys
IPC分类号： A61F2/44 , A61B17/58
CPC分类号： A61B17/742 , A61B17/7062 , A61B17/7095 , A61B17/8852 , A61B17/8858 , A61B2017/0256
摘要： Implants and methods for bone treatment, preferably minimally invasive treatment, including repositioning of vertebrae may comprise insertion of a bobbin having a wire, string, thread or band, coiled around the bobbin. During coiling, the diameter of the bobbing/band complex may increase. Such increase in diameter can push against the inner side of the endplates of the vertebral body, and augment the vertebral body to its original height. The implant may also take the form of a coiled sleeve which when inserted into the vertebral body is uncoiled. The force of the uncoiling sleeve pushes against the inner side of the endplates of the vertebral body, restoring the vertebral body to its original height. The implant may also take the form of fibrous masses comprised of a thread or other relatively thin structure, for example a fiber or strand, of any biocompatible material having desired characteristics, for example a shape memory alloy, titanium, stainless steel, another metal or metal alloy, a ceramic, a composite or any combination thereof. The, strand, thread or other fiber may be coiled, woven, matted, tangled or otherwise formed into a wool-like mass or body having a desired configuration. Expansion of the expandable member within the vertebral body or other bone may reposition the fractured bone to a desired height and augment the bone to maintain the desired height. A bone cement or other filler can be added to further treat and stabilize the vertebral body or other bone.
摘要翻译：用于骨治疗的植入物和方法，优选微创治疗，包括椎骨的重新定位可以包括插入线圈，线圈，线或线圈绕线圈。在卷取期间，摆动/带复合体的直径可能增加。这种直径的增加可以推动椎体的终板的内侧，并将椎体增加到其原始高度。植入物也可以采取螺旋形套筒的形式，当插入到椎体中时，其被展开。开卷套筒的力推动椎体的端板的内侧，将椎体恢复到原来的高度。植入物也可以采取由具有所需特征的任何具有所需特征的生物相容性材料，例如形状记忆合金，钛，不锈钢，另一种金属的线或其它较薄结构（例如纤维或股线）组成的纤维质量的形式，金属合金，陶瓷，复合材料或其组合。线，线或其他纤维可以卷绕，编织，消光，缠结或以其它方式形成具有所需构型的羊毛状物质或身体。可扩展构件在椎体或其他骨骼内的扩张可以将骨折骨重新定位到期望的高度并增加骨骼以保持所需的高度。可以加入骨水泥或其他填料以进一步治疗和稳定椎体或其他骨。

5. 发明申请

US20070055274A1 Apparatus and methods for treating bone 有权
标题翻译：用于治疗骨骼的装置和方法
公开(公告)号：US20070055274A1
公开(公告)日：2007-03-08
申请号：US11471169
申请日：2006-06-19
申请人： Andreas Appenzeller , Christof Dutoit , Alfred Benoit , Thierry Stoll , Erich Rothlisberger , Stefan Mathys
发明人： Andreas Appenzeller , Christof Dutoit , Alfred Benoit , Thierry Stoll , Erich Rothlisberger , Stefan Mathys
IPC分类号： A61B17/58
CPC分类号： A61B17/742 , A61B17/7062 , A61B17/7095 , A61B17/8852 , A61B17/8858 , A61B2017/0256
摘要： Implants and methods for bone treatment, preferably minimally invasive treatment, including repositioning of vertebrae may comprise insertion of a bobbin having a wire, string, thread or band, coiled around the bobbin. During coiling, the diameter of the bobbing/band complex may increase. Such increase in diameter can push against the inner side of the endplates of the vertebral body, and augment the vertebral body to its original height. The implant may also take the form of a coiled sleeve which when inserted into the vertebral body is uncoiled. The force of the uncoiling sleeve pushes against the inner side o the endplates of the vertebral body, restoring the vertebral body to its original height. The implant may also take the form of fibrous masses comprised of a thread or other relatively thin structure, for example a fiber or strand, of any biocompatible material having desired characteristics, for example a shape memory alloy, titanium, stainless steel, another metal or metal alloy, a ceramic, a composite or any combination thereof. The, strand, thread or other fiber may be coiled, woven, matted, tangled or otherwise formed into a wool-like mass or body having a desired configuration. Expansion of the expandable member within the vertebral body or other bone may reposition the fractured bone to a desired height and augment the bone to maintain the desired height. A bone cement or other filler can be added to further treat and stabilize the vertebral body or other bone.
摘要翻译：用于骨治疗的植入物和方法，优选微创治疗，包括椎骨的重新定位可以包括插入线圈，线圈，线或线圈绕线圈。在卷取期间，摆动/带复合体的直径可能增加。这种直径的增加可以推动椎体的终板的内侧，并将椎体增加到其原始高度。植入物也可以采取螺旋形套筒的形式，当插入到椎体中时，其被展开。开卷套筒的力推动椎体的端板的内侧，将椎体恢复到原来的高度。植入物也可以采取由具有所需特征的任何具有所需特征的生物相容性材料，例如形状记忆合金，钛，不锈钢，另一种金属的线或其它较薄结构（例如纤维或股线）组成的纤维质量的形式，金属合金，陶瓷，复合材料或其组合。线，线或其他纤维可以卷绕，编织，消光，缠结或以其它方式形成具有所需构型的羊毛状物质或身体。可扩展构件在椎体或其他骨骼内的扩张可以将骨折骨重新定位到期望的高度并增加骨骼以保持所需的高度。可以加入骨水泥或其他填料以进一步治疗和稳定椎体或其他骨。

6. 发明授权

US6143031A Intervertebral implant with compressible shaped hollow element 失效
标题翻译：椎间植入物与可压缩形状的中空元件
公开(公告)号：US6143031A
公开(公告)日：2000-11-07
申请号：US51770
申请日：1998-04-20
申请人： Inga Knothe , Alfred Benoit
发明人： Inga Knothe , Alfred Benoit
IPC分类号： A61F2/00 , A61F2/28 , A61F2/30 , A61F2/44
CPC分类号： A61F2/4455 , A61F2/30767 , A61F2/442 , A61F2002/2835 , A61F2002/30235 , A61F2002/305 , A61F2002/30563 , A61F2002/30777 , A61F2002/30785 , A61F2002/30789 , A61F2002/3082 , A61F2002/4475 , A61F2220/0025 , A61F2230/0069 , A61F2310/00023 , A61F2310/00796 , Y10S606/90 , Y10S606/907 , Y10S606/909 , Y10S606/91 , Y10S606/911
摘要： An intervertebral implant for fusion of vertebral bodies is disclosed. The implant includes a flattened shaped hollow element in the form of a hollow cylinder, hollow truncated cone, hollow truncated pyramid, or hollow truncated wedge, with an outer surface having a flattened upper bone-contact face, flattened lower bone contact face, and two lateral faces. The upper and lower bone-contact faces can be elastically compressed towards the interior space of the hollow element in such a way that the maxi mum distance between the upper and lower contact faces can be reduced by 0.5 to 5.0 mm. The compressibility of the implant allows the insertion of the implant without the need for distracting the vertebras. After the implant is implanted, the engagement of an engagement lip with an interlock means prevents the compression of the implant.
摘要翻译： PCT No.PCT / CH95 / 00244 Sec。 371日期：1998年4月20日 102（e）1998年4月20日PCT PCT 1995年10月20日PCT公布。出版物WO97 / 15247 日期：1997年5月1日公开了用于椎体融合的椎间植入物。植入物包括中空圆筒形的扁平形状的中空元件，中空截顶锥体，中空截顶棱锥体或中空截顶楔形物，其外表面具有平坦的上骨接触面，扁平的下骨接触面和两个侧面。上下骨接触面可以以中空元件的内部空间弹性压缩，使得上下接触面之间的最大距离可以减小0.5至5.0mm。植入物的压缩性允许植入物的插入，而不需要使脊椎动物分散注意力。在植入物植入之后，接合唇与互锁装置的接合防止植入物的压缩。

7. 发明授权

US06443990B1 Adjustable intervertebral implant 失效
标题翻译：可调椎间植入物
公开(公告)号：US06443990B1
公开(公告)日：2002-09-03
申请号：US09664731
申请日：2000-09-19
申请人： Max Aebi , Inga Knothe , Alfred Benoit
发明人： Max Aebi , Inga Knothe , Alfred Benoit
IPC分类号： A61F244
CPC分类号： A61F2/4601 , A61F2/4455 , A61F2/446 , A61F2/4611 , A61F2002/30131 , A61F2002/30143 , A61F2002/30405 , A61F2002/30538 , A61F2002/3054 , A61F2002/30556 , A61F2002/30579 , A61F2002/30774 , A61F2002/3085 , A61F2002/4627 , A61F2220/0025 , A61F2230/0013 , A61F2230/0017 , A61F2250/0006 , A61F2250/0009
摘要： An intervertebral implant in the form of a support unit with a central yoke and four legs extending in a direction is described. The legs are configured in two substantially mutually parallel planes spaced apart by the yoke and are abuttable as support surfaces against adjacent vertebrae. A guide cylinder extending from the yoke in the same direction as the legs has at least on threaded surface. A dilator member is adapted to be fixed to the guide cylinder and to deformably spread the legs of the intervertebral implant a predetermined amount. The gaps between the legs which the dilator member spreads may have grooves to arrest the dilator member in a predetermined location.
摘要翻译：描述了具有中心轭和沿一个方向延伸的四个腿的支撑单元形式的椎间植入物。腿部构造成由轭架间隔开的两个基本相互平行的平面，并且可抵靠相邻椎骨的支撑表面。引导圆柱体从轭架沿与腿部相同的方向延伸至少具有螺纹表面。扩张器构件适于固定到引导筒并且使椎间植入物的腿部可变形地展开预定量。扩张器构件扩展的腿之间的间隙可以具有凹槽以将扩张器构件阻止在预定位置。

8. 发明授权

US06503279B1 Intervertebral implant 有权
标题翻译：椎间植入物
公开(公告)号：US06503279B1
公开(公告)日：2003-01-07
申请号：US09254206
申请日：1999-03-03
申请人： John Webb , Inga Maren Häfeli-Knothe , Thomas Häfeli , Alfred Benoit
发明人： John Webb , Inga Maren Häfeli-Knothe , Thomas Häfeli , Alfred Benoit
IPC分类号： A61F244
CPC分类号： A61L27/56 , A61F2/30771 , A61F2/442 , A61F2/4465 , A61F2/447 , A61F2/4611 , A61F2002/2835 , A61F2002/30062 , A61F2002/3023 , A61F2002/30235 , A61F2002/30271 , A61F2002/30772 , A61F2002/3082 , A61F2002/30828 , A61F2002/30831 , A61F2002/30892 , A61F2002/4475 , A61F2210/0004 , A61F2230/0069 , A61F2230/0082 , A61L27/10 , A61L2430/38 , Y10S606/908 , Y10S606/912
摘要： The present invention relates to an intervertebral implant for fusion of vertebrae. The implant has top and bottom surfaces configured and dimensioned to contact end plates of the vertebrae and a jacket forming a side surface of the implant and having a three-dimensional texture for promoting initial stability. The implant is made of a porous ceramic material. The implant according to this invention is characterized in that upon primary fusion during the resorption process, it equalizes the distance (corresponding to intervertebral disk height) between two vertebrae while providing adequate fusion and is resorbed by the body after a certain amount of time.
摘要翻译：本发明涉及用于椎骨融合的椎间植入物。植入物具有顶部和底部表面，其被构造和尺寸设计成接触椎骨的端板和形成植入物的侧表面的护套并具有用于促进初始稳定性的三维织构。植入物由多孔陶瓷材料制成。根据本发明的植入物的特征在于，在再吸收过程中的初次融合时，其在提供足够的融合物的同时平衡两个椎骨之间的距离（对应于椎间盘高度），并在一定时间后被身体吸收。

9. 发明授权

US5888228A Intervertebral implant with cage and rotating element 失效
标题翻译：具有保持架和旋转元件的椎间植入物
公开(公告)号：US5888228A
公开(公告)日：1999-03-30
申请号：US11014
申请日：1998-02-02
申请人： Inga Knothe , Alfred Benoit
发明人： Inga Knothe , Alfred Benoit
IPC分类号： A61B17/86 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/446 , A61F2/447 , A61B17/86 , A61F2/30744 , A61F2/442 , A61F2/4611 , A61F2002/2835 , A61F2002/30153 , A61F2002/30158 , A61F2002/3021 , A61F2002/30235 , A61F2002/30271 , A61F2002/30283 , A61F2002/30291 , A61F2002/30382 , A61F2002/30403 , A61F2002/30504 , A61F2002/30593 , A61F2002/30777 , A61F2002/30845 , A61F2002/30848 , A61F2002/3085 , A61F2002/30904 , A61F2002/30975 , A61F2002/4475 , A61F2220/0025 , A61F2220/0033 , A61F2230/0019 , A61F2230/0026 , A61F2230/0063 , A61F2230/0067 , A61F2230/0069 , A61F2230/0082 , A61F2230/0091 , A61F2310/00023 , A61F2310/00179
摘要： The intervertebral implant comprises a frame-type cage (1) which is open at its top and base faces (11 and 12 respectively) with two lateral faces (13, 14), a front wall (15) and a rear wall (16). A rotating element (2) is mounted in the cage (1) so as to be capable of rotation. The outer surface of the rotating element (2) is provided with a helical structure (21). The helical structure (21) protrudes beyond the cover and base faces (11, 12) outside the confines of the cage (1). The front wall (15) has an aperture (17) for the introduction of a drive tool with which the rotating element (2) in the cage (1) can be made to rotate.
摘要翻译： PCT No.PCT / CH95 / 00243 Sec。 371日期1998年2月2日 102（e）1998年2月2日PCT 1995年10月20日PCT PCT。公开号WO97 / 15246 日期1997年5月1日椎间植入物包括框架式保持架（1），其在其顶部和底面（分别为11和12）处开有两个侧面（13,14），前壁（15）和后墙（16）。旋转元件（2）安装在保持器（1）中以便能够旋转。旋转元件（2）的外表面设置有螺旋结构（21）。螺旋结构（21）在保持架（1）的限制之外突出超过盖和基面（11,12）。前壁（15）具有用于引入驱动工具的孔（17），可以使保持器（1）中的旋转元件（2）旋转。

10. 发明授权

US06843805B2 Intervertebral implant 有权
标题翻译：椎间植入物
公开(公告)号：US06843805B2
公开(公告)日：2005-01-18
申请号：US10337267
申请日：2003-01-07
申请人： John Webb , Inga Maren Häfeli-Knothe , Thomas Häfeli , Alfred Benoit
发明人： John Webb , Inga Maren Häfeli-Knothe , Thomas Häfeli , Alfred Benoit
IPC分类号： A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46 , A61L27/10 , A61L27/56 , A61B17/70
CPC分类号： A61L27/56 , A61F2/30771 , A61F2/442 , A61F2/4465 , A61F2/447 , A61F2/4611 , A61F2002/2835 , A61F2002/30062 , A61F2002/3023 , A61F2002/30235 , A61F2002/30271 , A61F2002/30772 , A61F2002/3082 , A61F2002/30828 , A61F2002/30831 , A61F2002/30892 , A61F2002/4475 , A61F2210/0004 , A61F2230/0069 , A61F2230/0082 , A61L27/10 , A61L2430/38 , Y10S606/908 , Y10S606/912
摘要： The present invention relates to an intervertebral implant for fusion of vertebrae. The implant has top and bottom surfaces configured and dimensioned to contact end plates of the vertebrae and a jacket forming a side surface of the implant and having a three-dimensional texture for promoting initial stability. The implant is made of a porous ceramic material. The implant according to this invention is characterized in that upon primary fusion during the resorption process, it equalizes the distance (corresponding to intervertebral disk height) between two vertebrae while providing adequate fusion and is resorbed by the body after a certain amount of time.
摘要翻译：本发明涉及用于椎骨融合的椎间植入物。植入物具有顶部和底部表面，其被构造和尺寸设计成接触椎骨的端板和形成植入物的侧表面的护套并具有用于促进初始稳定性的三维织构。植入物由多孔陶瓷材料制成。根据本发明的植入物的特征在于，在再吸收过程中的初次融合时，其在提供足够的融合物的同时平衡两个椎骨之间的距离（对应于椎间盘高度），并在一定时间后被身体吸收。

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