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1. 发明授权

US5322165A Sharp instrument encasement system 失效
标题翻译：夏普仪器包装系统
公开(公告)号：US5322165A
公开(公告)日：1994-06-21
申请号：US17578
申请日：1993-02-16
申请人： Richard J. Melker , Gary J. Miller , Christopher D. Batich
发明人： Richard J. Melker , Gary J. Miller , Christopher D. Batich
IPC分类号： A61M5/00 , A61M5/31 , A61M5/32
CPC分类号： A61M5/002 , A61M5/3213 , A61M2005/3109 , A61M2005/328
摘要： A sharp instrument encasement system is disclosed for encasing the sharp points or edges of medical instruments. The system comprises a container having two fluid-tight compartments separated by a frangible membrane, one compartment containing a hardenable resin and the other containing a filler comprising a particulate material that is substantially incompressible. Upon insertion of a medical instrument through a penetrable top and through the frangible membrane, the contents of the compartments mix, creating a reaction that hardens the resin and particulate material mixture and encases the sharp portions of the medical instrument.
摘要翻译：公开了一种尖锐的仪器包装系统，用于包裹医疗器械的尖锐点或边缘。该系统包括具有由易碎膜隔开的两个流体密封隔室的容器，一个容纳可硬化树脂的隔室，另一个容器包含基本不可压缩的颗粒材料的填料。当医疗器械通过可穿透顶部并通过易碎膜插入时，隔室的内容物混合，产生使树脂和颗粒材料混合物硬化并包裹医疗器械的尖锐部分的反应。

2. 发明授权

US5431655A Intraosseous needle 失效
标题翻译：骨内针
公开(公告)号：US5431655A
公开(公告)日：1995-07-11
申请号：US74216
申请日：1993-06-09
申请人： Richard J. Melker , Peter F. Gearen , Gary J. Miller , Michael P. DeBruyne , Lisa Molitor
发明人： Richard J. Melker , Peter F. Gearen , Gary J. Miller , Michael P. DeBruyne , Lisa Molitor
IPC分类号： A61B17/34 , A61B17/86 , A61B17/88 , A61B17/00 , A61M5/00
CPC分类号： A61B17/3472 , A61B17/864 , A61B17/8811
摘要： An intraosseous needle having a threaded shaft with a passageway extending substantially therethrough, a solid and pointed tip at one end thereof, the tip having a plurality of cutting edges which facilitate boring through a bone. The shaft also includes two side ports in communication with the passageway to allow fluids to pass through the needle into the interior of the bone after successful insertion thereof. There is a hub at the opposite end of the shaft, whereby the needle is adapted to couple with an appropriate gripping device. A handle is provided in the shape of a ball knob and is adapted to telescopically and grippingly receive the hub of the needle. The hub and handle are both equipped with mutually engaging torque-transmitting surfaces.
摘要翻译：具有螺纹轴的骨内针，其具有基本上穿过其延伸的通道，在其一端具有固体和尖端，所述尖端具有多个切削刃，其有利于穿过骨。轴还包括与通道连通的两个侧端口，以允许流体在其成功插入之后通过针进入骨的内部。在轴的相对端具有毂，由此针适于与适当的夹持装置联接。手柄设置成球形旋钮的形状，并且适于伸缩地并且夹紧地容纳针的轮毂。轮毂和手柄均配有相互接合的扭矩传递表面。

3. 发明授权

US5601559A Intraosseous needle 失效
标题翻译：骨内针
公开(公告)号：US5601559A
公开(公告)日：1997-02-11
申请号：US192006
申请日：1994-02-04
申请人： Richard J. Melker , Peter F. Gearen , Gary J. Miller , Michael P. DeBruyne , Lisa Molitor
发明人： Richard J. Melker , Peter F. Gearen , Gary J. Miller , Michael P. DeBruyne , Lisa Molitor
IPC分类号： A61B17/34 , A61B17/86 , A61B17/88 , A61B5/00
CPC分类号： A61B17/3472 , A61B17/864 , A61B17/8811
摘要： An intraosseous needle having a threaded shaft with a passageway extending substantially therethrough, a solid and pointed tip at one end thereof, the tip having a plurality of cutting edges which facilitate boring through a bone. The shaft also includes two side ports in communication with the passageway to allow fluids to pass through the needle into the interior of the Done after successful insertion thereof. There is a hub at the opposite end of the shaft, whereby the needle is adapted to couple with an appropriate gripping device. A handle is provided in the shape of a ball knob and is adapted to telescopically and grippingly receive the hub of the needle. The hub and handle are both equipped with mutually engaging torque-transmitting surfaces. Additionally, the threads of the intraosseous needle may optionally be tapered so that at least one thread at the proximal end of the threaded shaft has a greater major (and/or minor) diameter than at least one thread located at the distal end of the threaded shaft. As the needle is inserted, the tapering of the threads provides a tighter fit between the bone and the needle to prevent needle wobble and fluid leakage.
摘要翻译：具有螺纹轴的骨内针，其具有基本上穿过其延伸的通道，在其一端具有固体和尖端，所述尖端具有多个切削刃，其有利于穿过骨。轴还包括与通道连通的两个侧端口，以允许流体在其成功插入之后通过针进入Done的内部。在轴的相对端具有毂，由此针适于与适当的夹持装置联接。手柄设置成球形旋钮的形状，并且适于伸缩地并且夹紧地容纳针的轮毂。轮毂和手柄均配有相互接合的扭矩传递表面。此外，骨内针的螺纹可以可选地是锥形的，使得在螺纹轴的近端处的至少一个螺纹具有比位于螺纹的远端处的至少一个螺纹的更大的主要（和/或次要）直径轴。当针被插入时，螺纹的锥形使得骨头和针之间的紧密配合以防止针头摆动和流体泄漏。

4. 发明授权

US5484442A Intraosseous needle 失效
标题翻译：骨内针
公开(公告)号：US5484442A
公开(公告)日：1996-01-16
申请号：US884323
申请日：1992-05-11
申请人： Richard J. Melker , Peter F. Gearen , Gary J. Miller , Michael P. DeBruyne , Lisa Molitor
发明人： Richard J. Melker , Peter F. Gearen , Gary J. Miller , Michael P. DeBruyne , Lisa Molitor
IPC分类号： A61B17/34 , A61B17/86 , A61B17/88 , A61B17/00
CPC分类号： A61B17/3472 , A61B17/864 , A61B17/8811
摘要： An intraosseous needle having a threaded shaft with a passageway extending substantially therethrough, a solid and pointed tip at one end thereof, the tip having a plurality of cutting edges which facilitate boring through a bone. The shaft also includes two side ports in communication with the passageway to allow fluids to pass through the needle into the interior of the bone after successful insertion thereof. There is a hub at the opposite end of the shaft, whereby the needle is adapted to coupled with an appropriate gripping device. A handle is provided in the shape of a ball knob and is adapted to telescopically and grippingly receive the hub of the needle. The hub and handle are both equipped with mutually engaging torque-transmitting surfaces.
摘要翻译：具有螺纹轴的骨内针，其具有基本上穿过其延伸的通道，在其一端具有固体和尖端，所述尖端具有多个切削刃，其有利于穿过骨。轴还包括与通道连通的两个侧端口，以允许流体在其成功插入之后通过针进入骨的内部。在轴的相对端具有毂，由此针适于与适当的夹持装置联接。手柄设置成球形旋钮的形状，并且适于伸缩地并且夹紧地容纳针的轮毂。轮毂和手柄均配有相互接合的扭矩传递表面。

5. 发明授权

US5135492A Arterial/venous fluid transfer system 失效
标题翻译：运动/静音流体传送系统
公开(公告)号：US5135492A
公开(公告)日：1992-08-04
申请号：US371378
申请日：1989-06-26
申请人： Richard J. Melker , Gary J. Miller
发明人： Richard J. Melker , Gary J. Miller
IPC分类号： A61B5/15 , A61M39/00 , A61M39/02 , A61M39/04
CPC分类号： A61M39/04 , A61B5/15003 , A61B5/150221 , A61B5/150992 , A61B5/154 , A61B5/150389 , A61B5/150473 , A61B5/150503 , A61B5/150572 , A61B5/150732 , A61B5/153
摘要： A fluid transfer system, including a channel member, adapted for connection between an arterial or venus catheter and an IV fluid administration system. The channel member includes a duct and an access port. An adapter including a recessed needle assembly is provided for mounting to the access port of the channel member. A syringe, IV tubing or an evacuated container may be mounted directly to the channel member via the adapter. Safety is substantially enhanced by recessing the needle assembly of the adapter.
摘要翻译：包括通道构件的流体输送系统，其适于在动脉或金星导管与IV液体给药系统之间连接。通道构件包括管道和入口。提供了一种包括凹入的针组件的适配器，用于安装到通道构件的进入口。注射器，IV管或抽真空的容器可以经由适配器直接安装到通道构件。通过使适配器的针头组件凹陷来大大提高安全性。

6. 发明授权

US5203771A Arterial/venous fluid transfer system 失效
标题翻译：动脉/静脉液体输送系统
公开(公告)号：US5203771A
公开(公告)日：1993-04-20
申请号：US821769
申请日：1992-05-18
申请人： Richard J. Melker , Gary J. Miller
发明人： Richard J. Melker , Gary J. Miller
IPC分类号： A61B5/15 , A61M39/00 , A61M39/02 , A61M39/04
CPC分类号： A61M39/04 , A61B5/15003 , A61B5/150221 , A61B5/150992 , A61B5/154 , A61B5/150389 , A61B5/150473 , A61B5/150503 , A61B5/150572 , A61B5/150732 , A61B5/153
摘要： A fluid transfer system, including a channel member, adapted for connection between an arterial or venus catheter and an IV fluid administration system. The channel member includes a duct and an access port. An adapter including a recessed needle assembly is provided for mounting to the access port of the channel member. A syringe, IV tubing or an evacuated container may be mounted directly to the channel member via the adapter. Safety is substantially enhanced by recessing the needle assembly of the adapter.
摘要翻译：包括通道构件的流体输送系统，其适于在动脉或金星导管与IV液体给药系统之间连接。通道构件包括管道和入口。提供了一种包括凹入的针组件的适配器，用于安装到通道构件的进入口。注射器，IV管或抽真空的容器可以经由适配器直接安装到通道构件。通过使适配器的针头组件凹陷来大大提高安全性。

7. 发明授权

US5158558A Needle-shielding fluid transfer device 失效
标题翻译：针式流体传动装置
公开(公告)号：US5158558A
公开(公告)日：1992-10-27
申请号：US510521
申请日：1990-04-18
申请人： Richard J. Melker , Gary J. Miller
发明人： Richard J. Melker , Gary J. Miller
IPC分类号： A61J1/00 , A61J1/20
CPC分类号： A61J1/2096 , A61J1/201 , Y10S604/905
摘要： A needle-shielding fluid transfer device for safely transferring fluid from a needle-bearing medical device to a separate container. The device includes a housing having a passage therethrough. At one end section of the housing, the passage has a relatively large diameter and the housing is adapted to easily accept and hold the needle-bearing medical device from which fluid is to be transferred. At a second end section, the housing is adapted to accept the container into which fluid is to be transferred. When a needle-bearing medical device is inserted into the passage at the first end section of the passage and a container is inserted into the second end section of the housing the needle of the needle-bearing medical device enters the container and fluid may be transferred. In one embodiment, the housing is split into two housing components to form a clamshell-like structure.
摘要翻译：一种用于将流体从针状医疗装置安全地传送到单独的容器的针式屏蔽流体输送装置。该装置包括具有穿过其中的通道的壳体。在壳体的一端部，通道具有相对较大的直径，并且壳体适于容易地接受和保持要从中传输流体的滚针式医疗装置。在第二端部处，壳体适于容纳流体要被传送到的容器。当将针轴承医疗装置插入通道的第一端部的通道中并且将容器插入到壳体的第二端部时，针状医疗装置的针进入容器并且可以转移流体。在一个实施例中，壳体被分成两个壳体部件以形成蛤壳状结构。

8. 发明授权

US10137245B2 Central site photoplethysmography, medication administration, and safety 有权
公开(公告)号：US10137245B2
公开(公告)日：2018-11-27
申请号：US13817156
申请日：2011-08-08
申请人： Richard J. Melker , Donn M. Dennis , Jeremy Melker , Mark Rice , Robert Hurley , Mark Gold , Richard Allen
发明人： Richard J. Melker , Donn M. Dennis , Jeremy Melker , Mark Rice , Robert Hurley , Mark Gold , Richard Allen
IPC分类号： A61M16/01 , A61M16/10 , A61M5/172 , A61M5/142 , A61B5/0205 , A61B5/1455 , A61M16/06 , A61M16/16 , G06F19/00 , A61M5/168 , A61B5/00 , A61B5/024 , A61B5/0402 , A61B5/08 , A61B5/083 , A61M16/00
摘要： A monitoring and control system, apparatus and method for safe administration, reduction or cessation of administration of at least on medication, fluid or both, which includes at least one Central Source Site (CSS) Photoplethysmography (PPG) sensor coupled to means for control of delivery of the at least one medication, fluid or both.

9. 发明授权

US09370634B2 Monitoring positive end expiratory pressure with photoplethysmography 有权
标题翻译：用光体积描记法监测呼气末正压
公开(公告)号：US09370634B2
公开(公告)日：2016-06-21
申请号：US14334114
申请日：2014-07-17
申请人： Richard J. Melker , Neil R. Euliano
发明人： Richard J. Melker , Neil R. Euliano
IPC分类号： A61B5/08 , A61M16/00 , A61B5/00 , A61M16/10 , A61B5/1455 , A61B5/107
CPC分类号： A61B5/4884 , A61B5/0205 , A61B5/02416 , A61B5/08 , A61B5/085 , A61B5/1073 , A61B5/14551 , A61B5/14552 , A61B5/411 , A61B5/4836 , A61B2560/0223 , A61M16/0069 , A61M16/1005 , A61M2205/3303 , A61M2205/3306 , A61M2205/502 , A61M2230/205
摘要： Provided according to embodiments of the invention are methods for monitoring the application of positive end expiratory pressure (PEEP) to an individual. Such methods include isolating a pulsatile arterial component (PAC) signal and a venous impedance component (VIC) signal of a PPG signal obtained from a central source site of the individual; monitoring the PAC signal, the VIC signal, or both, over time; and adjusting the level of PEEP based on the PAC signal, the VIC signal, or both.
摘要翻译：根据本发明的实施例提供的是用于监测对于个体的正端呼气压（PEEP）的应用的方法。这样的方法包括分离从个体的中央源位点获得的PPG信号的脉动动脉分量（PAC）信号和静脉阻抗分量（VIC）信号; 随着时间的推移监视PAC信号，VIC信号或两者; 并根据PAC信号，VIC信号或两者调整PEEP的电平。

10. 发明授权

US08755857B2 Optimized gas supply using photoplethysmography 有权
标题翻译：使用photoplethysmography优化供气
公开(公告)号：US08755857B2
公开(公告)日：2014-06-17
申请号：US11535295
申请日：2006-09-26
申请人： Richard J. Melker , A. Joseph Layon
发明人： Richard J. Melker , A. Joseph Layon
IPC分类号： A61B5/1455 , A61M16/00
CPC分类号： A61B5/0295 , A61B5/0205 , A61B5/02416 , A61B5/02427 , A61B5/0261 , A61B5/036 , A61B5/087 , A61B5/0873 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/4836 , A61B5/6819 , A61B5/682 , A61B5/6826 , A61B5/6829 , A61B5/7278 , A61B5/7282 , A61B2560/0276 , A61B2562/247 , A61M16/0003 , A61M16/0051 , A61M16/0057 , A61M16/021 , A61M16/0666 , A61M16/0672 , A61M16/08 , A61M16/20 , A61M2202/0208 , A61M2202/03 , A61M2205/3561 , A61M2205/3569 , A61M2210/0618 , A61M2210/0625 , A61M2210/0662 , A61M2230/06 , A61M2230/205 , A61M2230/30 , A61M2230/42 , A61M2230/432 , A61M2230/005 , A61M2202/0007
摘要： The present invention relates to optimized gas supply utilizing photoplethysmography. Flow rate, pressure or amount of gas adjusted as a function of blood oxygen saturation data, photoplethysmography signals, or both, obtained from the pulse oximeter probe.
摘要翻译：本发明涉及利用光电容积描记术优化的气体供应。流量，压力或气体量根据血氧饱和度数据，光电容积描记信号或两者从脉搏血氧计探头获得。

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