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1. 发明申请

US20060100480A1 Apparatus and methods for achieving endoluminal access 有权
标题翻译：用于实现腔内通路的装置和方法
公开(公告)号：US20060100480A1
公开(公告)日：2006-05-11
申请号：US11311999
申请日：2005-12-19
申请人： Richard Ewers , Boris Reydel , Eugene Chen , Vahid Saadat
发明人： Richard Ewers , Boris Reydel , Eugene Chen , Vahid Saadat
IPC分类号： A61B1/00
CPC分类号： A61B1/00149 , A61B1/00082 , A61B1/00147 , A61B1/31
摘要： The present invention provides methods and apparatus for pleating at least a portion of a patient's body lumen, such as the colon. Pleating is achieved via relative motion between an endoscope and a flexible conduit having an engagement element configured to reversibly engage the body lumen.
摘要翻译：本发明提供了用于打褶患者体腔（如结肠）的至少一部分的方法和装置。褶皱通过内窥镜和具有配置为可逆地接合体腔的接合元件的柔性导管之间的相对运动来实现。

2. 发明申请

US20050065536A1 Apparatus and methods for forming gastrointestinal tissue approximations 有权
标题翻译：用于形成胃肠组织近似的装置和方法
公开(公告)号：US20050065536A1
公开(公告)日：2005-03-24
申请号：US10992912
申请日：2004-11-18
申请人： Richard Ewers , Boris Reydel , Cang Lam , Eugene Chen , Brent Seybold , Rodney Brenneman , Vahid Saadat
发明人： Richard Ewers , Boris Reydel , Cang Lam , Eugene Chen , Brent Seybold , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/28 , A61B17/34 , A61B17/08
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B17/0644 , A61B17/29 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/061 , A61B2017/3445 , A61B2017/3488
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point, moving the first tissue contact point from a position initially distal to a second tissue contact point to a position proximal of the second contact point to form a tissue fold, and extending an anchor assembly through the tissue fold near the second tissue contact point.
摘要翻译：提供了设备和方法，用于通过在第一组织接触点处接合组织来形成胃肠组织折叠，将第一组织接触点从最初远端到第二组织接触点的位置移动到第二接触点的近侧的位置，以形成组织折叠，并且使锚固组件穿过第二组织接触点附近的组织褶皱延伸。

3. 发明申请

US20050119671A1 Apparatus and methods for endoscopic suturing 有权
标题翻译：用于内窥镜缝合的装置和方法
公开(公告)号：US20050119671A1
公开(公告)日：2005-06-02
申请号：US10986461
申请日：2004-11-10
申请人： Boris Reydel , Cang Lam , Richard Ewers , Rodney Brenneman , Vahid Saadat
发明人： Boris Reydel , Cang Lam , Richard Ewers , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B20060101 , A61B17/00 , A61B17/04 , A61B17/08 , A61B17/28 , A61B19/00
CPC分类号： A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/0625 , A61B2017/00353 , A61B2017/0417 , A61B2017/2927 , A61B2090/3614
摘要： Apparatus & methods for endoscopic suturing are described herein. A distal tip of the endoscopic device engages the tissue and then approximates the engaged tissue to form a tissue fold. A needle body positioned within a flexible catheter is deployed into or through the newly created tissue fold where it is then detached or released from the endoscopic device. The needle body has a length of suture which depends therefrom and can be used to secure the tissue fold. The entire endoscopic device or its tissue engaging assembly can then be rotated relative to the tissue fold while maintaining engagement with the tissue to maneuver the flexible catheter to the opposing side of the penetrated tissue fold. This procedure can be repeated any number of times to create an interrupted, continuous, or running suture to secure the tissue fold.
摘要翻译：本文描述了用于内窥镜缝合的装置和方法。内窥镜装置的远侧末端接合组织，然后近似接合的组织以形成组织折叠。定位在柔性导管内的针体部署在新产生的组织折叠中或穿过其中，然后将其从内窥镜装置分离或释放。针体具有一定长度的缝合线，该缝合线依赖于其而可用于固定组织折叠。然后，整个内窥镜装置或其组织接合组件可以相对于组织折叠旋转，同时保持与组织的接合，以将柔性导管操纵到穿透的组织折叠的相对侧。该过程可以重复任意次数以产生中断的，连续的或运行的缝线来固定组织折叠。

4. 发明授权

US08066719B2 Apparatus and methods for forming gastrointestinal tissue approximations 有权
标题翻译：用于形成胃肠组织近似的装置和方法
公开(公告)号：US08066719B2
公开(公告)日：2011-11-29
申请号：US10992912
申请日：2004-11-18
申请人： Richard C. Ewers , Boris Reydel , Cang C. Lam , Eugene Chen , Brent D. Seybold , Rodney Brenneman , Vahid Saadat
发明人： Richard C. Ewers , Boris Reydel , Cang C. Lam , Eugene Chen , Brent D. Seybold , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B17/10 , A61B17/32
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B17/0644 , A61B17/29 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/061 , A61B2017/3445 , A61B2017/3488
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point, moving the first tissue contact point from a position initially distal to a second tissue contact point to a position proximal of the second contact point to form a tissue fold, and extending an anchor assembly through the tissue fold near the second tissue contact point.
摘要翻译：提供了设备和方法，用于通过在第一组织接触点处接合组织来形成胃肠组织折叠，将第一组织接触点从最初远端到第二组织接触点的位置移动到第二接触点的近侧的位置，以形成组织折叠，并且使锚固组件穿过第二组织接触点附近的组织褶皱延伸。

5. 发明申请

US20050137455A1 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 审中-公开
标题翻译：形状可锁定装置和方法，用于通过不支持的解剖结构推进器械
公开(公告)号：US20050137455A1
公开(公告)日：2005-06-23
申请号：US10888439
申请日：2004-07-08
申请人： Richard Ewers , Vahid Saadat , Eugene Chen
发明人： Richard Ewers , Vahid Saadat , Eugene Chen
IPC分类号： A61B1/005 , A61B1/01 , A61B1/31 , A61B1/32 , A61B1/00
CPC分类号： A61B1/0052 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00135 , A61B1/0055 , A61B1/0057 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic of therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.
摘要翻译：提供了设备和方法，用于将治疗仪器的诊断放置并行进在曲折或无支撑的解剖结构的中空身体器官中，包括手柄，外套管，具有无创伤尖端的远侧区域。外套管可以从手柄移除，并且具有相对于把手以一定角度设置的纵向轴线。外套管可以选择性地加强，以减少由诊断或治疗仪器的前进引起的器官膨胀。远端区域允许由诊断或治疗仪器的偏转引起的外套管的被动转向，而无创伤的尖端在操纵诊断或治疗仪器期间防止器官的壁被卡住或夹住。

6. 发明申请

US20050113640A1 Endoluminal tool deployment system 审中-公开
标题翻译：腔内工具部署系统
公开(公告)号：US20050113640A1
公开(公告)日：2005-05-26
申请号：US10990559
申请日：2004-11-16
申请人： Vahid Saadat , Richard Ewers , Eugene Chen , David Miller
发明人： Vahid Saadat , Richard Ewers , Eugene Chen , David Miller
IPC分类号： A61B1/005 , A61B1/018 , A61B1/313 , A61B17/34
CPC分类号： A61B17/00234 , A61B1/0055 , A61B1/0057 , A61B1/018 , A61B1/313 , A61B2017/003 , A61B2017/00323 , A61B2017/00349 , A61B2017/2906 , A61B2017/3445 , A61B2090/306 , A61B2090/508 , A61M25/0043 , A61M25/0105 , A61M25/0147 , A61M2025/0096
摘要： Systems, devices and methods are provided for endoscopic procedures involving tissue manipulations beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body having a scope therethrough and at least one steerable tool arm which extends from the distal end of the main body. In preferred embodiments, the system includes two tool arms, each arm steerable to form a curve laterally outward which then bends laterally inward so that the arms form an angular shape. In addition, end effectors extend from the distal ends of each tool arm for use in manipulation of tissue. The angular shape brings the end effectors together in view of the scope for cooperative movements which are continuously visible by the surgeon. In addition, the tool arms may be steerable in any additional direction and may be rotateable to allow grasping, elevation and more complex manipulation of tissue.
摘要翻译：提供的系统，装置和方法用于内窥镜手术，其涉及组织操作超出传统内窥镜仪器的能力。系统的实施例包括具有穿过其中的一个细长主体和从该主体的远端延伸的至少一个可操纵的工具臂。在优选实施例中，系统包括两个工具臂，每个臂可转向以横向向外形成曲线，然后横向向内弯曲，使得臂形成角形。另外，末端执行器从每个工具臂的远端延伸以用于组织的操作。考虑到外科医生连续可见的协作运动的范围，角形状使末端执行器结合在一起。此外，工具臂可以在任何附加方向上是可操纵的并且可以是可旋转的，以允许组织的抓握，升高和更复杂的操纵。

7. 发明申请

US20050065397A1 Endoluminal tool deployment system 有权
公开(公告)号：US20050065397A1
公开(公告)日：2005-03-24
申请号：US10991118
申请日：2004-11-16
申请人： Vahid Saadat , Richard Ewers , Eugene Chen , David Miller
发明人： Vahid Saadat , Richard Ewers , Eugene Chen , David Miller
IPC分类号： A61B1/005 , A61B1/018 , A61B1/313 , A61B17/34 , A61B1/00
CPC分类号： A61B17/00234 , A61B1/0055 , A61B1/0057 , A61B1/018 , A61B1/313 , A61B2017/003 , A61B2017/00323 , A61B2017/00349 , A61B2017/2906 , A61B2017/3445 , A61B2090/306 , A61B2090/508 , A61M25/0043 , A61M25/0105 , A61M25/0147 , A61M2025/0096
摘要： Systems, devices and methods are provided for endoscopic procedures involving tissue manipulations beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body having a scope therethrough and at least one steerable tool arm which extends from the distal end of the main body. In preferred embodiments, the system includes two tool arms, each arm steerable to form a curve laterally outward which then bends laterally inward so that the arms form an angular shape. In addition, end effectors extend from the distal ends of each tool arm for use in manipulation of tissue. The angular shape brings the end effectors together in view of the scope for cooperative movements which are continuously visible by the surgeon. In addition, the tool arms may be steerable in any additional direction and may be rotateable to allow grasping, elevation and more complex manipulation of tissue.

8. 发明申请

US20050137456A1 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 有权
公开(公告)号：US20050137456A1
公开(公告)日：2005-06-23
申请号：US10888531
申请日：2004-07-08
申请人： Vahid Saadat , Richard Ewers , Eugene Chen
发明人： Vahid Saadat , Richard Ewers , Eugene Chen
IPC分类号： A61B1/005 , A61B1/008 , A61B1/01 , A61B1/31 , A61B1/32 , A61B1/00
CPC分类号： A61B1/0052 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00105 , A61B1/00135 , A61B1/00154 , A61B1/0055 , A61B1/0057 , A61B1/0058 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

9. 发明申请

US20050137454A1 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 审中-公开
公开(公告)号：US20050137454A1
公开(公告)日：2005-06-23
申请号：US10888083
申请日：2004-07-08
申请人： Vahid Saadat , Richard Ewers , Eugene Chen
发明人： Vahid Saadat , Richard Ewers , Eugene Chen
IPC分类号： A61B1/005 , A61B1/01 , A61B1/31 , A61B1/32 , A61B1/00 , A61B1/04
CPC分类号： A61B1/0052 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00135 , A61B1/0055 , A61B1/0057 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

10. 发明申请

US20060287666A1 Apparatus and methods for endoluminal advancement 审中-公开
标题翻译：用于腔内推进的装置和方法
公开(公告)号：US20060287666A1
公开(公告)日：2006-12-21
申请号：US11154168
申请日：2005-06-15
申请人： Vahid Saadat , Eugene Chen , Tung Le , Tracy Maahs , Richard Ewers , John Cox , Chris Rothe
发明人： Vahid Saadat , Eugene Chen , Tung Le , Tracy Maahs , Richard Ewers , John Cox , Chris Rothe
IPC分类号： A61M29/00
CPC分类号： A61M25/1011 , A61B2017/22068 , A61B2017/22069 , A61M2025/1015 , A61M2025/1052
摘要： Apparatus and methods for endoluminal advancement are described herein. A shape-lockable tissue anchoring assembly generally has an elongate body, a handle assembly, and an anchoring assembly positioned at or proximal to a distal tip of the elongate body. A distal portion of the elongate body may optionally be steerable or curvable. The anchoring assembly may include various expandable or projecting anchoring features to contact and retain tissue relative to the elongate body such that pleated tissue is temporarily immobile relative to the elongate body. This anchoring can be actuated simultaneously with or independently from shape-locking of elongate body. The anchoring assembly can be actuated simultaneously with the shape-locking of the elongate body. Alternatively, the steerable distal portion of the elongate body can be angled against the pleated tissue to retain it while the endoscope is advanced relative to the pleated tissue.
摘要翻译：本文描述了腔内前进的装置和方法。可锁定形状的组织锚固组件通常具有细长主体，手柄组件和定位在细长主体的远侧末端处或近侧的锚固组件。细长主体的远端部分可以可选地是可操纵的或可调节的。锚定组件可以包括各种可膨胀或突出的锚固特征，以相对于细长体接触和保持组织，使得褶皱组织相对于细长体临时固定不动。这种锚固可以与细长体的形状锁定同时或独立地致动。锚固组件可以与细长体的形状锁定同时致动。或者，细长主体的可转向远端部分可以相对于打褶组织成角度，以在内窥镜相对于打褶组织前进时保持它。

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