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1. 发明申请

US20060287666A1 Apparatus and methods for endoluminal advancement 审中-公开
标题翻译：用于腔内推进的装置和方法
公开(公告)号：US20060287666A1
公开(公告)日：2006-12-21
申请号：US11154168
申请日：2005-06-15
申请人： Vahid Saadat , Eugene Chen , Tung Le , Tracy Maahs , Richard Ewers , John Cox , Chris Rothe
发明人： Vahid Saadat , Eugene Chen , Tung Le , Tracy Maahs , Richard Ewers , John Cox , Chris Rothe
IPC分类号： A61M29/00
CPC分类号： A61M25/1011 , A61B2017/22068 , A61B2017/22069 , A61M2025/1015 , A61M2025/1052
摘要： Apparatus and methods for endoluminal advancement are described herein. A shape-lockable tissue anchoring assembly generally has an elongate body, a handle assembly, and an anchoring assembly positioned at or proximal to a distal tip of the elongate body. A distal portion of the elongate body may optionally be steerable or curvable. The anchoring assembly may include various expandable or projecting anchoring features to contact and retain tissue relative to the elongate body such that pleated tissue is temporarily immobile relative to the elongate body. This anchoring can be actuated simultaneously with or independently from shape-locking of elongate body. The anchoring assembly can be actuated simultaneously with the shape-locking of the elongate body. Alternatively, the steerable distal portion of the elongate body can be angled against the pleated tissue to retain it while the endoscope is advanced relative to the pleated tissue.
摘要翻译：本文描述了腔内前进的装置和方法。可锁定形状的组织锚固组件通常具有细长主体，手柄组件和定位在细长主体的远侧末端处或近侧的锚固组件。细长主体的远端部分可以可选地是可操纵的或可调节的。锚定组件可以包括各种可膨胀或突出的锚固特征，以相对于细长体接触和保持组织，使得褶皱组织相对于细长体临时固定不动。这种锚固可以与细长体的形状锁定同时或独立地致动。锚固组件可以与细长体的形状锁定同时致动。或者，细长主体的可转向远端部分可以相对于打褶组织成角度，以在内窥镜相对于打褶组织前进时保持它。

2. 发明申请

US20050251202A1 Interlocking tissue anchor apparatus and methods 有权
标题翻译：联锁组织锚装置和方法
公开(公告)号：US20050251202A1
公开(公告)日：2005-11-10
申请号：US10955244
申请日：2004-09-30
申请人： Richard Ewers , Tracy Maahs , Cang Lam , Vahid Saadat , Chris Rothe
发明人： Richard Ewers , Tracy Maahs , Cang Lam , Vahid Saadat , Chris Rothe
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Interlocking tissue anchor apparatus and methods are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. Anchor assemblies can be delivered via the tissue manipulation assembly into or through the tissue. The anchors can incorporate various temporary interlocking features or spacing elements between one another to ensure that an anchor is not prematurely ejected from the needle assembly. This allows the anchor assembly to be advanced distally as well as withdrawn proximally within a deployment sheath while avoiding inadvertently ejecting an anchor.
摘要翻译：本文描述了联锁组织锚装置和方法。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。锚固组件可以经由组织操纵组件输送到组织或穿过组织。锚固件可以在彼此之间结合各种临时互锁特征或间隔元件，以确保锚不会从针组件过早地弹出。这允许锚固组件在部署护套内远端地向远侧推进，同时避免无意中弹出锚固件。

3. 发明申请

US20060178560A1 Endoluminal tool deployment system 审中-公开
标题翻译：腔内工具部署系统
公开(公告)号：US20060178560A1
公开(公告)日：2006-08-10
申请号：US11400120
申请日：2006-04-07
申请人： Vahid Saadat , Chris Rothe , Richard Ewers , Tracy Maahs , Kenneth Michlitsch
发明人： Vahid Saadat , Chris Rothe , Richard Ewers , Tracy Maahs , Kenneth Michlitsch
IPC分类号： A61B1/008
CPC分类号： A61B1/0055 , A61B1/018 , A61B1/2736 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/29 , A61B2017/00296 , A61B2017/003 , A61B2017/00323 , A61B2017/00827 , A61B2017/0406 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/06052 , A61B2017/2905 , A61B2017/2906 , A61B2017/306
摘要： Systems, devices and methods for endoscopic procedures are provided involving accessing and manipulating tissues beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body which has one or more independently shape-lockable sections and a variety of instruments which are either built in to the main body or advanceable through lumens which extend through the main body. Such instruments may include scopes, suction instruments, aspiration instruments, tool arms, plicators, needles, graspers, and cutters, to name a few. The ability to steer and shapelock specific sections of the main body enables access to target locations which are typically challenging to reach and provides a stabilized platform to perform a desired procedure at the target location.
摘要翻译：提供用于内窥镜手术的系统，装置和方法，其涉及访问和操纵超出传统内窥镜仪器能力的组织。该系统的实施例包括具有一个或多个独立形状可锁定部分的细长主体以及内置于主体中或通过延伸穿过主体的腔的可前进的各种仪器。这样的仪器可以包括示波器，抽吸仪器，抽吸仪器，工具臂，矫正器，针，抓取器和切割器等等。转向和塑造主体的特定部分的能力使得能够访问通常具有挑战性的目标位置，并且提供稳定的平台以在目标位置执行期望的过程。

4. 发明申请

US20060058582A1 Disposable shapelocking system 审中-公开
标题翻译：一次性形状锁定系统
公开(公告)号：US20060058582A1
公开(公告)日：2006-03-16
申请号：US11238298
申请日：2005-09-28
申请人： Tracy Maahs , Vahid Saadat , Chris Rothe , Tung Le
发明人： Tracy Maahs , Vahid Saadat , Chris Rothe , Tung Le
IPC分类号： A61B1/00
CPC分类号： A61B1/00154 , A61B1/0055 , A61B17/3421 , A61B2017/00314 , A61B2017/345
摘要： Disposable shapelocking systems are disclosed herein. A shapelock assembly generally comprises an elongate body defining at least one lumen therethrough for advancement of an endoscope or other endoscopic instruments therethrough. A handle assembly can be actuated to compress nested links against one another to transition the elongate body from a flexible state to a rigid shape-locked state. One or more of the nested links can be made from a particular thermoplastic either alone or in combination with one or more reinforcing structures. Such structures can include a reinforcing ring integrated with the link on an inner, outer, or lower surface of the link. Alternatively, the link can be coated or layered to enhance its strength. Additionally, different portions of the shapelock body can be made from different types of links depending upon the loads imparted upon the various portions of the shapelock body.
摘要翻译：本文公开了一次性形状锁定系统。形状锁定组件通常包括限定穿过其中的至少一个内腔的细长主体，用于使内窥镜或其它内窥镜器械从其中前进。手柄组件可以被致动以将嵌套的链节相互压缩以将细长主体从柔性状态转换到刚性形状锁定状态。嵌套链接中的一个或多个可以单独地或与一个或多个加强结构组合地由特定的热塑性材料制成。这种结构可以包括与连杆的内，外或下表面上的连杆成一体的加强环。或者，链接可以被涂覆或分层以提高其强度。此外，形状锁体的不同部分可以根据施加在形状锁体的各个部分上的载荷从不同类型的连杆制成。

5. 发明申请

US20060189845A1 Methods and apparaus for off-axis visualization 有权
标题翻译：离轴可视化的方法和应用
公开(公告)号：US20060189845A1
公开(公告)日：2006-08-24
申请号：US11365088
申请日：2006-02-28
申请人： Tracy Maahs , Richard Ewers , Arvin Chang , Chris Rothe , Eugene Chen , Marvin Elmer , Gilbert Madrid , Kabir Gambhir
发明人： Tracy Maahs , Richard Ewers , Arvin Chang , Chris Rothe , Eugene Chen , Marvin Elmer , Gilbert Madrid , Kabir Gambhir
IPC分类号： A61B1/00
CPC分类号： A61B1/00179 , A61B1/0008 , A61B1/00183 , A61B1/0051 , A61B1/018 , A61B1/04
摘要： Methods and apparatus for off-axis visualization are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.
摘要翻译：本文描述了用于离轴可视化的方法和装置。公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接离轴并且操纵感兴趣的组织区域。

6. 发明授权

US08512229B2 Method and apparatus for obtaining endoluminal access 有权
标题翻译：用于获得腔内通路的方法和装置
公开(公告)号：US08512229B2
公开(公告)日：2013-08-20
申请号：US10824936
申请日：2004-04-14
申请人： Vahid Saadat , Desmond Birkett , Chris Rothe , Tracy Maahs
发明人： Vahid Saadat , Desmond Birkett , Chris Rothe , Tracy Maahs
IPC分类号： A61B1/00
CPC分类号： A61B1/04 , A61B1/0008 , A61B1/00183 , A61B1/00193 , A61B1/018
摘要： The present invention provides methods and apparatus for obtaining endoluminal access. An elongate body is configured for insertion within a body lumen, conduit, organ, orifice or passageway, the elongate body having a working axis and a distal region, and an articulating element disposed near the distal region, the articulating element configured to articulate off-axis from the working axis of the elongate body. Methods of using apparatus of the present invention are also provided.
摘要翻译：本发明提供了获得腔内通路的方法和装置。细长体构造成用于插入体腔，导管，器官，孔或通道中，细长体具有工作轴线和远端区域，以及设置在远侧区域附近的关节元件，所述关节元件构造成关闭，轴从细长体的工作轴线。还提供了使用本发明装置的方法。

7. 发明申请

US20050234296A1 Method and apparatus for obtaining endoluminal access 有权
标题翻译：用于获得腔内通路的方法和装置
公开(公告)号：US20050234296A1
公开(公告)日：2005-10-20
申请号：US10824936
申请日：2004-04-14
申请人： Vahid Saadat , Desmond Birkett , Chris Rothe , Tracy Maahs
发明人： Vahid Saadat , Desmond Birkett , Chris Rothe , Tracy Maahs
IPC分类号： A61B1/00 , A61B1/01 , A61B1/018 , A61B1/04
CPC分类号： A61B1/04 , A61B1/0008 , A61B1/00183 , A61B1/00193 , A61B1/018
摘要： The present invention provides methods and apparatus for obtaining endoluminal access. An elongate body is configured for insertion within a body lumen, conduit, organ, orifice or passageway, the elongate body having a working axis and a distal region, and an articulating element disposed near the distal region, the articulating element configured to articulate off-axis from the working axis of the elongate body. Methods of using apparatus of the present invention are also provided.
摘要翻译：本发明提供了获得腔内通路的方法和装置。细长体构造成用于插入体腔，导管，器官，孔或通道中，细长体具有工作轴线和远端区域，以及设置在远侧区域附近的关节元件，所述关节元件构造成关闭，轴从细长体的工作轴线。还提供了使用本发明装置的方法。

8. 发明申请

US20050251162A1 Apparatus and methods for manipulating and securing tissue 有权
标题翻译：用于操纵和固定组织的装置和方法
公开(公告)号：US20050251162A1
公开(公告)日：2005-11-10
申请号：US10955245
申请日：2004-09-29
申请人： Chris Rothe , Richard Ewers , Cang Lam , Vahid Saadat , Kenneth Michlitsch
发明人： Chris Rothe , Richard Ewers , Cang Lam , Vahid Saadat , Kenneth Michlitsch
IPC分类号： A61B1/00 , A61B17/00 , A61B17/04 , A61B17/06 , A61B17/08 , A61B17/28 , A61B17/34 , A61B19/00
CPC分类号： A61B1/0014 , A61B17/0401 , A61B17/06066 , A61B17/29 , A61B17/295 , A61B2017/00867 , A61B2017/00876 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0496 , A61B2017/06052 , A61B2017/06076 , A61B2017/3488 , A61B2090/037
摘要： Apparatus and methods for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置和方法。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，位于所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

9. 发明申请

US20050251161A1 Needle assembly for tissue manipulation 有权
标题翻译：用于组织操作的针组件
公开(公告)号：US20050251161A1
公开(公告)日：2005-11-10
申请号：US10955243
申请日：2004-09-30
申请人： Vahid Saadat , Chris Rothe , Richard Ewers
发明人： Vahid Saadat , Chris Rothe , Richard Ewers
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/29 , A61B2017/00349 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Needle assemblies for tissue manipulation are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. A needle deployment assembly is deployable through the tissue manipulation assembly via a handle assembly, through the tubular member, and into or through tissue. An elongate pusher is translationally disposed within a sheath of the needle deployment assembly and can be urged distally for deploying an anchor assembly from the sheath distal end. The anchor assembly is positioned distally of the pusher within the sheath.
摘要翻译：用于组织操作的针组件在本文中描述。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，位于所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。针部署组件可经由手柄组件穿过组织操纵组件展开，穿过管状构件，并且进入或穿过组织。细长的推动器平移地设置在针展开组件的护套内，并且可以向远侧推动以从护套远端展开锚固组件。锚固组件位于鞘内的推动器的远侧。

10. 发明申请

US20050250986A1 Removable apparatus and methods for manipulating and securing tissue 审中-公开
公开(公告)号：US20050250986A1
公开(公告)日：2005-11-10
申请号：US11002404
申请日：2004-12-01
申请人： Chris Rothe , Richard Ewers , Vahid Saadat , Cang Lam
发明人： Chris Rothe , Richard Ewers , Vahid Saadat , Cang Lam
IPC分类号： A61B1/00 , A61B17/00 , A61B17/04 , A61B17/06 , A61B17/08 , A61B17/28 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0401 , A61B1/0014 , A61B17/06066 , A61B17/29 , A61B17/295 , A61B2017/00867 , A61B2017/00876 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0496 , A61B2017/06052 , A61B2017/06076 , A61B2017/3488 , A61B2090/037
摘要： Removable apparatus and methods for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have tissue stabilizing members adapted to stabilize tissue therebetween, an engagement member slidably disposed through the stabilizing members and having a distal end adapted to engage tissue, and a delivery tube pivotable about the tissue stabilizing members. The tissue manipulation assembly optionally may be configured for removable attachment to an endoscope.

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