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1. 发明申请

US20080027483A1 Implantable devices for controlling the size and shape of an anatomical structure or lumen 有权
标题翻译：用于控制解剖结构或内腔的尺寸和形状的可植入装置
公开(公告)号：US20080027483A1
公开(公告)日：2008-01-31
申请号：US11802264
申请日：2007-05-21
申请人： Richard Cartledge , Leonard Lee , James Fann , Josef Friedmann , James Green
发明人： Richard Cartledge , Leonard Lee , James Fann , Josef Friedmann , James Green
IPC分类号： A61B17/08 , A61B17/00 , A61B17/58 , A61B5/00
CPC分类号： A61F2/2442 , A61B5/061 , A61B5/6885 , A61B6/12 , A61B17/00234 , A61B17/0644 , A61B17/068 , A61B2017/00243 , A61B2017/00455 , A61B2017/00783 , A61B2017/0496 , A61B2017/0641 , A61B2090/062 , A61F2/0031 , A61F2/2445 , A61F2/2448 , A61F2/2466 , A61F2002/30537 , A61F2250/0004 , A61F2250/0029
摘要： An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.
摘要翻译：用于控制内部解剖通道的尺寸的可植入装置系统校正由太大或太小的结构腔引起的生理功能障碍。公开了可植入装置，其采用各种用于调节和维持它们所连接的孔的尺寸的机构。系统允许使用微创程序植入植入物，并允许在原位解剖液恢复正常流动之后对植入物的尺寸进行最终调整。

2. 发明申请

US20070016287A1 Methods and apparatus for controlling the internal circumference of an anatomic orifice or lumen 有权
标题翻译：用于控制解剖孔或内腔内周的方法和装置
公开(公告)号：US20070016287A1
公开(公告)日：2007-01-18
申请号：US11449139
申请日：2006-06-07
申请人： Richard Cartledge , Leonard Lee , James Fann
发明人： Richard Cartledge , Leonard Lee , James Fann
IPC分类号： A61F2/24 , A61F2/02
CPC分类号： A61F2/2445 , A61F2/2448 , A61F2/2466 , A61F2250/0004
摘要： An implantable device is provided for controlling shape and/or size of an anatomical structure or lumen. The implantable device has an adjustable member configured to adjust the dimensions of the implantable device. The implantable device is housed in a catheter and insertable from a minimally invasive surgical entry. An adjustment tool actuates the adjustable member and provide for adjustment before, during or after the anatomical structure or lumen resumes near normal to normal physiologic function.
摘要翻译：提供了一种用于控制解剖结构或内腔的形状和/或尺寸的可植入装置。可植入装置具有被配置成调节可植入装置的尺寸的可调部件。可植入装置容纳在导管中并可从微创手术入口插入。调节工具致动可调节构件，并在解剖结构或腔内恢复正常生理功能正常之前，期间或之后进行调节。

3. 发明申请

US20060241748A1 Methods and apparatus for controlling the internal circumference of an anatomic orifice or lumen 有权
标题翻译：用于控制解剖孔或内腔内周的方法和装置
公开(公告)号：US20060241748A1
公开(公告)日：2006-10-26
申请号：US11390984
申请日：2006-03-27
申请人： Leonard Lee , James Fann , Richard Cartledge
发明人： Leonard Lee , James Fann , Richard Cartledge
IPC分类号： A61F2/24 , A61F2/04
CPC分类号： A61F2/2445 , A61B17/12013 , A61B2017/086 , A61F2/2442 , A61F2/2466 , A61F2/2472 , A61F2210/0014 , A61F2220/0016 , A61F2220/0025 , A61F2220/0075 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0095 , A61F2250/001 , A61F2250/0082
摘要： An implantable device is provided for controlling at least one of shape and size of an anatomical structure or lumen. An implantable device has an adjustable member configured to adjust the dimensions of the implantable device. An adjustment tool is configured to actuate the adjustable member and provide for adjustment before, during and after the anatomical structure or lumen resumes near normal to normal physiologic function.
摘要翻译：提供了一种用于控制解剖结构或内腔的形状和尺寸中的至少一个的可植入装置。可植入装置具有被配置为调节可植入装置的尺寸的可调部件。调整工具被配置为致动可调节构件，并且在解剖结构或管腔在正常生理功能附近恢复之前，期间和之后提供调节。

4. 发明申请

US20050021057A1 Leaflet structuring 有权
标题翻译：小册子结构
公开(公告)号：US20050021057A1
公开(公告)日：2005-01-27
申请号：US10927589
申请日：2004-08-25
申请人： Frederick St. Goar , James Fann , Mark Deem , Hanson Gifford , Martin Dieck , Brian Martin , Sylvia Fan , Eric Goldfarb , Kent Dell , Ferolyn Powell
发明人： Frederick St. Goar , James Fann , Mark Deem , Hanson Gifford , Martin Dieck , Brian Martin , Sylvia Fan , Eric Goldfarb , Kent Dell , Ferolyn Powell
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/12 , A61B17/122 , A61B17/128 , A61F2/24
CPC分类号： A61B17/00234 , A61B8/10 , A61B17/04 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0625 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/07207 , A61B17/08 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00783 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/045 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06057 , A61B2017/06076 , A61B2017/061 , A61B2017/06171 , A61B2017/0641 , A61B2017/0649 , A61B2017/088 , A61B2017/2926 , A61B2018/00291 , A61F2/2445 , A61F2/2457
摘要： The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.
摘要翻译：提供的方法，装置和系统用于执行心脏中房室结和其他心脏瓣膜的血管内修复。房室瓣，特别是二尖瓣的反流可以通过修改选自瓣膜小叶，瓣膜环，瓣膜腱索和乳头肌的组织结构来修复。这些结构可以通过使用引入心脏室的介入工具通过缝合，缝合，痉挛或缩短来改变。优选地，组织结构将在永久性修饰之前临时修改。例如，相对的瓣叶可以在永久性附着之前被暂时抓住并保持就位。

5. 发明申请

US20050033446A1 Methods and apparatus for cardiac valve repair 审中-公开
标题翻译：心脏瓣膜修复方法及装置
公开(公告)号：US20050033446A1
公开(公告)日：2005-02-10
申请号：US10820581
申请日：2004-04-07
申请人： Mark Deem , Hanson Gifford , Martin Dieck , James Fann , Frederick St. Goar
发明人： Mark Deem , Hanson Gifford , Martin Dieck , James Fann , Frederick St. Goar
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/12 , A61B17/122 , A61B17/128 , A61F2/24
CPC分类号： A61B17/00234 , A61B8/10 , A61B17/04 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0625 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/07207 , A61B17/08 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00783 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/045 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06057 , A61B2017/06076 , A61B2017/061 , A61B2017/06171 , A61B2017/0641 , A61B2017/0649 , A61B2017/088 , A61B2017/2926 , A61B2018/00291 , A61F2/2445 , A61F2/2457
摘要： The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.
摘要翻译：提供的方法，装置和系统用于执行心脏中房室结和其他心脏瓣膜的血管内修复。房室瓣，特别是二尖瓣的反流可以通过修改选自瓣膜小叶，瓣膜环，瓣膜腱索和乳头肌的组织结构来修复。这些结构可以通过使用引入心脏室的介入工具通过缝合，缝合，痉挛或缩短来改变。优选地，组织结构将在永久性修饰之前临时修改。例如，相对的瓣叶可以在永久性附着之前被暂时抓住并保持就位。

6. 发明申请

US20070038293A1 Device and methods for endoscopic annuloplasty 审中-公开
标题翻译：内窥镜瓣环成形术的装置和方法
公开(公告)号：US20070038293A1
公开(公告)日：2007-02-15
申请号：US11411441
申请日：2006-04-25
申请人： Frederick St.Goar , James Fann , Mark Deem , Hanson Gifford , Martin Dieck , Brian Martin , Sylvia Fan , Eric Goldfarb , Kent Dell , Ferolyn Powell
发明人： Frederick St.Goar , James Fann , Mark Deem , Hanson Gifford , Martin Dieck , Brian Martin , Sylvia Fan , Eric Goldfarb , Kent Dell , Ferolyn Powell
IPC分类号： A61F2/24
CPC分类号： A61B17/00234 , A61B17/0487 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/07207 , A61B17/08 , A61B17/29 , A61B17/2909 , A61B2017/00243 , A61B2017/00783 , A61B2017/00867 , A61B2017/0409 , A61B2017/0417 , A61B2017/045 , A61B2017/0474 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06076 , A61B2017/06171 , A61B2017/0641 , A61B2017/0649 , A61B2017/088 , A61B2017/2905 , A61B2017/2927 , A61B2017/2932 , A61B2017/2944 , A61B2017/2946 , A61B2017/306 , A61F2/2427 , A61F2/2445 , A61F2/2466 , A61M25/0147 , A61M25/0152
摘要： The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. The tissue structures can be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment. In one aspect, a structure is deployed in a gutter region of the valve annulus to modify the shape of the valve.
摘要翻译：提供的方法，装置和系统用于执行心脏中房室结和其他心脏瓣膜的血管内修复。房室瓣，特别是二尖瓣的反流可以通过修改选自瓣膜小叶，瓣膜环，瓣膜腱索和乳头肌的组织结构来修复。这些结构可以通过使用引入心脏室的介入工具通过缝合，缝合，痉挛或缩短来改变。组织结构可以在永久性修改之前暂时修改。例如，相对的瓣叶可以在永久性附着之前被暂时抓住并保持就位。在一个方面，结构被布置在阀环的沟槽区域中以改变阀的形状。

7. 发明申请

US20060106405A1 Systems and methods for delivering fastener to opposed tissue structures 审中-公开
标题翻译：将紧固件递送到相对的组织结构的系统和方法
公开(公告)号：US20060106405A1
公开(公告)日：2006-05-18
申请号：US11274791
申请日：2005-11-15
申请人： James Fann , Hanson Gifford
发明人： James Fann , Hanson Gifford
IPC分类号： A61B17/10
CPC分类号： A61B17/11 , A61B17/0644 , A61B17/1285 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1103 , A61B2017/1107 , A61B2017/1135
摘要： Flexible clips which are transported over a solid needle or through a hollow needle and methods of use thereof are described for tissue approximation and attachment and for joining a graft vessel to a target vessel. The tissue approximation or anastomosis clip includes a highly flexible or elastic material wrapped around and transported on the outside of a solid needle. Another embodiment is a flexible or composite clip which is transported within a hollow needle. The distal end of the clips has a tapered configuration to minimize resistance and facilitate tissue penetration. After placement of the clip in the desired location, the solid or hollow needle is withdrawn resulting in coiling or contraction of the clip thus approximating the tissue and securing the clip. Multiple clips can be loaded in the deployment device which is calibrated to deploy and secure one clip at a time. An additional embodiment is a needle point attached to a clip that overrides a solid shaft. Deployment is by pushing or displacing the clip portion from the shaft. A plurality of these needle-clips may be oriented on a circular ring which permits rapid clip deployment and tissue approximation, such as for anastomosis, and methods for subsequent ring removal or dismantling.
摘要翻译：描述了通过固体针或通过中空针运送的柔性夹子及其使用方法用于组织近似和附接并用于将移植血管连接到靶容器。组织近似或吻合夹包括在固体针的外侧缠绕并运输的高度柔性或弹性的材料。另一个实施例是在中空针内输送的柔性或复合夹子。夹子的远端具有锥形构型以最小化阻力并促进组织穿透。在将夹子放置在所需位置之后，将固体或中空针抽出，导致夹子的卷绕或收缩，从而近似组织并固定夹子。多个剪辑可以加载到部署设备中，该设备被校准为一次部署和保护一个剪辑。附加的实施例是附接到夹子的针尖，其覆盖实心轴。部署是通过推动或移动夹子部分从轴。多个这些针夹可以定向在圆形环上，其允许快速夹子展开和组织近似，例如用于吻合，以及用于随后的环移除或拆除的方法。

8. 发明申请

US20050021056A1 Leaflet structuring 有权
公开(公告)号：US20050021056A1
公开(公告)日：2005-01-27
申请号：US10927263
申请日：2004-08-25
申请人： Frederick St. Goar , James Fann , Mark Deem , Hanson Gifford , Martin Dieck , Brian Martin , Sylvia Fan , Eric Goldfarb , Kent Dell , Ferolyn Powell
发明人： Frederick St. Goar , James Fann , Mark Deem , Hanson Gifford , Martin Dieck , Brian Martin , Sylvia Fan , Eric Goldfarb , Kent Dell , Ferolyn Powell
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/12 , A61B17/122 , A61B17/128 , A61F2/24
CPC分类号： A61B17/00234 , A61B8/10 , A61B17/04 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0625 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/07207 , A61B17/08 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00783 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/045 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06057 , A61B2017/06076 , A61B2017/061 , A61B2017/06171 , A61B2017/0641 , A61B2017/0649 , A61B2017/088 , A61B2017/2926 , A61B2018/00291 , A61F2/2445 , A61F2/2457
摘要： The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.

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