专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07790432B2 Alanine 2,3-aminomutases and related polynucleotides 有权
标题翻译：丙氨酸2,3-氨基变位酶和相关多核苷酸
公开(公告)号：US07790432B2
公开(公告)日：2010-09-07
申请号：US11919271
申请日：2005-10-25
申请人： Ranjini Chatterjee , Kenneth W. Mitchell , Susan Y. Louie , Richard J. Fox , Michelle Chen
发明人： Ranjini Chatterjee , Kenneth W. Mitchell , Susan Y. Louie , Richard J. Fox , Michelle Chen
IPC分类号： C12N9/88 , C12N1/20 , C12N1/00 , C12N15/00 , C07H21/02
CPC分类号： C12N9/90
摘要： The present invention is directed to polypeptides that have enhanced alanine 2,3-aminomutase (AAM) activity and/or thermostability relative to the wild-type enzymes that have incidental AAM activity as a result of cross reactivity with alanine. In addition, the present invention is directed to a polynucleotides that encodes for the AAM polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the AAM polypeptides, and to a method for producing the AAM polypeptides of the present invention.
摘要翻译：本发明涉及相对于具有与丙氨酸交叉反应性的结果具有附带的AAM活性的野生型酶具有增强的丙氨酸2,3-氨基变位酶（AAM）活性和/或热稳定性的多肽。此外，本发明涉及编码本发明的AAM多肽的多核苷酸，包含多核苷酸的核酸序列与包含与启动子可操作连接的多核苷酸的表达载体，转染以表达AAM的宿主细胞多肽，以及用于制备本发明的AAM多肽的方法。

2. 发明申请

US20100099143A1 Alanine 2,3-aminomutases and related polynucleotides 有权
公开(公告)号：US20100099143A1
公开(公告)日：2010-04-22
申请号：US11919271
申请日：2005-10-25
申请人： Ranjini Chatterjee , Kenneth W. Mitchell , Susan Y. Louie , Richard J. Fox , Michelle Chen
发明人： Ranjini Chatterjee , Kenneth W. Mitchell , Susan Y. Louie , Richard J. Fox , Michelle Chen
IPC分类号： C12P21/02 , C12N9/10 , C12N15/11 , C12N15/00 , C12N1/21
CPC分类号： C12N9/90
摘要： The present invention is directed to polypeptides that have enhanced alanine 2,3-aminomutase (AAM) activity and/or thermostability relative to the wild-type enzymes that have incidental AAM activity as a result of cross reactivity with alanine. In addition, the present invention is directed to a polynucleotides that encodes for the AAM polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the AAM polypeptides, and to a method for producing the AAM polypeptides of the present invention.

3. 发明申请

US20120040437A1 ALANINE 2,3-AMINOMUTASES AND RELATED POLYNUCLEOTIDES 审中-公开
标题翻译： ALANINE 2,3-AMINOMUTASES和相关多核苷酸
公开(公告)号：US20120040437A1
公开(公告)日：2012-02-16
申请号：US13223604
申请日：2011-09-01
申请人： Svetlana Balatskaya , Birthe Borup , Ranjini Chatterjee , Ish Dhawan , Richard J. Fox , Kenneth W. Mitchell , Emily C. Mundorff , Les Partridge , Matthew Tobin
发明人： Svetlana Balatskaya , Birthe Borup , Ranjini Chatterjee , Ish Dhawan , Richard J. Fox , Kenneth W. Mitchell , Emily C. Mundorff , Les Partridge , Matthew Tobin
IPC分类号： C12N9/90
CPC分类号： C12N9/90 , C12P13/06
摘要： The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides.
摘要翻译：本公开一般涉及具有改进的丙氨酸2,3-氨基变位酶（AAM）活性的多肽，编码AAM多肽的多核苷酸，以及用于表达AAM多肽的表达载体和宿主细胞。

4. 发明申请

US20100248312A1 Alanine 2,3-aminomutases and related polynucleotides 有权
标题翻译：丙氨酸2,3-氨基变位酶和相关多核苷酸
公开(公告)号：US20100248312A1
公开(公告)日：2010-09-30
申请号：US11581946
申请日：2006-10-16
申请人： Svetlana Balatskaya , Birthe Borup , Ranjini Chatterjee , Ish Dhawan , Richard J. Fox , Kenneth W. Mitchell , Emily C. Mundorff , Les Partridge , Matthew Tobin
发明人： Svetlana Balatskaya , Birthe Borup , Ranjini Chatterjee , Ish Dhawan , Richard J. Fox , Kenneth W. Mitchell , Emily C. Mundorff , Les Partridge , Matthew Tobin
IPC分类号： C12P13/06 , C12N9/90 , C07H21/04 , C12N15/63 , C12N1/20
CPC分类号： C12N9/90 , C12P13/06
摘要： The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides.
摘要翻译：本公开一般涉及具有改进的丙氨酸2,3-氨基变位酶（AAM）活性的多肽，编码AAM多肽的多核苷酸，以及用于表达AAM多肽的表达载体和宿主细胞。

5. 发明授权

US08030051B2 Alanine 2,3-aminomutases and related polynucleotides 有权
标题翻译：丙氨酸2,3-氨基变位酶和相关多核苷酸
公开(公告)号：US08030051B2
公开(公告)日：2011-10-04
申请号：US11581946
申请日：2006-10-16
申请人： Svetlana Balatskaya , Birthe Borup , Ranjini Chatterjee , Ish Dhawan , Richard J. Fox , Kenneth W. Mitchell , Emily C. Mundorff , Les Partridge , Matthew Tobin
发明人： Svetlana Balatskaya , Birthe Borup , Ranjini Chatterjee , Ish Dhawan , Richard J. Fox , Kenneth W. Mitchell , Emily C. Mundorff , Les Partridge , Matthew Tobin
IPC分类号： C12N9/90 , C12N1/20 , C12N15/70 , C12P13/06
CPC分类号： C12N9/90 , C12P13/06
摘要： The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides.
摘要翻译：本公开一般涉及具有改进的丙氨酸2,3-氨基变位酶（AAM）活性的多肽，编码AAM多肽的多核苷酸，以及用于表达AAM多肽的表达载体和宿主细胞。

6. 发明授权

US6131903A Signature stripping mechanism 失效
标题翻译：签名剥离机制
公开(公告)号：US6131903A
公开(公告)日：2000-10-17
申请号：US357633
申请日：1999-07-20
申请人： Karl P. Schaefer , Ingermar S. d'Agrella , John M. Neary , Richard J. Fox
发明人： Karl P. Schaefer , Ingermar S. d'Agrella , John M. Neary , Richard J. Fox
IPC分类号： B65H29/40 , B65H29/54
CPC分类号： B65H29/54 , B65H29/40 , B65H2404/656 , B65H2511/10
摘要： An adjustable signature stripping mechanism for stripping signatures from a rotating bucket assembly in a folder of a printing press. The mechanism includes a stripper shaft having a mounting portion and a pivot axis and a plurality of strippers mounted on the stripper shaft for stripping signatures from the bucket assembly and wherein the strippers are non-rotatable relative to the stripper shaft and slidable positionable along the stripper shaft.
摘要翻译：一种可调节的签名剥离机构，用于从印刷机的文件夹中的旋转桶组件剥离签名。该机构包括具有安装部分和枢转轴线的剥离器轴和安装在汽提器轴上的多个剥离器，用于剥离来自铲斗组件的签名，并且其中剥离器相对于剥离器轴不可旋转并且可沿着剥离器定位轴。

7. 发明授权

US4242789A Method for making an improved magnetic encoding device 失效
标题翻译：制造改进磁编码装置的方法
公开(公告)号：US4242789A
公开(公告)日：1981-01-06
申请号：US21291
申请日：1979-03-16
申请人： Richard J. Fox
发明人： Richard J. Fox
IPC分类号： G06K19/02 , G06K19/12
CPC分类号： G06K19/02 , G06K19/12 , Y10T29/49863 , Y10T29/49906
摘要： A magnetic encoding device and method for making the same are provided for use as magnetic storage mediums in identification control applications which give output signals from a reader that are of shorter duration and substantially greater magnitude than those of the prior art. Magnetic encoding elements are produced by uniformly bending wire or strip stock of a magnetic material longitudinally about a common radius to exceed the elastic limit of the material and subsequently mounting the material so that it is restrained in an unbent position on a substrate of nonmagnetic material. The elements are spot weld attached to a substrate to form a binary coded array of elements according to a desired binary code. The coded substrate may be enclosed in a plastic laminate structure. Such devices may be used for security badges, key cards, and the like and may have many other applications.
摘要翻译：提供了用于制造该磁性编码装置的磁性编码装置及其制造方法，用作识别控制应用中的磁性存储介质，其给出了读取器的输出信号，该信号的持续时间较短并且比现有技术大得多。磁性编码元件是通过将磁性材料的线材或条状原料纵向围绕公共半径均匀地弯曲而超过材料的弹性极限并随后安装材料以使其被限制在非磁性材料的基底上的无位置上而制成的。这些元件是附着到基底上的点焊，以根据期望的二进制代码形成元件的二进制编码阵列。编码的基底可以封装在塑料层压结构中。这样的设备可以用于安全徽章，钥匙卡等，并且可以具有许多其他应用。

8. 发明申请

US20130030178A1 METHODS OF MAKING HIV ATTACHMENT INHIBITOR PRODRUG COMPOUND AND INTERMEDIATES 有权
标题翻译：制备HIV附着抑制剂制剂化合物和中间体的方法
公开(公告)号：US20130030178A1
公开(公告)日：2013-01-31
申请号：US13359708
申请日：2012-01-27
申请人： Jonathan Clive Tripp , Dayne Dustan Fanfair , Mitchell J. Schultz , Saravanababu Murugesan , Richard J. Fox , Chung-Pin H. Chen , Sabrina E. Ivy , Joseph Francis Payack , Wendel W. Doubleday
发明人： Jonathan Clive Tripp , Dayne Dustan Fanfair , Mitchell J. Schultz , Saravanababu Murugesan , Richard J. Fox , Chung-Pin H. Chen , Sabrina E. Ivy , Joseph Francis Payack , Wendel W. Doubleday
IPC分类号： C07F9/6561 , C07D471/04
CPC分类号： C07D471/04 , C07F9/6561
摘要： A method for making the compound of Formula I: is set forth using alkylation, amidation, chlorination and phosphate installation procedures.
摘要翻译：制备式I化合物的方法使用烷基化，酰胺化，氯化和磷酸盐安装方法进行说明。

9. 发明申请

US20090298125A1 HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES 有权
标题翻译：盐酸脱氢酶和相关多核苷酸
公开(公告)号：US20090298125A1
公开(公告)日：2009-12-03
申请号：US12505374
申请日：2009-07-17
申请人： S. Christopher Davis , Richard J. Fox , Gjalt W. Huisman , Vesna Gavrilovic , Emily C. Mundorff , Lisa M. Newman
发明人： S. Christopher Davis , Richard J. Fox , Gjalt W. Huisman , Vesna Gavrilovic , Emily C. Mundorff , Lisa M. Newman
IPC分类号： C12P21/06 , C12N9/00 , C07H21/04 , C12N15/63 , C12N1/19
CPC分类号： C12N9/14 , C12N9/88
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译：本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。本发明还提供相关载体，宿主细胞和方法。

10. 发明授权

US06869549B2 Method and mold for making ophthalmic devices 有权
标题翻译：用于制造眼科装置的方法和模具
公开(公告)号：US06869549B2
公开(公告)日：2005-03-22
申请号：US10228719
申请日：2002-08-27
申请人： Scott Frederick Ansell , Michael W. Litwin , Gregory L. Berckmiller , Timothy P. Freeman , Richard J. Fox , Robert B. Phillips , Thomas R. Daniels , Richard F. Barbas , Gerald R. Krebsbach
发明人： Scott Frederick Ansell , Michael W. Litwin , Gregory L. Berckmiller , Timothy P. Freeman , Richard J. Fox , Robert B. Phillips , Thomas R. Daniels , Richard F. Barbas , Gerald R. Krebsbach
IPC分类号： G02C7/04 , B29C33/38 , B29C33/40 , B29C33/44 , B29C45/14 , B29C45/26 , B29D11/00
CPC分类号： B29D11/0048 , B29C33/3842 , B29C33/40 , B29C33/44 , B29C45/2673 , B29C2045/2679 , B29D11/00125 , B29L2011/0041 , B29L2031/757 , Y10S425/808
摘要： This invention provides a method and a mold for improving the release of a molded ophthalmic device from a mold. The method comprises the steps of: providing a first mold half and second mold half each having opposing top surfaces at least one of which has been hollowed out to define a cavity for forming said ophthalmic device and at least said first mold half further defining a boundary for a release element, said boundary is part of said cavity, said release element comprising a ramped surface, said cavity having a corresponding ramped surface, and said release element having its widest part near the top surface of said at least said first mold half that defines said release element therein. The mold of this invention has a hollowed-out portion as part of the cavity to provide a release element to the molded ophthalmic device.
摘要翻译：本发明提供一种用于改进模制眼科装置从模具中释放的方法和模具。该方法包括以下步骤：提供第一半模和第二半模，其具有相对的顶表面，其中至少一个已被挖空以形成用于形成所述眼科装置的空腔，并且至少所述第一半模进一步限定边界所述释放元件包括倾斜表面，所述空腔具有相应的倾斜表面，并且所述释放元件具有靠近所述至少所述第一半模的上表面的最宽部分，在其中限定所述释放元件。本发明的模具具有作为空腔的一部分的中空部分，以向模制的眼科装置提供释放元件。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式