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1. 发明授权

US08498721B2 Coronary vein leads having pre-formed biased portions for fixation 有权
标题翻译：冠状静脉引导具有预先形成的用于固定的偏置部分
公开(公告)号：US08498721B2
公开(公告)日：2013-07-30
申请号：US13251466
申请日：2011-10-03
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having a pre-formed biased portion is adapted for implantation with a body vessel and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预成形的偏置部分的引线适于用身体容器注入并连接到信号发生器。引线被构造和布置成使得当其被植入时，电极通过预先形成的偏压部分朝向血管壁偏压，该部分操作以将引线固定在血管壁上。

2. 发明申请

US20120215294A1 CORONARY VEIN LEADS HAVING PRE-FORMED BIASED PORTIONS FOR FIXATION 有权
标题翻译：具有用于固定的预先形成的偏心部分的冠状动脉引导
公开(公告)号：US20120215294A1
公开(公告)日：2012-08-23
申请号：US13251466
申请日：2011-10-03
申请人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having a pre-formed biased portion is adapted for implantation with a body vessel and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预成形的偏置部分的引线适于用身体容器注入并连接到信号发生器。引线被构造和布置成使得当其被植入时，电极通过预先形成的偏压部分朝向血管壁偏压，该部分操作以将引线固定在血管壁上。

3. 发明授权

US06584362B1 Leads for pacing and/or sensing the heart from within the coronary veins 有权
公开(公告)号：US06584362B1
公开(公告)日：2003-06-24
申请号：US09651340
申请日：2000-08-30
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall. A method for implanting the lead into the coronary vasculature is also provided, the method comprising the steps of inserting a stylet into the lead, inserting the lead into the coronary sinus, advancing the lead from the coronary sinus toward the toward the left atrium and into a coronary vein, removing the stylet, and sensing and pacing the heart. Alternatively, the method comprises placing a guide catheter into the coronary sinus, threading a guide wire into the coronary veins, pushing the lead over the guide wire and into the coronary sinus or the coronary vein, and sensing and pacing the heart via the lead in its implanted site in the coronary sinus or the coronary vein.

4. 发明授权

US07139614B2 Leads for pacing and/or sensing the heart from within the coronary veins 有权
公开(公告)号：US07139614B2
公开(公告)日：2006-11-21
申请号：US10431136
申请日：2003-05-07
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall. A method for implanting the lead into the coronary vasculature is also provided, the method comprising the steps of inserting a stylet into the lead, inserting the lead into the coronary sinus, advancing the lead from the coronary sinus toward the toward the left atrium and into a coronary vein, removing the stylet, and sensing and pacing the heart. Alternatively, the method comprises placing a guide catheter into the coronary sinus, threading a guide wire into the coronary veins, pushing the lead over the guide wire and into the coronary sinus or the coronary vein, and sensing and pacing the heart via the lead in its implanted site in the coronary sinus or the coronary vein.

5. 发明授权

US07628801B2 Coronary vein leads having an atraumatic tip and method therefor 有权
标题翻译：冠状静脉引导具有无创伤的尖端及其方法
公开(公告)号：US07628801B2
公开(公告)日：2009-12-08
申请号：US10128997
申请日：2002-04-23
申请人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61F7/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having an atraumatic tip is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by a preformed biased portion. Near the distal end, the lead has an optional tapered portion and a flexible portion, where the flexible portion is more flexible than the biased portion.
摘要翻译：具有无创尖端的引线适于植入在冠状脉管系统内或心脏周围并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先偏置的部分偏压到血管壁。在远端附近，引线具有可选的锥形部分和柔性部分，其中柔性部分比偏置部分更柔性。

6. 发明申请

US20100049288A1 CORONARY VEIN LEAD HAVING PRE-FORMED BIASED PORTIONS FOR FIXATION 有权
标题翻译：具有用于固定的预形成偏心部分的冠状动脉引导
公开(公告)号：US20100049288A1
公开(公告)日：2010-02-25
申请号：US12608402
申请日：2009-10-29
申请人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having pre-formed biased portion is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预形成偏置部分的引线适于植入在冠状脉管系统内部或周围的心脏上，并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先设定的偏压部分偏压到血管壁，该部分操作以将引线固定在血管壁上。

7. 发明授权

US08050775B2 Coronary vein lead having pre-formed biased portions for fixation 有权
标题翻译：冠状静脉引线具有用于固定的预先形成的偏置部分
公开(公告)号：US08050775B2
公开(公告)日：2011-11-01
申请号：US12608402
申请日：2009-10-29
申请人： Randy Westlund , Bruce A. Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce A. Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having pre-formed biased portion is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预形成偏置部分的引线适于植入在冠状脉管系统内部或周围的心脏上，并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先设定的偏压部分偏压到血管壁，该部分操作以将引线固定在血管壁上。

8. 发明授权

US07412290B2 Seal for use with medical device and system 失效
标题翻译：用于医疗器械和系统的密封
公开(公告)号：US07412290B2
公开(公告)日：2008-08-12
申请号：US10968305
申请日：2004-10-20
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

9. 发明授权

US06240321B1 Expandable seal for use with medical device and system 有权
标题翻译：用于医疗设备和系统的可扩展密封件
公开(公告)号：US06240321B1
公开(公告)日：2001-05-29
申请号：US09133310
申请日：1998-08-12
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N105
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

10. 发明授权

US06901288B2 Sealing assembly for intravenous lead 有权
标题翻译：密封组件用于静脉引导
公开(公告)号：US06901288B2
公开(公告)日：2005-05-31
申请号：US09970195
申请日：2001-10-02
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N1/05 , A61N1/362
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

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